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World Journal of Pediatrics OnlineFirst articles

World Journal of Pediatrics OnlineFirst articles

22.09.2018 | Correction

Correction to: Phlegmonous appendicitis in children is characterized by eosinophilia in white blood cell counts

The original article can be found online.

Maximiliane I. Minderjahn, Dag Schädlich, Josephine Radtke, Karin Rothe, Marc Reismann

14.09.2018 | Letter to Editor

Octreotide treatment for neonatal chylothorax

Carlo Bellini, Laura Costanza De Angelis, Tommaso Bellini

14.09.2018 | Review Article

Two decades of off-label prescribing in children: a literature review

The thalidomide disaster (phocomelia in newborns) and the effect of using chloramphenicol in children (gray baby syndrome) triggered the beginning of the drug licensing process. The main aim of drug licensing is to ensure drug quality, safety and …

Shamala Balan, Mohamed Azmi Ahmad Hassali, Vivienne S. L. Mak

10.09.2018 | Original Article Open Access

Leptin gene polymorphism affects leptin level in childhood asthma

Asthma is the most common chronic disease of childhood. It is characterized by both local inflammation in the airways as well as low grade systemic inflammation. One of the peptides involved in various inflammatory diseases is leptin, a hormone …

Dawid Szczepankiewicz, Paulina Sobkowiak, Beata Narożna, Irena Wojsyk-Banaszak, Anna Bręborowicz, Aleksandra Szczepankiewicz

28.08.2018 | Original Article

Calcium-handling abnormalities underlying atrial arrhythmogenesis in a Fontan operation canine model

The Fontan operation is a well-established surgical technique used for palliation of complex cyanotic congenital heart disease such as tricuspid atresia, double-inlet ventricle, or single ventricle defect [ 1 ]. Although mortality in Fontan …

Wan-Ping Zhou, Fen Li, Jin-Jin Wu, Ya-Nan Lu, Yi-Jiao Qian

28.08.2018 | Review Article

Chinese guidelines for the assessment and provision of nutrition support therapy in critically ill children

To promote and regulate the nutrition support therapy in critically ill children and to encourage corresponding academic research, a group of experts from the Emergency Group of Chinese Pediatrics Society, Pediatrics group of Chinese Emergency …

Xue-Mei Zhu, Su-Yun Qian, Guo-Ping Lu, Feng Xu, Ying Wang, Chun-Feng Liu, Xiao-Xu Ren, Yu-Cai Zhang, Heng-Miao Gao, Tao Zhou, Hong-Xing Dang, Chong-Fan Zhang, Yi-Min Zhu

28.08.2018 | Original Article

Molecular and epidemiologic characterization of Wilms tumor from Baghdad, Iraq

Wilms tumor (WT) is the most common childhood kidney cancer worldwide, and its incidence varies with race [ 1 , 2 ]. Globally, black children of sub-Saharan African ancestry consistently show the highest incidence of WT regardless of nationality …

Hannah M. Phelps, Mazin F. Al-Jadiry, Natasha M. Corbitt, Janene M. Pierce, Bingshan Li, Qiang Wei, Raina R. Flores, Hernan Correa, Stefania Uccini, Haydar Frangoul, Adel R. Alsaadawi, Safaa A. F. Al-Badri, Amir F. Al-Darraji, Raghad M. Al-Saeed, Salma A. Al-Hadad, Harold N. Lovvorn III

15.08.2018 | Commentary

Early prediction of acute kidney injury in children: known biomarkers but novel combination

The concept of acute renal failure (ARF) has undergone significant re-examination in recent years. Mounting evidence suggests that acute, relatively mild injury to the kidney or impairment of kidney function manifests by changes in urine output …

Qian Lin, Jian-Hua Mao

31.07.2018 | Review article

Pregnancy and child developmental outcomes after preimplantation genetic screening: a meta-analytic and systematic review

Forty years have passed since the first child conceived through in vitro fertilization (IVF) was born in 1978. Despite impressive technological and scientific advances, the rate of success (i.e., having a healthy baby) is far from patient …

Misaki N. Natsuaki, Laura M. Dimler

30.07.2018 | Original Article

Surgical outcome after complete repair of tetralogy of Fallot with absent pulmonary valve: comparison between bovine jugular vein-valved conduit and monocusp-valve patch

Absent pulmonary-valve (APV) syndrome is a rare malformation that was first described by Chevers in 1846 [ 1 , 2 ]. It occurs in 3–6% patients with tetralogy of Fallot (TOF/APV) [ 3 , 4 ]. The malformation comprises rudimentary or nearly APV—with …

