Neurocritical Care OnlineFirst articles

17.04.2024 | Neuroimage

Biphasic Clinical Trajectory in Pneumococcal Meningitis from Cerebral Infarcts

verfasst von:: Valeria Ariza Hutchinson, Sherri A. Braksick, Norbert G. Campeau, Eelco F. M. Wijdicks

15.04.2024 | Review Article

Survivorship After Neurocritical Care: A Scoping Review of Outcomes Beyond Physical Status

Following intensive care unit hospitalization, survivors of acute neurological injury often experience debilitating short-term and long-term impairments. Although the physical/motor impairments experienced by survivors of acute neurological injury …

verfasst von:: Jamie Nicole LaBuzetta, Dale N. Bongbong, Eric Mlodzinski, Richa Sheth, Aaron Trando, Nicholas Ibrahim, Brandon Yip, Atul Malhotra, Victor D. Dinglas, Dale M. Needham, Biren B. Kamdar

15.04.2024 | Neurocritical Care Through History

A Comatose State in Search of a Name: A History of Its Terminology and Semiology

The terminology has changed considerably, and we are still struggling to name this elusive neurologic state. For many neurologists, the destruction of the brain was not debatable, but when comparing equally severe injuries, why did they find some …

verfasst von:: Eelco F. M. Wijdicks

Open Access 15.04.2024 | Original work

Analysis of Cerebral Spinal Fluid Drainage and Intracranial Pressure Peaks in Patients with Subarachnoid Hemorrhage

Subarachnoid hemorrhage (SAH) caused by a rupture of an intracranial aneurysm (aSAH) is a severe life-threatening emergency that is characterized by an acute onset of symptoms and is associated with considerable rates of morbidity and mortality [ 1 …–

verfasst von:: Anton Früh, Peter Truckenmüller, David Wasilewski, Peter Vajkoczy, Stefan Wolf, for the Earlydrain Study Group

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15.04.2024 | Neuroimage

Point-of-Care Ultrasound to Rapidly Detect a Malpositioned Ventriculoperitoneal Shunt

verfasst von:: Daniel Freeman, Erika Sigman

Open Access 11.04.2024 | Original work

Covert Consciousness in Acute Brain Injury Revealed by Automated Pupillometry and Cognitive Paradigms

Each year, an estimated 2 in 1,000 people fall into a coma and enter the intensive care unit (ICU) [ 1 ]. Of all patients who do not immediately recover and show overt signs of consciousness, around 15–20% may be awake and aware despite being …

verfasst von:: Marwan H. Othman, Markus Harboe Olsen, Karen Irgens Tanderup Hansen, Moshgan Amiri, Helene Ravnholt Jensen, Benjamin Nyholm, Kirsten Møller, Jesper Kjaergaard, Daniel Kondziella

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08.04.2024 | Original work

Mortality, Functional Status, and Quality of Life after 5 Years of Patients Admitted to Critical Care for Spontaneous Intracerebral Hemorrhage

Cerebral hemorrhage is a frequent, serious pathology with high mortality [ 1 – 5 ]. Patients with cerebral hemorrhage also make up a large group of intensive care unit (ICU) patients with high in-hospital mortality [ 6 – 10 ]. There are few …

verfasst von:: Marina Gordillo-Resina, Consuelo Aranda-Martinez, Maria Dolores Arias-Verdú, Francisco Guerrero-López, Encarnación Castillo-Lorente, David Rodríguez-Rubio, Ricardo Rivera-López, Carmen Rosa-Garrido, Francisco Javier Gómez-Jiménez, Jesus Lafuente-Baraza, Eduardo Aguilar-Alonso, Miguel Angel Arráez-Sánchez, Ricardo Rivera-Fernández

08.04.2024 | Original work

The Impact of Enteral Nimodipine on Endothelial Cell Apoptosis in an Animal Subarachnoid Hemorrhage Model

Brain injury caused by subarachnoid hemorrhage (SAH) after rupture of a cerebral aneurysm is divided into early brain injury and delayed brain injury [ 1 , 2 ]. The pathophysiologic mechanisms of early brain damage are known to be an immediate …

verfasst von:: Young Dae Cho, Hyoung Soo Byoun, Kwang Hyon Park, Young Il Won, Jeongwook Lim

08.04.2024 | Original work

Evaluation of Post-thrombolytic Events to Determine Appropriate ICU Monitoring Duration for Patients with Ischemic Stroke

Acute ischemic stroke (AIS) is a significant cause of morbidity and mortality in the United States [ 1 ]. Standard treatment for selected patients presenting with AIS within 4.5 h of symptom onset is thrombolysis with tissue plasminogen activators …

verfasst von:: James Reimer, Fajun Wang, Joanna Ramiro, Emily Welch, Kara M. Christopher, James Braun

