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Clinical Neuroradiology OnlineFirst articles

15.08.2019 | Original Article

Safety and Long-term Efficacy of Stent-assisted Coiling for the Treatment of Complex Posterior Cerebral Artery Aneurysms

Complex posterior cerebral artery (PCA) aneurysms refer to those aneurysms that are difficult to cure with simple coil embolization, either owing to the etiology or the morphology. These PCA aneurysms are rare and account for less than 1% of all …

Gaici Xue, Haishuang Tang, Peng Liu, Qiao Zuo, Pengfei Yang, Yu Zhou, Qiang Li, Yibin Fang, Qinghai Huang, Bo Hong, Yi Xu, Rui Zhao, Jianmin Liu

09.08.2019 | Original Article

Associations Between Diffusion Dynamics and Functional Outcome in Acute and Early Subacute Ischemic Stroke

The predictive value of clinical measurements such as age, baseline neurological status, baseline level of C‑reactive protein, and many others, have been assessed for functional outcome of ischemic stroke [ 1 , 2 ]; however, prediction of stroke …

Chengxia Liu, Shun Zhang, Yihao Yao, Changliang Su, Zhenxiong Wang, Minghuan Wang, Wenzhen Zhu

09.08.2019 | Original Article

The p64 Flow Diverter—Mid-term and Long-term Results from a Single Center

Flow diversion has become a widely accepted therapeutic option for the treatment of intracranial aneurysms particularly in the setting of challenging anatomical features, such as wide-neck side wall configuration, complex fusiform morphology …

S. Sirakov, A. Sirakov, P. Bhogal, M. Penkov, K. Minkin, K. Ninov, H. Hristov, V. Karakostov, R. Raychev

08.08.2019 | Original Article

Assessment of Melanin Content and its Influence on Susceptibility Contrast in Melanoma Metastases

Among all primary neoplasms in adults, melanomas have the highest propensity to metastasize to the brain [ 1 ] and it has been shown that high melanin levels in melanoma lesions attenuate the response to chemotherapy and radiotherapy [ 2 ].

Sina Straub, Frederik B. Laun, Martin T. Freitag, Christian Kölsche, Andreas von Deimling, Michael Denoix, Martin Bendszus, Heinz-Peter Schlemmer, Mark E. Ladd, Till M. Schneider

08.08.2019 | Information


08.08.2019 | Correspondence

Cerebral Corticoarterial Malformations

A Case Series of Unilateral Polymicrogyria and Ipsilateral Arterial Dysplasia

Development of the cerebral cortex and its vasculature occurs as a coordinated, codependent process, tightly controlled by robust genetic algorithms [ 1 , 2 ]. Advances in medical imaging are providing phenotypic examples where aberrancy in the …

Jesse M. Klostranec, Waleed Brinjikji, Shobhit Mathur, Emanuele Orru, Danielle M. Andrade, Timo Krings

07.08.2019 | Editorial

Stability Accomplished …

László Solymosi

06.08.2019 | Original Article

Vessel Wall and Lumen Features in North American Moyamoya Patients

Moyamoya disease is characterized by idiopathic progressive narrowing of the supraclinoid internal carotid arteries (ICAs) with development of collateral vessels [ 1 , 2 ]. A similar vascular phenotype is seen in moyamoya syndrome, which arises …

Petrice M. Cogswell, Sarah K. Lants, L. Taylor Davis, Meher R. Juttukonda, Matthew R. Fusco, Manus J. Donahue

06.08.2019 | Clinical Case

Freiburg Neuropathology Case Conference

Hypersalivatory Seizures in a 6-year-old Child

A 6-year-old girl had suffered from refractory epilepsy with hypersalivatory seizures for 2 years. She showed no neurological deficits and development was normal. Non-invasive evaluation with magnetic resonance imaging (MRI) revealed a lesion in …

C. A. Taschner, R. Sankowski, C. Scheiwe, H. Urbach, C. Storz, M. Prinz

02.08.2019 | Original Article

Differential Benefit of Collaterals for Stroke Patients Treated with Thrombolysis or Supportive Care

A Propensity Score Matched Analysis

Collateral blood supply plays an important role in the pathophysiology of acute ischemic stroke [ 1 , 2 ]. The arterial collateralization consists of primary collaterals from the circle of Willis and secondary collaterals via leptomeningeal or …

Felix Schuler, Lukas T. Rotkopf, Daniel Apel, Matthias P. Fabritius, Steffen Tiedt, Frank A. Wollenweber, Lars Kellert, Franziska Dorn, Thomas Liebig, Kolja M. Thierfelder, Wolfgang G. Kunz

02.08.2019 | Original Article

Optimized Combination of b‑values for IVIM Perfusion Imaging in Acute Ischemic Stroke Patients

Intravoxel incoherent motion (IVIM) is a magnetic resonance imaging (MRI) perfusion technique that does not require the injection of a contrast agent [ 1 ]. It derives perfusion parameters from diffusion-weighted imaging (DWI) with multiple …

