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Graefe's Archive for Clinical and Experimental Ophthalmology OnlineFirst articles

20.02.2024 | Retinal Disorders

Changes in wider field swept-source OCT angiography vascular metrics with anti-vascular endothelial growth factor therapy in central retinal vein occlusion

Retinal vein occlusion (RVO) is an important cause of vision loss affecting around 28 million people worldwide [ 1 ]. Anatomically, it can be classified into central RVO (CRVO) and branch RVO (BRVO) based on the extent of the obstruction. CRVO …

verfasst von:
Peyman Razavi, Grace Baldwin, Itika Garg, Luis Martinez Velazquez, Mauricio Garcia, Jenny Gan, Hanna Choi, Rebecca Zeng, Filippos Vingopoulos, Deeba Husain, Leo A. Kim, Nimesh A. Patel, John B. Miller

20.02.2024 | Refractive Surgery

Predictability comparison of sizing parameters for postoperative vault after implantable Collamer lens implantation

The Implantable Collamer Lens (ICL) is a widely used posterior chamber phakic intraocular lens known for its excellent long-term safety, effectiveness, and predictability [ 1 ]. The success of ICL implantation depends on the postoperative vault …

verfasst von:
Jun Zhu, Fen-Fen Li, Shang-Yang Jiang, Dan Cheng, Guan-Shun Yu, Xue-Ying Zhu, Fang-Jun Bao, Shuang-Qing Wu, Qi Dai, Yu-Feng Ye

19.02.2024 | Refractive Surgery

Analysis on the changes of objective indicators of dry eye after implantable collamer lens (ICL) implantation surgery

The implantable collamer lens (ICL) has good safety, efficacy, stability, and predictability in the correction of myopia, hyperopia, and astigmatism. In addition, the ICL has the advantages of reversibility, wide range of correction, and stable …

verfasst von:
Hao Zhang, Yingping Deng, Ke Ma, Hongbo Yin, Jing Tang

19.02.2024 | Glaucoma

Aqueous misdirection syndrome: clinical outcomes and risk factors for treatment failure

Aqueous misdirection (AM) commonly referred to as malignant glaucoma is a rare and serious form of secondary glaucoma described since 1869 [ 1 – 4 ]. In aqueous misdirection, there is posterior misdirection of aqueous into the vitreous cavity with …

verfasst von:
Sirisha Senthil, Shaveta Goyal, Ashik Mohamed, Chandrasekhar Garudadri

17.02.2024 | Retinal Disorders

Morphological characteristics of the foveal avascular zone in pathological myopia and its relationship with macular structure and microcirculation

The prevalence of myopia, one of the most common blind eye diseases worldwide, has significantly increased in recent decades. It is estimated that by 2050, the global population with myopia and high myopia will reach 5 billion and 1 billion …

verfasst von:
Jinyuan Sui, Haoru Li, Yang Bai, Qing He, Ziwen Sun, Ruihua Wei

Open Access 16.02.2024 | Pediatrics

Postoperative outcome and influencing factors of strabismus surgery in infants aged 1–6 years

Strabismus is defined as a common ocular misalignment among children with a prevalence of 3–5% [ 1 ]. Surgical treatment remains a challenge since the surgical protocols are not standardized and there is still a lack of studies comparing surgical …

verfasst von:
Laetitia Hinterhuber, Sandra Rezar-Dreindl, Ursula Schmidt-Erfurth, Eva Stifter

Open Access 16.02.2024 | Inflammatory Disorders

Outcomes of pars plana vitrectomy in the management and diagnosis of patients with infectious, non-infectious, and unidentified uveitis

Uveitis includes various disease entities and creates diagnostic and management challenges. The first step for successful management of uveitis is based on accurate diagnosis and appropriate treatment. Medical treatment remains the mainstay of …

verfasst von:
Hande Celiker, Furkan Çam, Berru Yargı Özkoçak

15.02.2024 | Review Article

Retinal imaging and Alzheimer’s disease: a future powered by Artificial Intelligence

Alzheimer’s disease (AD) is a neurodegenerative condition that primarily affects brain tissue. Because the retina and brain share the same embryonic origin, visual deficits have been reported in AD patients. Artificial Intelligence (AI) has …

verfasst von:
Hamidreza Ashayeri, Ali Jafarizadeh, Milad Yousefi, Fereshteh Farhadi, Alireza Javadzadeh

Open Access 15.02.2024 | Pediatrics

Refractive predictive errors using Barrett II, Hoffer-Q, and SRKT formulae for pediatric IOL implantation

Congenital and childhood cataracts constitute a significant cause of visual disability in children and are responsible for 5–20% of pediatric blindness globally [ 1 ]. When a cataract significantly affects vision or visual development, it is …

verfasst von:
Or Shmueli, Nur Azem, Ana Navarrete, Milka Matanis-Suidan, Ran David, Hadas Mechoulam, Irene Anteby

15.02.2024 | Retinal Disorders

Outcomes of rhegmatogenous retinal detachment surgery in patients with Stickler syndrome

