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Heart and Vessels OnlineFirst articles

Open Access 07.06.2023 | Original Article

Association of preoperative clinical frailty and clinical outcomes in elderly patients with stable coronary artery disease after percutaneous coronary intervention

There are few reports on the long-term clinical outcome after percutaneous coronary intervention (PCI) in patients with stable coronary artery disease (CAD) complicated with frailty. This novel study investigated the association between pre-PCI …

verfasst von:
Hirokazu Shimono, Akihiro Tokushige, Daisuke Kanda, Ayaka Ohno, Masao Hayashi, Mana Fukuyado, Mitsumasa Akao, Mariko Kawasoe, Ryo Arikawa, Hideaki Otsuji, Hideto Chaen, Hideki Okui, Naoya Oketani, Mitsuru Ohishi

06.06.2023 | Original Article

Prognostic impact of a reduction in the fibrosis-4 index among patients hospitalized with acute heart failure

Although the fibrosis-4 index (FIB-4) is associated with right atrial pressure or prognosis in acute heart failure (AHF), the prognostic impact of its reduction during hospitalization remains uncertain. We included 877 patients (age, 74.9 ± 12.0 …

verfasst von:
Daichi Maeda, Yumiko Kanzaki, Kazushi Sakane, Kosuke Tsuda, Kanako Akamatsu, Ryoto Hourai, Takahiro Okuno, Daisuke Tokura, Hitomi T. Hasegawa, Hideaki Morita, Takahide Ito, Masaaki Hoshiga

01.06.2023 | Original Article

Perspectives of hospitalized heart failure patients: preferred and perceived participation roles in treatment decisions

Shared decision-making (SDM) is a pivotal process in seeking optimal individual treatment and incorporating clinical evidence and patients’ autonomous preferences. However, patients’ actual attitudes toward participation in decision-making for …

verfasst von:
Otoya Sekine, Hiroki Kitakata, Shun Kohsaka, Daisuke Fujisawa, Naomi Nakano, Yasuyuki Shiraishi, Yoshikazu Kishino, Yoshinori Katsumata, Shinsuke Yuasa, Keiichi Fukuda, Takashi Kohno

29.05.2023 | Original Article

Clinical outcome of endovascular therapy using a VIABAHN VBX-covered stent for complex aortoiliac artery disease: the AVOCADO II study

Clinical trials have demonstrated the efficacy of a balloon-expandable covered stent (CS) for aortoiliac occlusive disease (AIOD). However, the real-world clinical outcomes and the underlying factors remain unclear. We assessed the clinical …

verfasst von:
Yusuke Tomoi, Mitsuyoshi Takahara, Yoshimitsu Soga, Yosuke Hata, Osamu Iida, Terutoshi Yamaoka, Naoki Hayakawa, Masahiko Fujihara, Kenji Ando, On behalf of ADOCADO II Investigators

23.05.2023 | Original Article

Multicenter, retrospective registry of isolated atherosclerotic popliteal arteries treated with endovascular revascularization

Isolated atherosclerotic popliteal lesions (IAPLs) have been considered challenging. This study aimed to investigate the efficacy of endovascular therapy (EVT) using the newer devices for IAPLs. This retrospective multicenter registry analyzed …

verfasst von:
Kazunori Horie, Mitsuyoshi Takahara, Tatsuya Nakama, Akiko Tanaka, Kazuki Tobita, Naoki Hayakawa, Shinsuke Mori, Yo Iwata, Kenji Suzuki

18.05.2023 | Original Article

Feasibility of rotational atherectomy in patients with acute coronary syndrome: favorable in-hospital outcomes and clinical importance of complexed coronary atherosclerosis

The feasibility of rotational atherectomy (RA) during percutaneous coronary intervention (PCI) in patients who present with acute coronary syndrome (ACS) remains fully unsettled. We retrospectively evaluated 198 consecutive patients who underwent …

verfasst von:
Shuichi Yoneda, Yasuhide Asaumi, Kota Murai, Takamasa Iwai, Hideo Matama, Kenichiro Sawada, Hiroyuki Miura, Satoshi Honda, Masashi Fujino, Kensuke Takagi, Fumiyuki Otsuka, Yu Kataoka, Kunihiro Nishimura, Teruo Noguchi

Open Access 23.04.2023 | Original Article

Prognostic value of the liver fibrosis marker fibrosis-5 index in patients with severe isolated tricuspid regurgitation: comparison with fibrosis-4 index