Guangming Zhu, Jeremy J. Heit, Blake W. Martin, David G. Marcellus, Christian Federau, Max Wintermark

26.07.2019 | Original Article

Age-related Brain Metabolic Changes up to Seventh Decade in Healthy Humans

Whole-brain Magnetic Resonance Spectroscopic Imaging Study

Knowledge of brain metabolic changes under normal aging is a prerequisite for identification of pathological metabolic alterations caused by neurodegenerative processes. Proton magnetic resonance spectroscopy ( 1 H-MRS) detectable brain …

Helen Maghsudi, Martin Schütze, Andrew A. Maudsley, Mete Dadak, Heinrich Lanfermann, Xiao-Qi Ding

23.07.2019 | Original Article

Efficacy and Safety of Mechanical Thrombectomy for Occlusion of the Second Segment of the Middle Cerebral Artery

Retrospective Analysis of the Tama-REgistry of Acute endovascular Thrombectomy (TREAT)

There has been significant progress in the endovascular treatment of large vessel occlusion (LVO) in the past few decades. Since the publication of 5 randomized controlled trials (RCT) in 2015 that reported the efficacy of acute thrombectomy in …

Tomoyuki Nakano, Keigo Shigeta, Takahiro Ota, Tatsuo Amano, Masayuki Ueda, Yuji Matsumaru, Yoshiaki Shiokawa, Teruyuki Hirano

19.07.2019 | Correspondence

Direct Puncture of the Cavernous Sinus as Alternative Approach to Treat a Dural Arteriovenous Fistula of the Hypoglossal Canal

A 57-year-old man presented with a 2-month history of left eye proptosis, third nerve paresis, and conjunctival hyperemia. Magnetic resonance imaging (MRI) revealed a venous pouch within the left hypoglossal canal and dilatation of the superior …

Johnni Zamponi Júnior, Felipe Padovani Trivelato, Alexandre Cordeiro Ulhôa, Marco Túlio Rezende

15.07.2019 | Original Article

Preliminary Experience with Cangrelor for Endovascular Treatment of Challenging Intracranial Aneurysms

Antiplatelet therapy is a key medication for stent-assisted coiling or flow-diversion treatment of intracranial aneurysms [ 1 , 2 ]. During the first months after stent deployment, in order to avoid (or a least reduce) the risk of thromboembolic …

Lamine Abdennour, Nader Sourour, Mehdi Drir, Kévin Premat, Eimad Shotar, Guillaume Taylor, Anne Godier, Jugurtha Mathout, Stéphanie Lenck, Remy Bernard, Alexandre Carpentier, Vincent Degos, Frédéric Clarençon

09.07.2019 | Letter to the Editor

Neuroimaging of Intracranial Perfusion and the Clinical Diagnosis of Brain Death: Setting the Gold Standard in Humans

Mohamed Y. Rady

09.07.2019 | Letter to the Editor

Reply to Letter to the Editor “Neuroimaging of Intracranial Perfusion and the Clinical Diagnosis of Brain Death: Setting the Gold Standard in Humans”

M. Sawicki, J. Sołek-Pastuszka, K. Chamier-Ciemińska, A. Walecka, J. Walecki, R. Bohatyrewicz

26.06.2019 | Original Article Open Access

Noninvasive Differentiation of Meningiomas and Dural Metastases Using Intratumoral Vascularity Obtained by Arterial Spin Labeling

Meningiomas are the most common primary intracranial tumors in adults, representing approximately one third of all intracranial neoplasms [ 1 , 2 ]. They arise from meningothelial cells of the arachnoid and present as avid, homogeneous …

Julia Furtner, Isabelle Oth, Veronika Schöpf, Karl-Heinz Nenning, Ulrika Asenbaum, Adelheid Wöhrer, Ramona Woitek, Georg Widhalm, Barbara Kiesel, Anna S. Berghoff, Johannes A. Hainfellner, Matthias Preusser, Daniela Prayer

21.06.2019 | Original Article

Performance of a Deep-Learning Neural Network to Detect Intracranial Aneurysms from 3D TOF-MRA Compared to Human Readers

The workload of radiology departments is steadily increasing [ 1 ]. According to the Organization for Economic Cooperation and Development (OECD), the total number of magnetic resonance imaging (MRI) scans performed in the USA was doubled between …

Anton Faron, Thorsten Sichtermann, Nikolas Teichert, Julian A. Luetkens, Annika Keulers, Omid Nikoubashman, Jessica Freiherr, Anastasios Mpotsaris, Martin Wiesmann

13.06.2019 | Original Article

Effect of MRI-based semiautomatic size-assessment in cerebral metastases on the RANO-BM classification

Cerebral metastases represent the largest entity of all malignant brain tumors and show a prevalence of approximately 25–35% in cancer patients. Morbidity and mortality in these patients are critically dependent on the response of cerebral …

Hans-Christian Bauknecht, Randolf Klingebiel, Patrick Hein, Claudia Wolf, Lars Bornemann, Eberhard Siebert, Georg Bohner