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Endocrine OnlineFirst articles

11.11.2022 | Original Article

Long-term clinical outcomes and prognostic factors for patients with papillary thyroid carcinoma with other organ invasions after adjuvant radioactive iodine

Papillary thyroid carcinoma (PTC) is the most frequent endocrine malignancy. Its incidence has been increasing over the past several decades [ 1 ]. Thyroidectomy followed by adjuvant radioactive iodine (RAI) and the suppression of …

verfasst von:
Terufumi Kawamoto, Naoto Shikama, Tatsuya Fukumori, Masae Hoshi, Tetsu Yamada

11.11.2022 | COVID-19 | Original Article

The impact of covid-19 on thyroid function tests in pregnancy

The coronavirus disease 2019 (COVID-19), was declared a global pandemic by the World Health Organization (WHO) in March 2020 [ 1 ]. By July 18, 2022, more than 565 million confirmed cases and more than 6 million deaths have been reported worldwide …

verfasst von:
Aysegul Atalay, Berhan Besimoglu, Selcan Sinaci, Ecem Kaya, Onur Ozkavak, Fatma Doga Ocal, Ayse Seval Ozgu-Erdinc, Dilek Sahin

Open Access 10.11.2022 | Correction

Correction to: Making sense of diabetes medication decisions: a mixed methods cluster randomized trial using a conversation aid intervention

verfasst von:
Marleen Kunneman, Megan E. Branda, Jennifer L. Ridgeway, Kristina Tiedje, Carl R. May, Mark Linzer, Jonathan Inselman, Angela L. H. Buffington, Jordan Coffey, Deborah Boehm, James Deming, Sara Dick, Holly van Houten, Annie LeBlanc, Juliette Liesinger, Janet Lima, Joanne Nordeen, Laurie Pencille, Sara Poplau, Steven Reed, Anna Vannelli, Kathleen J. Yost, Jeanette Y. Ziegenfuss, Steven A. Smith, Victor M. Montori, Nilay D. Shah

10.11.2022 | Meta- Analysis

Association between the history of abortion and gestational diabetes mellitus: A meta-analysis

Gestational diabetes mellitus (GDM) is a common endocrine metabolic disease defined as hyperglycemia caused by glucose intolerance that begins or is first diagnosed in pregnancy [ 1 ]. The prevalence of hyperglycemia in pregnancy increases with …

verfasst von:
Hao Wang, Xianwei Guo, Qiuxia Song, Wanying Su, Muzi Meng, Chenyu Sun, Ning Li, Qiwei Liang, Guangbo Qu, Mingming Liang, Xiuxiu Ding, Yehuan Sun

09.11.2022 | Original Article

Metabolic effects of dopamine-agonists treatment among patients with prolactinomas

Prolactinoma is one of the most prevalent pituitary adenomas affecting about 40% of all pituitary adenoma patients [ 1 ]. It is speculated that high prolactin (PRL) level is associated with the increased risk of cardiovascular morbidity, and …

verfasst von:
Maryam Kabootari, Habibeh Shirmohammadli, Fatemeh Golgiri, Seyedarad Mosalamiaghili, Alireza Khajavi, Hamideh Akbari

09.11.2022 | Brief report

Novel IGFALS mutations with predicted pathogenetic effects by the analysis of AlphaFold structure

IGFALS is a 2 exons-containing gene, located on chromosome 16p13.3 and encoding the Insulin-like growth factor-binding protein acid-labile subunit (ALS) having a mass of 84 to 86 kD. ALS is produced in the liver and is present almost exclusively in …

verfasst von:
Alessandra Franzoni, Federica Baldan, Nadia Passon, Catia Mio, Daniela Driul, Paola Cogo, Federico Fogolari, Federica D’Aurizio, Giuseppe Damante

Open Access 09.11.2022 | COVID-19 | Original Article

Hypocalcemia is associated with adverse outcomes in patients hospitalized with COVID-19

In December 2019, in China, SARS-CoV-2 ( Severe Acute Respiratory Syndrome Coronavirus 2) was identified as the causative agent of a cluster of pneumonia of unknown origin. The infection, due to its rapid global spread, in March 2020, was declared …

verfasst von:
Alessandro Minasi, Aikaterini Andreadi, Alessio Maiorino, Luca Giudice, Sofia De Taddeo, Ilenia D’Ippolito, Ilaria de Guido, Rossella Laitano, Maria Romano, Valeria Ruotolo, Andrea Magrini, Nicola Di Daniele, Paola Rogliani, Alfonso Bellia, Davide Lauro

09.11.2022 | Original Article

Prediabetes is more than a pre-disease: additional evidences supporting the importance of its early diagnosis and appropriate treatment

Type 2 diabetes (T2D) is a serious and growingly costly problem for the health system worldwide, and Argentina is not an exception: its prevalence in the period 2005–2018 grew by 51% (from 8.4 to 12.7%) [ 1 ]. Its clinical and metabolic dysfunction …

verfasst von:
J. F. Elgart, R. Torrieri, M. Ré, M. Salazar, W. Espeche, J. M. Angelini, C. Martínez, J. Martínez, C. Giampieri, G. Etchegoyen, J. P. Ricart, M. E. Rodríguez, J. J. Gagliardino

09.11.2022 | Original Article

Expression of the angiogenesis markers endocan in Cushing’s syndrome due to cortisol producing adenoma

Cushing’s syndrome (CS) is defined as a clinical condition caused by chronic glucocorticoid excess due to various causes. CS of endogenous origin is classified as adrenocorticotropic hormone (ACTH)-dependent CS (Cushing’s Disease; CD) and …

verfasst von:
Mustafa Can, Muhammet Kocabaş, Melia Karaköse, Hacı Hasan Esen, Mustafa Kulaksızoğlu, Feridun Karakurt

