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Neurology and Therapy OnlineFirst articles

Open Access 26.03.2024 | ORIGINAL RESEARCH

REBISTART: Adherence of Patients with Multiple Sclerosis to Treatment with Subcutaneous Interferon Beta in the Context of a Patient Support Program

Adherence to prescribed drug therapy is a critical prerequisite in the management of chronic diseases [ 1 , 2 ]. Poor adherence negatively affects outcomes and health benefits of pharmacological treatments [ 3 ]. Adherence is influenced by dosing …

verfasst von:
Matthias Schwab, Andrew Chan, Anna-Katharina Eser, Boris Kallmann, Dieter Pöhlau, Joachim Richter, Torsten B. Wagner, Christoph Grothe

Open Access 26.03.2024 | CASE SERIES

Anti-N-methyl-d-aspartate Receptor Encephalitis in People Living with HIV: Case Report and Literature Review

With the increase in the number of cases of autoimmune encephalitis (AE), the cerebrospinal fluid (CSF) of people living with HIV (PLWH) showing abnormal behavior, cognitive impairment or abnormal movements should be actively screened for the …

verfasst von:
Jiangjin Hui, Jinhua Wang, Zhikai Wan, Qing Cao, Bohao Dai, Haiyan Lou, Biao Zhu

Open Access 21.03.2024 | ORIGINAL RESEARCH

Impact of Baseline Neuropathy Severity on Vutrisiran Treatment Response in the Phase 3 HELIOS-A Study

Hereditary transthyretin (ATTRv, v for variant) amyloidosis, also known as hATTR amyloidosis, is a rare, progressive, debilitating, and fatal disease caused by variants in the transthyretin ( TTR ) gene [ 1 – 4 ]. Pathogenic TTR variants lead to …

verfasst von:
Marco Luigetti, Dianna Quan, John L. Berk, Isabel Conceição, Yohei Misumi, Chi-Chao Chao, Shaun Bender, Emre Aldinc, John Vest, David Adams

Open Access 19.03.2024 | Publisher Correction

Publisher Correction: Summary of Research: What Is the True Impact of Cognitive Impairment for People Living with Multiple Sclerosis? A Commentary of Symposium Discussions at the 2020 European Charcot Foundation

verfasst von:
Sarah A. Morrow, Paola Kruger, Dawn Langdon, Nektaria Alexandri

Open Access 18.03.2024 | Correction

Correction: Neurofilament Light Chain in Adult and Pediatric Multiple Sclerosis: A Promising Biomarker to Better Characterize Disease Activity and Personalize MS Treatment

Monreal E, Fernández-Velasco J, García-Sánchez MI, et al. Association of serum neurofilament light chain levels at disease onset with disability worsening in patients with a first demyelinating multiple sclerosis event not treated with …

verfasst von:
Angelo Ghezzi, R. F. Neuteboom

Open Access 15.03.2024 | REVIEW

Holistic, Long-Term Management of People with Relapsing Multiple Sclerosis with Cladribine Tablets: Expert Opinion from France

Cladribine tablets (CladT) has been available for therapeutic use in France since March 2021 for the management of highly active relapsing multiple sclerosis (RMS). This high-efficacy disease-modifying therapy (DMT) acts as an immune …

verfasst von:
Jonathan Ciron, Bertrand Bourre, Giovanni Castelnovo, Anne Marie Guennoc, Jérôme De Sèze, Ali Frederic Ben-Amor, Carine Savarin, Patrick Vermersch

Open Access 07.03.2024 | ORIGINAL RESEARCH

Assessing the Long-Term (48-Week) Effectiveness, Safety, and Tolerability of Fremanezumab in Migraine in Real Life: Insights from the Multicenter, Prospective, FRIEND3 Study

Migraine is a progressive neurological disorder that may evolve into a chronic form if left untreated or improperly treated [ 1 ]. Adequate prophylactic treatment, recommended for patients with at least 3–4 disabling migraine days per month, should …

verfasst von:
Piero Barbanti, Gabriella Egeo, Stefania Proietti, Florindo d’Onofrio, Cinzia Aurilia, Cinzia Finocchi, Laura Di Clemente, Maurizio Zucco, Alberto Doretti, Stefano Messina, Massimo Autunno, Angelo Ranieri, Antonio Carnevale, Bruno Colombo, Massimo Filippi, Miriam Tasillo, Steno Rinalduzzi, Pietro Querzani, Giuliano Sette, Lorenzo Forino, Francesco Zoroddu, Micaela Robotti, Alessandro Valenza, Cecilia Camarda, Laura Borrello, Marco Aguggia, Giovanna Viticchi, Carlo Tomino, Giulia Fiorentini, Bianca Orlando, Stefano Bonassi, Paola Torelli, for the Italian Migraine Registry study group

Open Access 06.03.2024 | ORIGINAL RESEARCH

Impact of Immune Cells on Stroke Limited to Specific Subtypes: Evidence from Mendelian Randomization Study

Stroke is one of the common diseases that pose a severe threat to human health. Globally, approximately 16 million people suffer from acute stroke each year, ranking it as the second leading cause of death [ 1 ]. Stroke has a high disability and …

verfasst von:
Chen Chen, Qi Liu, Yao Li, Jingwen Yu, Shudi Wang, Li Liu

Open Access 02.03.2024 | ORIGINAL RESEARCH

Assessment of Barriers to Referral and Appointment Wait Times for the Evaluation of Spinal Muscular Atrophy (SMA): Findings from a Web-Based Physician Survey

verfasst von:
Mary A. Curry, Rosángel E. Cruz, Lisa T. Belter, Mary K. Schroth, Jill Jarecki

Open Access 01.03.2024 | ORIGINAL RESEARCH

Constructing and Validating a Nomogram Model for Short-Term Prognosis of Patients with AChR-Ab+ GMG

Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fluctuating muscle weakness and fatigability [ 1 , 2 ]. It occurs when antibodies attack and disrupt the communication between nerves and muscles at the neuromuscular …

verfasst von:
Feng Liang, Zhaoxu Yin, Yaqian Li, Guanxi Li, Jing Ma, Huiqiu Zhang, Xiaoqian Xia, Make Yao, Xiaomin Pang, Juan Wang, Xueli Chang, Junhong Guo, Wei Zhang

Open Access 01.03.2024 | ORIGINAL RESEARCH

The Association Between National Institutes of Health Stroke Scale Score and Clinical Outcome in Patients with Large Core Infarctions Undergoing Endovascular Treatment

Endovascular therapy (EVT) has been shown to significantly improve prognosis and reduce mortality rates compared to standard drug therapy in cases of anterior circulation large vessel occlusion with small core infarctions and large ischemic …

verfasst von:
Lingyu Zhang, Jinfu Ma, Mengmeng Wang, Lin Zhang, Wenzhe Sun, Honghong Ji, Chengsong Yue, Jiacheng Huang, Wenjie Zi, Fengli Li, Changwei Guo, Pengfei Wang

Open Access 20.02.2024 | SUMMARY OF RESEARCH

Summary of Research: What Is the True Impact of Cognitive Impairment for People Living with Multiple Sclerosis? A Commentary of Symposium Discussions at the 2020 European Charcot Foundation

Cognitive symptoms affect disease management and activities of daily living for people living with multiple sclerosis (MS). This summary of research article summarises previously published discussions (‘What is the true impact of cognitive …

verfasst von:
Sarah A. Morrow, Paola Kruger, Dawn Langdon, Nektaria Alexandri