Rheumatology International OnlineFirst articles

24.04.2024 | Observational Research

Antineutrophil cytoplasmic antibody positivity incidence before and during COVID-19 pandemic

There are many factors associated with the development of autoimmune diseases. It is known that viral infections can be the triggers of these diseases [ 1 , 2 ]. Since the end of 2019, the world has been faced with the global COVID19 pandemic …

verfasst von:: Perković Dijana, Petrić Marin, Petra Šimac, Vodanović Ana, Borić Katarina, Gugo Katarina, Tandara Leida

Open Access 24.04.2024 | Recommendations

A practical guide to estimating treatment effects in patients with rheumatic diseases using real-world data

Estimated treatment effects derived from Randomized Controlled Trials (RCTs) are considered the gold standard in study methodology and are required by regulatory authorities for approval and clinical use. RCTs aim to reduce bias in treatment …

verfasst von:: Are Hugo Pripp, Katarzyna Łosińska, Mariusz Korkosz, Glenn Haugeberg

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24.04.2024 | Observational Research

Physical fitness in adolescent patients with familial Mediterranean fever

Introduction: Familial Mediterranean fever (FMF) is the most frequent monogenic auto-inflammatory disease worldwide responsible for episodes of fever, serositis and musculoskeletal symptoms. Inflammatory attacks are responsible for sedentary …

verfasst von:: Inès Elhani, Pascal Heydacker, Anne-Sophie Tavernier, Sophie Georgin-Lavialle, Véronique Hentgen

Open Access 22.04.2024 | Observational Research

Barriers and facilitators to implementation of an exercise and education programme for osteoarthritis: a qualitative study using the consolidated framework for implementation research

Targeted efforts to better understand the barriers and facilitators of stakeholders and healthcare settings to implementation of exercise and education self-management programmes for osteoarthritis (OA) are needed. This study aimed to explore the …

verfasst von:: Avantika Bhardwaj, Christine FitzGerald, Margaret Graham, Anne MacFarlane, Norelee Kennedy, Clodagh M. Toomey

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17.04.2024 | Case Based Review

Management of granulomatosis with polyangiitis complicated by intestinal perforation and pancytopenia: a case report and literature review

Granulomatosis with polyangiitis is a systemic vasculitis. While the classic triad typically comprises otorhinolaryngologic, pulmonary, and renal manifestations, it is essential to recognize that granulomatosis with polyangiitis can affect any …

verfasst von:: Svitlana Smiyan, Olena Dyadyk, Oksana Kvasnitska, Olexandra Makhovska, Zhanna Antiuk, Taras Bidovanets, Roman Komorovsky

16.04.2024 | Patient Opinion

Patient-reported outcomes of curcumin supplementation in rheumatoid arthritis and psoriatic arthritis: a cross-sectional survey

Curcumin is suggested to possess potent anti-inflammatory properties. This study focuses on determining the prevalence and perceived efficacy of curcumin supplementation in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) population. We …

verfasst von:: Richa Purohit, Neha Bhaskar, Tara Jehu, Kathlyn Camargo Macias, Sweta Chalise, Neha Bhanusali

16.04.2024 | Systematic Review

Renal manifestations in adult-onset Still’s disease: a systematic review

Adult-onset Still’s disease (AOSD) is a rare multisystem inflammatory disorder characterized primarily by fever, evanescent rash, and arthralgias. The reported prevalence is 0.73–6.77 per 100,000 population [ 1 ]. In 1897, G F Still described 22 …

verfasst von:: P. V. Akhila Arya, Erica Marnet, Madhumita Rondla, Jia Wei Tan, Dileep Unnikrishnan, Gregory Buller

Open Access 14.04.2024 | Observational Research

The temporal association between adverse drug reactions and antirheumatic drugs utilisation in Western Australia: a retrospective study from real-world data (1995–2015)

Adverse drug reactions (ADRs) are potentially avoidable causes of morbidity, mortality, and healthcare utilisation [ 1 ]. The Quality in Australian Healthcare study estimated that 51% of ADRs were preventable, 18% of ADRs spent more than 10 extra …

verfasst von:: Khalid B. Almutairi, Charles A. Inderjeeth, David B. Preen, Helen I. Keen, Johannes C. Nossent

