Ausgabe 1/2016
Inhalt (192 Artikel)
Molecular targeted therapy for the treatment of gastric cancer
Wenting Xu, Zhen Yang, Nonghua Lu
Maspin enhances cisplatin chemosensitivity in bladder cancer T24 and 5637 cells and correlates with prognosis of muscle-invasive bladder cancer patients receiving cisplatin based neoadjuvant chemotherapy
Jinbo Chen, Long Wang, Yunhua Tang, Guanghui Gong, Longfei Liu, Minfeng Chen, Zhi Chen, Yu Cui, Chao Li, Xu Cheng, Lin Qi, Xiongbing Zu
Synthetic Bax-Anti Bcl2 combination module actuated by super artificial hTERT promoter selectively inhibits malignant phenotypes of bladder cancer
Li Liu, Yuchen Liu, Tianbiao Zhang, Hanwei Wu, Muqi Lin, Chaoliang Wang, Yonghao Zhan, Qing Zhou, Baoping Qiao, Xiaojuan Sun, Qiaoxia Zhang, Xiaoqiang Guo, Guoping Zhao, Weixing Zhang, Weiren Huang
Anti-tumor effects of pigment epithelium-derived factor (PEDF): implication for cancer therapy. A mini-review
Louiza Belkacemi, Shaun Xiaoliu Zhang
Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer
Chenbo Ding, Junmin Luo, Longmei Li, Shanshan Li, Liwen Yang, Hongfei Pan, Qianyi Liu, Huan Qin, Chao Chen, Jihong Feng
JunB promotes cell invasion, migration and distant metastasis of head and neck squamous cell carcinoma
Hiroshi Hyakusoku, Daisuke Sano, Hideaki Takahashi, Takashi Hatano, Yasuhiro Isono, Shoko Shimada, Yusuke Ito, Jeffrey N. Myers, Nobuhiko Oridate
Radiation-induced miR-208a increases the proliferation and radioresistance by targeting p21 in human lung cancer cells
Yiting Tang, Yayun Cui, Zengpeng Li, Zhuqing Jiao, Yong Zhang, Yan He, Guangxia Chen, Qunyan Zhou, Wenjie Wang, Xifa Zhou, Judong Luo, Shuyu Zhang
The human RNA surveillance factor UPF1 regulates tumorigenesis by targeting Smad7 in hepatocellular carcinoma
Lei Chang, Cuicui Li, Tao Guo, Haitao Wang, Weijie Ma, Yufeng Yuan, Quanyan Liu, Qifa Ye, Zhisu Liu
The leukemogenic fusion gene MLL-AF9 alters microRNA expression pattern and inhibits monoblastic differentiation via miR-511 repression
Katrin K. Fleischmann, Philipp Pagel, Julia von Frowein, Thomas Magg, Adelbert A. Roscher, Irene Schmid
MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist
Xiaochun Sun, Manhua Cui, Aichen Zhang, Lingling Tong, Kun Wang, Kai Li, Xue Wang, Ziqian Sun, Hongye Zhang
MicroRNA-106b is involved in transforming growth factor β1–induced cell migration by targeting disabled homolog 2 in cervical carcinoma
Yuan Cheng, Yanli Guo, Youyi Zhang, Ke You, Zijian Li, Li Geng
Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma
Yong Hu, Meng-Ying He, Li-Fang Zhu, Cong-Chong Yang, Mei-Ling Zhou, Qiong Wang, Wei Zhang, Yang-Yu Zheng, Dong-Miao Wang, Zeng-Qi Xu, Yu-Nong Wu, Lai-Kui Liu
Interleukin-37 suppresses tumor growth through inhibition of angiogenesis in non-small cell lung cancer
Guanqun Ge, Aiqin Wang, Jingyue Yang, Yan Chen, Jin Yang, Yize Li, Yan Xue
Direct targeting sperm-associated antigen 9 by miR-141 influences hepatocellular carcinoma cell growth and metastasis via JNK pathway
Guohua Lou, Xuejun Dong, Caixia Xia, Bingjue Ye, Qiuyue Yan, Shanshan Wu, Ye Yu, Feifei Liu, Min Zheng, Zhi Chen, Yanning Liu
Elevated HOXA1 expression correlates with accelerated tumor cell proliferation and poor prognosis in gastric cancer partly via cyclin D1
Chenwei Yuan, Xingwu Zhu, Yang Han, Chenlong Song, Chenchen Liu, Su Lu, Meng Zhang, Fudong Yu, Zhihai Peng, Chongzhi Zhou
Neuropilin-1 is associated with clinicopathology of gastric cancer and contributes to cell proliferation and migration as multifunctional co-receptors
Linhao Li, Xian Jiang, Qian Zhang, Xuesong Dong, Yuqiang Gao, Yuanlong He, Haiquan Qiao, Fangyu Xie, Xiangjun Xie, Xueying Sun
Integrated analysis of microRNA regulatory network in nasopharyngeal carcinoma with deep sequencing
Fan Wang, Juan Lu, Xiaohong Peng, Jie Wang, Xiong Liu, Xiaomei Chen, Yiqi Jiang, Xiangping Li, Bao Zhang
Eliciting cytotoxic T lymphocytes against human laryngeal cancer-derived antigens: evaluation of dendritic cells pulsed with a heat-treated tumor lysate and other antigen-loading strategies for dendritic-cell-based vaccination
Fan-Qin Wei, Wei Sun, Thian-Sze Wong, Wei Gao, Yi-Hui Wen, Jia-Wei Wei, Yi Wei, Wei-Ping Wen
MiR-130a-3p regulates cell migration and invasion via inhibition of Smad4 in gemcitabine resistant hepatoma cells
Yang Liu, Yumei Li, Rui Wang, Shukui Qin, Jing Liu, Fang Su, Yan Yang, Fuyou Zhao, Zishu Wang, Qiong Wu
Erratum to: Radiation-induced miR-208a increases the proliferation and radioresistance by targeting p21 in human lung cancer cells
Yiting Tang, Yayun Cui, Zengpeng Li, Zhuqing Jiao, Yong Zhang, Yan He, Guangxia Chen, Qunyan Zhou, Wenjie Wang, Xifa Zhou, Judong Luo, Shuyu Zhang
MicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cancer
Tingting Li, Qiuhua Lai, Shuyang Wang, Juanjuan Cai, Zhiyuan Xiao, Danling Deng, Liuqing He, Hongli Jiao, Yaping Ye, Li Liang, Yanqing Ding, Wenting Liao
Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulating miR-107/CDK6 pathway
Peng Wang, Tianyi Wu, Han Zhou, Qianqian Jin, Guoqing He, Haoyang Yu, Lijia Xuan, Xin Wang, Linli Tian, Yanan Sun, Ming Liu, Lingmei Qu
Targeting autophagy to sensitive glioma to temozolomide treatment
Yuanliang Yan, Zhijie Xu, Shuang Dai, Long Qian, Lunquan Sun, Zhicheng Gong
Epitelial-to-mesenchimal transition and invasion are upmodulated by tumor-expressed granzyme B and inhibited by docosahexaenoic acid in human colorectal cancer cells
Donatella D’Eliseo, Giuliana Di Rocco, Rossella Loria, Silvia Soddu, Angela Santoni, Francesca Velotti