Open Access 07.11.2022 | Original Article

Impact of fasting on thyrotropin and thyroid status during Ramadan in 292 previously well controlled hypothyroid patients. IFTAR study

Levothyroxine (L-T4) - being the mainstay treatment for hypothyroidism - has been one of the top ten prescribed medications in the past decade [ 1 ]. However, 11% to 42% of hypothyroid patients on L-T4 are under-replaced [ 2 ]. Low or non-adherence …

verfasst von:
Tamer Mohamed Elsherbiny

Open Access 05.11.2022 | Original Article

An analysis of the utilisation of medical identification jewellery among children and young adults with type 1 diabetes mellitus in Australia

Diabetes mellitus (DM) is a chronic metabolic disorder that is characterised by abnormal carbohydrate metabolism and chronic hyperglycaemia. Elevated blood glucose levels are either the result of defective insulin production, defective insulin …

verfasst von:
Madeleine Heath, David J. Torpy, Rosemary Louise Rushworth

Open Access 04.11.2022 | Original Article

Silencing FOXP2 reverses vemurafenib resistance in BRAFV600E mutant papillary thyroid cancer and melanoma cells

Thyroid carcinoma (TC) is the most common malignancy of the endocrine system. As of 2020, the incidence of TC has continually increased, and approximately 4.1% of patients with TC are expected to die from malignancy [ 1 ]. Papillary thyroid …

verfasst von:
Suyuan Jiang, Yuxin Huang, Yuan Li, Qin Gu, Cuiping Jiang, Xiaoming Tao, Jiao Sun

Open Access 03.11.2022 | Review

Screening and management of major endocrinopathies during pregnancy: an update

Endocrinopathies during pregnancy constitute a challenging issue, being prevalent and requiring appropriate management to avoid maternal and fetal complications. This review aims to summarize and present major endocrine problems during pregnancy …

verfasst von:
Stavroula A. Paschou, Evanthia Bletsa, Maria Papazisi, Nikoletta Mili, Fotini Kanouta, Georgia N. Kassi, Theodora Psaltopoulou, Dimitrios G. Goulis, Irene Lambrinoudaki

01.11.2022 | Original Article

Giant growh hormone-secreting pituitary adenomas from the endocrinologist’s perspective

Acromegaly is a disorder characterized by systemic manifestations secondary to excess growth hormone (GH) and insulin-like growth factor-1 (IGF-1) exposure. Benign monoclonal GH-secreting pituitary adenomas that originate from pituitary …

verfasst von:
Bahadir Koylu, Busra Firlatan, Suleyman Nahit Sendur, Seda Hanife Oguz, Selcuk Dagdelen, Tomris Erbas

Open Access 30.10.2022 | Original Article

Filling the gap between the heart and the body in acromegaly: a case-control study

Acromegaly is a rare chronic disease, characterised by overproduction of growth hormone (GH), mainly caused by anterior pituitary tumours. Long-term presence of elevated GH and insulin-like growth factor 1 (IGF-1) levels accompanying this disease …

verfasst von:
Ivana Ságová, Milan Dragula, Marián Mokáň, Peter Vaňuga

30.10.2022 | Review

Growth alterations in rare forms of primary adrenal insufficiency: a neglected issue in paediatric endocrinology

Primary adrenal insufficiency (PAI) is an endocrine disorder characterized by direct adrenal failure, with consequent glucocorticoid, and eventually mineralocorticoid, deficiency. In children, the main cause of PAI is congenital adrenal …

verfasst von:
Rosario Ferrigno, Daniela Cioffi, Valeria Pellino, Maria Cristina Savanelli, Antonella Klain

28.10.2022 | Original Article

Hypocalcemia after parathyroidectomy in patients with a history of bariatric surgery

Obesity is associated with significant morbidity and mortality [ 1 ], and its prevalence continues to rise worldwide [ 2 ]. Bariatric surgery, which includes Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), gastric band (GB), and …

verfasst von:
F. Jeffrey Lorenz, David Goldenberg

28.10.2022 | Original Article

Serum 25 hydroxyvitamin D concentrations in individuals over 80 years old and their correlations with musculoskeletal and health parameters

The world’s population is ageing, and chronic diseases, dependence, reduced quality of life and increased social costs will be challenges for public health systems worldwide, especially in developing countries. Between 2010 and 2050, the …

verfasst von:
Mariana Zuccolotto Foroni, Maysa Seabra Cendoroglo, Eliane Naomi Sakane, Rosangela Villa Marin-Mio, Patricia Ferreira do Prado Moreira, Sergio Setsuo Maeda, Marise Lazaretti-Castro

27.10.2022 | Mini Review

Pesticides as endocrine disruptors: programming for obesity and diabetes

The environment has a strong influence on human life, especially in developing stages, such as pregnancy, lactation, childhood, and adolescence. These periods are considered “plastic”, i.e., phases that are marked by the intense development of the …

verfasst von:
Rosiane Aparecida Miranda, Beatriz Souza Silva, Egberto Gaspar de Moura, Patrícia Cristina Lisboa

26.10.2022 | Review

Vitamin D in the older population: a consensus statement

The 5th International Conference “Controversies in Vitamin D” was held in Stresa, Italy, 15–18 September 2021 as part of this series that started in 2017 [ 1 – 7 ]. The objective of this conference, which featured international experts and leaders …

verfasst von:
Andrea Giustina, Roger Bouillon, Bess Dawson-Hughes, Peter R. Ebeling, Marise Lazaretti-Castro, Paul Lips, Claudio Marcocci, John P. Bilezikian