The fibrosis-4 index (FIB4), a liver fibrosis maker, has been shown to be associated with the prognosis in patients with severe isolated tricuspid regurgitation (TR). Recent study showed that the fibrosis-5 index (FIB5), which was calculated by …

verfasst von:
Mitsutaka Nakashima, Toru Miyoshi, Machiko Tanakaya, Takaaki Saito, Yusuke Katayama, Satoru Sakuragi, Yoichi Takaya, Hiroshi Ito

20.04.2023 | Original Article

Clinical and prognostic implications of hyaluronic acid in hospitalized patients with heart failure

We investigated the clinical and prognostic implications of hyaluronic acid, a liver fibrosis marker, in patients with heart failure. We measured hyaluronic acid levels on admission in 655 hospitalized patients with heart failure between January …

verfasst von:
Daichi Maeda, Yuya Matsue, Taishi Dotare, Tsutomu Sunayama, Takashi Iso, Shoichiro Yatsu, Sayaki Ishiwata, Yutaka Nakamura, Yuka Akama, Yuichiro Tsujimura, Shoko Suda, Takao Kato, Masaru Hiki, Takatoshi Kasai, Tohru Minamino

19.04.2023 | Original Article

Mean pulmonary artery pressure estimated by echocardiogram rapidly exceeds 20 mmHg from the normal range in patients with connective tissue disease

Earlier intervention for pulmonary hypertension (PH) has been reported to improve the prognosis of patients with connective tissue disease (CTD). However, it is not fully elucidated how rapidly PH develops in patients showing normal mean pulmonary …

verfasst von:
Yoshiyuki Orihara, Masanori Asakura, Kyung-Duk Min, Yuki Matsumoto, Isamu Sunayama, Koichi Nishimura, Akiyo Eguchi, Yoshitaka Okuhara, Masaharu Ishihara

Open Access 17.04.2023 | Original Article

Prognostic impact of fractional flow reserve measurements in patients with acute coronary syndromes: a subanalysis of the FLORIDA study

Randomized trials suggest benefits for fractional flow reserve (FFR)-guided vs. angiography-guided treatment strategies in well-defined and selected patient cohorts with acute coronary syndromes (ACS). The long-term prognostic value of FFR …

verfasst von:
Teresa Gerhardt, Barbara E. Stähli, Tanja K. Rudolph, Matthias Lutz, Anne-Sophie Schatz, Lukas Zanders, Tino Schubert, Magnus Stueve, Nick E. J. West, Els Boone, Ulf Landmesser, David M. Leistner

Open Access 13.04.2023 | Original Article

Association between complete revascularization of the coronary artery and clinical outcomes in peripheral artery disease: a sub-analysis of the I-PAD Nagano registry

Peripheral artery disease (PAD) is commonly caused by atherosclerosis and has an unfavorable prognosis. Complete revascularization (CR) of the coronary artery reduces the risk of major adverse cardiovascular event (MACE) in patients with coronary …

verfasst von:
Tamon Kato, Yasushi Ueki, Masatoshi Minamisawa, Takashi Miura, Yushi Oyama, Naoto Hashizume, Daisuke Yokota, Minami Taki, Keisuke Senda, Yoshiteru Okina, Tadamasa Wakabayashi, Koki Fujimori, Kenichi Karube, Takahiro Sakai, Hidetomo Nomi, Hisanori Yui, Yusuke Kanzaki, Keisuke Machida, Shusaku Maruyama, Ayumu Nagae, Tatsuya Saigusa, Soichiro Ebisawa, Ayako Okada, Hirohiko Motoki, Koichiro Kuwahara, the I-PAD investigators

11.04.2023 | Original Article

Age and sex differences in the risk of cardiovascular diseases by chronic kidney disease in a general Japanese population

The risk of cardiovascular diseases (CVD) by chronic kidney disease (CKD) stratified by age and sex has not been examined in detail in rural Japanese populations. Therefore, we herein investigated the long-term risk of CVD by CKD and performed an …

verfasst von:
Yuko Ago Shiraishi, Yukiko Ishikawa, Joji Ishikawa, Masami Matsumura, Shizukiyo Ishikawa

07.04.2023 | Original Article

Prediction of spontaneous echocardiographic contrast within the left atrial appendage in cardiac computed tomography of patients with atrial fibrillation