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Open Access 12.04.2024 | Protocols

Collating the voice of people with autoimmune diseases: Methodology for the Third Phase of the COVAD Studies

Contemporary medical practice now recognizes the significance of clinical and biological factors and social, demographic, economic, and psychological factors in influencing disease activity and outcomes. Besides treatment based on an understanding …

verfasst von:: Esha Kadam, Mahnoor Javaid, Parikshit Sen, Sreoshy Saha, Nelly Ziade, Jessica Day, Chris Wincup, Laura Andreoli, Ioannis Parodis, Ai Lyn Tan, Samuel Katsuyuki Shinjo, Dzifa Dey, Lorenzo Cavagna, Tulika Chatterjee, Johannes Knitza, Guochun Wang, Nicola Dalbeth, Tsvetelina Velikova, Simone Battista, Karen Cheng, Peter Boyd, Linda Kobert, Abraham Edgar Gracia-Ramos, Srijan Mittal, Ashima Makol, Carlos Enrique Toro Gutiérrez, Carlo V Caballero Uribe, Masataka Kuwana, Gerd-Rüdiger Burmester, Francis Guillemin, Elena Nikiphorou, Hector Chinoy, Vikas Aggarwal, Latika Gupta, the COVAD Study Group

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Open Access 12.04.2024 | Review

Pain catastrophizing in rheumatic diseases: prevalence, origin, and implications

Pain is a crucial factor in rheumatic disorders, and reducing it is a primary goal of successful treatment. Adaptive pain-coping strategies can enhance this improvement, but maladaptive approaches such as pain catastrophizing may worsen overall …

verfasst von:: Mateusz Wilk, Olena Zimba, Glenn Haugeberg, Mariusz Korkosz

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Open Access 11.04.2024 | Patient Opinion

Evaluation of a hybrid telehealth care pathway for patients with axial spondyloarthritis including self-sampling at home: results of a longitudinal proof-of-concept mixed-methods study (TeleSpactive)

Patients with axial spondyloarthritis (axSpA) require close monitoring to achieve the goal of sustained disease remission. Telehealth can facilitate continuous care while relieving scarce healthcare resources. In a mixed-methods proof-of-concept …

verfasst von:: Hannah Labinsky, Susann May, Katharina Boy, Sophie von Rohr, Manuel Grahammer, Sebastian Kuhn, Jessica Rojas-Restrepo, Ekaterina Vogt, Martin Heinze, Georg Schett, Felix Muehlensiepen, Johannes Knitza

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10.04.2024 | Observational Research

Disease activity and widespread pain are main contributors to patient-reported global health in axial spondyloarthritis: an analysis of 6064 patients

Global health (GH) and health-related quality of life are patient priorities in axial spondyloarthritis (axSpA). Our objective was to assess the relative importance of disease-related factors including disease activity, and patient-related factors …

verfasst von:: Juliette Drouet, Clementina López-Medina, Benjamin Granger, Bruno Fautrel, Robert B. M. Landewe, Anna Molto, Cécile Gaujoux-Viala, Uta Kiltz, Maxime Dougados, Laure Gossec

08.04.2024 | Review

Diagnostic delays in systemic vasculitides

Systemic vasculitides are among the less common disorders encountered in routine rheumatology practice. The low incidence and heterogeneous presentation at onset can potentially lead to delayed diagnosis. Not recognizing these in the early phase …

verfasst von:: Akerke Auanassova, Marlen Yessirkepov, Olena Zimba, Sakir Ahmed, Prakashini Mruthyunjaya

Open Access 06.04.2024 | Observational Research

Effects of sporadic inclusion body myositis on skeletal muscle fibre type specific morphology and markers of regeneration and inflammation

Sporadic inclusion body myositis (sIBM) is a subgroup of idiopathic inflammatory myopathies characterised by progressive muscle weakness and skeletal muscle inflammation. Quantitative data on the myofibre morphology in sIBM remains scarce.