MiR-302a/b/c/d cooperatively sensitizes breast cancer cells to adriamycin via suppressing P-glycoprotein(P-gp) by targeting MAP/ERK kinase kinase 1 (MEKK1)
Lin Zhao, Yan Wang, Longyang Jiang, Miao He, Xuefeng Bai, Lifeng Yu, Minjie Wei
HIF-2α promotes epithelial-mesenchymal transition through regulating Twist2 binding to the promoter of E-cadherin in pancreatic cancer
Jian Yang, Xu Zhang, Yi Zhang, Dongming Zhu, Lifeng Zhang, Ye Li, Yanbo Zhu, Dechun Li, Jian Zhou
RETRACTED ARTICLE: Transcriptional repression of SOCS3 mediated by IL-6/STAT3 signaling via DNMT1 promotes pancreatic cancer growth and metastasis
Li Huang, Bin Hu, Jianbo Ni, Jianghong Wu, Weiliang Jiang, Congying Chen, Lijuan Yang, Yue Zeng, Rong Wan, Guoyong Hu, Xingpeng Wang
Journal of Experimental & Clinical Cancer Research reviewer acknowledgement 2015
Mauro Castelli
LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1α activation
Jingjing Zhang, Lingyin Zhu, Jingyuan Fang, Zhizheng Ge, Xiaobo Li
Erratum to: Linc00152 promotes proliferation in gastric cancer through the EGFR-dependent pathway
Jianping Zhou, Xiaofei Zhi, Linjun Wang, Weizhi Wang, Zheng Li, Jie Tang, Jiwei Wang, Qun Zhang, Zekuan Xu
MiR-23b targets cyclin G1 and suppresses ovarian cancer tumorigenesis and progression
Jing Yan, Jing-yi Jiang, Xiao-Na Meng, Yin-Ling Xiu, Zhi-Hong Zong
Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro
Caixing Sun, Yang Yu, Lizhen Wang, Bin Wu, Liang Xia, Fang Feng, Zhiqiang Ling, Shihua Wang
Atorvastatin (Lipitor) attenuates the effects of aspirin on pancreatic cancerogenesis and the chemotherapeutic efficacy of gemcitabine on pancreatic cancer by promoting M2 polarized tumor associated macrophages
Qiaofei Liu, Yuan Li, Zheyu Niu, Yi Zong, Mengyi Wang, Lutian Yao, Zhaohui Lu, Quan Liao, Yupei Zhao
UHRF1 overexpression is involved in cell proliferation and biochemical recurrence in prostate cancer after radical prostatectomy
Xuechao Wan, Shu Yang, Wenhua Huang, Denglong Wu, Hongbing Chen, Ming Wu, Junliang Li, Tao Li, Yao Li
Overexpression of proteasomal activator PA28α serves as a prognostic factor in oral squamous cell carcinoma
Xiaodong Feng, Yuchen Jiang, Liang Xie, Lu Jiang, Jing Li, Chongkui Sun, Hao Xu, Ruinan Wang, Min Zhou, Yu Zhou, Hongxia Dan, Zhiyong Wang, Ning Ji, Peng Deng, Ga Liao, Ning Geng, Yun Wang, Dunfang Zhang, Yunfeng Lin, Ling Ye, Xinhua Liang, Longjiang Li, Gang Luo, Mingye Feng, Juan Fang, Xin Zeng, Zhi Wang, Qianming Chen
Pharmacological blockade of aquaporin-1 water channel by AqB013 restricts migration and invasiveness of colon cancer cells and prevents endothelial tube formation in vitro
Hilary S. Dorward, Alice Du, Maressa A. Bruhn, Joseph Wrin, Jinxin V. Pei, Andreas Evdokiou, Timothy J. Price, Andrea J. Yool, Jennifer E. Hardingham
Depletion of histone demethylase KDM5B inhibits cell proliferation of hepatocellular carcinoma by regulation of cell cycle checkpoint proteins p15 and p27
Dong Wang, Sheng Han, Rui Peng, Chenyu Jiao, Xing Wang, Xinxiang Yang, Renjie Yang, Xiangcheng Li
CD146 promotes metastasis and predicts poor prognosis of hepatocellular carcinoma
Guoqing Jiang, Long Zhang, Qin Zhu, Dousheng Bai, Chuanyong Zhang, Xuehao Wang
Murine mesothelin: characterization, expression, and inhibition of tumor growth in a murine model of pancreatic cancer
Emmanuel Zervos, Steven Agle, Andrew G. Freistaedter, Gwendolyn J. B. Jones, Rachel L. Roper
Anti-tumor effects of Atractylenolide I on bladder cancer cells
Rui Yu, Bi-xia Yu, Jun-feng Chen, Xiu-yi Lv, Ze-jun Yan, Yue Cheng, Qi Ma
N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells
Min Wang, Ankun Zhou, Tao An, Lingmei Kong, Chunlei Yu, Jianmei Liu, Chengfeng Xia, Hongyu Zhou, Yan Li
The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast
Haidan Jin, Meiying Ji, Liyan Chen, Qixiang Liu, Shuanlong Che, Ming Xu, Zhenhua Lin
MicroRNAs in colorectal carcinoma - from pathogenesis to therapy
Yudan Chi, Dongming Zhou
Inhibition of SOX2 induces cell apoptosis and G1/S arrest in Ewing’s sarcoma through the PI3K/Akt pathway
Chongmin Ren, Tingting Ren, Kang Yang, Shidong Wang, Xing Bao, Fan Zhang, Wei Guo
Dysregulation of microRNA biogenesis in cancer: the impact of mutant p53 on Drosha complex activity
Aymone Gurtner, Emmanuela Falcone, Francesca Garibaldi, Giulia Piaggio
Pancreatic cancer cell-derived IGFBP-3 contributes to muscle wasting
Xiu-yan Huang, Zi-li Huang, Ju-hong Yang, Yong-hua Xu, Jiu-Song Sun, Qi Zheng, Chunyao Wei, Wei Song, Zhou Yuan
RETRACTED ARTICLE: MicroRNA-203 suppresses gastric cancer growth by targeting PIBF1/Akt signaling
Shao-Jun Chu, Ge Wang, Peng-Fei Zhang, Rui Zhang, Yan-Xia Huang, Yun-Min Lu, Wei Da, Qun Sun, Jing Zhang, Jin-Shui Zhu
Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4
Koichi Fujisawa, Shuji Terai, Taro Takami, Naoki Yamamoto, Takahiro Yamasaki, Toshihiko Matsumoto, Kazuhito Yamaguchi, Yuji Owada, Hiroshi Nishina, Takafumi Noma, Isao Sakaida
Flow cytometry remission by Ig light chains ratio is a powerful marker of outcome in multiple myeloma after tandem autologous transplant: a real-life study
Iole Cordone, Francesco Marchesi, Serena Masi, Valentina Summa, Francesco Pisani, Roberta Merola, Giovanni Cigliana, Giulia Orlandi, Svitlana Gumenyuk, Francesca Palombi, Atelda Romano, Antonio Spadea, Daniela Renzi, Elena Papa, Marco Canfora, Laura Conti, Maria Concetta Petti, Andrea Mengarelli