First described in 1965 by Gunnar Stickler, Stickler syndrome (SS) is a heterogeneous inherited disorder of collagen formation that presents with highly variable signs and symptoms. It includes orofacial, musculoskeletal, auditory, and ocular …

verfasst von:
Iñigo Corcóstegui, Javier Subirás, Borja Corcóstegui

14.02.2024 | Oculoplastics and Orbit

Supraperiosteal fat repositioning with midface lift in lower eyelid blepharoplasty: an 18-year experience

Tear trough deformity is a commonly encountered cosmetic concern arising from anatomical alteration of fat pad in the lower eyelid, primarily attributed to the aging process but not exclusively. The underlying anatomical factors include thinning …

verfasst von:
Anny Mansim Cheng, Ann Yi-chiun Chuang, Yi-Hsuan Wei, Sirtaz Singh Sibia, Shu-Lang Liao

13.02.2024 | Cornea

Monitoring the transition from corneal ulceration to healed scar using a Scheimpflug tomography–based densitometry

Corneal opacities have been a worldwide issue and one of the prevalent causes of blindness globally [ 1 ]. Ulcerative keratitis (UK), the leading cause of corneal opacity, can result in permanent visual impairment by destroying the corneal …

verfasst von:
Yen-Cheng Chen, Yu-Ting Hsiao, Shu-Fang Kuo, Hun-Ju Yu, Po-Chiung Fang, Ren-Wen Ho, I-Hui Yang, Ming-Tse Kuo

13.02.2024 | Retinal Disorders

Factors associated with the development of exudation in treatment-naive eyes with nonexudative macular neovascularization

Neovascular age-related macular degeneration (AMD) is the vision-threatening late form of AMD, characterized by the development of macular neovascularization (MNV) [ 1 ]. The onset of MNV in neovascular AMD typically has been defined by the onset …

verfasst von:
Han Joo Cho, Minchul Kim, Jeongmin Kim, Isang Yoon, Sangmin Park, Chul Gu Kim

Open Access 12.02.2024 | Neurophthalmology

Neuro-ophthalmic complications of modern anti-cancer drugs

Modern, targeted cancer drugs have revolutionized the treatment of cancer over the past two decades and contributed to the continued progress in improving cancer survival rates. The field is rapidly expanding with increasing numbers of drugs …

verfasst von:
Joshua A. Oskam, Helen V. Danesh-Meyer

09.02.2024 | Glaucoma

A multi-label transformer-based deep learning approach to predict focal visual field progression

Glaucoma is a heterogeneous group of progressive optic neuropathies that represents the leading cause of irreversible blindness worldwide [ 1 ]. The assessment of the visual field (VF) through standard automated perimetry serves as a quantifiable …

verfasst von:
Ling Chen, Vincent S. Tseng, Ta-Hsin Tsung, Da-Wen Lu

08.02.2024 | Cornea

Predictive factors for re-bubbling after DMEK: focus on the posterior corneal surface

Descemet membrane endothelial keratoplasty (DMEK) has recently become one of the most popular surgical techniques in cases of uncomplicated endothelial decompensation [ 1 ]. While allowing for faster and usually better visual recovery and for …

verfasst von:
Raphael Kilian, Emanuele Crincoli, Jan Lammer, Clara Rizzo, Emilio Pedrotti, Gerald Schmidinger

08.02.2024 | Cataract

Trichromatic critical flicker frequency as potential visual test in cataract and macula disease patients

Cataract, the foremost cause of global blindness, is associated with an increased risk starting from age 40 and progressing with each subsequent decade [ 1 ]. Surgical intervention stands as the most efficacious treatment. The presence of ocular …

verfasst von:
Guangcan Xu, Yu Luo, Haolan Qi, Sijia Liu, Junxia Fu, Zi Ye, Zhaohui Li

Open Access 08.02.2024 | Retinal Disorders

OCT risk factors for 2-year foveal involvement in non-treated eyes with extrafoveal geographic atrophy and AMD

Geographic atrophy (GA) is the non-neovascular form of late age-related macular degeneration (AMD) [ 1 ]. GA is responsible for 10 to 20% of cases of legal blindness in patients with AMD [ 2 ] and it is estimated to affect more than 5 million …

verfasst von:
Enrico Borrelli, Costanza Barresi, Alessandro Berni, Pasquale Viggiano, Michele Reibaldi, Ugo Introini, Francesco Bandello

06.02.2024 | Cataract

Antibiotic susceptibility in Endophthalmitis Management Study and intravitreal antibiotic practice trend in India—EMS Report #5

The Endophthalmitis Management Study (EMS) is a multicentre prospective randomized clinical trial of post cataract surgery endophthalmitis [ 1 ]. Registered in the Clinical Trial Registry of India (CTRI/2019/02/017876), the EMS had two primary …

verfasst von:
Taraprasad Das, Suchita Pandey, Joveeta Joseph, Jay Sheth, Akash Belenje, Umesh C. Behera, Aditya Kapoor, Rudvij Pandya, Vivek Pravin Dave

Open Access 01.02.2024 | Retinal Disorders

Association of triglyceride‑glucose index in branch retinal vein occlusion

Retinal vein occlusion (RVO) leads to notable vision loss and ranks as the second most common vascular ailment affecting the retina. RVO can be classified into two subtypes depending on the site of the obstructed blood vessel: branch retinal vein …

verfasst von:
Hatice Aslan Sirakaya, Ender Sirakaya