En-Shi Wang, Xue-Song Fan, Li Xiang, Shou-Jun Li, Hao Zhang

25.07.2018 | Original Article

Determinants for asthma control, quality of life and use of complementary and alternative medicine in asthmatic pediatric patients in four cities

Asthma is a significant chronic health problem worldwide [ 1 ]. The prevalence of asthma has increased two- to threefold over the past three decades in industrialized countries and there is evidence to suggest that this prevalence continues to …

Kam Lun Hon, Yan Min Bao, Kate C. Chan, Kin Wai Chau, Rong-Shan Chen, Kun Tat Gary Cheok, Wa Keung Chiu, Li Deng, Chun-Hui He, Kin Mui Ieong, Jeng Sum C. Kung, Ping Lam, Shu Yan David Lam, Qun Ui Lee, So Lun Lee, Ting Fan Leung, Theresa N. H. Leung, Lei Shi, Ka Ka Siu, Wei-Ping Tan, Maggie Haitian Wang, Tak Wai Wong, Bao-Jing Wu, Ada Y. F. Yip, Yue-Jie Zheng, Daniel K. Ng

24.07.2018 | Original Article

Associations of non-high-density lipoprotein cholesterol with metabolic syndrome and its components in Korean children and adolescents: the Korea National Health and Nutrition Examination Surveys 2008–2014

As the pediatric population with overweight and obesity increases, metabolic complications such as the impairment of glucose metabolism, hypertension, and dyslipidemia are recognized as major problems in the field of public health [ 1 ]. The …

Yong Min Kim, So Hyun Kim, Young Suk Shim

24.07.2018 | Original Article

Phlegmonous appendicitis in children is characterized by eosinophilia in white blood cell counts

Appendicitis is one of the most frequent pediatric surgical emergencies. In industrialized countries the lifetime risk for developing acute appendicitis ranges between 7 and 9%. Children of all ages are affected with a peak incidence in …

Maximiliane I. Minderjahn, Dag Schädlich, Josephine Radtke, Karin Rothe, Marc Reismann

28.06.2018 | Original Article

Health correlates, addictive behaviors, and peer victimization among adolescents in China

Peer victimization is a common type of aggression among children and adolescents and a major stressor that could hamper their physical and mental health [ 1 ]. Peer victimization is here defined as “repeated harassment or bullying, including …

Qi-Qi Chen, Meng-Tong Chen, Yu-Hong Zhu, Ko Ling Chan, Patrick Ip

27.06.2018 | Original Article

The availability of probiotics and donor human milk is associated with improved survival in very preterm infants

Despite decreased mortality and morbidity in very preterm and very low birth weight infants, some of them still die; and necrotising enterocolitis (NEC) and infection continue to be ongoing causes of death and chronic illness in this vulnerable …

Janet Sharpe, Mandy Way, Pieter J. Koorts, Mark W. Davies

15.06.2018 | Original Article

High incidence of maternal vitamin B12 deficiency detected by newborn screening: first results from a study for the evaluation of 26 additional target disorders for the German newborn screening panel

Newborn screening (NBS) is a prerequisite for early diagnosis and successful treatment of many severe conditions presenting in the neonatal period or infancy. The German NBS panel currently includes 15 target disorders, including 12 metabolic …

Gwendolyn Gramer, Junmin Fang-Hoffmann, Patrik Feyh, Glynis Klinke, Peter Monostori, Jürgen G. Okun, Georg F. Hoffmann

25.05.2018 | Original Article

Polymorphisms in the promoter region of IL10 gene are associated with virus etiology of infant bronchiolitis

Viral bronchiolitis is the most common reason that infants in the developed world are admitted to the hospital [ 1 ]. Variations in innate immunity, which regulate inflammatory reactions and development of adaptive immunity, may be the reason why …

Annukka Holster, Johanna Teräsjärvi, Juho Vuononvirta, Petri Koponen, Ville Peltola, Merja Helminen, Qiushui He, Matti Korppi, Kirsi Nuolivirta

30.04.2018 | Letter to the Editor

Antibiotic use in children with Kawasaki disease

Seung Beom Han, Soo-Young Lee

20.03.2018 | Letter to the Editor

Children with abnormal DMSA nuclear scan present a higher risk of recurrent febrile urinary tract infections

Luke Harper, Yan Lefevre, Xavier Delforge, David Bourquard, Cyril Ferdynus

16.03.2018 | Original Article

Elevated serum neopterin levels in children with functional constipation: association with systemic proinflammatory cytokines

Functional constipation is one of the most frequently seen functional gastrointestinal disorders in the pediatric age group. Although several clinical, pathophysiological, and epidemiological studies have been carried out, the cause of childhood …

Ceren Cıralı, Emel Ulusoy, Tuncay Kume, Nur Arslan