Journal of Interventional Cardiac Electrophysiology

Foreword neuromodulation for antiarrhythmic therapy

• Editorial

Tolga Aksu, Carlos A. Morillo, Juan C. Zerpa

Cardioneuroablation for the management of patients with recurrent vasovagal syncope and symptomatic bradyarrhythmias: the CNA-FWRD Registry

• CLINICAL TRIAL STUDY DESIGN

Tolga Aksu, Roderick Tung, Tom De Potter, Timothy M. Markman, Pasquale Santangeli, Jeanne du Fay de Lavallaz, Jeffrey R. Winterfield, Tina Baykaner, Daniel Alyesh, Jacqueline E. Joza, Rakesh Gopinathannair, Patrick Badertscher, Duc H. Do, Ayman Hussein, Jose Osorio, Thomas Dewland, Alexander Perino, Albert J. Rodgers, Christopher DeSimone, Alberto Alfie, Brett D. Atwater, David Singh, Kapil Kumar, Jonathan Salcedo, Jason S. Bradfield, Gaurav Upadhyay, Nitesh Sood, Parikshit S. Sharma, Sandeep Gautam, Vineet Kumar, Alexander Romeno Janner Dal Forno, Christopher E. Woods, Moshe Rav-Acha, Chiara Valeriano, Sunil Kapur, Andres Enriquez, Sri Sundaram, Michael Glikson, Edward Gerstenfeld, Jonathan Piccini, Wendy S. Tzou, William Sauer, Andre d’Avila, Kalyanam Shivkumar, Henry D. Huang

Cardioneuroablation for the treatment of vasovagal syncope and sinus bradycardia with atrial escape

• Case Reports

Tolga Aksu, Ferit Onur Mutluer, Henry Huang

Differential and synergistic effects of right and left atrial ganglionated plexi ablation in patients undergoing cardioneuroablation: results from the ELEGANCE multicenter study

• ORIGINAL RESEARCH

Pietro Francia, Daniel Viveros, Carlo Gigante, Giulio Falasconi, Diego Penela, David Soto-Iglesias, Federico Landra, Lucio Teresi, Julio Marti-Almor, José Alderete, Andrea Saglietto, Aldo Francisco Bellido, Dario Turturiello, Chiara Valeriano, Paula Franco-Ocaña, Fatima Zaraket, Maria Matiello, Juan Fernández-Armenta, Rodolfo San Antonio, Antonio Berruezo

Permanent pacing versus cardioneuroablation for cardioinhibitory vasovagal syncope

Rakesh Gopinathannair, Brian Olshansky, Mohit K. Turagam, Sandeep Gautam, Piotr Futyma, Krishna Akella, Halil Ibrahim Tanboga, Serdar Bozyel, Kivanc Yalin, Deepak Padmanabhan, Jayaprakash Shenthar, Dhanunjaya Lakkireddy, Tolga Aksu

Refractory malignant cardioinhibitory vasovagal syncope: should we pace or should we ablate?

• COMMENTARY

Juan Carlos Zerpa Acosta, Jose Carlos Pachon Mateos

Time for a paradigm shift: from pacing to ablation in reflex syncope

• LETTER

Rodolfo San Antonio

Stellate ganglia stimulation counteracts vagal stimulation by significantly increasing heart rate and blood pressure

Ammar M. Killu, Mei Yang, Niyada Naksuk, Jason Tri, Xuping Li, Roshini Asirvatham, Samuel J. Asirvatham, Yong-Mei Cha

The impact of the clinical diagnosis on the vagal response and heart rate after ganglionated plexus ablation

Tolga Aksu, Kivanc Yalin, Ferit Onur Mutluer, Kassem Farhat, Halil Ibrahim Tanboga, Sunny S. Po, Stavros Stavrakis

Cardioneuroablation for vasovagal syncope: How to move beyond “learning by burning”?

• Commentary

Dominik Linz, Stavros Stavrakis

Improved health-related quality of life after cardioneuroablation in patients with vasovagal syncope

Erkan Baysal, Ferit Onur Mutluer, Alara Ece Dagsali, Umur Cengiz Kumrulu, Henry D. Huang, Tolga Aksu

Quality of life improvement following cardioneuroablation for vasovagal syncope: expected or too early to say?

• COMMENTARY

Bosky Soni, Dhiraj Gupta, Rakesh Gopinathannair

The Efficacy of Cardioneuroablation versus Midodrine in Patients with Vasovagal Syncope: Design and Rationale for the CAMPAIGN Trial

• CLINICAL TRIAL STUDY DESIGN

Pakezhati Maimaitijiang, Bin Tu, Zihao Lai, Aiyue Chen, Zhuxin Zhang, Likun Zhou, Simin Cai, Lihui Zheng, Yan Yao

Diagnostic yield of head-up tilt table test in hypertrophic cardiomyopathy and unexplained syncope: the knot does not seem to be unraveling