Subpopulation Treatment Effect Pattern Plot (STEPP) analysis of Ki67 assay according to histology: prognostic relevance for resected early stage ‘pure’ and ‘mixed’ lobular breast cancer
Luisa Carbognin, Isabella Sperduti, Matteo Brunelli, Lisa Marcolini, Rolando Nortilli, Sara Pilotto, Ilaria Zampiva, Sara Merler, Elena Fiorio, Elisa Filippi, Erminia Manfrin, Francesca Pellini, Franco Bonetti, Giovanni Paolo Pollini, Giampaolo Tortora, Emilio Bria
CCR7 mediates the TNF-α-induced lymphatic metastasis of gallbladder cancer through the “ERK1/2 - AP-1” and “JNK - AP-1” pathways
HaiJie Hong, CaiLong He, SiYuan Zhu, YanHui Zhang, XiaoQian Wang, FeiFei She, YanLing Chen
Low dose of lenalidmide and PI3K/mTOR inhibitor trigger synergistic cytoxicity in activated B cell-like subtype of diffuse large B cell lymphoma
Zhen Jin, Kai Qing, Yuan Ouyang, Zhao Liu, Wenfang Wang, Xiaoyang Li, Zizhen Xu, Junmin Li
Targeted p53 activation by saRNA suppresses human bladder cancer cells growth and metastasis
Chenghe Wang, Qiangqiang Ge, Qingsong Zhang, Zhong Chen, Jia Hu, Fan Li, Zhangqun Ye
Phosphatidylserine exposing-platelets and microparticles promote procoagulant activity in colon cancer patients
Liangliang Zhao, Yayan Bi, Junjie Kou, Jialan Shi, Daxun Piao
Targeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma model
Laura Mercurio, Maria Antonietta Ajmone-Cat, Serena Cecchetti, Alessandro Ricci, Giuseppina Bozzuto, Agnese Molinari, Isabella Manni, Bianca Pollo, Stefania Scala, Giulia Carpinelli, Luisa Minghetti
Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations
Niels Frank Jensen, Keli Agama, Amit Roy, David Hersi Smith, Thomas D. Pfister, Maria Unni Rømer, Hong-Liang Zhang, James H. Doroshow, Birgitta R. Knudsen, Jan Stenvang, Nils Brünner, Yves Pommier
Sustained delivery of siRNA/PEI complex from in situ forming hydrogels potently inhibits the proliferation of gastric cancer
Hao Peng, Huawei Yang, Liwei Song, Zheng Zhou, Jinwen Sun, Yunfeng Du, Keyu Lu, Tao Li, Aiguo Yin, Jianhua Xu, Shidong Wei
Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell
Mohadeseh Hasanpourghadi, Chandrabose Karthikeyan, Ashok Kumar Pandurangan, Chung Yeng Looi, Piyush Trivedi, Kinue Kobayashi, Kozo Tanaka, Won Fen Wong, Mohd Rais Mustafa
Inter-regulation of IGFBP1 and FOXO3a unveils novel mechanism in ursolic acid-inhibited growth of hepatocellular carcinoma cells
LiJun Yang, Qing Tang, Jingjing Wu, Yuqing Chen, Fang Zheng, Zhenhui Dai, Swei Sunny Hann
miR-539 inhibits prostate cancer progression by directly targeting SPAG5
Hongtuan Zhang, Shadan Li, Xiong Yang, Baomin Qiao, Zhihong Zhang, Yong Xu
Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo
Junyang Li, Chao Tang, Liwen Li, Rujun Li, Youwu Fan
Topographic expression of the Hippo transducers TAZ and YAP in triple-negative breast cancer treated with neoadjuvant chemotherapy
Patrizia Vici, Cristiana Ercolani, Anna Di Benedetto, Laura Pizzuti, Luigi Di Lauro, Francesca Sperati, Irene Terrenato, Teresa Gamucci, Clara Natoli, Franco Di Filippo, Claudio Botti, Maddalena Barba, Marcella Mottolese, Ruggero De Maria, Marcello Maugeri-Saccà
Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway
Zhai Ertao, Chen Jianhui, Chen Chuangqi, Qin Changjiang, Chen Sile, He Yulong, Wu Hui, Cai Shirong
High expression of ID family and IGJ genes signature as predictor of low induction treatment response and worst survival in adult Hispanic patients with B-acute lymphoblastic leukemia
Nataly Cruz-Rodriguez, Alba L. Combita, Leonardo J. Enciso, Sandra M. Quijano, Paula L. Pinzon, Olga C. Lozano, Juan S. Castillo, Li Li, Jose Bareño, Claudia Cardozo, Julio Solano, Maria V. Herrera, Jennifer Cudris, Jovanny Zabaleta
EphA1 activation promotes the homing of endothelial progenitor cells to hepatocellular carcinoma for tumor neovascularization through the SDF-1/CXCR4 signaling pathway
Yi Wang, Haitao Yu, Yunfeng Shan, Chonglin Tao, Fang Wu, Zhengping Yu, Pengyi Guo, Jianfei Huang, Junjian Li, Qiandong Zhu, Fuxiang Yu, Qitong Song, Hongqi Shi, Mengtao Zhou, Gang Chen
Clinical significance of pancreatic circulating tumor cells using combined negative enrichment and immunostaining-fluorescence in situ hybridization
Yang Gao, Yayun Zhu, Zhenzhen Zhang, Cheng Zhang, Xinyu Huang, Zhou Yuan
Protein phosphatase 2A-B55δ enhances chemotherapy sensitivity of human hepatocellular carcinoma under the regulation of microRNA-133b
Qunying Zhuang, Tengjian Zhou, Chengyong He, Shili Zhang, Yang Qiu, Bing Luo, Ran Zhao, Hengchuan Liu, Yuchun Lin, Zhongning Lin
Prohibitin overexpression predicts poor prognosis and promotes cell proliferation and invasion through ERK pathway activation in gallbladder cancer
Yang Cao, Haibin Liang, Fei Zhang, Zhou Luan, Shuai Zhao, Xu-an Wang, Shibo Liu, Runfa Bao, Yijun Shu, Qiang Ma, Jian Zhu, Yingbin Liu
MicroRNA-138 functions as a tumor suppressor in osteosarcoma by targeting differentiated embryonic chondrocyte gene 2
Baoen Jiang, Weidong Mu, Jiangquan Wang, Jianshu Lu, Shanyong Jiang, Liang Li, Haining Xu, Hongyan Tian
Biological evaluation of antibody-maytansinoid conjugates as a strategy of RON targeted drug delivery for treatment of non-small cell lung cancer
Liang Feng, Hang-Ping Yao, Sharad Sharma, Yong-Qing Zhou, Jianwei Zhou, Ruiwen Zhang, Ming-Hai Wang
Enhancement of anti-tumor effects of 5-fluorouracil on hepatocellular carcinoma by low-intensity ultrasound
Zheng Hu, Guixiang Lv, Yongning Li, Enze Li, Haixia Li, Qi Zhou, Bin Yang, Wenwu Cao
TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells
Zhongxue Ye, Jie Li, Xi Han, Huilian Hou, He Chen, Xia Zheng, Jiaojiao Lu, Lijie Wang, Wei Chen, Xu Li, Le Zhao
Green tea and quercetin sensitize PC-3 xenograft prostate tumors to docetaxel chemotherapy
Piwen Wang, Susanne M. Henning, Clara E. Magyar, Yahya Elshimali, David Heber, Jaydutt V. Vadgama
Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model
Adel Galal El-Shemi, Ahmad Mohammed Ashshi, Youjin Na, Yan Li, Mohammed Basalamah, Faisal Ahmad Al-Allaf, Eonju Oh, Bo-Kyeong Jung, Chae-Ok YUN
High expression of long non-coding RNA SBF2-AS1 promotes proliferation in non-small cell lung cancer
Junjie Lv, Mantang Qiu, Wenjia Xia, Chao Liu, Youtao Xu, Jie Wang, Xuechun Leng, Su Huang, Rong Zhu, Ming Zhao, Fengqing Ji, Lin Xu, Keping Xu, Rong Yin
MicroRNA-361-3p suppresses tumor cell proliferation and metastasis by directly targeting SH2B1 in NSCLC
Wei Chen, Jun Wang, Sulai Liu, Shaoqiang Wang, Yuanda Cheng, Wolong Zhou, Chaojun Duan, Chunfang Zhang
Erratum to: Pancreatic cancer cell-derived IGFBP-3 contributes to muscle wasting
Xiu-yan Huang, Zi-li Huang, Ju-hong Yang, Yong-hua Xu, Jiu-Song Sun, Qi Zheng, Chunyao Wei, Wei Song, Zhou Yuan
PI3K p110β isoform synergizes with JNK in the regulation of glioblastoma cell proliferation and migration through Akt and FAK inhibition
Hua-Fu Zhao, Jing Wang, Hao-Ran Jiang, Zhong-Ping Chen, Shing-Shun Tony To
FLIPL is critical for aerobic glycolysis in hepatocellular carcinoma
Shixiong Lei, Jiandong Yang, Chong Chen, Jiachen Sun, Liu Yang, Haili Tang, Tao Yang, An Chen, Huadong Zhao, Yan Li, Xilin Du
Transfer of malignant trait to BRCA1 deficient human fibroblasts following exposure to serum of cancer patients
Dana Hamam, Mohamed Abdouh, Zu-Hua Gao, Vincenzo Arena, Manuel Arena, Goffredo Orazio Arena
Erratum to: Inter-regulation of IGFBP1 and FOXO3a unveils novel mechanism in ursolic acid-inhibited growth of hepatocellular carcinoma cells
LiJun Yang, Qing Tang, Jingjing Wu, Yuqing Chen, Fang Zheng, Zhenhui Dai, Swei Sunny Hann
Overexpression of CTNND1 in hepatocellular carcinoma promotes carcinous characters through activation of Wnt/β-catenin signaling
Bo Tang, Fang Tang, Zhenran Wang, Guangying Qi, Xingsi Liang, Bo Li, Shengguang Yuan, Jie Liu, Shuiping Yu, Songqing He
Up-regulation of long non-coding RNA PANDAR is associated with poor prognosis and promotes tumorigenesis in bladder cancer
Yonghao Zhan, Junhao Lin, Yuchen Liu, Mingwei Chen, Xiaoying Chen, Chengle Zhuang, Li Liu, Wen Xu, Zhicong Chen, Anbang He, Qiaoxia Zhang, Xiaojuan Sun, Guoping Zhao, Weiren Huang
Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication
Samantha Kaufhold, Hermes Garbán, Benjamin Bonavida
Elevated MTSS1 expression associated with metastasis and poor prognosis of residual hepatitis B-related hepatocellular carcinoma
Xiu-Yan Huang, Zi-Li Huang, Bin Xu, Zi Chen, Thomas Joseph Re, Qi Zheng, Zhao-You Tang, Xin-Yu Huang
The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas
Hao-Yuan Wang, Kai Tang, Ting-Yu Liang, Wei-Zhong Zhang, Ji-Ye Li, Wen Wang, Hui-Min Hu, Ming-Yang Li, Hui-Qing Wang, Xiao-Zheng He, Zhi-Yuan Zhu, Yan-Wei Liu, Shi-Zhong Zhang
Hepatitis B virus whole-X and X protein play distinct roles in HBV-related hepatocellular carcinoma progression
Yu Zhang, Hongli Liu, Ruitian Yi, Taotao Yan, Yingli He, Yingren Zhao, Jinfeng Liu
RNF8 promotes epithelial-mesenchymal transition of breast cancer cells
Jingyu Kuang, Li Li, Limei Guo, Yanrong Su, Yuxuan Wang, Yongjie Xu, Xiaozhen Wang, Shucong Meng, Liandi Lei, Luzheng Xu, Genze Shao
MicroRNA-655-3p functions as a tumor suppressor by regulating ADAM10 and β-catenin pathway in Hepatocellular Carcinoma
Gang Wu, Kunming Zheng, Shuguan Xia, Yawei Wang, Xiangyu Meng, Xiaoming Qin, Ying Cheng
Long non-coding RNA ATB promotes glioma malignancy by negatively regulating miR-200a
Chun-Chun Ma, Zhang Xiong, Guan-Nan Zhu, Chao Wang, Gang Zong, Hong-Liang Wang, Er-Bao Bian, Bing Zhao
The role of the AMOP domain in MUC4/Y-promoted tumour angiogenesis and metastasis in pancreatic cancer
Jie Tang, Yi Zhu, Kunling Xie, Xiaoyu Zhang, Xiaofei Zhi, Weizhi Wang, Zheng Li, Qun Zhang, Linjun Wang, Jiwei Wang, Zekuan Xu
Decreased brain-expressed X-linked 4 (BEX4) expression promotes growth of oral squamous cell carcinoma
Wei Gao, John Zeng-Hong Li, Si-Qi Chen, Chiao-Yun Chu, Jimmy Yu-Wai Chan, Thian-Sze Wong
MicroRNA-155-3p promotes hepatocellular carcinoma formation by suppressing FBXW7 expression
Bo Tang, Biao Lei, Guangying Qi, Xingsi Liang, Fang Tang, Shengguang Yuan, Zhenran Wang, Shuiping Yu, Songqing He
Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs
Ina Patties, Rolf-Dieter Kortmann, Franziska Menzel, Annegret Glasow
Erratum to: Biological evaluation of antibody-maytansinoid conjugates as a strategy of RON targeted drug delivery for treatment of non-small cell lung cancer
Liang Feng, Hang-Ping Yao, Sharad Sharma, Yong-Qing Zhou, Jianwei Zhou, Ruiwen Zhang, Ming-Hai Wang
Erratum to: Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model
Adel Galal El-Shemi, Ahmad Mohammed Ashshi, Youjin Na, Yan Li, Mohammed Basalamah, Faisal Ahmad Al-Allaf, Eonju Oh, Bo-Kyeong Jung, Chae-Ok YUN
The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR
Shuai Zhao, Yang Cao, Shi-bo Liu, Xu-an Wang, Run-fa Bao, Yi-jun Shu, Yun-ping Hu, Yi-jian Zhang, Lin Jiang, Fei Zhang, Hai-bin Liang, Huai-feng Li, Qiang Ma, Yi Xu, Zheng Wang, Yi-chi Zhang, Lei Chen, Jian Zhou, Ying-bin Liu
