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Journal of Gastrointestinal Cancer OnlineFirst articles

15.09.2021 | Original Research

Management and Survival Analysis of Gastrointestinal Neuroendocrine Tumors by Different Tumor Characteristics: Tertiary Center Experience

Gastrointestinal neuroendocrine tumors (GI-NETs) are tumors formed by neuroendocrine cell communities that can secrete different hormones depending on the region where they occur and cause different clinics due to these hormone secretions [ 1 ].

Autoren:
Bedia Gonulal, Yilmaz Bilgic, Sami Akbulut, Ertugrul Karabulut, Emine Turkmen Samdanci

14.09.2021 | Original Research Open Access

The Glasgow Prognostic Score Before Curative Resection May Predict Postoperative Complications in Patients with Gastric Cancer

Gastric cancer (GC) is the fifth most prevalent carcinoma in the world, with 1,089,103 new cases in 2020, and the fourth leading cause of death from cancer, with 768,793 deaths globally [ 1 ]. The standard treatment for pathological (p)stage II/III …

Autoren:
Yota Shimoda, Hirohito Fujikawa, Keisuke Komori, Hayato Watanabe, Kosuke Takahashi, Kazuki Kano, Takanobu Yamada, Manabu Shiozawa, Soichiro Morinaga, Kenji Katsumata, Akihiko Tsuchida, Takashi Ogata, Takashi Oshima

14.09.2021 | COVID-19 | Review Article Zur Zeit gratis

The Impact of the COVID-19 Epidemic on Diagnosis, Treatment, Concerns, Problems, and Mental Health in Patients with Gastric Cancer

In late 2019, a type of pneumonia caused by coronavirus 19 was recognized as a global epidemic with a significant impact on global health [ 1 ]. This pandemic caused the death of more than one million people also caused many people suffering and …

Autoren:
Fatemeh Baghernezhad Hesary, Hamid Salehiniya

12.09.2021 | Original Research

Epidemiologic and Pathologic Study of Pancreatic Cancer in Hamadan, Iran (2008 to 2018)

Pancreatic cancer is the one of leading causes of cancer mortality in developed countries and one of the most lethal malignant neoplasms across the world. Most pancreatic cancers are adenocarcinoma, whereas other slower-growing pancreatic cancers …

Autoren:
Elham Khanlarzadeh, Saman Nazari, Mehdi Ghobakhlou, Hossein Ranjbar, Sasan Nazari

09.09.2021 | Review Article

Barriers and Facilitators Associated with Delays in the Diagnosis and Treatment of Gastric Cancer: a Systematic Review

Gastric cancer is a cancer that develops from the lining of the stomach and may spread to other parts of the body, especially the liver, lungs, bones, abdominal tissue, and lymph nodes [ 1 ]. It is also one of the most common and deadly neoplasms …

Autoren:
Afrooz Mazidimoradi, Zohre Momenimovahed, Hamid Salehiniya

09.09.2021 | Original Research

Hypermethylation of MIR129-2 Regulates SOX4 Transcription and Associates with Metastasis in Patients with Colorectal Cancer

Colorectal cancer (CRC) is ranked as the third most frequently occurring cancer in the world and one of the most leading causes of tumor-related mortality in the USA [ 1 ]. Epidemiological studies have estimated that the incidence rate of CRC in …

Autoren:
Alireza Rezayi Soufiani, Roya Dolatkhah, Mortaza Raeisi, Hadi Chavoshi, Payam Mohammadi, Abdolreza Mehdinavaz Aghdam

06.09.2021 | Original Research

Utilization of Mutational Analysis (MA) in Gastrointestinal Stromal Tumor (GIST) Management in British Columbia (BC) Between January 2008 to December 2017: a Retrospective Population-Based Study

New tyrosine kinase inhibitors (TKIs) for metastatic gastrointestinal stromal tumor (GIST) and the emergence of other novel treatment options have changed the treatment landscape for patients with metastatic GIST [ 1 – 4 ]. Prior to 2015 …

Autoren:
Tiffany Patterson, Jocelyn Chai, Haocheng Li, Angeline de bruyns, Chantell Cleversey, Cheng-Han Lee, Steven Yip, Christine Simmons, Jason Hart, Phil Pollock, Caroline Holloway, Pauline Truong, Xiaolan Feng

06.09.2021 | Original Research Open Access

Analysis of Post-operative Adjuvant Chemotherapy Versus Adjuvant Chemoradiation Therapy Outcomes in Non-metastatic Cholangiocarcinoma: an NCDB Review

With an incidence of approximately 8000 cases annually in the USA, cholangiocarcinoma is a rare form of cancer [ 1 ]. Recent studies are beginning to demonstrate the complex nature of this disease, with important implications stemming from its …

Autoren:
Robin R. Rodriguez, Stephen Abel, Jyothika Mamadgi, Paul B. Renz, Rodney E. Wegner, Moses S. Raj

06.09.2021 | Review Article

Mitochondrial DNA Copy Number Variations in Gastrointestinal Tract Cancers: Potential Players

Alterations of mitochondria have been linked to several cancers. Also, the mitochondrial DNA copy number (mtDNA-CN) is altered in various cancers, including gastrointestinal tract (GIT) cancers, and several research groups have investigated its …

Autoren:
Mehdi Alikhani , Eliette Touati, Morteza Karimipoor, Massoud Vosough, Marjan Mohammadi

04.09.2021 | Original Research

Pancreaticoduodenectomy: Impact of Volume on Outcomes at a Tertiary Care Center—Our Experience in Single Institute of Nepal

Pancreatic cancer remains one of the cancers with the poorest prognosis, with an overall 5-year survival rate of about 5%, without much difference between high-income countries and low-income and middle-income countries [ 1 ].

