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Intensive Care Medicine OnlineFirst articles

Open Access 27.11.2023 | What's New in Intensive Care

Palliative care in intensive care

Since its origination from hospice care, the term palliative care has frequently been used interchangeably with end-of-life care. However, the specialty has developed and expanded to involve symptom control, improvement of patient and …

verfasst von:
Martin Neukirchen, Victoria Metaxa, Maximilian S. Schaefer

27.11.2023 | Original

Determinants of fluid use and the association between volume of fluid used and effect of balanced solutions on mortality in critically ill patients: a secondary analysis of the BaSICS trial

The effects of balanced solutions (BS) on the outcome of critically ill patients have been subject to several randomized controlled trials [ 1 – 4 ]. Although a recent meta-analysis suggested a probability of benefit of 0.895 for BS in critically …

verfasst von:
Fernando G. Zampieri, Flavia R. Machado, Vivivane C. Veiga, Luciano C. P. Azevedo, Sean M. Bagshaw, Lucas P. Damiani, Alexandre B. Cavalcanti

27.11.2023 | Editorial

Equity in ARDS trials: some encouraging findings, and the significant work ahead

verfasst von:
Elisabeth Riviello, Sangeeta Mehta

20.11.2023 | From the Inside

Come hell or high water: climate change through the lens of neurocritical care

verfasst von:
David Fischer

20.11.2023 | Original

Selective digestive tract decontamination in critically ill adults with acute brain injuries: a post hoc analysis of a randomized clinical trial

Selective decontamination of the digestive tract (SDD), consisting of an oral antibiotic paste and a gastric antibiotic suspension, combined with a short course of intravenous antibiotics has been extensively studied in critically ill patients [ 1 …

verfasst von:
Paul J. Young, Anthony Devaux, Qiang Li, Laurent Billot, Joshua S. Davis, Anthony Delaney, Simon R. Finfer, Naomi E. Hammond, Sharon Micallef, Ian M. Seppelt, Balasubramanian Venkatesh, John A. Myburgh, the SuDDICU Australia Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group

20.11.2023 | Editorial

Should we give steroids after out-of-hospital cardiac arrest?

verfasst von:
Matthew H. Anstey, Audrey de Jong, Markus B. Skrifvars

20.11.2023 | Correspondence

Exploring elevated D-dimer in ECMO patients: a path to understanding

verfasst von:
Julie Helms, Ferhat Meziani, Eduardo Angles-Cano

15.11.2023 | Letter

Decidual stromal cells for the treatment of severe COVID-19 ARDS

verfasst von:
John Granton, Igor N. Novitzky-Basso, Alexandra Binnie, Jonas Mattsson, on behalf of the DSC Study Group

14.11.2023 | Editorial

Reusable versus single-use ICU equipment: what’s the environmental footprint?

verfasst von:
Forbes McGain, Scott McAlister

14.11.2023 | Correspondence

D-dimer and bleeding during ECMO: the chicken and the egg?

verfasst von:
Marco Giani, Mauro Panigada

Open Access 09.11.2023 | Original

Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

Out-of-hospital cardiac arrest (OHCA) is one of the leading causes of death in Europe, with an annual incidence between 67 and 170 per 100,000 inhabitants and a survival rate of ~ 10% [ 1 ]. Prehospital interventions such as early cardiopulmonary …

verfasst von:
Laust E. R. Obling, Rasmus P. Beske, Martin A. S. Meyer, Johannes Grand, Sebastian Wiberg, Benjamin Nyholm, Jakob Josiassen, Frederik T. Søndergaard, Thomas Mohr, Anders Damm-Hejmdal, Mette Bjerre, Ruth Frikke-Schmidt, Fredrik Folke, Jacob E. Møller, Jesper Kjaergaard, Christian Hassager

Open Access 09.11.2023 | Letter

Role of intravenous ketamine in the pathogenesis of secondary sclerosing cholangitis in critically ill patients: perpetrator or innocent bystander? Answers provided by forensic toxicology

verfasst von:
Silke Leonhardt, Sven Baumann, Christian Jürgensen, Lars Hüter, Julia Leonhardt, on behalf of the Ketamine Cast Research Group

06.11.2023 | Editorial

How I use ultrasound in cardiac arrest

Given the time critical context of cardiac arrest, appropriate leadership and coordination with the US operator is crucial. US assessment must be rapidly performed by a trained operator to obtain all relevant information during chest compressions …

verfasst von:
Adrian Wong, Philippe Vignon, Chiara Robba

03.11.2023 | Original

Identification of genetic profile and biomarkers involved in acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a severe and fatal manifestation of respiratory failure, characterized by diminished lung compliance, tachypnea, and profound hypoxemia [ 1 , 2 ]. The overall incidence of ARDS in intensive care unit …

verfasst von:
Shurui Cao, Huiqin Li, Junyi Xin, Zhenghao Jin, Zhengyu Zhang, Jiawei Li, Yukun Zhu, Li Su, Peipei Huang, Lei Jiang, Mulong Du, David C. Christiani

03.11.2023 | Editorial

De senectute and the art of medicine: how old is too old for ECMO in cardiogenic shock?

verfasst von:
Jordi Riera, Jan Bělohlávek, Christian Jung

Open Access 03.11.2023 | Less is more in Intensive Care

Scheduled intravenous opioids

verfasst von:
Cathrine McKenzie, Yoanna Skrobik, John W. Devlin

03.11.2023 | Letter

Validation of a new data-driven SLOSR ICU efficiency measure compared to the traditional SRU

verfasst von:
Igor Tona Peres, Guilherme Fonseca Ferrari, Amanda Quintairos, Leonardo dos Santos Lourenço Bastos, Jorge Ibrain Figueira Salluh

03.11.2023 | Correspondence

Platelets and fibrinogen matter when bleeding on ECMO

verfasst von:
Christine Lodberg Hvas, Anne-Mette Hvas, Steffen Christensen

31.10.2023 | Correspondence

SHAP Model Explainability in ECMO – PAL mortality prediction: A Critical Analysis. Author’s reply

verfasst von:
Andrew F. Stephens, Michael Šeman, Carol L. Hodgson, Shaun D. Gregory

31.10.2023 | Original

Inflammatory subphenotypes in patients at risk of ARDS: evidence from the LIPS-A trial

The acute respiratory distress syndrome (ARDS) remains a life-threatening syndrome, resulting in high morbidity and mortality [ 1 ]. In patients with ARDS and in mechanically ventilated critically ill patients, two distinct subphenotypes …

verfasst von:
Simone Redaelli, Dario von Wedel, Maxime Fosset, Aiman Suleiman, Guanqing Chen, Julie Alingrin, Michelle N. Gong, Ognjen Gajic, Valerie Goodspeed, Daniel Talmor, Maximilian S. Schaefer, Boris Jung