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Journal of Cancer Research and Clinical Oncology

Ausgabe 12/2025

Inhalt (36 Artikel)

ARNT2-driven transcriptional activation of STRA6 reprograms fatty acid metabolism to promote retroperitoneal liposarcoma progression

  • Open Access
  • Research

Junxiang Zhang, Hainan Guo, Bo Ban, Lin Yang, Jie Lian, Gan Li, Lindi Cai, Kai Deng, He Jiang, Xuqi Li, Shufeng Wang

Running session-conditioned human serum lowers prostate cancer cell spheroid formation

  • Open Access
  • Research

Giulia Baldelli, Alice Avancini, Diana Giannarelli, Lorenzo Budel, Veronica Gentilini, Anita Borsati, Linda Toniolo, Asja Conti, Michele Milella, Federico Schena, Giorgio Brandi, Sara Pilotto, Mauro De Santi, Cantor Tarperi

Molecular detection of HPV, EBV, and polyomaviruses in thyroid tumors and their clinicopathological relevance

  • Open Access
  • Research

Nagwan Ramadan, Omar Alfarouk Rabiee, Mohamed M. Hafez, Nasra F. Abdel Fattah, Eman Naguib Khorshed, Khaled Khalafalla, Auhood Nassar

Retraction Note: Belinostat and panobinostat (HDACI): in vitro and in vivo studies in thyroid cancer

  • Open Access
  • Retraction Note

Daniel Chan, Yun Zheng, Jeffrey W. Tyner, Wee Joo Chng, Wen Wen Chien, Sigal Gery, Geraldine Leong, Glenn D. Braunstein, H. Phillip Koeffler

Cancer incidence trends in Baden-Württemberg (Southwest Germany) during and after the COVID-19 pandemic (2020–2023)

  • Open Access
  • Research

Lina Jansen, Silke Hermann, Susanne Bergbold, Volker Arndt

E3 ubiquitin ligase BTRC inhibits the proliferation and tumor growth of glioma cells through the NFAT5/AQP4 axis

  • Open Access
  • Research

Yexin Li, Siqiang Tang, Kaiyuan Jiang, Peng Deng, Xiqi Hu

Response to PD-1 inhibition in MMRd/MSS pancreatic ductal adenocarcinoma: the relevance of parallel testing

  • Open Access
  • Case Report

Heike L. Pahl, Silke Lassmann, Anne M. Schultheis, Stephan Rau, Melanie Börries, Justus Duyster, Matthias Zaiss, Michael Quante, Heiko Becker

CGREF1 promotes cancer cell migration and predicts poor prognosis in colorectal cancer

  • Open Access
  • Research

Meijun Liu, Haixia Yang, Dan Zhang, Juanzhi Chen

Quality of life following total neoadjuvant therapy for rectal cancer

  • Open Access
  • Research

Georg W. Wurschi, Markus Diefenhardt, Justus Kaufmann, Hai Minh Ha, Melanie Schneider, Daphne Schepers von Ohlen, Maren Schöneich, Adrianna Cieslak, Alina Depardon, Jan-Niklas Becker, Alexander Rühle, Felix Ehret, Maximilian Römer, Florian Rißner, Andreas Hinz, Klaus Pietschmann

Intrahepatic cholangiocarcinoma as a unique subtype: key updates from current guidelines

  • Open Access
  • Research

Aaron Schindler, Timm Denecke, Daniel Seehofer, Florian van Bömmel, Thomas Berg

Cost-effectiveness analysis of pembrolizumab versus chemotherapy in advanced non-small cell lung cancer in China based on real-world studies

  • Open Access
  • Research

Ning Wan, Chen Yang, Bing Wang, Ya Guo, ZiJian He, YaJuan Lv, LiQing Lu, Ning Yang, WeiBin Xiao, YongBang Chen, Jin Yuan, DanDan Yang, Tao Liu, WenFeng Fang, ZhuoJia Chen, WeiTing Liang

Prognostic impact of central nervous system prophylaxis and a simplified BL model in primary testicular lymphoma: a real-world multicenter study