Inhibition of SALL4 reduces tumorigenicity involving epithelial-mesenchymal transition via Wnt/β-catenin pathway in esophageal squamous cell carcinoma
Jing He, Mingxia Zhou, Xinfeng Chen, Dongli Yue, Li Yang, Guohui Qin, Zhen Zhang, Qun Gao, Dan Wang, Chaoqi Zhang, Lan Huang, Liping Wang, Bin Zhang, Jane Yu, Yi Zhang
Synthetic tetracycline-controllable shRNA targeting long non-coding RNA HOXD-AS1 inhibits the progression of bladder cancer
Jianfa Li, Chengle Zhuang, Yuchen Liu, Mingwei Chen, Yincong Chen, Zhicong Chen, Anbang He, Junhao Lin, Yonghao Zhan, Li Liu, Wen Xu, Guoping Zhao, Yinglu Guo, Hanwei Wu, Zhiming Cai, Weiren Huang
RETRACTED ARTICLE: TRIM11 overexpression promotes proliferation, migration and invasion of lung cancer cells
Xiaolin Wang, Weiping Shi, Hongcan Shi, Shichun Lu, Kang Wang, Chao Sun, Jiansheng He, Weiguo Jin, Xiaoxia Lv, Hui Zou, Yusheng Shu
miRNA-106a directly targeting RARB associates with the expression of Na+/I− symporter in thyroid cancer by regulating MAPK signaling pathway
Chen-Tian Shen, Zhong-Ling Qiu, Hong-Jun Song, Wei-Jun Wei, Quan-Yong Luo
Erratum to: Elevated MTSS1 expression associated with metastasis and poor prognosis of residual hepatitis B-related hepatocellular carcinoma
Xiu-Yan Huang, Zi-Li Huang, Bin Xu, Zi Chen, Thomas Joseph Re, Qi Zheng, Zhao-You Tang, Xin-Yu Huang
Targeting microRNAs as key modulators of tumor immune response
Laura Paladini, Linda Fabris, Giulia Bottai, Carlotta Raschioni, George A. Calin, Libero Santarpia
First-line therapy in HER2 positive metastatic breast cancer: is the mosaic fully completed or are we missing additional pieces?
Alessandra Fabi, Paola Malaguti, Sabrina Vari, Francesco Cognetti
RETRACTED ARTICLE: MicroRNA-130b promotes lung cancer progression via PPARγ/VEGF-A/BCL-2-mediated suppression of apoptosis
Jianwei Tian, Liping Hu, Xiao Li, Jian Geng, Meng Dai, Xiaoyan Bai
Interleukin-9 promotes cell survival and drug resistance in diffuse large B-cell lymphoma
Xiao Lv, Lili Feng, Xueling Ge, Kang Lu, Xin Wang
Enhanced therapeutic effect of an antiangiogenesis peptide on lung cancer in vivo combined with salmonella VNP20009 carrying a Sox2 shRNA construct
Changhong Zhao, Junjin He, Haoran Cheng, Zhaohao Zhu, Hanmei Xu
ATF2 predicts poor prognosis and promotes malignant phenotypes in renal cell carcinoma
Deng-shuang Wu, Cheng Chen, Zhen-jie Wu, Bing Liu, Li Gao, Qing Yang, Wei Chen, Jun-ming Chen, Yi Bao, Le Qu, Lin-hui Wang
YPEL3 suppresses epithelial–mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway
Jian Zhang, Xin Wen, Xian-Yue Ren, Ying-Qin Li, Xin-Ran Tang, Ya-Qin Wang, Qing-Mei He, Xiao-Jing Yang, Ying Sun, Na Liu, Jun Ma
1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis
Agnieszka Blazejczyk, Marta Switalska, Stefan Chlopicki, Andrzej Marcinek, Jerzy Gebicki, Marcin Nowak, Anna Nasulewicz-Goldeman, Joanna Wietrzyk
Nestin overexpression in hepatocellular carcinoma associates with epithelial-mesenchymal transition and chemoresistance
Yan Zhang, Shan Zeng, Junli Ma, Ganlu Deng, Yanlin Qu, Cao Guo, Hong Shen
Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I
Longmei Li, JingJing Wu, Fang Zheng, Qing Tang, WanYin Wu, Swei Sunny Hann
Evaluation of intraarterial and intravenous cisplatin chemotherapy in the treatment of metastatic osteosarcoma using an orthotopic xenograft mouse model
Bernhard Robl, Sander Martijn Botter, Giovanni Pellegrini, Olga Neklyudova, Bruno Fuchs
Activation of the JNK-c-Jun pathway in response to irradiation facilitates Fas ligand secretion in hepatoma cells and increases hepatocyte injury
Yinying Dong, Xiaoyun Shen, Mingyan He, Zhifeng Wu, Qiongdan Zheng, Yaohui Wang, Yuhan Chen, Sifan Wu, Jiefeng Cui, Zhaochong Zeng
SYNJ2BP inhibits tumor growth and metastasis by activating DLL4 pathway in hepatocellular carcinoma
Xiao Liu, Jiangjiao Zhou, Ning Zhou, Jianwei Zhu, Yong Feng, Xiongying Miao
Nerve growth factor: role in growth, differentiation and controlling cancer cell development
Luigi Aloe, Maria Luisa Rocco, Bijorn Omar Balzamino, Alessandra Micera
CD317 Promotes the survival of cancer cells through apoptosis-inducing factor
Xin Li, Guizhong Zhang, Qian Chen, Yingxue Lin, Junxin Li, Qingguo Ruan, Youhai Chen, Guang Yu, Xiaochun Wan
Downregulation of proinflammatory cytokines in HTLV-1-infected T cells by Resveratrol
Maria Pia Fuggetta, Valentina Bordignon, Andrea Cottarelli, Beatrice Macchi, Caterina Frezza, Paola Cordiali-Fei, Fabrizio Ensoli, Stefania Ciafrè, Francesca Marino-Merlo, Antonio Mastino, Giampietro Ravagnan
Hyperthermia induced HIF-1a expression of lung cancer through AKT and ERK signaling pathways
Jun Wan, Wei Wu
DNA methylation of claudin-6 promotes breast cancer cell migration and invasion by recruiting MeCP2 and deacetylating H3Ac and H4Ac
Yafang Liu, Xiangshu Jin, Yanru Li, Yang Ruan, Yan Lu, Minlan Yang, Dongjing Lin, Peiye Song, Yantong Guo, Shuai Zhao, Bing Dong, Yinping Xie, Qihua Dang, Chengshi Quan
β-arrestin1 at the cross-road of endothelin-1 signaling in cancer
Laura Rosanò, Anna Bagnato
The TGFβ-SMAD3 pathway inhibits IL-1α induced interactions between human pancreatic stellate cells and pancreatic carcinoma cells and restricts cancer cell migration
Vegard Tjomsland, Dagny Sandnes, Ewa Pomianowska, Smiljana Torbica Cizmovic, Monica Aasrum, Ingvild Johnsen Brusevold, Thoralf Christoffersen, Ivar P. Gladhaug
Sam68 reduces cisplatin-induced apoptosis in tongue carcinoma
Shuwei Chen, Huan Li, Shimin Zhuang, Ji Zhang, Fan Gao, Xidi Wang, WenKuan Chen, Ming Song