verfasst von:: Kasper Yde Jensen, Jakob Lindberg Nielsen, Per Aagaard, Mikkel Jacobsen, Anders Nørkær Jørgensen, Rune Dueholm Bech, Ulrik Frandsen, Louise Pyndt Diederichsen, Henrik Daa Schrøder

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Open Access 06.04.2024 | Observational Research

Cardiovascular safety of using non-steroidal anti-inflammatory drugs for gout: a Danish nationwide case-crossover study

Gout attacks are treated with uric-lowering and anti-inflammatory drugs. In patients with gout, non-steroidal anti-inflammatory drugs (NSAIDs) could be both cardiovascular beneficial, due to their anti-inflammatory actions, and cardiovascular …

verfasst von:: Anne Bech-Drewes, Kasper Bonnesen, Ellen-Magrethe Hauge, Morten Schmidt

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Open Access 05.04.2024 | Expert Opinion

Borrelia burgdorferi and autoimmune mechanisms: implications for mimicry, misdiagnosis, and mismanagement in Lyme disease and autoimmune disorders

The genus Borrelia encompasses a diverse group of spirochetes transmitted primarily by ticks, with Borrelia burgdorferi causing Lyme disease, which is prevalent in North America and Europe. Borrelia’s structural adaptations and ability to persist …

verfasst von:: Bohdana Doskaliuk, Olena Zimba

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Open Access 02.04.2024 | Patient Opinion

Sociodemographic and clinical variables associated with negative illness perception in patients newly diagnosed with rheumatoid arthritis, axial spondyloarthritis, or psoriatic arthritis—a survey based cross-sectional study

When newly diagnosed with inflammatory arthritis (IA), acquiring self-management skills is beneficial, to enhance quality of life. The personal beliefs and mental representations patients hold about their illness, known as illness perception …

verfasst von:: Luise Holberg Lindgren, Annette de Thurah, Tanja Thomsen, Merete Lund Hetland, Mette Aadahl, Sofie Bech Vestergaard, Sara Danshøj Kristensen, Bente Appel Esbensen

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Open Access 02.04.2024 | Observational Research

Pregnancies in patients with systemic lupus erythematosus during 2000–2018 in Finland: a case–control study

The onset of systemic lupus erythematosus (SLE) is often during patients’ reproductive years, and pregnancies in female SLE patients are common. Therefore, many potential threats exist regarding family planning. Of particular concern is active …

verfasst von:: Pia Elfving, Simo Kariniemi, Hannu Kautiainen, Vappu Rantalaiho, Lauri J. Virta, Kari Puolakka, Merja K. Laine

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30.03.2024 | Observational Research

Diagnostic and prognostic role of serum interleukin-6 and carotid ultrasonography to detect subclinical atherosclerosis in patients with RA and ANCA-associated vasculitis

ANCA-associated vasculitis (AAV) can affect multiple organs with severe life-threatening manifestations. Disease monitoring is difficult due to a lack of defined biomarkers. We aimed to assess the diagnostic role of serum interleukin-6 and …

verfasst von:: Velichka Popova, Mariela Geneva-Popova, Stanislava Popova-Belova, Mladen Doykov, Stanislav Valkanov, Zguro Batalov, Aleksandar Marinkov, Rositsa Karalilova

29.03.2024 | Observational Research

Outcomes of COVID-19 re-infections: a single-center cohort of 167 patients with systemic rheumatic diseases

Data on COVID-19 re-infections in patients with systemic rheumatic diseases (SRDs) are lacking. We aimed to describe the course and outcomes of COVID-19 re-infections in these patients versus controls. In this single-center retrospective study, we …

verfasst von:: Alexandros Panagiotopoulos, George E. Fragoulis, Aikaterini Arida, Vassiliki-Kalliopi Bournia, Gerasimos Evangelatos, Kalliopi Fragkiadaki, Evrydiki Kravvariti, Katerina Laskari, Maria Mylona, Nikolaos Michalakeas, Nikolaos Papazoglou, Maria Pappa, Vassiliki Poulia, Stylianos Panopoulos, Sevastiani Ziarangali, Vasileios Papatheodorou, Maria G. Tektonidou, Petros P. Sfikakis

Springer Medizin