  • Open Access
  • Research

Shuozi Liu, Ping Yang, Yu Zhao, Shaowei Zhou, Hanxi Luo, Xinan Cen, Fei Dong, Wei Wan, Hongmei Jing

Immunotherapy with and without radiotherapy following the diagnosis of bone metastasis for stage IV non-small cell carcinoma

  • Open Access
  • Research

Jeffrey Beyon, Jennifer E. Collins, Christine A. Welch, Amir Kamran

Shared decision-making in cancer care in Bangladesh: evidence from a resource-constrained setting

  • Open Access
  • Research

Md. Shahjalal, Rushabh H. Doshi, Shriya K. Garg, Kathleen Buford Cartmell, Edward Christopher Dee

Computational identification of cross-reactive TCR epitopes with ARDitox

  • Open Access
  • Research

Victor Murcia Pienkowski, Tamara Boschert, Piotr Skoczylas, Anna Sanecka-Duin, Maciej Jasiński, Bartłomiej Król-Józaga, Giovanni Mazzocco, Sławomir Stachura, Lukas Bunse, Jan Kaczmarczyk, Edward W. Green, Agnieszka Blum

Distinct immunologic kinetics and cytomegalovirus reactivation incidence with rituximab- versus obinutuzumab–bendamustine in follicular lymphoma: a single-center case series study

  • Open Access
  • Research

Matteo D’Addona, Luca Pezzullo, Lorenzo Settembre, Emilia Vaccaro, Roberto Guariglia, Bianca Serio, Laura Mettivier, Andrea Gigantiello, Giovanni Signorile, Angela Bertolini, Francesca Picone, Bianca Cuffa, Valentina Giudice, Carmine Selleri

Immune checkpoint inhibition alters patterns of failure in inoperable stage III non-small cell lung cancer patients treated with chemoradiotherapy

  • Open Access
  • Research

Julian Taugner, Silja Stamer, Kerstin Hofstetter, Chukwuka Eze, Lukas Käsmann, Kerstin Clasen, Philipp Hartig, Werner Spengler, Thorben Groß, Farkhad Manapov, Claus Belka, Maximilian Niyazi

Prognostic impact of extranodal extension in oral cavity cancers: a retrospective analysis and implications for treatment intensification

  • Open Access
  • Research

Pragyat Thakur, Vedamanasa I, Ankur Dwivedi, Tapas K. Dora, Anshul Singla, Sankalp Sancheti, Alok Goel, Ashish Gulia, Arshdeep Kaur

Mapping the frontiers: a bibliometric perspective on t cell-based immunotherapy in pancreatic cancer since the twenty-first century

  • Open Access
  • Research

Ziniu Tang, Chen Wang, Zhenyu Ma, Peng Shang, Qipeng Yuan, Jinbo Yue

Fertility-sparing treatment for overweight patients with early-stage endometrial cancer or atypical endometrial hyperplasia under weight loss intervention

  • Open Access
  • Research

Mengdi Fu, Dongyan Cao, Qian Liu, Yuanli Feng, Mei Yu, Jiaxin Yang, Huimei Zhou, Ninghai Cheng, Xiangming Wu

DCN, NPM3 and SULF1 are hub genes related to vasculogenic mimicry in lung adenocarcinoma

  • Open Access
  • Research

Cheng Sun, Meifeng Ye, Weitao Cao, Jie Zeng, Zhike Liang, Yujun Li, Shuquan Wei, Zhuxiang Zhao, Ziwen Zhao

A clinical report and analysis of metachronous multiple primary cancers occurred in four sites

  • Open Access
  • Case Report

Rongze Sun, Hongxia Xie, Sijia He, Qi Li

Retraction Note: Signaling network involved in the GPC3-induced inhibition of breast cancer progression: role of canonical Wnt pathway

  • Open Access
  • Retraction Note

Dolores Fernández, Macarena Guereño, María Amparo Lago Huvelle, Magalí Cercato, María Giselle Peters

Patient-reported outcomes following various incision techniques in breast reconstruction: an observational cohort study in China