A restricted signature of serum miRNAs distinguishes glioblastoma from lower grade gliomas
Giulia Regazzo, Irene Terrenato, Manuela Spagnuolo, Mariantonia Carosi, Gaetana Cognetti, Lucia Cicchillitti, Francesca Sperati, Veronica Villani, Carmine Carapella, Giulia Piaggio, Andrea Pelosi, Maria Giulia Rizzo
Over-expression of long noncoding RNA BANCR inhibits malignant phenotypes of human bladder cancer
Anbang He, Yuchen Liu, Zhicong Chen, Jianfa Li, Mingwei Chen, Li Liu, Xinhui Liao, Zhaojie Lv, Yonghao Zhan, Chengle Zhuang, Junhao Lin, Weiren Huang, Hongbing Mei
Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin
Corina Buta, Eva Benabou, Marie Lequoy, Hélène Régnault, Dominique Wendum, Fatiha Merabtene, Hamza Chettouh, Lynda Aoudjehane, Filomena Conti, Yves Chrétien, Olivier Scatton, Olivier Rosmorduc, Françoise Praz, Laetitia Fartoux, Christèle Desbois-Mouthon
Microarray-based identification of genes associated with cancer progression and prognosis in hepatocellular carcinoma
Fuqiang Yin, Lipei Shu, Xia Liu, Ting Li, Tao Peng, Yueli Nan, Shu Li, Xiaoyun Zeng, Xiaoqiang Qiu
Brain stereotactic biopsy flow cytometry for central nervous system lymphoma characterization: advantages and pitfalls
Iole Cordone, Serena Masi, Mariantonia Carosi, Antonello Vidiri, Francesco Marchesi, Mirella Marino, Stefano Telera, Alessia Pasquale, Andrea Mengarelli, Laura Conti, Edoardo Pescarmona, Andrea Pace, Carmine M. Carapella
Induction of the mesenchymal to epithelial transition by demethylation-activated microRNA-125b is involved in the anti-migration/invasion effects of arsenic trioxide on human chondrosarcoma
Xing Bao, Tingting Ren, Yi Huang, Shidong Wang, Fan Zhang, Kuisheng Liu, Bingxin Zheng, Wei Guo
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways
Xiang Zhuang, Mengxin Lv, Zhenyu Zhong, Luyu Zhang, Rong Jiang, Junxia Chen
Deletion of interleukin-6 in monocytes/macrophages suppresses the initiation of hepatocellular carcinoma in mice
Lingxiang Kong, Yongjie Zhou, Hong Bu, Tao Lv, Yujun Shi, Jiayin Yang
MiR-137 and miR-34a directly target Snail and inhibit EMT, invasion and sphere-forming ability of ovarian cancer cells
Peixin Dong, Ying Xiong, Hidemichi Watari, Sharon J. B. Hanley, Yosuke Konno, Kei Ihira, Takahiro Yamada, Masataka Kudo, Junming Yue, Noriaki Sakuragi
PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value
Jianwei Xu, Guangbing Xiong, Zhe Cao, Hua Huang, Tianxiao Wang, Lei You, Li Zhou, Lianfang Zheng, Ya Hu, Taiping Zhang, Yupei Zhao
Inhibition of YAP suppresses CML cell proliferation and enhances efficacy of imatinib in vitro and in vivo
Hui Li, Zhenglan Huang, Miao Gao, Ningshu Huang, Zhenhong Luo, Huawei Shen, Xin Wang, Teng Wang, Jing Hu, Wenli Feng
Detection of ATM germline variants by the p53 mitotic centrosomal localization test in BRCA1/2-negative patients with early-onset breast cancer
Andrea Prodosmo, Amelia Buffone, Manlio Mattioni, Agnese Barnabei, Agnese Persichetti, Aurora De Leo, Marialuisa Appetecchia, Arianna Nicolussi, Anna Coppa, Salvatore Sciacchitano, Carolina Giordano, Paola Pinnarò, Giuseppe Sanguineti, Lidia Strigari, Gabriele Alessandrini, Francesco Facciolo, Maurizio Cosimelli, Gian Luca Grazi, Giacomo Corrado, Enrico Vizza, Giuseppe Giannini, Silvia Soddu
Reactivation of mutant p53 by capsaicin, the major constituent of peppers
Alessia Garufi, Giuseppa Pistritto, Mara Cirone, Gabriella D’Orazi
New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study
Chiara Tommasino, Lucrezia Gambardella, Maria Buoncervello, Roger J. Griffin, Bernard T. Golding, Manuela Alberton, Daniele Macchia, Massimo Spada, Bruna Cerbelli, Giulia d’Amati, Walter Malorni, Lucia Gabriele, Anna Maria Giammarioli
Alternative scheduling of pulsatile, high dose sunitinib efficiently suppresses tumor growth
Maria Rovithi, Richard R. de Haas, Richard J. Honeywell, Dennis Poel, Godefridus J. Peters, Arjan W. Griffioen, Henk M. W. Verheul
Oxidative stress in prostate hyperplasia and carcinogenesis
Udensi K. Udensi, Paul B. Tchounwou
Targeting interleukin-1 receptor-associated kinase 1 for human hepatocellular carcinoma
Ning Li, Jinhua Jiang, Jing Fu, Ting Yu, Bibo Wang, Wenhao Qin, An Xu, Mengchao Wu, Yao Chen, Hongyang Wang
Emerging role of epithelial-mesenchymal transition in hepatic cancer
Go J. Yoshida
Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression
Dong-liang Chen, Huai-qiang Ju, Yun-xin Lu, Le-zong Chen, Zhao-lei Zeng, Dong-sheng Zhang, Hui-yan Luo, Feng Wang, Miao-zhen Qiu, De-shen Wang, Da-zhi Xu, Zhi-wei Zhou, Helene Pelicano, Peng Huang, Dan Xie, Feng-hua Wang, Yu-hong Li, Rui-hua Xu
Tumoricidal efficacy coincides with CD11c up-regulation in antigen-specific CD8+ T cells during vaccine immunotherapy
Yohei Takeda, Masahiro Azuma, Misako Matsumoto, Tsukasa Seya
WNT5A signaling impairs breast cancer cell migration and invasion via mechanisms independent of the epithelial-mesenchymal transition
Chandra Prakash Prasad, Shivendra Kumar Chaurasiya, William Guilmain, Tommy Andersson
Demystifying the mechanistic and functional aspects of p21 gene activation with double-stranded RNAs in human cancer cells
Huan-Lei Wu, Sen-Mao Li, Jia Hu, Xiao Yu, Hua Xu, Zhong Chen, Zhang-Qun Ye
eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts
Cinzia Pisani, Annalisa Onori, Francesca Gabanella, Francesca Delle Monache, Antonella Borreca, Martine Ammassari-Teule, Maurizio Fanciulli, Maria Grazia Di Certo, Claudio Passananti, Nicoletta Corbi
Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells
Yuanmei Zhai, Jing Zhang, Hui Wang, Wei Lu, Sihong Liu, Yehua Yu, Wei Weng, Zhiyong Ding, Qi Zhu, Jun Shi
TIMP1 is a prognostic marker for the progression and metastasis of colon cancer through FAK-PI3K/AKT and MAPK pathway
Guohe Song, Shifeng Xu, Hong Zhang, Yupeng Wang, Chao Xiao, Tao Jiang, Leilei Wu, Tao Zhang, Xing Sun, Lin Zhong, Chongzhi Zhou, Zhaowen Wang, Zhihai Peng, Jian Chen, Xiaoliang Wang
Non-benzoquinone geldanamycin analogs trigger various forms of death in human breast cancer cells
Zhirui Zhang, Hong-Mei Li, Can Zhou, Qixiang Li, Linyan Ma, Zixuan Zhang, Yiming Sun, Lirong Wang, Xudong Zhang, Bing Zhu, Young-Soo Hong, Cheng-Zhu Wu, Hao Liu
Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer
Nirmala Jagadish, Sumit Agarwal, Namita Gupta, Rukhsar Fatima, Sonika Devi, Vikash Kumar, Vaishali Suri, Rajive Kumar, Vitusha Suri, Trilok Chand Sadasukhi, Anju Gupta, Abdul S. Ansari, Nirmal Kumar Lohiya, Anil Suri
Epidermal growth factor (EGF) receptor-ligand based molecular staging predicts prognosis in head and neck squamous cell carcinoma partly due to deregulated EGF- induced amphiregulin expression
Jian Gao, Camilla H. Ulekleiv, Trond S. Halstensen
RETRACTED ARTICLE: TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways
Run-Wei Yang, Ying-Yue Zeng, Wen-Ting Wei, Yan-Mei Cui, Hui-Ying Sun, Yue-Long Cai, Xin-Xin Nian, Yun-Teng Hu, Yu-Ping Quan, Sheng-Lu Jiang, Meng Wang, Ya-Li Zhao, Jun-Feng Qiu, Ming-Xuan Li, Jia-Huan Zhang, Mei-Rong He, Li Liang, Yan-Qing Ding, Wen-Ting Liao
Cell cycle checkpoint in cancer: a therapeutically targetable double-edged sword
Roberta Visconti, Rosa Della Monica, Domenico Grieco
Erratum to: Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin
Corina Buta, Eva Benabou, Marie Lequoy, Hélène Régnault, Dominique Wendum, Fatiha Merabtene, Hamza Chettouh, Lynda Aoudjehane, Filomena Conti, Yves Chrétien, Olivier Scatton, Olivier Rosmorduc, Françoise Praz, Laetitia Fartoux, Christèle Desbois-Mouthon
Development of a methodology for in vivo follow-up of hepatocellular carcinoma in hepatocyte specific Trim24-null mice treated with myo-inositol trispyrophosphate
Mihaela Ignat, Cherif Youssef Akladios, Véronique Lindner, Konstantin Khetchoumian, Marius Teletin, Didier Muttter, Pierre Marc Aprahamian, Jacques Marescaux
From pathogenesis to clinical application: insights into exosomes as transfer vectors in cancer
Wenting Xu, Zhen Yang, Nonghua Lu
Trends and advances in tumor immunology and lung cancer immunotherapy
Mohanad Aldarouish, Cailian Wang
LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC
Chengcheng Yang, Huangzhen Wang, Boxiang Zhang, Yimeng Chen, Yamin Zhang, Xin Sun, Guodong Xiao, Kejun Nan, Hong Ren, Sida Qin
Exosomes derived from HCC cells induce sorafenib resistance in hepatocellular carcinoma both in vivo and in vitro
Zhen Qu, Junhua Wu, Junyi Wu, Dongjun Luo, Chunping Jiang, Yitao Ding
Long non-coding RNA H19 regulates FOXM1 expression by competitively binding endogenous miR-342-3p in gallbladder cancer
Shou-Hua Wang, Fei Ma, Zhao-hui Tang, Xiao-Cai Wu, Qiang Cai, Ming-Di Zhang, Ming-Zhe Weng, Di Zhou, Jian-Dong Wang, Zhi-Wei Quan
Shock wave-induced ATP release from osteosarcoma U2OS cells promotes cellular uptake and cytotoxicity of methotrexate
Baochang Qi, Tiecheng Yu, Chengxue Wang, Tiejun Wang, Jihang Yao, Xiaomeng Zhang, Pengfei Deng, Yongning Xia, Wolfgang G. Junger, Dahui Sun
Over-expression of the long non-coding RNA HOTTIP inhibits glioma cell growth by BRE
Li-Min Xu, Lei Chen, Feng Li, Run Zhang, Zong-yang Li, Fan-Fan Chen, Xiao-Dan Jiang
Spheres derived from the human SN12C renal cell carcinoma cell line are enriched in tumor initiating cells
Yanhui Zhang, Baocun Sun, Xiulan Zhao, Huizhi Sun, Wei Cui, Zhiyong Liu, Xin Yao, Xueyi Dong
RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis
Wen-Juan Gan, Jing-Ru Wang, Xiao-Li Zhu, Xiao-Shun He, Peng-Da Guo, Shen Zhang, Xiu-Ming Li, Jian-Ming Li, Hua Wu
Leptin promotes epithelial-mesenchymal transition of breast cancer via the upregulation of pyruvate kinase M2
Lan Wei, Kuangfa Li, Xueli Pang, Bianqin Guo, Min Su, Yunxiu Huang, Nian Wang, Feihu Ji, Changli Zhong, Junhong Yang, Zhiqian Zhang, Yulin Jiang, Yifeng Liu, Tingmei Chen
The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells
S. Zappavigna, M. Scuotto, A. M. Cossu, D. Ingrosso, M. De Rosa, C. Schiraldi, R. Filosa, M. Caraglia
Enhanced stimulation of anti-breast cancer T cells responses by dendritic cells loaded with poly lactic-co-glycolic acid (PLGA) nanoparticle encapsulated tumor antigens
Soodabeh Iranpour, Vahid Nejati, Nowruz Delirezh, Pouria Biparva, Sadegh Shirian
A panel of four genes accurately differentiates benign from malignant thyroid nodules
Qing-Xuan Wang, En-Dong Chen, Ye-Feng Cai, Quan Li, Yi-Xiang Jin, Wen-Xu Jin, Ying-Hao Wang, Zhou-Ci Zheng, Lu Xue, Ou-Chen Wang, Xiao-Hua Zhang
Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer
Tian-Yu Liu, Jian Chen, Chun-Liang Shang, Hong-Wei Shen, Jia-Ming Huang, Yan-Chun Liang, Wei Wang, Yun-He Zhao, Duo Liu, Man Shu, Lu-Yan Guo, Zheng Hu, Shu-Zhong Yao
Efficacy and safety of aflibercept in in vitro and in vivo models of retinoblastoma
Dong Yoon Kim, Jeong A Choi, Jae-Young Koh, Young Hee Yoon
Hepatitis B virus X protein promotes interleukin-7 receptor expression via NF-κB and Notch1 pathway to facilitate proliferation and migration of hepatitis B virus-related hepatoma cells
