Ausgabe 1/2008
Inhalt (53 Artikel)
Does gamma-aminobutyric acid (GABA) influence the development of chronic inflammation in rheumatoid arthritis?
James M Kelley, Laura B Hughes, S Louis Bridges Jr
Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration
Edward L Tobinick, Hyman Gross
Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt
Bin Xing, Tao Xin, Randy Lee Hunter, Guoying Bing
Complement anaphylatoxin C5a neuroprotects through regulation of glutamate receptor subunit 2 in vitro and in vivo
Piali Mukherjee, Sunil Thomas, Giulio Maria Pasinetti
Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease
Jian Luo, Peggy Ho, Lawrence Steinman, Tony Wyss-Coray
The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective
Solomon S Shaftel, W Sue T Griffin, M Kerry O'Banion
Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease
James B Koprich, Casper Reske-Nielsen, Prabhakar Mithal, Ole Isacson
Plaque complement activation and cognitive loss in Alzheimer's disease
David A Loeffler, Dianne M Camp, David A Bennett
Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment
Liya Qin, Jun He, Richard N Hanes, Olivera Pluzarev, Jau-Shyong Hong, Fulton T Crews
Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2
Kiyomi Takahashi, Nobuaki Funata, Fusahiro Ikuta, Shigehiro Sato
Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease
Xuesong Chen, Jeremy W Gawryluk, John F Wagener, Othman Ghribi, Jonathan D Geiger
Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid
Kathryn E Nichol, Wayne W Poon, Anna I Parachikova, David H Cribbs, Charles G Glabe, Carl W Cotman
The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection
Thi A Tran, Melissa K McCoy, Michael B Sporn, Malú G Tansey
Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
Christopher J Henry, Yan Huang, Angela Wynne, Mark Hanke, Justin Himler, Michael T Bailey, John F Sheridan, Jonathan P Godbout
Persistent Borna Disease Virus (BDV) infection activates microglia prior to a detectable loss of granule cells in the hippocampus
Mikhail V Ovanesov, Krisztina Moldovan, Kimberly Smith, Michael W Vogel, Mikhail V Pletnikov
Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2
Saba Aid, Robert Langenbach, Francesca Bosetti
VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult
Jae K Ryu, James G McLarnon
Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease
Alexander Harkavyi, Amjad Abuirmeileh, Rebecca Lever, Ann E Kingsbury, Christopher S Biggs, Peter S Whitton
Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis
Andre M Mueller, Xiomara Pedré, Thomas Stempfl, Ingo Kleiter, Sebastien Couillard-Despres, Ludwig Aigner, Gerhard Giegerich, Andreas Steinbrecher
Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity
Dan Zhang, Xiaoming Hu, Sung-Jen Wei, Jie Liu, Huiming Gao, Li Qian, Belinda Wilson, Gengtao Liu, Jau-Shyong Hong
Neuromyelitis optica pathogenesis and aquaporin 4
David J Graber, Michael Levy, Douglas Kerr, William F Wade
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
Jing-Ji Jin, Hong-Duck Kim, J Adam Maxwell, Ling Li, Ken-ichiro Fukuchi
GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice
Longxuan Li, Jun Liu, William Z Suo
Interactions between APP secretases and inflammatory mediators
Magdalena Sastre, Jochen Walter, Steve M Gentleman
Characterization of early and terminal complement proteins associated with polymorphonuclear leukocytes in vitro and in vivo after spinal cord injury
Hal X Nguyen, Manuel D Galvan, Aileen J Anderson
Evidence of platelet activation in multiple sclerosis
William A Sheremata, Wenche Jy, Lawrence L Horstman, Yeon S Ahn, J Steven Alexander, Alireza Minagar
Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury
Eric Lloyd, Kathleen Somera-Molina, Linda J Van Eldik, D Martin Watterson, Mark S Wainwright
Transient middle cerebral artery occlusion induces microglial priming in the lumbar spinal cord: a novel model of neuroinflammation
Katie Moisse, Ian Welch, Tracy Hill, Kathryn Volkening, Michael J Strong
Histoplasma capsulatum yeast phase-specific protein Yps3p induces Toll-like receptor 2 signaling
Rajagopal N Aravalli, Shuxian Hu, Jon P Woods, James R Lokensgard
Acute hemorrhagic demyelination in a murine model of multiple sclerosis
Istvan Pirko, Georgette L Suidan, Moses Rodriguez, Aaron J Johnson
Immune modulation and increased neurotrophic factor production in multiple sclerosis patients treated with testosterone
Stefan M Gold, Sara Chalifoux, Barbara S Giesser, Rhonda R Voskuhl
P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis
Anthony J Sharp, Paul E Polak, Vittoria Simonini, Shao X Lin, Jill C Richardson, Ernesto R Bongarzone, Douglas L Feinstein
Delayed administration of a matrix metalloproteinase inhibitor limits progressive brain injury after hypoxia-ischemia in the neonatal rat
Christopher C Leonardo, Autumn K Eakin, Joanne M Ajmo, Lisa A Collier, Keith R Pennypacker, Alex Y Strongin, Paul E Gottschall
MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult
Wendy L Thompson, William J Karpus, Linda J Van Eldik
Association of alleles carried at TNFA -850 and BAT1-22 with Alzheimer's disease
Anastazija Gnjec, Katarzyna J D'Costa, Simon M Laws, Ross Hedley, Kelvin Balakrishnan, Kevin Taddei, Georgia Martins, Athena Paton, Giuseppe Verdile, Samuel E Gandy, G Anthony Broe, William S Brooks, Hayley Bennett, Olivier Piguet, Patricia Price, Judith Miklossy, Joachim Hallmayer, Patrick L McGeer, Ralph N Martins
Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation
Jae Woong Lee, Yong Kyung Lee, Dong Yeon Yuk, Dong Young Choi, Sang Bae Ban, Ki Wan Oh, Jin Tae Hong
Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism
Alexander Semmler, Sven Hermann, Florian Mormann, Marc Weberpals, Stephan A Paxian, Thorsten Okulla, Michael Schäfers, Markus P Kummer, Thomas Klockgether, Michael T Heneka
Corticosteroids reverse cytokine-induced block of survival and differentiation of oligodendrocyte progenitor cells from rats
Stefan A Mann, Beatrix Versmold, Romy Marx, Sabine Stahlhofen, Irmgard D Dietzel, Rolf Heumann, Richard Berger
Persisting atypical and cystic forms of Borrelia burgdorferiand local inflammation in Lyme neuroborreliosis
Judith Miklossy, Sandor Kasas, Anne D Zurn, Sherman McCall, Sheng Yu, Patrick L McGeer
Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression
Kavon Rezai-Zadeh, Jared Ehrhart, Yun Bai, Paul R Sanberg, Paula Bickford, Jun Tan, R Douglas Shytle
Mannan-Abeta28conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice
Irina Petrushina, Anahit Ghochikyan, Mikayel Mkrtichyan, Grigor Mamikonyan, Nina Movsesyan, Rodmehr Ajdari, Vitaly Vasilevko, Adrine Karapetyan, Andrew Lees, Michael G Agadjanyan, David H Cribbs
Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway
Teresa F Pais, Catarina Figueiredo, Rui Peixoto, Maria H Braz, Sukalyan Chatterjee
Hematopoietic cell activation in the subventricular zone after Theiler's virus infection
Gwendolyn E Goings, Adriana Greisman, Rachel E James, Leanne KF Abram, Wendy Smith Begolka, Stephen D Miller, Francis G Szele
TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
Melissa K McCoy, Malú G Tansey
Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice
Bettina H Clausen, Kate L Lambertsen, Alicia A Babcock, Thomas H Holm, Frederik Dagnaes-Hansen, Bente Finsen
Focal cerebral ischemia in the TNFalpha-transgenic rat
L Creed Pettigrew, Mark S Kindy, Stephen Scheff, Joe E Springer, Richard J Kryscio, Yizhao Li, David S Grass
Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection
Gretchen Hermes, James W Ajioka, Krystyna A Kelly, Ernest Mui, Fiona Roberts, Kristen Kasza, Thomas Mayr, Michael J Kirisits, Robert Wollmann, David JP Ferguson, Craig W Roberts, Jong-Hee Hwang, Toria Trendler, Richard P Kennan, Yasuhiro Suzuki, Catherine Reardon, William F Hickey, Lieping Chen, Rima McLeod
Kinin B2receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice
Adriana C Dos Santos, Ester Roffê, Rosa ME Arantes, Luiz Juliano, Jorge L Pesquero, João B Pesquero, Michael Bader, Mauro M Teixeira, Juliana Carvalho-Tavares
Astrocytes play a key role in activation of microglia by persistent Borna disease virus infection
Mikhail V Ovanesov, Yavuz Ayhan, Candie Wolbert, Krisztina Moldovan, Christian Sauder, Mikhail V Pletnikov
Inflammaging as a prodrome to Alzheimer's disease
Brian Giunta, Francisco Fernandez, William V Nikolic, Demian Obregon, Elona Rrapo, Terrence Town, Jun Tan
Impact of innate immunity in a subset of children with autism spectrum disorders: a case control study
Harumi Jyonouchi, Lee Geng, Agnes Cushing-Ruby, Huma Quraishi
Expression and distribution of Toll-like receptors 11–13 in the brain during murine neurocysticercosis
Bibhuti B Mishra, Uma Mahesh Gundra, Judy M Teale