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Cancer Immunology, Immunotherapy OnlineFirst articles

03.12.2019 | Original Article

Proteolytic processing of PD-L1 by ADAM proteases in breast cancer cells

Expression of programmed death ligand 1 (PD-L1) on the surface of tumor cells and its interaction with programmed cell death protein 1 (PD-1) on tumor-infiltrating lymphocytes suppress anti-tumor immunity. In breast tumors, PD-L1 expression levels …

verfasst von:
Yeni Romero, Randi Wise, Anna Zolkiewska

30.11.2019 | Original Article

Interleukin-38 in colorectal cancer: a potential role in precision medicine

Colorectal cancer (CRC) is a leading cause of cancer-related death, partly due to a lack of reliable biomarkers for early diagnosis. To improve the outcome of CRC, it is critical to provide diagnosis at an early stage using promising …

verfasst von:
Feier Chen, Feng Zhang, Zhenyu Tan, Brett D. Hambly, Shisan Bao, Kun Tao

Open Access 27.11.2019 | Correction

Correction to: Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy

The original version of this article unfortunately included a mistake in Fig. 2b where the images of mice in the tumour control group (right), day 30 (bottom) should be removed as the wrong images (duplicate of day 17) were inserted by mistake. At …

verfasst von:
Nadia Mensali, Marit Renée Myhre, Pierre Dillard, Sylvie Pollmann, Gustav Gaudernack, Gunnar Kvalheim, Sébastien Wälchli, Else Marit Inderberg