Fanyun Kong, Wei Hu, Kai Zhou, Xiao Wei, Yanbo Kou, Hongjuan You, Kuiyang Zheng, Renxian Tang
Pathologically decreased expression of miR-193a contributes to metastasis by targeting WT1-E-cadherin axis in non-small cell lung cancers
Junjie Chen, Shenmeng Gao, Chunjing Wang, Zhonggai Wang, Huxiang Zhang, Kate Huang, Bin Zhou, Haiying Li, Zhijie Yu, Jianbo Wu, Chengshui Chen
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
Mahmoud Alhosin, Ziad Omran, Mazin A. Zamzami, Abdulrahman L. Al-Malki, Hani Choudhry, Marc Mousli, Christian Bronner
Galectin-1 from cancer-associated fibroblasts induces epithelial–mesenchymal transition through β1 integrin-mediated upregulation of Gli1 in gastric cancer
Yang Chong, Dong Tang, Qingquan Xiong, Xuetong Jiang, Chuanqi Xu, Yuqin Huang, Jie Wang, Huaicheng Zhou, Youquan Shi, Xiaoqing Wu, Daorong Wang
miR-589-5p inhibits MAP3K8 and suppresses CD90+ cancer stem cells in hepatocellular carcinoma
Xi Zhang, Peng Jiang, Ling Shuai, Kai Chen, Zhonghu Li, Yujun Zhang, Yan Jiang, Xiaowu Li
Upregulation of miR-501-5p activates the wnt/β-catenin signaling pathway and enhances stem cell-like phenotype in gastric cancer
Dongmei Fan, Baoqi Ren, Xiaojun Yang, Jia Liu, Zhengzheng Zhang
Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II
Huanli Xu, Qunying Chen, Hong Wang, Pingxiang Xu, Ru Yuan, Xiaorong Li, Lu Bai, Ming Xue
Use of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinic
Aniello Cerrato, Francesco Morra, Angela Celetti
HPV16 integration probably contributes to cervical oncogenesis through interrupting tumor suppressor genes and inducing chromosome instability
Jun-Wei Zhao, Fang Fang, Yi Guo, Tai-Lin Zhu, Yun-Yun Yu, Fan-Fei Kong, Ling-Fei Han, Dong-Sheng Chen, Fang Li
Hyaluronan synthase 2 expressed by cancer-associated fibroblasts promotes oral cancer invasion
Ziwen Zhang, Detao Tao, Ping Zhang, Xue Liu, Yuchao Zhang, Jie Cheng, Hua Yuan, Laikui Liu, Hongbing Jiang
Sirtuins in metabolism, DNA repair and cancer
Zhen Mei, Xian Zhang, Jiarong Yi, Junjie Huang, Jian He, Yongguang Tao
Antitumor activity of TY-011 against gastric cancer by inhibiting Aurora A, Aurora B and VEGFR2 kinases
Wang Liu, Yu Lu, Xiaoping Chai, Xiao Liu, Tong Zhu, Xihan Wu, Yanfen Fang, Xuan Liu, Xiongwen Zhang
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment
Jianlong Li, Jinquan Cai, Shihong Zhao, Kun Yao, Ying Sun, Yongli Li, Lingchao Chen, Ruiyan Li, Xiuwei Zhai, Junhe Zhang, Chuanlu Jiang
Erratum to: Detection of ATM germline variants by the p53 mitotic centrosomal localization test in BRCA1/2-negative patients with early-onset breast cancer
Andrea Prodosmo, Amelia Buffone, Manlio Mattioni, Agnese Barnabei, Agnese Persichetti, Aurora De Leo, Marialuisa Appetecchia, Arianna Nicolussi, Anna Coppa, Salvatore Sciacchitano, Carolina Giordano, Paola Pinnarò, Giuseppe Sanguineti, Lidia Strigari, Gabriele Alessandrini, Francesco Facciolo, Maurizio Cosimelli, Gian Luca Grazi, Giacomo Corrado, Enrico Vizza, Giuseppe Giannini, Silvia Soddu
Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer
Xiaohong Wang, Chengfeng Xu, Yitong Hua, Leitao Sun, Kai Cheng, Zhongming Jia, Yong Han, Jianli Dong, Yuzhen Cui, Zhenlin Yang
A novel long non-coding RNA lnc-GNAT1-1 is low expressed in colorectal cancer and acts as a tumor suppressor through regulating RKIP-NF-κB-Snail circuit
Chunxiang Ye, Zhanlong Shen, Bo Wang, Yansen Li, Tao Li, Yang Yang, Kewei Jiang, Yingjiang Ye, Shan Wang
MicroRNA-19b-3p regulates nasopharyngeal carcinoma radiosensitivity by targeting TNFAIP3/NF-κB axis
Teng Huang, Li Yin, Jing Wu, Jia-Jia Gu, Jian-Zhong Wu, Dan Chen, Hong-Liang Yu, Kai Ding, Nan Zhang, Ming-Yu Du, Lu-Xi Qian, Zhi-Wei Lu, Xia He
Patient-derived xenografts: a relevant preclinical model for drug development
Luca Pompili, Manuela Porru, Carla Caruso, Annamaria Biroccio, Carlo Leonetti
CCDC88A, a prognostic factor for human pancreatic cancers, promotes the motility and invasiveness of pancreatic cancer cells
Aki Tanouchi, Keisuke Taniuchi, Mutsuo Furihata, Seiji Naganuma, Ken Dabanaka, Masashi Kimura, Ryohei Watanabe, Takuhiro Kohsaki, Takahiro Shimizu, Motoaki Saito, Kazuhiro Hanazaki, Toshiji Saibara
srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer
Yuyang Feng, Lei Feng, Di Yu, Jian Zou, Zhaohui Huang
A piperazidine derivative of 23-hydroxy betulinic acid induces a mitochondria-derived ROS burst to trigger apoptotic cell death in hepatocellular carcinoma cells
Nan Yao, Ying-jie Li, Yu-he Lei, Nan Hu, Wei-Min Chen, Zhe Yao, Miao Yu, Jun-shan Liu, Wen-cai Ye, Dong-mei Zhang
Elaboration of a nomogram to predict nonsentinel node status in breast cancer patients with positive sentinel node, intraoperatively assessed with one step nucleic amplification: Retrospective and validation phase
Franco Di Filippo, Simona Di Filippo, Anna Maria Ferrari, Raffaele Antonetti, Alessandro Battaglia, Francesca Becherini, Laia Bernet, Renzo Boldorini, Catherine Bouteille, Simonetta Buglioni, Paolo Burelli, Rafael Cano, Vincenzo Canzonieri, Pierluigi Chiodera, Alfredo Cirilli, Luigi Coppola, Stefano Drago, Luca Di Tommaso, Privato Fenaroli, Roberto Franchini, Andrea Gianatti, Diana Giannarelli, Carmela Giardina, Florence Godey, Massimo M. Grassi, Giuseppe B. Grassi, Siobhan Laws, Samuele Massarut, Giuseppe Naccarato, Maria Iole Natalicchio, Sergio Orefice, Fabrizio Palmieri, Tiziana Perin, Manuela Roncella, Massimo G. Roncalli, Antonio Rulli, Angelo Sidoni, Corrado Tinterri, Maria C. Truglia, Isabella Sperduti