This study aimed to assess the predictors of spontaneous echocardiographic contrast (SEC) using left atrial appendage (LAA) findings in cardiac computed tomography (CT) of patients with atrial fibrillation (AF). We retrospectively analyzed cardiac …

verfasst von:
Kotaro Ouchi, Toru Sakuma, Takahiro Higuchi, Jun Yoshida, Ryosuke Narui, Ayumi Nojiri, Teiichi Yamane, Hiroya Ojiri

07.04.2023 | Original Article

Progression from paroxysmal to persistent atrial fibrillation in pacemaker patients with tachycardia–bradycardia syndrome: a multicenter study

Progression from paroxysmal to persistent atrial fibrillation (AF) is occasionally encountered in patients with previous pacemaker implantation (PMI) for the treatment of tachycardia–bradycardia syndrome (TBS). We aimed to determine the rate of …

verfasst von:
Naoto Oguri, Akinori Sairaku, Nobuyuki Morishima, Yasuhiko Hayashi, Yuji Muraoka, Shunsuke Tomomori, Takenori Okada, Yukiko Nakano

Open Access 01.04.2023 | Original Article

MELD-score for risk stratification in cardiac surgery

The outcome of the patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) is also influenced by the renal and hepatic organ functions. Risk stratification, using scores such as EURO Score II or STS Short-Term Risk Calculator for …

verfasst von:
Presheet Pathare, Mohamed Elbayomi, Michael Weyand, Colin Griesbach, Frank Harig

01.04.2023 | Original Article

The reliability and utility of on-site CT-derived fractional flow reserve (FFR) based on fluid structure interactions: comparison with FFRCT based on computational fluid dynamics, invasive FFR, and resting full-cycle ratio

Fractional flow reserve (FFR) derived off-site by coronary computed tomography angiography (CCTA) (FFRCT) is obtained by applying the principles of computational fluid dynamics. This study aimed to validate the overall reliability of on-site …

verfasst von:
Yuto Fujii, Toshiro Kitagawa, Hiroki Ikenaga, Fuminari Tatsugami, Kazuo Awai, Yukiko Nakano

Open Access 30.03.2023 | Original Article

Predictors of physical frailty improvement in older patients enrolled in a multidisciplinary cardiac rehabilitation program

Cardiac rehabilitation (CR) improves clinical and functional recovery in older patients after acute cardiac syndromes, whose outcome is influenced by cardiac disease severity, but also by comorbidity and frailty. The aim of the study was to …

verfasst von:
Samuele Baldasseroni, Maria Vittoria Silverii, Andrea Herbst, Francesco Orso, Mauro Di Bari, Alessandra Pratesi, Costanza Burgisser, Andrea Ungar, Niccolò Marchionni, Francesco Fattirolli

28.03.2023 | Original Article

Acute coronary syndrome in very elderly patients—a real-world experience

Very elderly population constitutes an increasingly larger proportion of patients admitted for acute coronary syndromes (ACS). Notably, age represents both a proxy of frailty and an exclusion criterion in clinical randomized trials, which probably …

verfasst von:
Matteo Bianco, Filiberto Fausto Mottola, Enrico Cerrato, Francesca Giordana, Sebastian Cinconze, Giorgio Baralis, Alison Verra, Giuseppe Musumeci, Roberta Rossini

Open Access 21.03.2023 | Original Article

Clinical outcomes after coronary artery bypass grafting in patients with dialysis-dependent end-stage renal disease and an analysis of the related influencing factors

Perioperative and short/mid-term survival rates of dialysis-dependent patients with end-stage renal disease (ESRD), who undergo coronary artery bypass grafting (CABG), and the factors influencing mortality are not well evaluated In China. We …

verfasst von:
Xi-hui Li, Si-yu Zhang, Feng Xiao

18.03.2023 | Original Article

Age- and sex-stratified normal values for circulatory and ventilatory power during ramp exercise derived from a healthy Japanese population

Circulatory power (CP) and ventilatory power (VP), obtained by cardiopulmonary exercise testing (CPX), have been suggested to be excellent prognostic markers for heart failure. However, the normal values of these parameters in healthy Japanese …

verfasst von:
Kohei Ashikaga, Haruki Itoh, Tomoko Maeda, Yuri Ichikawa, Shiori Tanaka, Akira Koike, Shigeru Makita, Kazuto Omiya, Yuko Kato, Hitoshi Adachi, Masatoshi Nagayama, Yoshihiro J. Akashi, on behalf of the Committee on Exercise Prescription for Patients (CEPP) Members