Sepsis is a life-threatening organ dysfunction caused by dysregulated host responses to infection due to a variety of microorganisms [ 1 ]. The dysregulated immune responses lead to an uncontrolled systemic inflammatory response, with resultant …
verfasst von:
Tjeerd Pieter van Staa, Alexander Pate, Glen P. Martin, Anita Sharma, Paul Dark, Tim Felton, Xiaomin Zhong, Sian Bladon, Neil Cunningham, Ellie L. Gilham, Colin S. Brown, Mariyam Mirfenderesky, Victoria Palin, Diane Ashiru-Oredope
Cryptococcosisca is a global opportunistic infection caused by Cryptococcus neoformans and Cryptococcus gattii yeasts [ 1 ]. The symptoms of cryptococcosis vary widely, from mild pulmonary cases with fever, chills, and cough, to life-threatening …
Since the zoonotic potential of Borna disease virus 1 (BoDV-1) was proven in 2018 [ 1 , 2 ], approximately 50 human cases within endemic regions in southern and eastern Germany have been reported to German health authorities [ 3 ]. Infections lead …
verfasst von:
Markus Bauswein, Ehab Eid, Lisa Eidenschink, Barbara Schmidt, André Gessner, Dennis Tappe, Dániel Cadar, Merle M. Böhmer, Laura Jockel, Nora van Wickeren, Tamara Garibashvili, Isabel Wiesinger, Christina Wendl, Josef G. Heckmann, Klemens Angstwurm, Martin Freyer
Sepsis is a life-threatening syndrome of organ dysfunction caused by a dysregulated host response to infection that affects 50 million patients worldwide annually [ 1 ]. Despite efforts to improve recognition and treatment, sepsis remains an …
verfasst von:
Lisanne Boekhoud, Helena M. E. A. Schaap, Rick L. Huizinga, Tycho J. Olgers, Jan C. ter Maaten, Douwe F. Postma, Hjalmar R. Bouma
As of October 2023, there have been over 770 million confirmed cases of COVID-19 globally, including nearly 7 million deaths [ 1 ]. Since the declaration of the COVID-19 pandemic by the World Health Organization (WHO) in March 2020 [ 2 ], new …
verfasst von:
Myriam Drysdale, Mehmet Berktas, Daniel C. Gibbons, Catherine Rolland, Louis Lavoie, Emily J. Lloyd
Given the potential for transmission and the significant complications that can arise, particularly in individuals with chronic infections, the prevalence of Helicobacter pylori ( H. pylori ) infection and its association with host and …
Diarrhea is generally known as one of the most common diseases especially among children but also in adults. In low-income countries it is a leading cause of death due to poor general health and lack of adequate medical treatment [ 1 ]. However …
verfasst von:
Michaela Rippl, Anton Burkhard-Meier, Ulf Schönermarck, Michael Fischereder
Vertebral Osteomyelitis (VO, syn.: spondylodiscitis) is a severe infection of the spine, and in recent decades, it has become more frequent [ 1 – 3 ]. However, despite wider availability of radiological imaging for the broader public and …
verfasst von:
Vincent Johann Heck, Tobias Prasse, Kristina Klug, Juan Manuel Vinas-Rios, Stavros Oikonomidis, Alexander Klug, Nikolaus Kernich, Maximilian Weber, Nicolas von der Höh, Maximilian Lenz, Sebastian Gottfried Walter, Bastian Himpe, Peer Eysel, Max Joseph Scheyerer
Three years after the 2019 coronavirus (COVID-19) pandemic, the long-term consequences of COVID-19 in terms of prognosis, quality of life and ability to work have become the focus of medical research [ 1 , 2 ]. The World Health Organization (WHO) …
verfasst von:
Katharina S. Appel, Carolin Nürnberger, Thomas Bahmer, Christian Förster, Maria Cristina Polidori, Mirjam Kohls, Tanja Kraus, Nora Hettich-Damm, Julia Petersen, Sabine Blaschke, Isabel Bröhl, Jana Butzmann, Hiwa Dashti, Jürgen Deckert, Michael Dreher, Karin Fiedler, Carsten Finke, Ramsia Geisler, Frank Hanses, Sina M. Hopff, Björn-Erik O. Jensen, Margarethe Konik, Kristin Lehnert, Susana M. Nunes de Miranda, Lazar Mitrov, Olga Miljukov, Jens-Peter Reese, Gernot Rohde, Margarete Scherer, Kristin Tausche, Johannes J. Tebbe, Jörg Janne Vehreschild, Florian Voit, Patricia Wagner, Martin Weigl, Christina Lemhöfer, the NAPKON Study Group
Pneumonia is a leading cause of morbidity and mortality in all age groups [ 1 ]. It remains a clinical diagnosis primarily, based on clinical signs and symptoms, laboratory investigation, and imaging. The gold standard to detect acute infections of …
verfasst von:
Anne-Eva Post, Erik Bathoorn, Douwe F. Postma, Dirk-Jan Slebos, Onno W. Akkerman
In the context of the evolving global health landscape shaped by the COVID-19 pandemic, tuberculosis (TB) is gaining renewed attention as a reemerging threat even in low-endemic countries. Immunological tests such as the tuberculin skin test (TST) …
verfasst von:
Salvatore Rotundo, Maria Teresa Tassone, Francesca Serapide, Alessandro Russo, Enrico Maria Trecarichi
Yeast species are among the primary causative agents of invasive fungal infections. In recent years, invasive infections due to less common species are increasingly reported, partially due to advances in molecular diagnostics and an increase in …
verfasst von:
Bram Spruijtenburg, Bruna Jacomel Favoreto de Souza Lima, Sonia T. Granadillo Tosar, Andrew M. Borman, Cecilie Torp Andersen, Summiya Nizamuddin, Suhail Ahmad, João Nobrega de Almeida Junior, Vânia Aparecida Vicente, Joshua D. Nosanchuk, Jochem B. Buil, Sybren de Hoog, Eelco F. J. Meijer, Jacques F. Meis, Theun de Groot
Vulvovaginal candidiasis (VVC) is a common fungal infection caused by Candida species and is a source of significant morbidity in women from all social classes. [ 1 , 2 ]. About 75% of women will experience at least one episode of VVC, and 40 ~ 45% …
verfasst von:
Xiaoqian Wang, Wenying Wang, Jingjing Li, Ruifang An, Lihong Chen, Jiajing Lin, Dabao Xu, Jin Qiu, Weihua Song, Mijiti Patiman, Hongjie Ruan, Gang Wang, Fengxia Xue, Xu Wang, Xiaowan Luo, Qi Ruan, Ling Shi, Chun Zhang, Lina Hu, Shijin Wang, Hong Shi, Xiaoli Wang, Songling Zhang, Yingxiong Li, Jing Lu, Baojin Wang, Hongyan Xu, Hong Ye, Bei Zhang, Chunlian Zhang, Sumin Qian, Qiong Wu, Wen Jia, Chuan Li, Qinping Liao
Sara Giordana Rimoldi, Riccardo Nodari, Alberto Rizzo, Alessandro Tamoni, Concetta Longobardi, Cristina Pagani, Silvia Grosso, Federica Salari, Laura Galimberti, Pietro Olivieri, Giuliano Rizzardini, Emanuele Catena, Spinello Antinori, Francesco Comandatore, Antonio Castelli, Maria Rita Gismondo
The COVID-19 pandemic has affected hundreds of millions of individuals and caused more than six million deaths. The prolonged pandemic duration and the continual inter-individual transmissibility have contributed to the emergence of a wide variety …
verfasst von:
Dima Hattab, Mumen F. A. Amer, Zina M. Al-Alami, Athirah Bakhtiar
Aspergillus spp. is a ubiquitous saprophytic mold commonly found in soil, water and building materials, capable of causing a wide range of lung diseases, ranging from simple hypersensitivity reactions to an invasive disease with high fatality [ 1 …
verfasst von:
Benedetta Fumarola, Liana Signorini, Silvia Lorenzotti, Paola Lanza, Barbara Saccani, Evelyn Van Hauwermeiren, Alice Mulè, Simone Piva, Matteo Rota, Francesco Zuccalà, Francesco Antonio Rasulo, Matteo Filippini, Alberto Bertazzoli, Giovanni Del Fabro, Alberto Matteelli