• ORIGINAL RESEARCH

Serdar Bozyel, Faysal Şaylık, Nur Dalgıç, Abdülcebbar Şipal, Şükriye Ebru Önder, Metin Çağdaş, Tümer Erdem Güler, Carlos A. Morillo, Tolga Aksu

Post-procedural inappropriate sinus tachycardia after cardioneural ablation for malignant swallow syncope

• IMAGES IN ELECTROPHYSIOLOGY

Nikhila Chelikam, Aashish Katapadi, Naga Venkata K Pothineni, Rakesh Gopinathannair, Rajesh Kabra, Rangarao Tummala, Andrea Yang, Dhanunjaya Lakkireddy, Douglas Darden

Cardioneuroablation for the management of neurally mediated syncope, sinus bradycardia, and atrioventricular block

• REVIEWS

Jamario Skeete, Jonathan S. Gordon, Lincoln Kavinksy, Henry D. Huang, Tolga Aksu

Vagal AF induction test (VAFIT): a new endpoint for optimizing atrial fibrillation ablation through cardioneuroablation

• INVITED RESEARCH

Jose Carlos Pachon-M, Enrique I. Pachon-M, Tomas G. Santillana-P, Tasso J. Lobo, Carlos Thiene C. Pachon, Juan Carlos Pachon-M, Maria Zelia C. Pachon, John Clark

Feasibility of mapping and ablating ectopy-triggering ganglionated plexus reproducibly in persistent atrial fibrillation

• Open Access

Clare Coyle, Simos Koutsoftidis, Min-Young Kim, Bradley Porter, Daniel Keene, Vishal Luther, Balvinder Handa, Jamie Kay, Elaine Lim, Louisa Malcolme-Lawes, Michael Koa-Wing, Phang Boon Lim, Zachary I. Whinnett, Fu Siong Ng, Norman Qureshi, Nicholas S. Peters, Nicholas W. F. Linton, Emmanuel Drakakis, Prapa Kanagaratnam

Variability of baroreceptor reflex assessed by tilt table test in a patient undergoing pulmonary vein isolation

• Open Access

Anna Zuk, Roman Piotrowski, Agnieszka Sikorska, Ilona Kowalik, Piotr Kulakowski, Jakub Baran

Baroreceptor reflex after pulmonary vein isolation assessed by tilt table test: adding another piece to the puzzle

• COMMENTARY

Irina Mustafina, Stavros Stavrakis

Incidental ablation of ganglionated plexus during atrial fibrillation ablation

• Open Access
• ORIGINAL RESEARCH

Stephen Keane, Darshak Patel, Brian Otto, Lily Englander, Ramanan Kumareswaran, David Lin, Michael P. Riley, Saman Nazarian, Francis E. Marchlinski, Timothy M. Markman

Reduction in atrial and ventricular electrical heterogeneity following pulmonary vein isolation in patients with atrial fibrillation

Guilherme L. Fialho, Bruce D. Nearing, Jonathan W. Waks, Timothy R. Maher, John-Ross Clarke, Alyssa Shepherd, Andre D’Avila, Richard L. Verrier

A comparative meta-analysis of addition of ganglionic plexus ablation versus no ganglionic plexus ablation to pulmonary vein isolation for atrial fibrillation

• RESEARCH LETTER

Ashish Kumar, Mariam Shariff, Jose Carlos Pachon, Juan C. Zerpa Acosta, Christopher V. DeSimone, John Stulak, Malini Madhavan, Abhishek J. Deshmukh, Gurukripa N. Kowlgi

Ganglionated plexus ablation and pulmonary vein isolation: the future of AF ablation

• Commentary

Min-Young Kim, Tolga Aksu

Different time course effect of autonomic nervous modulation after cryoballoon and hotballoon catheter ablations for paroxysmal atrial fibrillation

Noriyuki Suzuki, Yasuya Inden, Satoshi Yanagisawa, Yuuki Shimizu, Shingo Narita, Kei Hiramatsu, Ryota Yamauchi, Ryo Watanabe, Naoki Tsurumi, Masafumi Shimojo, Kazumasa Suga, Yukiomi Tsuji, Rei Shibata, Toyoaki Murohara

Incidental parasympathetic cardiac denervation during atrial fibrillation ablation using high power short duration: a marker of long-term success

Fabricio Vassallo, Lucas Corcino, Christiano Cunha, Eduardo Serpa, Carlos Lovatto, Aloyr Simoes Jr., Hermes Carloni, Dalton Hespanhol, Dalbian Gasparini, Luiz Fernando Barbosa, Andre Schmidt

Neuromodulation for ventricular arrhythmias: progress—but are we there yet?

