Circulating tumor DNA (ctDNA) consists of DNA fragments released from cancer cells into the blood circulation with quick clearance. Analysis of ctDNA can enable real-time assessment of the presence of cancer cells and their genomic …
According to data from the World Health Organization (WHO) in 2020, there were about 2.3 million newly diagnosed breast cancer patients and 685,000 deaths from breast cancer in women worldwide. Breast cancer is a heterogeneous disease with …
verfasst von:
Pei-Jing Yang, Eing-Mei Tsai, Ming-Feng Hou, Yen-Jung Lee, Tsu-Nai Wang
Neoadjuvant or preoperative chemotherapy (NACT), defined as the administration of chemotherapy before surgery, was initially the standard treatment for patients with locally advanced breast cancer. Currently, it is becoming a commonly used option …
Breast cancer is a heterogeneous disease, and accurate determination of basic biomarkers including estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) is crucial for selecting appropriate …
verfasst von:
Sei Na, Milim Kim, Yujun Park, Hyun Jung Kwon, Hee-Chul Shin, Eun-Kyu Kim, Mijung Jang, Sun Mi Kim, So Yeon Park
Despite substantial advances in therapy, advanced breast cancer (ABC) remains an incurable disease with a 5-year survival rate of ~ 25% [ 1 ]. Of the different disease subtypes, hormone receptor-positive (HR+)/human epidermal growth factor receptor …
Triple-negative breast cancer (TNBC) is a highly heterogeneous tumor lacking estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression. It has higher aggressiveness and metastasis than other …
Mammography screening has demonstrated its effectiveness in reducing breast-cancer mortality in many randomized controlled trials conducted in Europe and the United States [ 1 ]. However, one of the problems associated with breast-cancer screening …
The world has experienced significant growth of technology implementation in daily living activities, with Artificial Intelligence (AI) occupying a predominant position [ 1 ]. Voice recognition, self-driving cars, and online translation software …
verfasst von:
Karla C. Maita, Francisco R. Avila, Ricardo A. Torres-Guzman, John P. Garcia, Gioacchino D. De Sario Velasquez, Sahar Borna, Sally A. Brown, Clifton R. Haider, Olivia S. Ho, Antonio Jorge Forte
Breast-conserving surgery (BCS) followed by whole-breast irradiation (WBI) is an established treatment for early breast cancer. According to a previous meta-analysis, WBI following BCS reduced the risk of recurrence within 10 years by 15.7% (35.0% …
verfasst von:
Peter J. K. Tokuda, Takamasa Mitsuyoshi, Yuka Ono, Takahiro Kishi, Yoshiharu Negoro, Setsuko Okumura, Itaru Ikeda, Takashi Sakamoto, Yumi Kokubo, Ryo Ashida, Toshiyuki Imagumbai, Mikiko Yamashita, Hiroaki Tanabe, Sayaka Takebe, Mariko Tokiwa, Eiji Suzuki, Chikako Yamauchi, Michio Yoshimura, Takashi Mizowaki, Masaki Kokubo, the Kyoto Radiation Oncology Study Group
Triple-negative breast cancer (TNBC) accounts for 15% of metastatic breast cancers, has a poorer prognosis, and represents a high unmet medical need [ 1 ]. Therapeutic progress has been made in recent years, with the established benefit of …
verfasst von:
Alexandre De Moura, Delphine Loirat, Sarah Vaillant, Sinen Korbi, Nicolas Kiavue, Diana Bello Roufai, Laurence Escalup, Romain Desmaris, Pauline Vaflard, Paul Cottu, Jean-Yves Pierga, François-Clément Bidard, Luc Cabel, Alexandre Acramel
Breast cancer is the most commonly diagnosed type of cancer among women worldwide. Approximately 2.3 million new cases of breast cancer were diagnosed worldwide in 2020 [ 1 ], and approximately 680,000 women died from the disease [ 1 ]. Early …
Adjuvant endocrine therapy is recommended for patients with estrogen receptor (ER)-positive and human epidermal growth factor receptor type 2 (HER2)-negative (i.e., luminal type) breast cancer [ 1 , 2 ], whereas additional chemotherapy is required …
Nipple-sparing mastectomy (NSM) is an oncological surgical procedure that has been accepted for certain patient populations. This procedure allows patients to preserve the native nipple–areolar complex (NAC) and facilitates immediate …
verfasst von:
Sayuri Kato, Hiroki Mori, Miho Saiga, Satoko Watanabe, Shinsuke Sasada, Ayano Sasaki, Akiko Ogiya, Mao Yamamoto, Kazutaka Narui, Junji Takano, Hirohito Seki, Naomi Nagura, Makoto Ishitobi, Tadahiko Shien, the Collaborative Study Group of Scientific Research of the Japanese Breast Cancer Society
The number of breast cancer patients is increasing annually [ 1 ]. Simultaneously, the percentage of women choosing breast reconstruction after mastectomy is increasing and has doubled from 13% in 1998 to 26% in 2007 and continues to rise [ 2 , 3 …
verfasst von:
Joep A. F. van Rooij, Ennie Bijkerk, René R. J. W. van der Hulst, Stefania M. H. Tuinder
The Breast Cancer Clinical Practice Guidelines, organized by the Japanese Breast Cancer Society (JBCS), were published in 2022. We present the English version of the Radiation Therapy (RT) section of the guidelines. The JBCS formed a task force to …
Breast cancer is the most prevalent malignancy affecting women worldwide, including Japanese women [ 1 , 2 ]. In recent years, neoadjuvant chemotherapy (NAC) has gained widespread use in early-stage breast cancer patients. Initially, NAC was …
verfasst von:
Hiroko Nogi, Akiko Ogiya, Makoto Ishitobi, Chikako Yamauchi, Hiroki Mori, Ayaka Shimo, Kazutaka Narui, Naomi Nagura, Hirohito Seki, Shinsuke Sasada, Teruhisa Sakurai, Tadahiko Shien, The Collaborative Study Group of Scientific Research of The Japanese Breast Cancer Society
The Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer, 2022 Edition was published in June 2022. The guidelines were prepared while conforming as much as possible to the “Minds Manual for Guideline Development 2020 ver.
Breast cancer is the most commonly diagnosed cancer and is the second leading cause of cancer death among women in the United States (US) [ 1 , 2 ]. Neoadjuvant chemotherapy (NACT), a systemic therapy given before surgery, is the standard of care …
verfasst von:
Dan Lin, Kathleen M. Sturgeon, Joshua E. Muscat, Shouhao Zhou, Andrea L. Hobkirk, Katie M. O’Brien, Dale P. Sandler, Cheryl L. Thompson
