International Journal of Clinical Pharmacy OnlineFirst articles

20.04.2024 | Research Article

Cost-effectiveness analysis of fruquintinib in Chinese patients with refractory metastatic colorectal cancer

Reevaluation of Fruquintinib's Cost-Effectiveness: The study’s findings suggest that fruquintinib, following price reductions and policy changes in China, should be reassessed for its cost-effectiveness in treating refractory metastatic colorectal …

verfasst von:: Zijia Huang, Lingyan Zhou, Hanrui Zheng, Mei Zhan

20.04.2024 | Research Article

Clinical impact of an individualised clinical pharmacy programme into the memory care pathway of older people: an observational study

Polypharmacy and the use of potentially inappropriate medications with a cognitive iatrogenic risk are common in the treatment of older patients with a cognitive complaint. As a team member of the Memory care pathway, the pharmacist can identify …

verfasst von:: Teddy Novais, Elsa Reallon, Julie Martin, Marine Barral, Pierre Krolak-Salmon, Marie-Hélène Coste, Hanane Zenagui, Antoine Garnier-Crussard, Delphine Hoegy, Christelle Mouchoux

20.04.2024 | Research Article

Delabeling of allergy to beta-lactam antibiotics in hospitalized patients: a prospective study evaluating cost savings

Beta-lactam allergy label affects a significant percentage of the population (approximately 10% of the US population) and implies the use of alternative antibiotics associated with higher mortality and healthcare costs. Delabeling beta-lactam …

verfasst von:: Miriam Sobrino-García, Francisco J. Muñoz-Bellido, Esther Moreno-Rodilla, Rita Martín-Muñoz, Aránzazu García-Iglesias, Ignacio Dávila

Open Access 18.04.2024 | Research Article

Assessing feasibility of conducting medication review with follow-up among older adults at community pharmacy: a pilot randomised controlled trial

The study emphasized the feasibility issues of conducting medication review with follow-up at community pharmacies, focusing on recruitment, retention, questionnaire administration and time costs. The findings highlighted a signal of improvement in …

verfasst von:: Christina Malini Christopher, Ali Qais Blebil, KC Bhuvan, Deepa Alex, Mohamed Izham Mohamed Ibrahim, Norhasimah Ismail, Mark Wing Loong Cheong

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18.04.2024 | Research Article

Exploring the impact of anticholinergic burden on urinary independence: insights from a post-stroke cohort of older adults

Post-stroke patients undergoing convalescent rehabilitation may be prescribed anticholinergic medications and should be aware of anticholinergic adverse events. Increased anticholinergic burden during convalescent rehabilitation was negatively …

verfasst von:: Ayaka Matsumoto, Yoshihiro Yoshimura, Fumihiko Nagano, Sayuri Shimazu, Ai Shiraishi, Yoshifumi Kido, Takahiro Bise, Aomi Kuzuhara, Kota Hori, Takenori Hamada, Kouki Yoneda, Kenichiro Maekawa

17.04.2024 | Short Research Report

Adverse events of nivolumab plus ipilimumab versus nivolumab plus cabozantinib: a real-world pharmacovigilance study

The present study identified distinctive differences in adverse event profiles between nivolumab plus ipilimumab and nivolumab plus cabozantinib combination therapies in the two largest real-world databases. Our findings will contribute to the …

verfasst von:: Yurie Oka, Jun Matsumoto, Tatsuaki Takeda, Naohiro Iwata, Takahiro Niimura, Aya Fukuma Ozaki, Kensuke Bekku, Hirofumi Hamano, Motoo Araki, Keisuke Ishizawa, Yoshito Zamami, Noritaka Ariyoshi

17.04.2024 | Author Correction

Author Correction: Assessing safety concerns of interstitial lung disease associated with antibody-drug conjugates: a real-world pharmacovigilance evaluation of the FDA adverse event reporting system

verfasst von:: Wanlong Lin, Jiabing Xu, Yufang Liao, Xiuxian Lin, Jianhui Yang, Wei Zhuang

17.04.2024 | Review Article

A systematic review of the impact of simulation on students’ confidence in performing clinical pharmacy activities

By identifying effective simulation techniques that bolster students' confidence, our review highlights the use of simulation and different types of simulation in clinical pharmacy education. Our research not only uncovers a spectrum of simulation …

verfasst von:: Jean-François Huon, Pierre Nizet, Sophie Tollec, Elise Vene, Clémentine Fronteau, Alison Leichnam, Martine Tching-Sin, Vanessa Michelet-Barbotin, Laura Foucault-Fruchard, Fabien Nativel

Open Access 09.04.2024 | Commentary

Novel opportunities for clinical pharmacy research: development of a machine learning model to identify medication related causes of delirium in different patient groups

The advent of artificial intelligence (AI) technologies has taken the world of science by storm in 2023. The opportunities of this easy to access technology for clinical pharmacy research are yet to be fully understood. The development of a …

verfasst von:: Anita Elaine Weidmann, Edward William Watson

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03.04.2024 | Review Article

An umbrella review of the diagnostic value of next-generation sequencing in infectious diseases