  • Open Access
  • Research

Lingzi Wang, Yuhang Song, Wenqin Huang, Senyang Guo, Xinhong Wu, Hongmei Zheng

Primary hemangioblastoma of rectum: a rare case report and review of literature

  • Open Access
  • Case Report

Aiping Zheng, Shaojuan Zhang, Qiang Ma, Wenxu Yang, Hualiang Xiao, Xinyu Liang

Integration of RASSF1A and TSPYL5 methylation and AFP protein as plasma biomarker for hepatocellular carcinoma diagnosis

  • Open Access

Haiyan Chen, Yingmin Luo, Linhong Li, Fei Xu, Xiaohuan Lai, Jinlong Li, Xiaomo Li, Wenjie Song, Yang Liu, Dengke Bao, Jiayun Liu, Guanlin Zhou, Shaogui Wan

Exploring the evolving role of apolipoproteins in oncology: global trends and emerging frontiers

  • Open Access
  • Research

Dianzhe Tian, Zixuan Hu, Zuyi Yang, Lvyuxing Zhao, Haitao Zhao, Xinting Sang, Shunda Du, Yunping Luo, Lei Zhang, Yiyao Xu, Xin Lu

Recent updates and future perspectives about ALDH1B1 as a potential anticancer target: a review

  • Open Access
  • Review

Tingting Zhao, Zhihong Sun, Zhenguo Li, Liujing Qu, Yulan Li, Jie Liu

Clinical application value of modified overlap anastomosis for Siewert type II and III adenocarcinoma of esophagogastric junction

  • Open Access
  • Research

Yong Fan, Linlin Hou, Han Zhang, Ruiting Zhang, Guoqing Shi, Qiuyan Li, Xingang Wang, Yuebin Wang, Qiuya Wei, Tianyu Gao

The role and mechanisms of the HIF-1 signaling pathway in LC-COPD

  • Open Access
  • Review

Yiting Zheng, Qian Jin

Surgical resection for pulmonary metastases from head and neck adenoid cystic carcinoma: a propensity-matched survival analysis

  • Open Access
  • Research

Zhen Yu, Xingguo Yang, Jun Wu, Xintao Yu, Jian Cui, Xiang Gao, Bobo Ma, Ji Ke, Baoxun Zhang, Xiaohong Chen, Lei Yu

Neu im Fachgebiet Onkologie

Ist eine HPV-Impfdosis ähnlich effektiv wie zwei?

Mangels verfügbarem HPV-Impfstoffs sind derzeit nur 27% der Mädchen weltweit geimpft. Um die Durchimpfung zu beschleunigen, hat die WHO ihre Empfehlungen auf eine Dosis angepasst. Nun zeigt eine große Studie, ob eine einzelne Impfdosis tatsächlich so wirksam wie zwei ist.

Läuft PAXG beim Pankreaskrebs mFOLFIRINOX den Rang ab?

In der perioperativen Chemotherapie des pankreatischen duktalen Adenokarzinoms markiert das mFOLFIRINOX-Schema bis dato eine Art Standard der Behandlung. Ein italienisches Onkologie-Forschungsteam wartet nun mit einem alternativen Vorschlag auf.

Glioblastom: Auf diese PPI sollten Sie verzichten

Eine Metaanalyse aus fünf Studien zeigt: Die Einnahme von Protonenpumpenhemmern (PPI) bei neu diagnostiziertem Glioblastom ist mit einem schlechteren Überleben assoziiert – allerdings nicht bei allen PPI.

Perioperative Ernährungstherapie oft nicht leitliniengerecht

Beim Ernährungsmanagement vor und nach einer Krebs-Op. im Gastrointestinaltrakt klafft offenbar eine große Lücke zwischen Leitlinienempfehlungen und klinischer Praxis. Darauf deuten die Ergebnisse einer Umfrage in 263 deutschen Zentren hin.

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Bildnachweise
Ein Kind wird von ärztlichen Personal geimpft/© kerkezz / stock.adobe.com (Symbolbild mit Fotomodellen), Infusion/© Trsakaoe / stock.adobe.com, Mann hält Tablette und Wasserglas/© Syda Productions / stock.adobe.com (Symbolbild mit Fotomodell), Person isst eine Krankenhaus-Mahlzeit/© gballgiggs / Stock.adobe.com (Symbolbild mit Fotomodell)