• COMMENTARY

Henry D. Huang, Tolga Aksu, Jeffrey Winterfield

Cardiac sympathetic denervation for untreatable ventricular tachycardia in structural heart disease. Strengths and pitfalls of evolving surgical techniques

Filippo Maria Cauti, Silvia Capone, Pietro Rossi, Marco Polselli, Federico Venuta, Jacopo Vannucci, Katia Bruno, Francesco Pugliese, Pierfrancesco Tozzi, Stefano Bianchi, Marco Anile, Raffaele Quaglione, Daniele Diso, Tiziano De Giacomo, Camilla Poggi, Ylenia Pecoraro, Carolina Carillo, Massimiliano Bassi, Davide Amore, Enrico Mottola, Martina Bianco, Francesco Ferrante, Rita Sousa Vaz Ferrara, Gioacchino Galardo, Andrea Del Bianco, Giordano Giovanni, Matteo Brisciani, Mario Piazzolla, Veronica Zullino, Franco Ruberto, Dalila De Paolo

Modified sympathicotomy in patients with refractory ventricular tachycardia and structural heart disease: a single-center experience

Filippo Maria Cauti, Pietro Rossi, Stefano Bianchi, Michele Magnocavallo, Silvia Capone, Domenico Giovanni Della Rocca, Marco Polselli, Katia Bruno, Pierfrancesco Tozzi, Chiara Rossi, Jacopo Vannucci, Francesco Pugliese, Raffaele Quaglione, Federico Venuta, Marco Anile

Cardiac sympathetic modulation: searching for a simplified approach

• COMMENTARY

Mohamad Raad, Timothy M. Markman

Unicentric Brazilian registry of cardiac sympathetic denervation for control of ventricular arrhythmias

• RESEARCH LETTER

Rodrigo M. Kulchetscki, Paulo Henrique Peitl Gregório, Gabrielle D.’Arezzo Pessente, Cristiano F. Pisani, Muhieddine O. Chokr, Carina A. Hardy, Luciana Sacilotto, Francisco Carlos da Costa Darrieux, Denise Hachul, Mauricio I. Scanavacca, Paulo M. Pêgo-Fernandes

Safety and outcomes of surgical cardiac sympathetic denervation when used as salvage therapy among high-risk patients with refractory ventricular arrhythmias

• RESEARCH LETTER

Brett Curtis, Gabriella VanAken, Mohammed Al-Sadawi, Hamid Emami, William R. Lynch, Amrish Deshmukh, Michael Ghannam, Rakesh Latchamsetty, Frank Bogun, Jackson J. Liang

The role of cardiac sympathetic denervation for ventricular arrhythmias: an updated systematic review and meta-analysis

• ORIGINAL RESEARCH

Daniel B. Hanna, Ahmadreza Karimianpour, Nicole Mamprejew, Chris Fiechter, Dhiran Verghese, Viviana Navas, Dinesh Sharma

Stellate ganglion block for refractory ventricular arrhythmias: an updated systematic review

• RESEARCH LETTER

Yong Hao Yeo, Jia Yean Thong, Min-Choon Tan, Justin Z. Lee, Jian Liang Tan, Timothy Markman, Pattara Rattanawong

Cardioneural ablation—the first case series without the use of fluoroscopy

• ORIGINAL RESEARCH

Daniel Alyesh, Nicholas Palmeri, Benjamin Jones, Samantha Hanslip, William Choe, Sri Sundaram

Intracardiac echocardiography and electroanatomical mapping: do we still need fluoroscopy for cardioneuroablation procedures?

• COMMENTARY

Tolga Aksu, Henry D. Huang

Fluoroscopy-free cardioneuroablation for functional bradycardia: a single-center experience

• ORIGINAL RESEARCH

Parnia Abolhassan Choubdar, Megan Gruber, Jose Carlos Pachon-M, Stephen Manu, Mansour Razminia, John Clark

Short-term deceleration capacity: a novel non-invasive indicator of parasympathetic activity in patients undergoing pulmonary vein isolation

• Open Access
• ORIGINAL RESEARCH

Łukasz Zarębski, Piotr Futyma

Cardiac deceleration capacity: do we have a new indicator for pulmonary vein isolation?

• COMMENTARY

Tolga Aksu, Henry D. Huang

Targeted ablation of epicardial ganglionated plexi during cardiac surgery with pulsed field electroporation (NEURAL AF)

• Open Access

Daniel R. Musikantow, Vivek Y. Reddy, Ivo Skalsky, Tamaz Shaburishvili, Martin van Zyl, Barry O’Brien, Ken Coffey, John Reilly, Petr Neuzil, Samuel Asirvatham, Joris R. de Groot

Redefining cardiac care: the promising horizon of epicardial pulse field ablation for postoperative atrial fibrillation

• INVITED COMMENTARY

Juan Carlos Zerpa Acosta, Gurukripa N. Kowlgi

Focal pulsed field ablation for guiding and assessing the acute effect of cardioneuroablation

• Open Access

Ivan Sikiric, Zrinka Jurisic, Toni Breskovic, Marina Juric-Paic, Nina Berovic, Josip Kedzo, Ivan Pletikosic, Tolga Aksu, Ante Anic

Step-by-step application of a new ganglionated plexus mapping method in a patient with vasovagal syncope

• TECHNICAL REPORT

Şükriye Ebru Önder, Tümer Erdem Güler, Serdar Bozyel, Nur Dalgıç, Abdülcebbar Şipal, Metin Çağdaş, Emre Kılıç, Henry Huang, Tolga Aksu