Metagenomic next-generation sequencing (mNGS) offers advantages over conventional methods, mainly when rare pathogens are involved or when patients are on antibiotics. This umbrella analysis indicates that mNGS is a promising technique for …

verfasst von:: Hong Cao, Yan Chen, Long Ge, Joey Sum-wing Kwong, Honghao Lai, Fangfang Hu, Rui Zhang, Huaye Zhao, Linfang Hu, Rui He, Wenyi Zheng, Jiaxing Zhang

Open Access 03.04.2024 | Review Article

Clinical pharmacy key performance indicators for hospital inpatient setting: a systematic review

This systematic review evaluated the quality of key performance indicators for clinical pharmacy through the Appraisal of Indicators through Research and Evaluation (AIRE) instrument. Key performance indicators for clinical pharmacy were developed …

verfasst von:: Lucas Magedanz, Hiolanda Lêdo Silva, Dayani Galato, Fernando Fernandez-Llimos

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29.03.2024 | Research Article

Clinical risk assessment of modelled situations in a pharmaceutical decision support system: a modified e-Delphi exploratory study

Using modeled situations standardizes large-scale data collection to prevent clinical risks. The impact of the clinical pharmacist is more easily documented using the clinical risk level associated with the modeled PDSS situations, rather than that …

verfasst von:: Juline Bouet, Arnaud Potier, Bruno Michel, Céline Mongaret, Mathias Ade, Alexandre Dony, Anne-Sophie Larock, Édith Dufay

29.03.2024 | Research Article

Polypharmacy and medication regimen complexity in transfusion-dependent thalassaemia patients: a cross- sectional study

High treatment complexity is not directly associated with poor iron overload control but rather mediated by drug-related problems. Constant monitoring of iron overload is essential in patients with high medication regimen complexity index and …

verfasst von:: Geok Ying Chun, Sharon Shi Min Ng, Farida Islahudin, Veena Selvaratnam, Nurul Ain Mohd Tahir

29.03.2024 | Research Article

Critical care pharmacy service provision and workforce in adult extracorporeal membrane oxygenation centres: a multicentre cross-sectional survey

Most responding ECMO centres in the UK reported pharmacy staffing ratios below nationally agreed standards. High variability exists in clinical pharmacy services to ECMO patients over 7 days in the UK. Future work should address gaps in clinical …

verfasst von:: Christopher Remmington, Lynda Cameron, Fraser Hanks, Ya-Hui Liang, Linda Barrow, Ruth Coxhead, Reena Mehta, Nisha Bhudia, Haifa Lyster, Sarah Cooke, James Gilmartin, Phillisa Lee, Rhona Sloss, Cathrine McKenzie

Open Access 29.03.2024 | Research Article

Community pharmacists’ views and experiences of delivering in-pharmacy medication reviews for people living with severe and persistent mental illness: a qualitative study

Pharmacists were motivated to support people living with SPMI through in-pharmacy medication review services, if appropriate training in mental health for pharmacists and pharmacy staff is provided. Policy makers should consider alternative …

verfasst von:: Ricki Ng, Sarira El-Den, Jack C. Collins, Sara S. McMillan, Jie Hu, Amanda J. Wheeler, Claire L. O’Reilly

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Open Access 15.03.2024 | Research Article

Implementation of medication reviews in community pharmacy: reaching consensus on stakeholders’ recommendations for mechanisms of change using the nominal group technique

This theory-driven study presents a model for the implementation of medication reviews in a community pharmacy setting. Prioritised mechanisms of change were deemed to be effective to improve particularly adoption, appropriateness, and feasibility …

verfasst von:: Dorothee E. Michel, Antonella P. Tonna, Dorothee C. Dartsch, Anita E. Weidmann

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15.03.2024 | Review Article

The efficacy of zuranolone versus placebo in postpartum depression and major depressive disorder: a systematic review and meta-analysis

The available antidepressant treatments are not always effective for the treatment of major depressive disorder (MDD) and postpartum depression (PPD), demonstrating a need for a more effective, efficient, and practical solution. The novel drug …

verfasst von:: Mackenzie Winslow, Emily White, Suzanne J. Rose, Elijah Salzer, Eric C. Nemec II

13.03.2024 | Research Article

A qualitative study exploring the challenges and enablers of pharmacists with a recent background in community pharmacy transitioning into primary care

This study describes the challenges and enablers of community pharmacists transitioning into primary care, and provides an understanding of the support required to facilitate this transition. Healthcare organisations should be mindful of the …

verfasst von:: Ian Campbell, Heather Harrison, Amanj Kurdi

Open Access 12.03.2024 | Commentary

Artificial intelligence in academic writing and clinical pharmacy education: consequences and opportunities

The current academic debate on the use of artificial intelligence (AI) in research and teaching has been ongoing since the launch of ChatGPT in November 2022. It mainly focuses on ethical considerations, academic integrity, authorship and the need …

verfasst von:: Anita Elaine Weidmann

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12.03.2024 | Research Article

Availability, price, and affordability of anti-hepatitis B virus drugs: a cross-sectional study in China

The overall availability of anti-HBV drugs in Jiangsu, China, was low, indicating that even with lower prices, the access of residents to drugs was restricted due to insufficient supply. Drug prices in Jiangsu, China, were favorable compared to the …

verfasst von:: Yue Li, Mengdie Zhang, Yi Xu, Xin Li, Tao Lu

Springer Medizin