Ausgabe 1/2012
Inhalt (280 Artikel)
Innate Immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1)
Pascal F Durrenberger, Anna Ettorre, Fatemah Kamel, Louise V Webb, Malcolm Sim, Richard S Nicholas, Omar Malik, Richard Reynolds, Rosemary J Boyton, Daniel M Altmann
NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration
Liya Qin, Fulton T Crews
Systemic administration of urocortin after intracerebral hemorrhage reduces neurological deficits and neuroinflammation in rats
Hock-Kean Liew, Cheng-Yoong Pang, Chih-Wei Hsu, Mei-Jen Wang, Ting-Yi Li, Hsiao-Fen Peng, Jon-Son Kuo, Jia-Yi Wang
Constitutive activity of NF-kappa B in myeloid cells drives pathogenicity of monocytes and macrophages during autoimmune neuroinflammation
Gisa Ellrichmann, Jan Thöne, De-Hyung Lee, Rudolph A Rupec, Ralf Gold, Ralf A Linker
Immunological characterization and transcription profiling of peripheral blood (PB) monocytes in children with autism spectrum disorders (ASD) and specific polysaccharide antibody deficiency (SPAD): case study
Harumi Jyonouchi, Lee Geng, Deanna L Streck, Gokce A Toruner
Activation of TRPV1 by capsaicin induces functional Kinin B1 receptor in rat spinal cord microglia
Sébastien Talbot, Jenny Pena Dias, Karim Lahjouji, Maurício Reis Bogo, Maria Martha Campos, Pierrette Gaudreau, Réjean Couture
Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia
Antonio CP de Oliveira, Eduardo Candelario-Jalil, Julia Langbein, Lena Wendeburg, Harsharan S Bhatia, Johannes CM Schlachetzki, Knut Biber, Bernd L Fiebich
Psychological stress in adolescent and adult mice increases neuroinflammation and attenuates the response to LPS challenge
Christopher J Barnum, Thaddeus WW Pace, Fang Hu, Gretchen N Neigh, Malú G Tansey
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
Sven Jarius, Klemens Ruprecht, Brigitte Wildemann, Tania Kuempfel, Marius Ringelstein, Christian Geis, Ingo Kleiter, Christoph Kleinschnitz, Achim Berthele, Johannes Brettschneider, Kerstin Hellwig, Bernhard Hemmer, Ralf A Linker, Florian Lauda, Christoph A Mayer, Hayrettin Tumani, Arthur Melms, Corinna Trebst, Martin Stangel, Martin Marziniak, Frank Hoffmann, Sven Schippling, Jürgen H Faiss, Oliver Neuhaus, Barbara Ettrich, Christian Zentner, Kersten Guthke, Ulrich Hofstadt-van Oy, Reinhard Reuss, Hannah Pellkofer, Ulf Ziemann, Peter Kern, Klaus P Wandinger, Florian Then Bergh, Tobias Boettcher, Stefan Langel, Martin Liebetrau, Paulus S Rommer, Sabine Niehaus, Christoph Münch, Alexander Winkelmann, Uwe K Zettl U, Imke Metz, Christian Veauthier, Jörn P Sieb, Christian Wilke, Hans P Hartung, Orhan Aktas, Friedemann Paul
CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis
Monica Roy, Jean-François Richard, Aline Dumas, Luc Vallières
Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?
Yannick Marchalant, Kevin Baranger, Gary L Wenk, Michel Khrestchatisky, Santiago Rivera
Endotoxin-induced cytokine and chemokine expression in the HIV-1 transgenic rat
Natasha F Homji, Xin Mao, Erik F Langsdorf, Sulie L Chang
IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci
Eunyoung Lee, Sarah Chanamara, David Pleasure, Athena M Soulika
Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice
Ana María Martín-Moreno, Begoña Brera, Carlos Spuch, Eva Carro, Luis García-García, Mercedes Delgado, Miguel A Pozo, Nadia G Innamorato, Antonio Cuadrado, María L de Ceballos
Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice
Ellinor Kenne, Anna Erlandsson, Lennart Lindbom, Lars Hillered, Fredrik Clausen
Erratum to: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats
Jagadeesh Sridhara Rao, Hyung-Wook Kim, Matthew Kellom, Dede Greenstein, Mei Chen, Andrew David Kraft, Gaylia Jean Harry, Stanley Isaac Rapoport, Mireille Basselin
Selective targeting of microglia by quantum dots
S Sakura Minami, Binggui Sun, Ketul Popat, Tiina Kauppinen, Mike Pleiss, Yungui Zhou, Michael E Ward, Paul Floreancig, Lennart Mucke, Tejal Desai, Li Gan
Neuroprotective function for ramified microglia in hippocampal excitotoxicity
Jonathan Vinet, Hilmar RJ van Weering, Annette Heinrich, Roland E Kälin, Anja Wegner, Nieske Brouwer, Frank L Heppner, Nico van Rooijen, Hendrikus WGM Boddeke, Knut Biber
Electroacupuncture pretreatment attenuates cerebral ischemic injury through α7 nicotinic acetylcholine receptor-mediated inhibition of high-mobility group box 1 release in rats
Qiang Wang, Feng Wang, Xin Li, Qianzi Yang, Xuying Li, Ning Xu, Yi Huang, Qiaomei Zhang, Xingchun Gou, Shaoyang Chen, Lize Xiong
Japanese encephalitis virus induces matrix metalloproteinase-9 expression via a ROS/c-Src/PDGFR/PI3K/Akt/MAPKs-dependent AP-1 pathway in rat brain astrocytes
Chuen-Mao Yang, Chih-Chung Lin, I-Ta Lee, Yi-Hsin Lin, Caleb M Yang, Wei-June Chen, Mei-Jie Jou, Li-Der Hsiao
TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation
Karim Belarbi, Timothy Jopson, David Tweedie, Carla Arellano, Weiming Luo, Nigel H Greig, Susanna Rosi
Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis
Muriel Tahtouh, Annelise Garçon-Bocquet, Françoise Croq, Jacopo Vizioli, Pierre-Eric Sautière, Christelle Van Camp, Michel Salzet, Patricia Nagnan-le Meillour, Joël Pestel, Christophe Lefebvre
Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat
Chun-Mei Xia, Melisa A Gulick, Sharon J Yu, John R Grider, Karnam S Murthy, John F Kuemmerle, Hamid I Akbarali, Li-Ya Qiao
Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor
Joana C d’Avila, Tina I Lam, Deborah Bingham, Jian Shi, Seok Joon Won, Tiina M Kauppinen, Stephen Massa, Jialing Liu, Raymond A Swanson
CCL2 upregulation triggers hypoxic preconditioning-induced protection from stroke
Ann M Stowe, Bradley K Wacker, Petra D Cravens, Jennifer L Perfater, Min K Li, Ruilong Hu, Angela B Freie, Olaf Stüve, Jeffrey M Gidday
Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease
Pablo Garrido-Gil, Belen Joglar, Ana I Rodriguez-Perez, Maria J Guerra, Jose L Labandeira-Garcia
Exacerbation of experimental autoimmune encephalomyelitis in prion protein (PrPc)-null mice: evidence for a critical role of the central nervous system
Pauline Gourdain, Clara Ballerini, Arnaud B Nicot, Claude Carnaud
Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91 phox subunit of NADPH oxidase
Qingshan Wang, Hui Zhou, Huiming Gao, Shih-Heng Chen, Chun-Hsien Chu, Belinda Wilson, Jau-Shyong Hong
Functional analysis of Pro-inflammatory properties within the cerebrospinal fluid after subarachnoid hemorrhage in vivo and in vitro
Ulf C Schneider, Jennifer Schiffler, Nahid Hakiy, Peter Horn, Peter Vajkoczy
A functional variant in promoter region of platelet-derived growth factor-D is probably associated with intracerebral hemorrhage
Yongyi Bai, Jingzhou Chen, Kai Sun, Yibo Wang, Rutai Hui
Concurrent multiple sclerosis and amyotrophic lateral sclerosis: where inflammation and neurodegeneration meet?
Grace Li, Margaret M Esiri, Olaf Ansorge, Gabriele C DeLuca
5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-γ-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability
Jee Hoon Lee, Hyunmi Kim, Joo Hong Woo, Eun-hye Joe, Ilo Jou
CD4+ CD25+ FoxP3+ regulatory T cells suppress cytotoxicity of CD8+ effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level
Kerstin Göbel, Stefan Bittner, Nico Melzer, Susann Pankratz, Angela Dreykluft, Michael K Schuhmann, Sven G Meuth, Heinz Wiendl
Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury
Kimberly R Byrnes, David J Loane, Bogdan A Stoica, Jiangyang Zhang, Alan I Faden
Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice
Alexander Rodriguez Guerrero, Kenzo Uchida, Hideaki Nakajima, Shuji Watanabe, Masaya Nakamura, William EB Johnson, Hisatoshi Baba
The cytokine tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 have a neuroprotective effect in the central nervous system
Ramiro Echeverry, Fang Wu, Woldeab B Haile, Jialing Wu, Manuel Yepes
Tumor necrosis factor-α-mediated threonine 435 phosphorylation of p65 nuclear factor-κB subunit in endothelial cells induces vasogenic edema and neutrophil infiltration in the rat piriform cortex following status epilepticus
Ji-Eun Kim, Hea Jin Ryu, Soo Young Choi, Tae-Cheon Kang
Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease
Shih-Yuan Chen, Ta-Fu Chen, Liang-Chuan Lai, Jen-Hau Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen
Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α
Caterina Scuderi, Marta Valenza, Claudia Stecca, Giuseppe Esposito, Maria Rosaria Carratù, Luca Steardo
Acetate supplementation modulates brain histone acetylation and decreases interleukin-1β expression in a rat model of neuroinflammation
Mahmoud L Soliman, Mark D Smith, Heidi M Houdek, Thad A Rosenberger
Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models
Young-Jung Lee, Dong-Young Choi, Im Seop Choi, Ki Ho Kim, Young Hee Kim, Hwan Mook Kim, Kiho Lee, Won Gil Cho, Jea Kyung Jung, Sang Bae Han, Jin-Yi Han, Sang-Yoon Nam, Young Won Yun, Jae Hwang Jeong, Ki-Wan Oh, Jin Tae Hong
Regulator of calcineurin 1 (Rcan1) has a protective role in brain ischemia/reperfusion injury
Mónica Sobrado, Belén G Ramirez, Fernando Neria, Ignacio Lizasoain, Maria Lourdes Arbones, Takashi Minami, Juan Miguel Redondo, María Ángeles Moro, Eva Cano
Therapeutic targeting of Krüppel-like factor 4 abrogates microglial activation
Deepak Kumar Kaushik, Rupanjan Mukhopadhyay, Kanhaiya Lal Kumawat, Malvika Gupta, Anirban Basu
Morphological features of microglial cells in the hippocampal dentate gyrus of Gunn rat: a possible schizophrenia animal model
Kristian Liaury, Tsuyoshi Miyaoka, Toshiko Tsumori, Motohide Furuya, Rei Wake, Masa Ieda, Keiko Tsuchie, Michiyo Taki, Kotomi Ishihara, Andi Jayalangkara Tanra, Jun Horiguchi
NOV/CCN3 attenuates inflammatory pain through regulation of matrix metalloproteinases-2 and -9
Lara Kular, Cyril Rivat, Brigitte Lelongt, Claire Calmel, Maryvonne Laurent, Michel Pohl, Patrick Kitabgi, Stéphane Melik-Parsadaniantz, Cécile Martinerie
Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways
Norbert Zilka, Zuzana Kazmerova, Santosh Jadhav, Peter Neradil, Aladar Madari, Dominika Obetkova, Ondrej Bugos, Michal Novak
The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury
Ryoji Tauchi, Shiro Imagama, Takamitsu Natori, Tomohiro Ohgomori, Akio Muramoto, Ryuichi Shinjo, Yukihiro Matsuyama, Naoki Ishiguro, Kenji Kadomatsu
Leukotrienes inhibit early stages of HIV-1 infection in monocyte-derived microglia-like cells
Jonathan Bertin, Corinne Barat, Dave Bélanger, Michel J Tremblay
Involvement of metabotropic glutamate receptor 5, AKT/PI3K Signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes
Ankit Shah, Peter S Silverstein, Dhirendra P Singh, Anil Kumar
Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage
Sen Lin, Qing Yin, Qi Zhong, Feng-Lin Lv, Yu Zhou, Jing-Qi Li, Jing-Zhou Wang, Bing-yin Su, Qing-Wu Yang
Targeting of prion-infected lymphoid cells to the central nervous system accelerates prion infection
Yael Friedman-Levi, Romana Hoftberger, Herbert Budka, Tehila Mayer-Sonnenfeld, Oded Abramsky, Haim Ovadia, Ruth Gabizon
DQB1*0602 rather than DRB1*1501 confers susceptibility to multiple sclerosis-like disease induced by proteolipid protein (PLP)
Nathali Kaushansky, Daniel M Altmann, Chella S David, Hans Lassmann, Avraham Ben-Nun
A hematopoietic contribution to microhemorrhage formation during antiviral CD8 T cell-initiated blood-brain barrier disruption
Holly L Johnson, Yi Chen, Georgette L Suidan, Jeremiah R McDole, Anne K Lohrey, Lisa M Hanson, Fang Jin, Istvan Pirko, Aaron J Johnson
Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology
Maria Teresa Ferretti, Simon Allard, Vanessa Partridge, Adriana Ducatenzeiler, A Claudio Cuello
Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury
Atsushi Sato, Hirokazu Ohtaki, Tomomi Tsumuraya, Dandan Song, Kenji Ohara, Masahide Asano, Yoichiro Iwakura, Takashi Atsumi, Seiji Shioda
The NAMPT inhibitor FK866 reverts the damage in spinal cord injury
Emanuela Esposito, Daniela Impellizzeri, Emanuela Mazzon, Gohar Fakhfouri, Reza Rahimian, Cristina Travelli, Gian Cesare Tron, Armando A Genazzani, Salvatore Cuzzocrea
Microglial TIR-domain-containing adapter-inducing interferon-β (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-κB
Sen Lin, Yajie Liang, Jiqiang Zhang, Chen Bian, Hongli Zhou, Qiang Guo, Ying Xiong, Shurong Li, Bingyin Su
High serum levels of transforming growth factor β1 are associated with increased cortical thickness in cingulate and right frontal areas in healthy subjects
Fabrizio Piras, Francesca Salani, Paola Bossù, Carlo Caltagirone, Gianfranco Spalletta
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia
Peter Röhnert, Werner Schmidt, Patrick Emmerlich, Alexander Goihl, Sabine Wrenger, Ute Bank, Karsten Nordhoff, Michael Täger, Siegfried Ansorge, Dirk Reinhold, Frank Striggow
A lack of association between elevated serum levels of S100B protein and autoimmunity in autistic children
Laila Yousef Al-Ayadhi, Gehan Ahmed Mostafa
Anti-inflammatory recombinant TSG-6 stabilizes the progression of focal retinal degeneration in a murine model
Jingsheng Tuo, Xiaoguang Cao, Defen Shen, Yujuan Wang, Jun Zhang, Joo Youn Oh, Darwin J Prockop, Chi-Chao Chan
Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain
Charles L Howe, Reghann G LaFrance-Corey, Rhianna S Sundsbak, Stephanie J LaFrance
The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function
Elizabeth Gray, Mark Ginty, Kevin Kemp, Neil Scolding, Alastair Wilkins
Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α
Emanuela Esposito, Barbara Rinaldi, Emanuela Mazzon, Maria Donniacuo, Daniela Impellizzeri, Irene Paterniti, Annalisa Capuano, Placido Bramanti, Salvatore Cuzzocrea
Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease
Gunjan Dhawan, Colin K Combs
Inducible nitric oxide synthase is involved in the modulation of depressive behaviors induced by unpredictable chronic mild stress
Yun-Li Peng, Yu-Ning Liu, Lei Liu, Xia Wang, Chun-Lei Jiang, Yun-Xia Wang
Prevention of methamphetamine-induced microglial cell death by TNF-α and IL-6 through activation of the JAK-STAT pathway
Vanessa Coelho-Santos, Joana Gonçalves, Carlos Fontes-Ribeiro, Ana Paula Silva
NADPH oxidase-mediated redox signal contributes to lipoteichoic acid-induced MMP-9 upregulation in brain astrocytes
Hsi-Lung Hsieh, Chih-Chung Lin, Ruey-Horng Shih, Li-Der Hsiao, Chuen-Mao Yang
Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain
Bernhard T Baune, Carsten Konrad, Dominik Grotegerd, Thomas Suslow, Eva Birosova, Patricia Ohrmann, Jochen Bauer, Volker Arolt, Walter Heindel, Katharina Domschke, Sonja Schöning, Astrid V Rauch, Christina Uhlmann, Harald Kugel, Udo Dannlowski
Parkinson’s disease and immune system: is the culprit LRRKing in the periphery?
Elisa Greggio, Laura Civiero, Marco Bisaglia, Luigi Bubacco
Chemokine CCL2 and its receptor CCR2 in the medullary dorsal horn are involved in trigeminal neuropathic pain
Zhi-Jun Zhang, Yu-Lin Dong, Ying Lu, Su Cao, Zhi-Qi Zhao, Yong-Jing Gao
The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation
Fushan Shi, Lifeng Yang, Mohammed Kouadir, Yang Yang, Jihong Wang, Xiangmei Zhou, Xiaomin Yin, Deming Zhao
Corticotropin-releasing hormone and extracellular mitochondria augment IgE-stimulated human mast-cell vascular endothelial growth factor release, which is inhibited by luteolin
Shahrzad Asadi, Theoharis C Theoharides
Variability in detection and quantification of interferon β-1b–induced neutralizing antibodies
Hans-Peter Hartung, Bernd Kieseier, Douglas S Goodin, Barry GW Arnason, Giancarlo Comi, Stuart Cook, Massimo Filippi, Douglas R Jeffery, Ludwig Kappos, Timon Bogumil, Brigitte Stemper, Rupert Sandbrink, Yukiko Nakada, Haruhiko Nakajima, Susanne Schwenke, Stephan Lehr, Jürgen Heubach, Christoph Pohl, Joachim Reischl
Serum response factor modulates neuron survival during peripheral axon injury
Sina Stern, Daniela Sinske, Bernd Knöll
Elevated type I interferon-like activity in a subset of multiple sclerosis patients: molecular basis and clinical relevance
Alexander Hundeshagen, Michael Hecker, Brigitte Katrin Paap, Charlotte Angerstein, Ole Kandulski, Christian Fatum, Christiane Hartmann, Dirk Koczan, Hans-Juergen Thiesen, Uwe Klaus Zettl
Tumor necrosis factor-α synthesis inhibitor 3,6′-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer’s disease
David Tweedie, Ryan A Ferguson, Kelly Fishman, Kathryn A Frankola, Henriette Van Praag, Harold W Holloway, Weiming Luo, Yazhou Li, Luca Caracciolo, Isabella Russo, Sergio Barlati, Balmiki Ray, Debomoy K Lahiri, Francesca Bosetti, Nigel H Greig, Susanna Rosi
CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery
Moa Fransson, Elena Piras, Joachim Burman, Berith Nilsson, Magnus Essand, BinFeng Lu, Robert A Harris, Peetra U Magnusson, Eva Brittebo, Angelica SI Loskog
A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s disease
Branden Stansley, Jan Post, Kenneth Hensley
Early intervention with a small molecule inhibitor for tumor nefosis factor-α prevents cognitive deficits in a triple transgenic mouse model of Alzheimer’s disease
S Prasad Gabbita, Minu K Srivastava, Pirooz Eslami, Ming F Johnson, Naomi K Kobritz, David Tweedie, Nigel H Greig, Frank P Zemlan, Sherven P Sharma, Marni E Harris-White
(−)-Epigallocatechin gallate inhibits endotoxin-induced expression of inflammatory cytokines in human cerebral microvascular endothelial cells
Jieliang Li, Li Ye, Xu Wang, Jinping Liu, Yizhong Wang, Yu Zhou, Wenzhe Ho
Prenatal stress causes alterations in the morphology of microglia and the inflammatory response of the hippocampus of adult female mice
Yolanda Diz-Chaves, Olga Pernía, Paloma Carrero, Luis M Garcia-Segura
The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation
Niamh Murphy, Thelma R Cowley, Christoph W Blau, Colin N Dempsey, Janis Noonan, Aoife Gowran, Riffat Tanveer, Weredeselam M Olango, David P Finn, Veronica A Campbell, Marina A Lynch
Decreased MHC I expression in IFN gamma mutant mice alters synaptic elimination in the spinal cord after peripheral injury
Sheila CS Victório, Luciana P Cartarozzi, Rafaela CR Hell, Alexandre LR Oliveira
Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice
Qingshan Wang, Eun-Joo Shin, Xuan-Khanh Thi Nguyen, Quan Li, Jae-Hyung Bach, Guoying Bing, Won-Ki Kim, Hyoung-Chun Kim, Jau-Shyong Hong
Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A2-IIA in microvascular endothelial cells of the injured brain
Guansong Wang, Pin Qian, Zhi Xu, Jiqiang Zhang, Yaoli Wang, Saiyu Cheng, Wenqin Cai, Guisheng Qian, Changzheng Wang, Mark A DeCoster
Histamine modulates microglia function
Raquel Ferreira, Tiago Santos, Joana Gonçalves, Graça Baltazar, Lino Ferreira, Fabienne Agasse, Liliana Bernardino
IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma
Beatriz I Gallego, Juan J Salazar, Rosa de Hoz, Blanca Rojas, Ana I Ramírez, Manuel Salinas-Navarro, Arturo Ortín-Martínez, Francisco J Valiente-Soriano, Marcelino Avilés-Trigueros, Maria P Villegas-Perez, Manuel Vidal-Sanz, Alberto Triviño, Jose M Ramírez
Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation
Kai Fan, Xuefei Wu, Bin Fan, Ning Li, Yongzhong Lin, Yiwen Yao, Jianmei Ma
Telmisartan directly ameliorates the neuronal inflammatory response to IL-1β partly through the JNK/c-Jun and NADPH oxidase pathways
Tao Pang, Juan Wang, Julius Benicky, Enrique Sánchez-Lemus, Juan M Saavedra
The histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates human astrocyte neurotoxicity induced by interferon-γ
Sadayuki Hashioka, Andis Klegeris, Patrick L McGeer
Spontaneously hypertensive rats display reduced microglial activation in response to ischemic stroke and lipopolysaccharide
Deborah De Geyter, Wendy Stoop, Tine Zgavc, Sophie Sarre, Yvette Michotte, Jacques De Keyser, Ron Kooijman
Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury
Newton Cho, Dung H Nguyen, Kajana Satkunendrarajah, Donald R Branch, Michael G Fehlings
Lipopolysaccharide impairs amyloid beta efflux from brain: altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood–brain barrier
Michelle A Erickson, Pehr E Hartvigson, Yoichi Morofuji, Joshua B Owen, D Allan Butterfield, William A Banks
c-Src-dependent EGF receptor transactivation contributes to ET-1-induced COX-2 expression in brain microvascular endothelial cells
Hsi-Lung Hsieh, Chih-Chung Lin, Hui-Ju Chan, Caleb M Yang, Chuen-Mao Yang
Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases
Li Tian, Li Ma, Tiina Kaarela, Zhilin Li
Elevated serum levels of interleukin-17A in children with autism
Laila Yousef AL-Ayadhi, Gehan Ahmed Mostafa
Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion
Junfang Wu, Ahdeah Pajoohesh-Ganji, Bogdan A Stoica, Michael Dinizo, Kelsey Guanciale, Alan I Faden
C/EBPβ regulates multiple IL-1β-induced human astrocyte inflammatory genes
Jerel Fields, Anuja Ghorpade
Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory homeostatic nuclei
Kate Freeman, Anthony Brureau, Rajanikanth Vadigepalli, Mary M Staehle, Melanie M Brureau, Gregory E Gonye, Jan B Hoek, D Craig Hooper, James S Schwaber
Cytokines and olfactory bulb microglia in response to bacterial challenge in the compromised primary olfactory pathway
Rosalind P Herbert, Julie Harris, Kim Pei Chong, Jamie Chapman, Adrian K West, Meng Inn Chuah
Differential effects of interleukin-17 receptor signaling on innate and adaptive immunity during central nervous system bacterial infection
Debbie Vidlak, Tammy Kielian
Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathway
Vijay Ramesh, Deepti Nair, Shelley X L Zhang, Fahed Hakim, Navita Kaushal, Foaz Kayali, Yang Wang, Richard C Li, Alba Carreras, David Gozal
Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation
Jack van Horssen, Shailender Singh, Susanne van der Pol, Markus Kipp, Jamie L Lim, Laura Peferoen, Wouter Gerritsen, Evert-Jan Kooi, Maarten E Witte, Jeroen JG Geurts, Helga E de Vries, Regina Peferoen-Baert, Peter J van den Elsen, Paul van der Valk, Sandra Amor
Chronic ethanol increases systemic TLR3 agonist-induced neuroinflammation and neurodegeneration
Liya Qin, Fulton T Crews
Role of C-C chemokine receptor type 7 and its ligands during neuroinflammation
Shahani Noor, Emma H Wilson
Maternal immune activation by poly(I:C) induces expression of cytokines IL-1β and IL-13, chemokine MCP-1 and colony stimulating factor VEGF in fetal mouse brain
Géraldine Arrode-Brusés, Juan L Brusés
Viral-toxin interactions and Parkinson’s disease: poly(I:C) priming enhanced the neurodegenerative effects of paraquat
Jessica Bobyn, Emily N Mangano, Anusha Gandhi, Eric Nelson, Kerry Moloney, Melanie Clarke, Shawn Hayley
Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus
Donald J Alcendor, Ashley M Charest, Wen Qin Zhu, Hollie E Vigil, Susan M Knobel
Prokineticin 2 potentiates acid-sensing ion channel activity in rat dorsal root ganglion neurons
Chun-Yu Qiu, Yu-Qiang Liu, Fang Qiu, Jiliang Wu, Qun-Yong Zhou, Wang-Ping Hu
Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia
Maria Jose Pérez-Álvarez, Maria del Carmen Maza, Marta Anton, Lara Ordoñez, Francisco Wandosell
Inflammation modulates expression of laminin in the central nervous system following ischemic injury
Kyungmin Ji, Stella E Tsirka
Inhibition of CD200R1 expression by C/EBP beta in reactive microglial cells
Guido Dentesano, Marco Straccia, Aroa Ejarque-Ortiz, Josep M Tusell, Joan Serratosa, Josep Saura, Carme Solà
JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain
Lan-Wan Wang, Yi-Fang Tu, Chao-Ching Huang, Chien-Jung Ho
Neuroprotection by inhibiting the c-Jun N-terminal kinase pathway after cerebral ischemia occurs independently of interleukin-6 and keratinocyte-derived chemokine (KC/CXCL1) secretion
Corinne Benakis, Anne Vaslin, Christian Pasquali, Lorenz Hirt
Indomethacin protects rats from neuronal damage induced by traumatic brain injury and suppresses hippocampal IL-1β release through the inhibition of Nogo-A expression
Po-Kuan Chao, Kwok-Tung Lu, Ji-Yi Jhu, Yu-Yuan Peter Wo, Tai-Chun Huang, Long-Sun Ro, Yi-Ling Yang
Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling
Elaine L Pranski, Nirjari V Dalal, Jeremy H Herskowitz, Adam L Orr, Leah A Roesch, Jason J Fritz, Craig Heilman, James J Lah, Allan I Levey, Ranjita S Betarbet
A possible role for inflammation in mediating apoptosis of oligodendrocytes as induced by the Lyme disease spirochete Borrelia burgdorferi
Geeta Ramesh, Shemi Benge, Bapi Pahar, Mario T Philipp
α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation
Yuan Liu, Jun Hu, Jie Wu, Chenlei Zhu, Yujian Hui, Yaping Han, Zuhu Huang, Kevin Ellsworth, Weimin Fan
Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer’s disease
Lakshman Puli, Yuriy Pomeshchik, Katja Olas, Tarja Malm, Jari Koistinaho, Heikki Tanila
Erratum to: Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype
Konstantin Dirscherl, Marcus Karlstetter, Stefanie Ebert, Dominik Kraus, Julia Hlawatsch, Yana Walczak, Christoph Moehle, Rudolf Fuchshofer, Thomas Langmann
Immunodominant fragments of myelin basic protein initiate T cell-dependent pain
Huaqing Liu, Sergey A Shiryaev, Andrei V Chernov, Youngsoon Kim, Igor Shubayev, Albert G Remacle, Svetlana Baranovskaya, Vladislav S Golubkov, Alex Y Strongin, Veronica I Shubayev
Expression of Scavenger receptor A on antigen presenting cells is important for CD4+ T-cells proliferation in EAE mouse model
Hilit Levy-Barazany, Dan Frenkel
Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus
Ketan Chu, Bo Yin, Jingye Wang, Guoping Peng, Hui Liang, Ziqi Xu, Yue Du, Marong Fang, Qiang Xia, Benyan Luo
Immunoadsorption therapy in patients with multiple sclerosis with steroid-refractory optical neuritis
Michael J Koziolek, Desiree Tampe, Matthias Bähr, Hassan Dihazi, Klaus Jung, Dirk Fitzner, Reinhard Klingel, Gerhard A Müller, Bernd Kitze
CXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation
Markus C Kowarik, Sabine Cepok, Johann Sellner, Verena Grummel, Martin S Weber, Thomas Korn, Achim Berthele, Bernhard Hemmer
MicroRNA-124 as a novel treatment for persistent hyperalgesia
Hanneke LDM Willemen, Xiao-Jiao Huo, Qi-Liang Mao-Ying, Jitske Zijlstra, Cobi J Heijnen, Annemieke Kavelaars
Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population
Nan Zhao, Xin Liu, Yongqin Wang, Xiaoqiu Liu, Jiana Li, Litian Yu, Liyuan Ma, Shuyu Wang, Hongye Zhang, Lisheng Liu, Jingbo Zhao, Xingyu Wang
Spatial and temporal correlation in progressive degeneration of neurons and astrocytes in contusion-induced spinal cord injury
Kyoung-Jin Min, Hey-Kyeong Jeong, Beomsue Kim, Dong Hoon Hwang, Hae Young Shin, An Tran Nguyen, Jong-hyeon Kim, Ilo Jou, Byung G Kim, Eun-hye Joe
IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils
Carine Savarin, Stephen A Stohlman, David R Hinton, Richard M Ransohoff, Daniel J Cua, Cornelia C Bergmann
LPS-induced release of IL-6 from glia modulates production of IL-1β in a JAK2-dependent manner
Aedín M Minogue, James P Barrett, Marina A Lynch
HIV-1 Tat C-mediated regulation of tumor necrosis factor receptor-associated factor-3 by microRNA 32 in human microglia
Ritu Mishra, Chintan Chhatbar, Sunit Kumar Singh
Complement activation in the injured central nervous system: another dual-edged sword?
Faith H Brennan, Aileen J Anderson, Stephen M Taylor, Trent M Woodruff, Marc J Ruitenberg
Treatment with MOG-DNA vaccines induces CD4+CD25+FoxP3+ regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitis
Nicolás Fissolo, Carme Costa, Ramil N Nurtdinov, Marta F Bustamante, Victor Llombart, María J Mansilla, Carmen Espejo, Xavier Montalban, Manuel Comabella
Transient early neurotrophin release and delayed inflammatory cytokine release by microglia in response to PAR-2 stimulation
Chen-wen Chen, Qian-bo Chen, Qing Ouyang, Ji-hu Sun, Fang-ting Liu, Dian-wen Song, Hong-bin Yuan
Transforming growth factor β1-induced astrocyte migration is mediated in part by activating 5-lipoxygenase and cysteinyl leukotriene receptor 1
Xue-Qin Huang, Xia-Yan Zhang, Xiao-Rong Wang, Shu-Ying Yu, San-Hua Fang, Yun-Bi Lu, Wei-Ping Zhang, Er-Qing Wei
Efficient isolation of live microglia with preserved phenotypes from adult mouse brain
Maria Nikodemova, Jyoti J Watters
The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity
Endong Li, Mariko Noda, Yukiko Doi, Bijay Parajuli, Jun Kawanokuchi, Yoshifumi Sonobe, Hideyuki Takeuchi, Tetsuya Mizuno, Akio Suzumura
Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity
Hyejin Jeon, Jong-Heon Kim, Jae-Hong Kim, Won-Ha Lee, Myung-Shik Lee, Kyoungho Suk
Effects of dimethyl fumarate on neuroprotection and immunomodulation
Philipp Albrecht, Imane Bouchachia, Norbert Goebels, Nadine Henke, Harald H Hofstetter, Andrea Issberner, Zsuzsa Kovacs, Jan Lewerenz, Dmitrij Lisak, Pamela Maher, Anne-Kathrin Mausberg, Kim Quasthoff, Corinna Zimmermann, Hans-Peter Hartung, Axel Methner
Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin
Smadar Hadas, Maya Spira, Uwe-Karsten Hanisch, Fanny Reichert, Shlomo Rotshenker
Downstream Toll-like receptor signaling mediates adaptor-specific cytokine expression following focal cerebral ischemia
Famakin Bolanle, Mou Yongshan, Spatz Maria, Lawal Modinat, John Hallenbeck
Acute injury in the peripheral nervous system triggers an alternative macrophage response
Elke Ydens, Anje Cauwels, Bob Asselbergh, Sofie Goethals, Lieve Peeraer, Guillaume Lornet, Leonardo Almeida-Souza, Jo A Van Ginderachter, Vincent Timmerman, Sophie Janssens
Inhibition of EGFR/MAPK signaling reduces microglial inflammatory response and the associated secondary damage in rats after spinal cord injury
Wen-sheng Qu, Dai-shi Tian, Zhi-bao Guo, Jun Fang, Qiang Zhang, Zhi-yuan Yu, Min-jie Xie, Hua-qiu Zhang, Jia-gao Lü, Wei Wang
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
David H Cribbs, Nicole C Berchtold, Victoria Perreau, Paul D Coleman, Joseph Rogers, Andrea J Tenner, Carl W Cotman
Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system
Astrid Bottelbergs, Simon Verheijden, Paul P Van Veldhoven, Wilhelm Just, Rita Devos, Myriam Baes
Albumin induces upregulation of matrix metalloproteinase-9 in astrocytes via MAPK and reactive oxygen species-dependent pathways
Hantamalala Ralay Ranaivo, Jessica N Hodge, Nicole Choi, Mark S Wainwright
Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation
Richard Gordon, Vellareddy Anantharam, Anumantha G Kanthasamy, Arthi Kanthasamy
Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures
Hiromi Kumamaru, Hirokazu Saiwai, Kazu Kobayakawa, Kensuke Kubota, Nico van Rooijen, Kazuhide Inoue, Yukihide Iwamoto, Seiji Okada
Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit
Jérôme Badaut, Jean-Christophe Copin, Andrew M Fukuda, Yvan Gasche, Karl Schaller, Rafaela F da Silva
Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors?
Jürg Gertsch, Sharon Anavi-Goffer
Cytotoxic CD8+ T cells and CD138+ plasma cells prevail in cerebrospinal fluid in non-paraneoplastic cerebellar ataxia with contactin-associated protein-2 antibodies
Nico Melzer, Kristin S Golombeck, Catharina C Gross, Sven G Meuth, Heinz Wiendl
Pre-infection physical exercise decreases mortality and stimulates neurogenesis in bacterial meningitis
David Liebetanz, Joachim Gerber, Christina Schiffner, Sandra Schütze, Florian Klinker, Hubertus Jarry, Roland Nau, Simone C Tauber
Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury
Bobbi Fleiss, Marie KL Nilsson, Klas Blomgren, Carina Mallard
P2X7 signaling promotes microsphere embolism-triggered microglia activation by maintaining elevation of Fas ligand
Ying-mei Lu, Rong-rong Tao, Ji-yun Huang, Li-tao Li, Mei-hua Liao, Xiao-ming Li, Kohji Fukunaga, Ze-Hui Hong, Feng Han
CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species
Yee Andy Yeo, Julia M Martínez Gómez, J Ludovic Croxford, Stephan Gasser, Eng-Ang Ling, Herbert Schwarz
A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: relevance to multiple sclerosis
Smriti M Agrawal, Claudia Silva, Janet Wang, Jade Pui-Wai Tong, V Wee Yong
Identification of potential biomarkers of gold nanoparticle toxicity in rat brains
Nikhat J Siddiqi, Mohamed Anwar K Abdelhalim, Afaf K El-Ansary, Abdullah S Alhomida, W Y Ong
IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments
Nina Vardjan, Mateja Gabrijel, Maja Potokar, Urban Švajger, Marko Kreft, Matjaž Jeras, Yolanda de Pablo, Maryam Faiz, Milos Pekny, Robert Zorec
Intravenous immunoglobulin treatment of the post-polio syndrome: sustained effects on quality of life variables and cytokine expression after one year follow up
Henrik Gonzalez, Mohsen Khademi, Kristian Borg, Tomas Olsson
Podosomes in migrating microglia: components and matrix degradation
Catherine Vincent, Tamjeed A Siddiqui, Lyanne C Schlichter
Relationship between plasma high mobility group box-1 protein levels and clinical outcomes of aneurysmal subarachnoid hemorrhage
Xiang-Dong Zhu, Jing-Sen Chen, Feng Zhou, Qi-Chang Liu, Gao Chen, Jian-Min Zhang
Etiology of autistic features: the persisting neurotoxic effects of propionic acid
Afaf K El-Ansary, Abir Ben Bacha, Malak Kotb
Involvement of 5-lipoxygenase activating protein in the amyloidotic phenotype of an Alzheimer’s disease mouse model
Jin Chu, Domenico Praticò
Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier
Ruben van Doorn, Melissa A Lopes Pinheiro, Gijs Kooij, Kim Lakeman, Bert van het Hof, Susanne MA van der Pol, Dirk Geerts, Jack van Horssen, Paul van der Valk, Elizabeth van der Kam, Eric Ronken, Arie Reijerkerk, Helga E de Vries
Neuronal apoptosis by HIV-1 Vpr: contribution of proinflammatory molecular networks from infected target cells
Debjani Guha, Pruthvi Nagilla, Carrie Redinger, Alagarsamy Srinivasan, Gerald P Schatten, Velpandi Ayyavoo
Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats
Stanka Mihaylova, Anke Killian, Konstantin Mayer, Soni Savai Pullamsetti, Ralph Schermuly, Bernhard Rosengarten
Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation
Fahim Ebrahimi, Marco Koch, Philipp Pieroh, Chalid Ghadban, Constance Hobusch, Ingo Bechmann, Faramarz Dehghani
Multiplex array proteomics detects increased MMP-8 in CSF after spinal cord injury
Matthew Light, Kenneth H Minor, Peter DeWitt, Kyle H Jasper, Stephen JA Davies
Long-term impact of systemic bacterial infection on the cerebral vasculature and microglia
Ursula Püntener, Steven G Booth, V Hugh Perry, Jessica L Teeling
Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway
Ana Patrícia Simões, João A Duarte, Fabienne Agasse, Paula Margarida Canas, Angelo R Tomé, Paula Agostinho, Rodrigo A Cunha
Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson’s disease
Valerio Pisani, Alessandro Stefani, Mariangela Pierantozzi, Silvia Natoli, Paolo Stanzione, Diego Franciotta, Antonio Pisani
A single intraperitoneal injection of endotoxin in rats induces long-lasting modifications in behavior and brain protein levels of TNF-α and IL-18
Paola Bossù, Debora Cutuli, Ilaria Palladino, Paola Caporali, Francesco Angelucci, Daniela Laricchiuta, Francesca Gelfo, Paola De Bartolo, Carlo Caltagirone, Laura Petrosini
Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus
Yao-Chung Chuang, Tsu-Kung Lin, Hsuan-Ying Huang, Wen-Neng Chang, Chia-Wei Liou, Shang-Der Chen, Alice YW Chang, Samuel HH Chan
Anti-inflammatory/anti-amyloidogenic effects of plasmalogens in lipopolysaccharide-induced neuroinflammation in adult mice
Masataka Ifuku, Toshihiko Katafuchi, Shiro Mawatari, Mami Noda, Kiyotaka Miake, Masaaki Sugiyama, Takehiko Fujino
Preventive immunization of aged and juvenile non-human primates to beta-amyloid
Julia Kofler, Brian Lopresti, Chris Janssen, Anita M Trichel, Eliezer Masliah, Olivera J Finn, Russell D Salter, Geoffrey H Murdoch, Chester A Mathis, Clayton A Wiley
Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation
Carina Halleskog, Jacomijn Petronella Dijksterhuis, Michaela Brita Christina Kilander, Javier Becerril-Ortega, Juan Carlos Villaescusa, Eva Lindgren, Ernest Arenas, Gunnar Schulte
Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain
Tzuping Wei, Tian-Zhi Guo, Wen-Wu Li, Saiyun Hou, Wade S Kingery, John David Clark
Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats
Seok Joon Won, Byung Hoon Yoo, Tiina M Kauppinen, Bo Young Choi, Jin Hee Kim, Bong Geom Jang, Min Woo Lee, Min Sohn, Jialing Liu, Raymond A Swanson, Sang Won Suh
The immunology of traumatic brain injury: a prime target for Alzheimer’s disease prevention
Brian Giunta, Demian Obregon, Renuka Velisetty, Paul R Sanberg, Cesar V Borlongan, Jun Tan
Conditional expression of human β-hexosaminidase in the neurons of Sandhoff disease rescues mice from neurodegeneration but not neuroinflammation
Stephanos Kyrkanides, Sabine M Brouxhon, Ross H Tallents, Jen-nie H Miller, John A Olschowka, M Kerry O’Banion
Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain
Charlotte Schmitt, Nathalie Strazielle, Jean-François Ghersi-Egea
CC chemokine ligand 2 upregulates the current density and expression of TRPV1 channels and Nav1.8 sodium channels in dorsal root ganglion neurons
Der-Jang Kao, Allen H Li, Jin-Chung Chen, Ro-Sun Luo, Ying-Ling Chen, Juu-Chin Lu, Hung-Li Wang
Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury
Ivan Bohacek, Pierre Cordeau, Mélanie Lalancette–Hébert, Dunja Gorup, Yuan-Cheng Weng, Srecko Gajovic, Jasna Kriz
Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis
Jeffrey H Mills, Leah M Alabanza, Deeqa A Mahamed, Margaret S Bynoe
Adenosine A2B receptor-mediated leukemia inhibitory factor release from astrocytes protects cortical neurons against excitotoxicity
Shamsudheen Moidunny, Jonathan Vinet, Evelyn Wesseling, Johan Bijzet, Chu-Hsin Shieh, Sven CD van Ijzendoorn, Paola Bezzi, Hendrikus WGM Boddeke, Knut Biber
Pro-inflammatory interleukin-18 increases Alzheimer’s disease-associated amyloid-β production in human neuron-like cells
Elina M Sutinen, Tuula Pirttilä, George Anderson, Antero Salminen, Johanna O Ojala
Reduced serum concentrations of 25-hydroxy vitamin D in children with autism: Relation to autoimmunity
Gehan A Mostafa, Laila Y AL-Ayadhi
Hydrogen sulfide attenuates spatial memory impairment and hippocampal neuroinflammation in beta-amyloid rat model of Alzheimer’s disease
Aiguo Xuan, Dahong Long, Jianhua Li, Weidong Ji, Meng Zhang, Lepeng Hong, Jihong Liu
Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophrenia
Ilaria Palladino, Francesca Salani, Antonio Ciaramella, Ivo Alex Rubino, Carlo Caltagirone, Sabrina Fagioli, Gianfranco Spalletta, Paola Bossù
IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis
Mahdia Benkhoucha, Nicolas Molnarfi, Marie-Laure Santiago-Raber, Martin S Weber, Doron Merkler, Mattias Collin, Patrice H Lalive
Activation of kinin B1 receptor evokes hyperthermia through a vagal sensory mechanism in the rat
Sébastien Talbot, Helaine De Brito Gariépy, Julien Saint-Denis, Réjean Couture
Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus
Cristina Pintado, María P Gavilán, Elena Gavilán, Luisa García-Cuervo, Antonia Gutiérrez, Javier Vitorica, Angélica Castaño, Rosa M Ríos, Diego Ruano
Neuroinflammation and oxidative stress in rostral ventrolateral medulla contribute to neurogenic hypertension induced by systemic inflammation
Kay LH Wu, Samuel HH Chan, Julie YH Chan
IL-1 signal affects both protection and pathogenesis of virus-induced chronic CNS demyelinating disease
Byung S Kim, Young-Hee Jin, Liping Meng, Wanqiu Hou, Hyun Seok Kang, Hey Suk Park, Chang-Sung Koh
Time-dependent effects of hypothermia on microglial activation and migration
Jung-Wan Seo, Jong-Heon Kim, Jae-Hong Kim, Minchul Seo, Hyung Soo Han, Jaechan Park, Kyoungho Suk
The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders
Raymond H Thomas, Melissa M Meeking, Jennifer R Mepham, Lisa Tichenoff, Fred Possmayer, Suya Liu, Derrick F MacFabe
The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis
Shujun Ge, Bandana Shrestha, Debayon Paul, Carolyn Keating, Robert Cone, Angelo Guglielmotti, Joel S Pachter
Primary phagocytosis of viable neurons by microglia activated with LPS or Aβ is dependent on calreticulin/LRP phagocytic signalling
Michael Fricker, María José Oliva-Martín, Guy C Brown
Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro
Sophie Leow-Dyke, Charlotte Allen, Adam Denes, Olov Nilsson, Samaneh Maysami, Andrew G Bowie, Nancy J Rothwell, Emmanuel Pinteaux
Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice
Dimitrije Krstic, Amrita Madhusudan, Jana Doehner, Prisca Vogel, Tina Notter, Claudine Imhof, Abigail Manalastas, Martina Hilfiker, Sandra Pfister, Cornelia Schwerdel, Carsten Riether, Urs Meyer, Irene Knuesel
IL-1β reactivity and the development of severe fatigue after military deployment: a longitudinal study
Mirjam van Zuiden, Annemieke Kavelaars, Karima Amarouchi, Mirjam Maas, Eric Vermetten, Elbert Geuze, Cobi J Heijnen
Secreted phospholipase A2-IIA-induced a phenotype of activated microglia in BV-2 cells requires epidermal growth factor receptor transactivation and proHB-EGF shedding
Rubén Martín, Claudia Cordova, Maria L Nieto
The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain
Polina Feldman, Michael R Due, Matthew S Ripsch, Rajesh Khanna, Fletcher A White
Astrocyte elevated gene-1 regulates astrocyte responses to neural injury: implications for reactive astrogliosis and neurodegeneration
Neha Vartak-Sharma, Anuja Ghorpade
Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse
Peter J Gaskill, Loreto Carvallo, Eliseo A Eugenin, Joan W Berman
Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways
Sarah D Schlatterer, Hyeon-sook Suh, Concepcion Conejero-Goldberg, Shufen Chen, Christopher M Acker, Sunhee C Lee, Peter Davies
TGFβ signalling plays an important role in IL4-induced alternative activation of microglia
Xiaolai Zhou, Björn Spittau, Kerstin Krieglstein
Low-level laser therapy regulates microglial function through Src-mediated signaling pathways: implications for neurodegenerative diseases
Sheng Song, Feifan Zhou, Wei R Chen
Macrophage imbalance (M1 vs. M2) and upregulation of mast cells in wall of ruptured human cerebral aneurysms: preliminary results
David Hasan, Nohra Chalouhi, Pascal Jabbour, Tomoki Hashimoto
Toll-like receptors 4 and 9 are responsible for the maintenance of the inflammatory reaction in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis
Arianna Maiolini, Regina Carlson, Andrea Tipold
Expression of myeloid differentiation factor 88 in neurons is not requisite for the induction of sickness behavior by interleukin-1β
Theodore P Braun, Aaron J Grossberg, Biliana O Veleva-Rotse, Julia E Maxson, Marek Szumowski, Anthony P Barnes, Daniel L Marks
Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson’s disease
Anamitra Ghosh, Arthi Kanthasamy, Joy Joseph, Vellareddy Anantharam, Pallavi Srivastava, Brian P Dranka, Balaraman Kalyanaraman, Anumantha G Kanthasamy
Protein expression profiling of inflammatory mediators in human temporal lobe epilepsy reveals co-activation of multiple chemokines and cytokines
Anne A Kan, Wilco de Jager, Marina de Wit, Cobi Heijnen, Mirjam van Zuiden, Cyrill Ferrier, Peter van Rijen, Peter Gosselaar, Ellen Hessel, Onno van Nieuwenhuizen, Pierre N E de Graan
Preserved vascular integrity and enhanced survival following neuropilin-1 inhibition in a mouse model of CD8 T cell-initiated CNS vascular permeability
Georgette L Suidan, Jonathan W Dickerson, Holly L Johnson, Theresa W Chan, Kevin D Pavelko, Istvan Pirko, Kim B Seroogy, Aaron J Johnson
Pharmacokinetics and modeling of immune cell trafficking: quantifying differential influences of target tissues versus lymphocytes in SJL and lipopolysaccharide-treated mice
William A Banks, Michael L Niehoff, Nicholas M Ponzio, Michelle A Erickson, Steven S Zalcman
Apolipoprotein C-I is an APOE genotype-dependent suppressor of glial activation
Eiron Cudaback, Xianwu Li, Yue Yang, Thomas Yoo, Kathleen S Montine, Suzanne Craft, Thomas J Montine, Christopher Dirk Keene
The microRNA miR-181c controls microglia-mediated neuronal apoptosis by suppressing tumor necrosis factor
Li Zhang, Lian-Yan Dong, Ya-Jian Li, Zhen Hong, Wen-Shi Wei
Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis
Roberta Brambilla, Galina Dvoriantchikova, David Barakat, Dmitry Ivanov, John R Bethea, Valery I Shestopalov
Immunoglobulin G (IgG) attenuates neuroinflammation and improves neurobehavioral recovery after cervical spinal cord injury
Dung Hoang Nguyen, Newton Cho, Kajana Satkunendrarajah, James W Austin, Jian Wang, Michael G Fehlings
Cellular sources of dysregulated cytokines in relapsing-remitting multiple sclerosis
Jeppe Romme Christensen, Lars Börnsen, Dan Hesse, Martin Krakauer, Per Soelberg Sørensen, Helle Bach Søndergaard, Finn Sellebjerg
Dok2 mediates the CD200Fc attenuation of Aβ-induced changes in glia
Anthony Lyons, Eric J Downer, Derek A Costello, Niamh Murphy, Marina A Lynch
Complement is dispensable for neurodegeneration in Niemann-Pick disease type C
Manuel E Lopez, Andres D Klein, Matthew P Scott
Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice
Markus Britschgi, Yoshiko Takeda-Uchimura, Edward Rockenstein, Hudson Johns, Eliezer Masliah, Tony Wyss-Coray
Prevention of hypoglycemia-induced neuronal death by minocycline
Seok Joon Won, Jin Hee Kim, Byung Hoon Yoo, Min Sohn, Tiina M Kauppinen, Man-Seong Park, Hyung-Joo Kwon, Jialing Liu, Sang Won Suh
670-nm light treatment reduces complement propagation following retinal degeneration
Matt Rutar, Riccardo Natoli, Rizalyn Albarracin, Krisztina Valter, Jan Provis
Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling
Michael R Due, Andrew D Piekarz, Natalie Wilson, Polina Feldman, Matthew S Ripsch, Sherry Chavez, Hang Yin, Rajesh Khanna, Fletcher A White
Impact of intravenous immunoglobulin on the dopaminergic system and immune response in the acute MPTP mouse model of Parkinson’s disease
Isabelle St-Amour, Mélanie Bousquet, Isabelle Paré, Janelle Drouin-Ouellet, Francesca Cicchetti, Renée Bazin, Frédéric Calon
Vitamin D mitigates age-related cognitive decline through the modulation of pro-inflammatory state and decrease in amyloid burden
Teresita L Briones, Hala Darwish
TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis
Richard J Mellanby, Helen Cambrook, Darryl G Turner, Richard A O’Connor, Melanie D Leech, Florian C Kurschus, Andrew S MacDonald, Bernd Arnold, Stephen M Anderton
Acetate supplementation reduces microglia activation and brain interleukin-1β levels in a rat model of Lyme neuroborreliosis
Catherine A Brissette, Heidi M Houdek, Angela M Floden, Thad A Rosenberger
Polymorphism of tumor necrosis factor alpha (TNF-alpha) gene promoter, circulating TNF-alpha level, and cardiovascular risk factor for ischemic stroke
Guanglin Cui, Haoran Wang, Rui Li, Lina Zhang, Zongzhe Li, Yan Wang, Rutai Hui, Hu Ding, Dao Wen Wang
Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury
Jenna M Ziebell, Samuel E Taylor, Tuoxin Cao, Jordan L Harrison, Jonathan Lifshitz
Cerebrospinal fluid and plasma cytokines after subarachnoid haemorrhage: CSF interleukin-6 may be an early marker of infection
Stephen J Hopkins, Catherine J McMahon, Navneet Singh, James Galea, Margaret Hoadley, Sylvia Scarth, Hiren Patel, Andy Vail, Sharon Hulme, Nancy J Rothwell, Andrew T King, Pippa J Tyrrell
Transcriptome analysis of the ependymal barrier during murine neurocysticercosis
Pramod Kumar Mishra, Judy M Teale
SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S-nitrosylation of protein disulfide isomerase (PDI)
Xueping Chen, Teng Guan, Chen Li, Huifang Shang, Liying Cui, Xin-Min Li, Jiming Kong
Carriers of the fragile X mental retardation 1 (FMR1) premutation allele present with increased levels of cytokine IL-10
Diana Marek, Stephanie Papin, Kim Ellefsen, Julien Niederhauser, Nathalie Isidor, Adriana Ransijn, Lucienne Poupon, Francois Spertini, Giuseppe Pantaleo, Sven Bergmann, Jacques S Beckmann, Sebastien Jacquemont, Goranka Tanackovic
Rescue from acute neuroinflammation by pharmacological chemokine-mediated deviation of leukocytes
Nele Berghmans, Hubertine Heremans, Sandra Li, Erik Martens, Patrick Matthys, Lydia Sorokin, Jo Van Damme, Ghislain Opdenakker
Interleukin-1 beta-induced up-regulation of opioid receptors in the untreated and morphine-desensitized U87 MG human astrocytoma cells
Linda Staikos Byrne, Jinsong Peng, Sraboni Sarkar, Sulie L Chang
Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5
Jharon Silva, Oksana Polesskaya, Walter Knight, Johnny Ting Zheng, Megan Granger, Tenée Lopez, Fernando Ontiveros, Changyong Feng, Chen Yan, Karl A Kasischke, Stephen Dewhurst
Transcriptomics and proteomics analyses of the PACAP38 influenced ischemic brain in permanent middle cerebral artery occlusion model mice
Motohide Hori, Tomoya Nakamachi, Randeep Rakwal, Junko Shibato, Tetsuo Ogawa, Toshihiro Aiuchi, Tatsuaki Tsuruyama, Keiji Tamaki, Seiji Shioda
The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia
Shuwen Cao, David G Standaert, Ashley S Harms
Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation
Crystal Bethel-Brown, Honghong Yao, Guoku Hu, Shilpa Buch
New perspectives on central and peripheral immune responses to acute traumatic brain injury
Mahasweta Das, Subhra Mohapatra, Shyam S Mohapatra
Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells
Boonrat Chantong, Denise V Kratschmar, Lyubomir G Nashev, Zoltan Balazs, Alex Odermatt
Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages
Daniel R Getts, Rachael L Terry, Meghann Teague Getts, Marcus Müller, Sabita Rana, Celine Deffrasnes, Thomas Myles Ashhurst, Jane Radford, Markus Hofer, Shane Thomas, Iain L Campbell, Nicholas JC King
Programming of neurotoxic cofactor CXCL-10 in HIV-1-associated dementia: abrogation of CXCL-10-induced neuro-glial toxicity in vitro by PKC activator
Rajeev Mehla, Shalmali Bivalkar-Mehla, Mitzi Nagarkatti, Ashok Chauhan
Opposing effects of Toll-like receptors 2 and 4 on synaptic stability in the spinal cord after peripheral nerve injury
Camila Marques Freria, Licio Augusto Velloso, Alexandre LR Oliveira
Dendritic cell CNS recruitment correlates with disease severity in EAE via CCL2 chemotaxis at the blood–brain barrier through paracellular transmigration and ERK activation
Divya Sagar, Anne Lamontagne, Catherine A Foss, Zafar K Khan, Martin G Pomper, Pooja Jain
Association of dimethylarginines and mediators of inflammation after acute ischemic stroke
Shufen Chen, Jens Martens-Lobenhoffer, Karin Weissenborn, Jan T Kielstein, Ralf Lichtinghagen, Milani Deb-Chatterji, Na Li, Anita B Tryc, Annemarie Goldbecker, Qiang Dong, Stefanie M Bode-Böger, Hans Worthmann
PINK1 positively regulates IL-1β-mediated signaling through Tollip and IRAK1 modulation
Hyun Jung Lee, Kwang Chul Chung
Metabotropic glutamate receptor 5 contributes to inflammatory tongue pain via extracellular signal-regulated kinase signaling in the trigeminal spinal subnucleus caudalis and upper cervical spinal cord
Ming-Gang Liu, Shingo Matsuura, Masamichi Shinoda, Kuniya Honda, Ikuko Suzuki, Kazuo Shibuta, Takaaki Tamagawa, Ayano Katagiri, Masaaki Kiyomoto, Kinuyo Ohara, Akihiko Furukawa, Kentaro Urata, Koichi Iwata
RETRACTED ARTICLE: Alteration of astrocytes and Wnt/β-catenin signaling in the frontal cortex of autistic subjects
Fujiang Cao, Ailan Yin, Guang Wen, Ashfaq M Sheikh, Zujaja Tauqeer, Mazhar Malik, Amenah Nagori, Michael Schirripa, Frank Schirripa, George Merz, W Ted Brown, Xiaohong Li
LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein
Daniel F Marker, Jenna M Puccini, Taryn E Mockus, Justin Barbieri, Shao-Ming Lu, Harris A Gelbard
Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment
Liying Zhuang, Xiaoyan Liu, Xiaohui Xu, Chunxian Yue, Hao Shu, Feng Bai, Hui Yu, Yongmei Shi, Zhijun Zhang
Endotoxin- and ATP-neutralizing activity of alkaline phosphatase as a strategy to limit neuroinflammation
Ruth Huizinga, Karim L Kreft, Sabina Onderwater, Joke G Boonstra, Ruud Brands, Rogier Q Hintzen, Jon D Laman
Sevoflurane reduces clinical disease in a mouse model of multiple sclerosis
Paul E Polak, Randall O Dull, Sergey Kalinin, Anthony J Sharp, Richard Ripper, Guy Weinberg, David E Schwartz, Israel Rubinstein, Douglas L Feinstein
Regulation of Kir4.1 expression in astrocytes and astrocytic tumors: a role for interleukin-1 β
Emanuele Zurolo, Marjolein de Groot, Anand Iyer, Jasper Anink, Erwin A van Vliet, Jan J Heimans, Jaap C Reijneveld, Jan A Gorter, Eleonora Aronica
Changes in serum and cerebrospinal fluid cytokines in response to non-neurological surgery: an observational study
Sara Bromander, Rolf Anckarsäter, Marianne Kristiansson, Kaj Blennow, Henrik Zetterberg, Henrik Anckarsäter, Caroline E Wass
The chemokine, macrophage inflammatory protein-2γ, reduces the expression of glutamate transporter-1 on astrocytes and increases neuronal sensitivity to glutamate excitotoxicity
Jie Fang, Deping Han, Jinsheng Hong, Qi Tan, Yeping Tian
Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis
Timothy W Phares, Stephen A Stohlman, David R Hinton, Cornelia C Bergmann
Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration
Matt Rutar, Riccardo Natoli, Jan M Provis
Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia
Makoto Horiuchi, Kouji Wakayama, Aki Itoh, Kumi Kawai, David Pleasure, Keiko Ozato, Takayuki Itoh
Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population
Peter A Walker, Supinder S Bedi, Shinil K Shah, Fernando Jimenez, Hasen Xue, Jason A Hamilton, Philippa Smith, Chelsea P Thomas, Robert W Mays, Shibani Pati, Charles S Cox Jr
Evaluation of age-related changes in translocator protein (TSPO) in human brain using 11C-[R]-PK11195 PET
Ajay Kumar, Otto Muzik, Varun Shandal, Diane Chugani, Pulak Chakraborty, Harry T Chugani
Susceptibility of juvenile and adult blood–brain barrier to endothelin-1: regulation of P-glycoprotein and breast cancer resistance protein expression and transport activity
Rania Harati, Anne-Sophie Villégier, William A Banks, Aloise Mabondzo
GLP-1 secretion by microglial cells and decreased CNS expression in obesity
Camilla Kappe, Linda M Tracy, Cesare Patrone, Kerstin Iverfeldt, Åke Sjöholm
Regulation of podosome formation, microglial migration and invasion by Ca2+-signaling molecules expressed in podosomes
Tamjeed A Siddiqui, Starlee Lively, Catherine Vincent, Lyanne C Schlichter
Aquaporin 4: a player in cerebral edema and neuroinflammation
Andrew M Fukuda, Jerome Badaut
Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes
Miklós Sárvári, Erik Hrabovszky, Imre Kalló, Norbert Solymosi, István Likó, Nicole Berchtold, Carl Cotman, Zsolt Liposits
The antiprotozoal drug pentamidine ameliorates experimentally induced acute colitis in mice
Giuseppe Esposito, Elena Capoccia, Giovanni Sarnelli, Caterina Scuderi, Carla Cirillo, Rosario Cuomo, Luca Steardo
Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines
Shan Hu, Qi-Liang Mao-Ying, Jun Wang, Zhi-Fu Wang, Wen-Li Mi, Xiao-Wei Wang, Jian-Wei Jiang, Ya-Lin Huang, Gen-Cheng Wu, Yan-Qing Wang
Inflammatory monocytes and the pathogenesis of viral encephalitis
Rachael L Terry, Daniel R Getts, Celine Deffrasnes, Caryn van Vreden, Iain L Campbell, Nicholas JC King
Regulation of enhanced cerebrovascular expression of proinflammatory mediators in experimental subarachnoid hemorrhage via the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway
Aida Maddahi, Gro Povlsen, Lars Edvinsson
L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the ‘collusion’ hypothesis for increased extracellular L-glutamate concentration in neuroinflammation
Junpei Takaki, Koki Fujimori, Marie Miura, Takeshi Suzuki, Yuko Sekino, Kaoru Sato
Pain in experimental autoimmune encephalitis: a comparative study between different mouse models
Jianning Lu, Martina Kurejova, Laura N Wirotanseng, Ralf A Linker, Rohini Kuner, Anke Tappe-Theodor
Upregulation of mesencephalic astrocyte-derived neurotrophic factor in glial cells is associated with ischemia-induced glial activation
Yujun Shen, Aimin Sun, Yunhong Wang, Daqin Cha, Haiping Wang, Facai Wang, Lijie Feng, Shengyun Fang, Yuxian Shen
GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia
Bijay Parajuli, Yoshifumi Sonobe, Jun Kawanokuchi, Yukiko Doi, Mariko Noda, Hideyuki Takeuchi, Tetsuya Mizuno, Akio Suzumura