Autoren:
Sunit Agrawal, Bhawani Khanal, Ujjwal Das, Suresh Prasad Sah, Rakesh Kumar Gupta

03.09.2021 | Original Research

Moderate Prognostic Value of lncRNA FOXD2-AS1 in Gastric Cancer with Helicobacter pylori Infection

Gastric cancer is the third cause of cancer-related death worldwide and takes more than 700,000 death every year [ 1 , 2 ]. LncRNAs are non-coding RNAs longer than 200 nt are involved in a wide range of cellular functions such as regulation of …

Autoren:
Ali Rajabi, Sepideh Bastani, Melika Maydanchi, Samaneh Tayefeh-Gholami, Sepehr Abdolahi, Ali Saber, Reza Safaralizadeh

03.09.2021 | Review Article

The Role of Tumor Necrosis Factor-α (TNF-α) Polymorphisms in Gastric Cancer: a Meta-Analysis

Gastric cancer (GC) is one of the most aggressive malignancies worldwide accounted for about 783,000 deaths and over 1,000,000 new cases in 2018 [ 1 ]. Several factors may have a role in cancer such as genetics, helicobacter pylori, chronic …

Autoren:
Maryam Gholamalizadeh, Samaneh Mirzaei Dahka, Hadi Sedigh Ebrahim-Saraie, Mohammad Esmail Akbari, Azam Pourtaheri, Samira Rastgoo, Azadeh Hajipour, Afshin Shafaghi, Saied Doaei, Naser Kalantari

01.09.2021 | Original Research

Anticancer Activity of Aqueous Fenugreek Seed Extract Against Pancreatic Cancer, Histological Evidence

Cancer remains a major public health problem worldwide. Pancreatic cancer (PC) is a disease caused due to DNA mutations which can be inherited or acquired as a person ages. Although the actual cause is not known, there are several environmental …

Autoren:
Daklallah Ahmed Almalki, Deyala M. Naguib

01.09.2021 | Original Research

Histopathological, Radiological, and Demographic Factors Predicting the Response to Neoadjuvant Therapy for Rectal Cancer

According to the 2018 GLOBOCAN data of the World Health Organisation (WHO), colorectal cancer (CRC) constitutes 11% of all cancer diagnoses, is the third most commonly diagnosed cancer worldwide, and is the third most common cause of …

Autoren:
Emine Yildirim, Sibel Bektas, Zekeriya Pelen, Irem Yanik, Ahmet Muzaffer Er, Ferhat Cengel, Perihan Özkan Gumuskaya

31.08.2021 | Original Research

Association of PARK-2 Non-synonyms Polymorphisms and Their In Silico Validation Among North Indian Colorectal Cancer Patients

Globally, colorectal cancer is the third most commonly diagnosed cancer in males and the second in females with more than 1.4 million new cancer cases every year [ 1 ]. In India, lakhs of new incidences are reported every year. The age standardized …

Autoren:
Zafar Iqbal Bhat, Afreen Naseem, Bhupender Kumar, Kalaiarasan Ponnusamy, Raj Ranjan Tiwari, G. D. Sharma, M. Moshahid Alam Rizvi

31.08.2021 | Review Article

The Activity and Polymorphism of the PON1 in Patients with Chronic Liver Disease: a Systematic Review and Meta-analysis

The liver weighs approximately 1500 g, is the largest internal organ, and the most important organ after the heart and brain in the human body, without which, it is impossible to survive [ 1 ]. Liver disease is one of the top 10 deadliest diseases …

Autoren:
Nader Salari, Mohsen Kazeminia, Kamran Mansouri, Amin Hosseinian-Far, Masoud Mohammadi

31.08.2021 | Original Research

Extra-Colonic Malignancy in Inflammatory Bowel Disease: a Paucity of Recommendations with Weak Evidence

Patients with inflammatory bowel disease (IBD) are at notable risk for the development of both colonic and extra-colonic malignancies. Colorectal cancer (CRC) remains the third most diagnosed malignancy and the second leading cause of …

Autoren:
Simcha Weissman, Muhammad Aziz, Matthew R. Baniqued, Mohamed Ahmed, Sameh Elias, Joseph D. Feuerstein, James H. Tabibian

31.08.2021 | Case Report

A Case of Myasthenia Gravis with Two Primary Tumors: Paraneoplastic or Incidental?

Pancreatic neuroendocrine tumors (pNETs) are well-differentiated pancreatic neuroendocrine neoplasia composed of neuroendocrine cells [ 1 ]. They constitute 1–2% of all pancreatic neoplasia with an incidence of 0.8/100,000 [ 2 ]. Overall, 60–90% of …

Autoren:
Tuba Uğur, Fatih Gürler, Bülent Cengiz, Reha Kuruoğlu, Ahmet Özet

31.08.2021 | Invited Paper

Systematic Analysis of Cytostatic TGF-Beta Response in Mesenchymal-Like Hepatocellular Carcinoma Cell Lines

Liver cancer is the sixth most prevalent cancer worldwide, with 905,677 new cases diagnosed in 2020, and the third leading cause of cancer-related death. Hepatocellular carcinoma (HCC) is the most common type of liver cancer, accounting for nearly …

Autoren:
Medine Zeynep Gungor, Merve Uysal, Mehmet Ozturk, Serif Senturk

27.08.2021 | Editorial

GADD45aa as a Predictive Biomarker for Aeromonas Infection–Related Liver Cirrhosis

Autoren:
Hamid Sadeghi, Nematollah Gheibi, Saeideh Gholamzadeh Khoei