Ausgabe 1/2008
Inhalt (81 Artikel)
Elevated expressions of survivin and VEGF protein are strong independent predictors of survival in advanced nasopharyngeal carcinoma
Yu-Hong Li, Chun-Fang Hu, Qiong Shao, Ma-Yan Huang, Jing-Hui Hou, Dan Xie, Yi-Xin Zeng, Jian-Yong Shao
Should tumor VEGF expression influence decisions on combining low-dose chemotherapy with antiangiogenic therapy? Preclinical modeling in ovarian cancer
David O Holtz, Robert T Krafty, Alisha Mohamed-Hadley, Lin Zhang, Ioannis Alagkiozidis, Benjamin Leiby, Wensheng Guo, Phyllis A Gimotty, George Coukos
A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient
Mark JS Miller, Brian K Reuter, John L Wallace, Keith A Sharkey
Quantitative image analysis of intra-tumoral bFGF level as a molecular marker of paclitaxel resistance
Colin T Walsh, Yong Wei, M Guillaume Wientjes, Jessie LS Au
Ex Vivo Metrics™, a preclinical tool in new drug development
C Gerald Curtis, Kevin Bilyard, Hugo Stephenson
A phase I clinical study of vaccination of melanoma patients with dendritic cells loaded with allogeneic apoptotic/necrotic melanoma cells. Analysis of toxicity and immune response to the vaccine and of IL-10 -1082 promoter genotype as predictor of disease progression
Erika M von Euw, María M Barrio, David Furman, Estrella M Levy, Michele Bianchini, Isabelle Peguillet, Olivier Lantz, Alejandra Vellice, Abraham Kohan, Matías Chacón, Cassian Yee, Rosa Wainstok, José Mordoh
Human embryonic stem cells: preclinical perspectives
Kaushik Dilip Deb, Kanchan Sarda
The Italian Network for Tumor Biotherapy (NIBIT): Getting together to push the field forward
Michele Maio, Hugues JM Nicolay, Paolo Ascierto, Filippo Belardelli, Roberto Camerini, Mario P Colombo, Paola Queirolo, Ruggero Ridolfi, Vincenzo Russo, Lucia Anzalone, Ester Fonsatti, Giorgio Parmiani
NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols
Anna Bratasz, Karuppaiyah Selvendiran, Tomasz Wasowicz, Andrey Bobko, Valery V Khramtsov, Louis J Ignarro, Periannan Kuppusamy
Differential susceptibility of C57BL/6NCr and B6.Cg-Ptprca mice to commensal bacteria after whole body irradiation in translational bone marrow transplant studies
Raimon Duran-Struuck, Adam Hartigan, Shawn G Clouthier, Melissa C Dyson, Kathi Lowler, Erin Gatza, Isao Tawara, Tomomi Toubai, Elisabeth Weisiger, Kelly Hugunin, Pavan Reddy, John E Wilkinson
Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation
Michael A Pacanowski, Issam Zineh, Haihong Li, B Delia Johnson, Rhonda M Cooper-DeHoff, Vera Bittner, Dennis M McNamara, Barry L Sharaf, C Noel Bairey Merz, Carl J Pepine, Julie A Johnson
Transient T cell depletion causes regression of melanoma metastases
Mary Ann Rasku, Amy L Clem, Sucheta Telang, Beverly Taft, Kelly Gettings, Hana Gragg, Daniel Cramer, Sheron C Lear, Kelly M McMasters, Donald M Miller, Jason Chesney
Hypermethylated MAL gene – a silent marker of early colon tumorigenesis
Guro E Lind, Terje Ahlquist, Matthias Kolberg, Marianne Berg, Mette Eknæs, Miguel A Alonso, Anne Kallioniemi, Gunn I Meling, Rolf I Skotheim, Torleiv O Rognum, Espen Thiis-Evensen, Ragnhild A Lothe
Merger of Ayurveda and Tissue Culture-Based Functional Genomics: Inspirations from Systems Biology
Custer C Deocaris, Nashi Widodo, Renu Wadhwa, Sunil C Kaul
The pituitary tumor transforming gene 1 (PTTG-1): An immunological target for multiple myeloma
Maurizio Chiriva-Internati, Raffaele Ferrari, Madhavi Prabhakar, Yuefei Yu, Luigi Baglioni, Jorge Moreno, Nicoletta Gagliano, Nicola Portinaro, Marjorie R Jenkins, Eldo E Frezza, Fred Hardwicke, Nicholas D'Cunha, W Martin Kast, Everardo Cobos
Comparison between conventional and "clinical" assessment of experimental lung fibrosis
Kjetil Ask, Renee Labiris, Laszlo Farkas, Antje Moeller, Aaron Froese, Troy Farncombe, Grant B McClelland, Mark Inman, Jack Gauldie, Martin RJ Kolb
GM-CSF/IL-3/IL-5 receptor common β chain (CD131) expression as a biomarker of antigen-stimulated CD8+ T cells
Silvia Selleri, Sara Deola, Zoltan Pos, Ping Jin, Andrea Worschech, Stefanie L Slezak, Cristiano Rumio, Monica C Panelli, Dragan Maric, David F Stroncek, Ena Wang, Francesco M Marincola
Practical aspects in the management of hypokalemic periodic paralysis
Jacob O Levitt
Foxp3 expression in human cancer cells
Vaios Karanikas, Matthaios Speletas, Maria Zamanakou, Fani Kalala, Gedeon Loules, Theodora Kerenidi, Angeliki K Barda, Konstantinos I Gourgoulianis, Anastasios E Germenis
Preserving a legacy for our patients: The bedside-to-bench award in translational research
Francesco M Marincola
Whole tumor antigen vaccination using dendritic cells: Comparison of RNA electroporation and pulsing with UV-irradiated tumor cells
Fabian Benencia, Maria C Courrèges, George Coukos
Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma
Begoña Comin-Anduix, Yohan Lee, Jason Jalil, Alain Algazi, Pilar de la Rocha, Luis H Camacho, Viviana A Bozon, Cecile A Bulanhagui, Elisabeth Seja, Arturo Villanueva, Bradley R Straatsma, Antonio Gualberto, James S Economou, John A Glaspy, Jesus Gomez-Navarro, Antoni Ribas
Identification of heterogeneity among soft tissue sarcomas by gene expression profiles from different tumors
Keith M Skubitz, Stefan Pambuccian, J Carlos Manivel, Amy PN Skubitz
Clinical and immunological evaluation of anti-apoptosis protein, survivin-derived peptide vaccine in phase I clinical study for patients with advanced or recurrent breast cancer
Tetsuhiro Tsuruma, Yuji Iwayama, Tosei Ohmura, Tadashi Katsuramaki, Fumitake Hata, Tomohisa Furuhata, Koji Yamaguchi, Yasutoshi Kimura, Toshihiko Torigoe, Nobuhiko Toyota, Atsuhito Yagihashi, Yoshihiko Hirohashi, Hiroko Asanuma, Kumiko Shimozawa, Minoru Okazaki, Yasuhiro Mizushima, Naohiro Nomura, Noriyuki Sato, Koichi Hirata
Correlation between NK function and response to trastuzumab in metastatic breast cancer patients
Alessandra Beano, Elena Signorino, Andrea Evangelista, Davide Brusa, Marinella Mistrangelo, Maria Antonia Polimeni, Rosella Spadi, Michela Donadio, Libero Ciuffreda, Lina Matera
Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice
Lena A Basile, Timothy K Gallaher, Darryl Shibata, Joseph D Miller, Dan Douer
RETRACTED ARTICLE: Molecular analysis of the effects of Piroxicam and Cisplatin on mesothelioma cells growth and viability
Alessandra Verdina, Irene Cardillo, Angela Nebbioso, Rossella Galati, Simona Menegozzo, Lucia Altucci, Ada Sacchi, Alfonso Baldi
Treatment of esophageal tumors using high intensity intraluminal ultrasound: first clinical results
David Melodelima, Frederic Prat, Jacques Fritsch, Yves Theillere, Dominique Cathignol
Cytomegalovirus-specific T-cell responses and viral replication in kidney transplant recipients
Adrian Egli, Isabelle Binet, Simone Binggeli, Clemens Jäger, Alexis Dumoulin, Stefan Schaub, Juerg Steiger, Urban Sester, Martina Sester, Hans H Hirsch
Potential advantages of cell administration on the inflammatory response compared to standard ACE inhibitor treatment in experimental myocardial infarction
Michele M Ciulla, Elisa Montelatici, Stefano Ferrero, Paola Braidotti, Roberta Paliotti, Giuseppe Annoni, Elisa De Camilli, Giuseppe Busca, Luisa Chiappa, Paolo Rebulla, Fabio Magrini, Lorenza Lazzari
Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China
Weiyi Fang, Xin Li, Qingping Jiang, Zhen Liu, Huiling Yang, Shuang Wang, Siming Xie, Qiuzhen Liu, Tengfei Liu, Jing Huang, Weibing Xie, Zuguo Li, Yingdong Zhao, Ena Wang, Francesco M Marincola, Kaitai Yao
Pathways to ischemic neuronal cell death: are sex differences relevant?
Jesse T Lang, Louise D McCullough
Relative quantification of TCR Vbeta-chain families by real time PCR for identification of clonal T-cell populations
Sebastian Ochsenreither, Alberto Fusi, Antonia Busse, Dirk Nagorsen, David Schrama, Jürgen Becker, Eckhard Thiel, Ulrich Keilholz
Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic?
Irina Kerkis, Carlos E Ambrosio, Alexandre Kerkis, Daniele S Martins, Eder Zucconi, Simone AS Fonseca, Rosa M Cabral, Carlos MC Maranduba, Thais P Gaiad, Adriana C Morini, Natassia M Vieira, Marina P Brolio, Osvaldo A Sant'Anna, Maria A Miglino, Mayana Zatz
Different outcome of six homozygotes for prothrombin A20210A gene variant
Pierpaolo Di Micco, Rosanna Di Fiore, Alferio Niglio, Sandro Quaranta, Antonella Angiolillo, Giuseppe Cardillo, Giuseppe Castaldo
Exosomes as a tumor immune escape mechanism: possible therapeutic implications
Thomas E Ichim, Zhaohui Zhong, Shalesh Kaushal, Xiufen Zheng, Xiubao Ren, Xishan Hao, James A Joyce, Harold H Hanley, Neil H Riordan, James Koropatnick, Vladimir Bogin, Boris R Minev, Wei-Ping Min, Richard H Tullis
Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in Non-Small Cell Lung Cancer
Felicita Baratelli, Hiroko Takedatsu, Saswati Hazra, Katherine Peebles, Jie Luo, Pam S Kurimoto, Gang Zeng, Raj K Batra, Sherven Sharma, Steven M Dubinett, Jay M Lee
Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis
Ping Jin, Ena Wang, Jiaqiang Ren, Richard Childs, Jeong Won Shin, Hanh Khuu, Francesco M Marincola, David F Stroncek
Training the next generation of pluripotent stem cell researchers
Philip Hitchins Schwartz
Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery
Nathalie Scholler, Jennifer A Gross, Barbara Garvik, Lance Wells, Yan Liu, Christian M Loch, Arturo B Ramirez, Martin W McIntosh, Paul D Lampe, Nicole Urban
Short- and long-term outcomes of single bare metal stent versus drug eluting stent in nondiabetic patients with a simple de novo lesion in the middle and large vessel
Yue-jin Yang, Sheng Kang, Bo Xu, Ji-lin Chen, Shu-bin Qiao, Xue-wen Qin, Min Yao, Jue Chen, Yong-jian Wu, Hai-bo Liu, Jin-qing Yuan, Shi-jie You, Jian-jun Li, Jun Dai, Run-lin Gao
Zoledronic acid increases docetaxel cytotoxicity through pMEK and Mcl-1 inhibition in a hormone-sensitive prostate carcinoma cell line
Francesco Fabbri, Giovanni Brigliadori, Silvia Carloni, Paola Ulivi, Ivan Vannini, Anna Tesei, Rosella Silvestrini, Dino Amadori, Wainer Zoli
The prediction of interferon treatment effects based on time series microarray gene expression profiles
Tao Huang, Kang Tu, Yu Shyr, Chao-Chun Wei, Lu Xie, Yi-Xue Li
Allogeneic endometrial regenerative cells: An "Off the shelf solution" for critical limb ischemia?
Michael P Murphy, Hao Wang, Amit N Patel, Suman Kambhampati, Niren Angle, Kyle Chan, Annette M Marleau, Andrew Pyszniak, Ewa Carrier, Thomas E Ichim, Neil H Riordan
Non-compliance is the predominant cause of aspirin resistance in chronic coronary arterial disease patients
Kenneth A Schwartz, Dianne E Schwartz, Kimberly Barber, Mathew Reeves, Anthony C De Franco
'Aspirin resistance' or treatment non-compliance: Which is to blame for cardiovascular complications?
Eduard Shantsila, Gregory YH Lip
Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda
Bhavana Prasher, Sapna Negi, Shilpi Aggarwal, Amit K Mandal, Tav P Sethi, Shailaja R Deshmukh, Sudha G Purohit, Shantanu Sengupta, Sangeeta Khanna, Farhan Mohammad, Gaurav Garg, Samir K Brahmachari, Mitali Mukerji
Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion
Raffaele Badolato, Claudia Ghidini, Fabio Facchetti, Federico Serana, Alessandra Sottini, Marco Chiarini, Elena Spinelli, Silvia Lonardi, Alessandro Plebani, Luigi Caimi, Luisa Imberti
Anti-angiogenic effect of high doses of ascorbic acid
Nina A Mikirova, Thomas E Ichim, Neil H Riordan
In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells
Shigeo Koido, Sadamu Homma, Eiichi Hara, Makoto Mitsunaga, Yoshihisa Namiki, Akitaka Takahara, Eijiro Nagasaki, Hideo Komita, Yukiko Sagawa, Toshifumi Ohkusa, Kiyotaka Fujise, Jianlin Gong, Hisao Tajiri
Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines
Alex J Eustace, John Crown, Martin Clynes, Norma O'Donovan
Transplantation of vascular cells derived from human embryonic stem cells contributes to vascular regeneration after stroke in mice
Naofumi Oyamada, Hiroshi Itoh, Masakatsu Sone, Kenichi Yamahara, Kazutoshi Miyashita, Kwijun Park, Daisuke Taura, Megumi Inuzuka, Takuhiro Sonoyama, Hirokazu Tsujimoto, Yasutomo Fukunaga, Naohisa Tamura, Kazuwa Nakao
Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin
Si Ming Xie, Wei Yi Fang, Zhen Liu, Shuang Xi Wang, Xin Li, Teng Fei Liu, Wei Bing Xie, Kai Tai Yao
Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells
Yuefei Yu, Petra Pilgrim, Juqiang Yan, Wei Zhou, Marjorie Jenkins, Nicoletta Gagliano, Klaus Bumm, Martin Cannon, Aldo Milzani, Isabella Dalle-Donne, W Martin Kast, Everardo Cobos, Maurizio Chiriva-Internati
Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis
María Valcárcel, Beatriz Arteta, Arrate Jaureguibeitia, Aritz Lopategi, Iñigo Martínez, Lorea Mendoza, Francisco J Muruzabal, Clarisa Salado, Fernando Vidal-Vanaclocha
Whole blood assessment of antigen specific cellular immune response by real time quantitative PCR: a versatile monitoring and discovery tool
Elke Schultz-Thater, Daniel M Frey, Daniela Margelli, Nermin Raafat, Chantal Feder-Mengus, Giulio C Spagnoli, Paul Zajac
Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells
Elizabeth A DiBlasio-Smith, Maya Arai, Elaine M Quinet, Mark J Evans, Tad Kornaga, Michael D Basso, Liang Chen, Irene Feingold, Anita R Halpern, Qiang-Yuan Liu, Ponnal Nambi, Dawn Savio, Shuguang Wang, William M Mounts, Jennifer A Isler, Anna M Slager, Michael E Burczynski, Andrew J Dorner, Edward R LaVallie
Use of high throughput qPCR screening to rapidly clone low frequency tumour specific T-cells from peripheral blood for adoptive immunotherapy
Udai S Kammula, Oscar K Serrano
Validation of a HLA-A2 tetramer flow cytometric method, IFNgamma real time RT-PCR, and IFNgamma ELISPOT for detection of immunologic response to gp100 and MelanA/MART-1 in melanoma patients
Yuanxin Xu, Valerie Theobald, Crystal Sung, Kathleen DePalma, Laura Atwater, Keirsten Seiger, Michael A Perricone, Susan M Richards
Adjuvant therapy of melanoma with interferon: lessons of the past decade
Paolo A Ascierto, John M Kirkwood
More insights into the immunosuppressive potential of tumor exosomes
Veronica Huber, Paola Filipazzi, Manuela Iero, Stefano Fais, Licia Rivoltini
"Sequencing-grade" screening for BRCA1 variants by oligo-arrays
Alessandro Monaco, Filippo Menolascina, Yingdong Zhao, Stefania Tommasi, Marianna Sabatino, Ross Fasano, Angelo Paradiso, Francesco M Marincola, Ena Wang
Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer
Alessandro Passardi, Lorenzo Cecconetto, Monia Dall'Agata, Claudio Dazzi, Enzo Pasquini, Giovanni Oliverio, Federica Zumaglini, Wainer Zoli, Oriana Nanni, Carlo Milandri, Giovanni Luca Frassineti, Dino Amadori
Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first 10 weeks of treatment
Milton W Taylor, Takuma Tsukahara, Jeanette N McClintick, Howard J Edenberg, Paul Kwo
Implantation of neural stem cells embedded in hyaluronic acid and collagen composite conduit promotes regeneration in a rabbit facial nerve injury model
Han Zhang, Yue Teng Wei, Kam Sze Tsang, Chong Ran Sun, Jin Li, Hua Huang, Fu Zhai Cui, Yi Hua An
Hypothetical membrane mechanisms in essential tremor
Aasef G Shaikh, Kenichiro Miura, Lance M Optican, Stefano Ramat, Robert M Tripp, David S Zee
Gene expression profiling for molecular distinction and characterization of laser captured primary lung cancers
Astrid Rohrbeck, Judith Neukirchen, Michael Rosskopf, Guillermo G Pardillos, Helene Geddert, Andreas Schwalen, Helmut E Gabbert, Arndt von Haeseler, Gerald Pitschke, Matthias Schott, Ralf Kronenwett, Rainer Haas, Ulrich-Peter Rohr
Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients
Jessie Z Yu, Melanie A Warycha, Paul J Christos, Farbod Darvishian, Herman Yee, Hideko Kaminio, Russell S Berman, Richard L Shapiro, Michael T Buckley, Leonard F Liebes, Anna C Pavlick, David Polsky, Peter C Brooks, Iman Osman
Tremorgenesis: a new conceptual scheme using reciprocally innervated circuit of neurons
Mario Manto
Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?
Giovanni Tarantino, Paolo Conca, Antonio Riccio, Marianna Tarantino, Matteo N Di Minno, Domenico Chianese, Fabrizio Pasanisi, Franco Contaldo, Francesco Scopacasa, Domenico Capone
Detection of postoperative granulation tissue with an ICG-enhanced integrated OI-/X-ray System
Reinhard Meier, Sophie Boddington, Christian Krug, Frank L Acosta, Daniel Thullier, Tobias D Henning, Elizabeth J Sutton, Sidhartha Tavri, Jeffrey C Lotz, Heike E Daldrup-Link
Molecular Etiology of Hearing Impairment in Inner Mongolia: mutations in SLC26A4 gene and relevant phenotype analysis
Pu Dai, Yongyi Yuan, Deliang Huang, Xiuhui Zhu, Fei Yu, Dongyang Kang, Huijun Yuan, Bailin Wu, Dongyi Han, Lee-Jun C Wong
Primary cultured fibroblasts derived from patients with chronic wounds: a methodology to produce human cell lines and test putative growth factor therapy such as GMCSF
Harold Brem, Michael S Golinko, Olivera Stojadinovic, Arber Kodra, Robert F Diegelmann, Sasa Vukelic, Hyacinth Entero, Donald L Coppock, Marjana Tomic-Canic
Validation of a flow cytometry based chemokine internalization assay for use in evaluating the pharmacodynamic response to a receptor antagonist
Timothy Wyant, Alan Lackey, Marie Green
A highly invasive human glioblastoma pre-clinical model for testing therapeutics
Qian Xie, Ryan Thompson, Kim Hardy, Lisa DeCamp, Bree Berghuis, Robert Sigler, Beatrice Knudsen, Sandra Cottingham, Ping Zhao, Karl Dykema, Brian Cao, James Resau, Rick Hay, George F Vande Woude
Interdependency of CEACAM-1, -3, -6, and -8 induced human neutrophil adhesion to endothelial cells
Keith M Skubitz, Amy PN Skubitz
Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells
Christopher D Scharer, Noelani Laycock, Adeboye O Osunkoya, Sanjay Logani, John F McDonald, Benedict B Benigno, Carlos S Moreno
Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells
Hemant Sarin, Ariel S Kanevsky, Haitao Wu, Kyle R Brimacombe, Steve H Fung, Alioscka A Sousa, Sungyoung Auh, Colin M Wilson, Kamal Sharma, Maria A Aronova, Richard D Leapman, Gary L Griffiths, Matthew D Hall
A systematic approach to biomarker discovery; Preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers"
Lisa H Butterfield, Mary L Disis, Bernard A Fox, Peter P Lee, Samir N Khleif, Magdalena Thurin, Giorgio Trinchieri, Ena Wang, Jon Wigginton, Damien Chaussabel, George Coukos, Madhav Dhodapkar, Leif Håkansson, Sylvia Janetzki, Thomas O Kleen, John M Kirkwood, Cristina Maccalli, Holden Maecker, Michele Maio, Anatoli Malyguine, Giuseppe Masucci, A Karolina Palucka, Douglas M Potter, Antoni Ribas, Licia Rivoltini, Dolores Schendel, Barbara Seliger, Senthamil Selvan, Craig L Slingluff Jr, David F Stroncek, Howard Streicher, Xifeng Wu, Benjamin Zeskind, Yingdong Zhao, Mai-Britt Zocca, Heinz Zwierzina, Francesco M Marincola