Open Access 05.04.2024 | Review Article

Efficacy and Tolerability of Intranasal Midazolam Administration for Antiseizure Treatment in Adults: A Systematic Review

Rapid antiseizure treatment is crucial for persistent, prolonged, or recurrent epileptic seizures. The majority of epileptic seizures spontaneously cease within a few minutes [ 1 ]. However, cases that involve prolonged convulsive seizure activity …

verfasst von:: Tolga D. Dittrich, Dominik Vock, Urs Fisch, Lisa Hert, Sira M. Baumann, Paulina S.C. Kliem, Stephan Rüegg, Stephan Marsch, Gian Marco De Marchis, Raoul Sutter

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05.04.2024 | Original work

A Recruitment Maneuver After Apnea Testing Improves Oxygenation and Reduces Atelectasis in Organ Donors After Brain Death

Apnea testing is an integral component of the determination of death by neurologic criteria, also known as brain death [ 1 ]. However, removing a patient with brain injury from a ventilator can be associated with serious complications [ 2 – 4 ].

verfasst von:: Rajat Dhar, Porche Braun, Atul Kumar, Jayesh Patel, Flavia L. Lee, Baback Arshi

03.04.2024 | Neurocritical Care Through History

The Self-Confirmatory History of Plasmapheresis and IVIG

verfasst von:: Eelco F. M. Wijdicks

03.04.2024 | Original work

Multidisciplinary Consensus on Curricular Priorities for Pediatric Neurocritical Care Nursing Education: A Modified Delphi Study in the United States

The field of pediatric neurocritical care (PNCC) is a distinct specialty that requires integrating knowledge of pediatric health care systems, childhood neurological and neurosurgical diseases, and developmental central nervous system (CNS) …

verfasst von:: Nathan Chang, Lauren Louderback, Heather Hammett, Kara Hildebrandt, Erica Prendergast, Amelia Sperber, May Casazza, Megan Landess, Aubree Little, Lindsey Rasmussen, the Pediatric Neurocritical Care Research Group Nursing Committee

03.04.2024 | Invited Commentary

CPPopt on Medical Devices: The Imitation Game

verfasst von:: Erta Beqiri

02.04.2024 | Original work

Effect of Statin Treatment in Patients with Aneurysmal Subarachnoid Hemorrhage: A Network Meta-Analysis

Subarachnoid hemorrhage (SAH) occurs in approximately 9 per 100,000 people yearly, mainly due to the rupture of intracranial aneurysms [ 1 , 2 ]. About half of patients with SAH are younger than 55 years old, with an inferior prognosis. Up to 75% …

verfasst von:: Xing Wang, Qi Gan, Chao You, Lu Ma

Open Access 01.04.2024 | Original work

Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium: Randomized Controlled Trial

Delirium, a newly recognized but increasingly prevalent complication in the intensive care unit (ICU), casts a shadow over a critically ill patient. Defined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, as a “sudden …

verfasst von:: Tamer Zakhary, Islam Ahmed, Ibrahim Luttfi, Mina Montasser

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01.04.2024 | Original work

Association of Serum Macrophage Migration Inhibitory Factor with 3-Month Poor Outcome and Malignant Cerebral Edema in Patients with Large Hemispheric Infarction

Large hemispheric infarction (LHI) is a serious subtype of acute ischemic stroke (AIS) and is associated with high mortality [ 1 – 3 ]. More than 50% of patients experiencing an LHI will develop malignant cerebral edema (MCE). MCE reaches its peak …

verfasst von:: Wen Guo, Mangmang Xu, Xindi Song, Yajun Cheng, Yilun Deng, Ming Liu

01.04.2024 | Neurocritical Care Through History

Fast and Deep Breathing in Acute Brain Injury

Plum and Swanson were the first to describe brain lesion–associated hyperventilation causing hypocarbia [ 2 ]. The article reports nine patients with acute lesions in the pons, mostly caused by acute embolus to the basilar artery, and compared them …

verfasst von:: Eelco F. M. Wijdicks

26.03.2024 | Neurocritical Care Through History

The Pupil as Indicator of a Cranial Vault Under Pressure: On Sir William Macewen contributions

Macewan’s classic article from 1887 provided the best description of pupillary changes and is full of detailed observations (Fig. 1 ) [ 3 ]. In one patient, he astutely observes four periods, each with a “peculiar pupillary condition.” The first …

verfasst von:: Eelco F. M. Wijdicks

21.03.2024 | Viewpoint

The Quest to Revise the Uniform Determination of Death Act: Why We Tried, Why We Failed, and Where We Go from Here

Clinician interactions with families, lawsuits, and academic discussions raised five concerns with the UDDA [ 2 – 4 , 6 – 14 ] (Table 1 ). The two concerns that are most relevant to clinical practice are about the need for consent for BD/DNC …

verfasst von:: Ariane Lewis

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin