Ausgabe 1/2010
Inhalt (140 Artikel)
Immune and hemorheological changes in Chronic Fatigue Syndrome
Ekua W Brenu, Donald R Staines, Oguz K Baskurt, Kevin J Ashton, Sandra B Ramos, Rhys M Christy, Sonya M Marshall-Gradisnik
A quantitative real time PCR method to analyze T cell receptor Vβ subgroup expansion by staphylococcal superantigens
Keun Seok Seo, Joo Youn Park, David S Terman, Gregory A Bohach
Introducing the Immunovirology Section of Journal of Translational Medicine
Luigi Buonaguro
Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies
Ping Jin, Tae Hee Han, Jiaqiang Ren, Stefanie Saunders, Ena Wang, Francesco M Marincola, David F Stroncek
Mutation or loss of Wilms' tumor gene 1 (WT1) are not major reasons for immune escape in patients with AML receiving WT1 peptide vaccination
Antonia Busse, Anne Letsch, Carmen Scheibenbogen, Anika Nonnenmacher, Sebastian Ochsenreither, Eckhard Thiel, Ulrich Keilholz
Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity
Kelly L Brown, Reza Falsafi, Winnie Kum, Pamela Hamill, Jennifer L Gardy, Donald J Davidson, Stuart Turvey, Brett B Finlay, David P Speert, Robert EW Hancock
Boosting high-intensity focused ultrasound-induced anti-tumor immunity using a sparse-scan strategy that can more effectively promote dendritic cell maturation
Fang Liu, Zhenlin Hu, Lei Qiu, Chun Hui, Chao Li, Pei Zhong, Junping Zhang
A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma
Osama E Rahma, Ed Ashtar, Ramy Ibrahim, Antoun Toubaji, Barry Gause, Vincent E Herrin, W Marston Linehan, Seth M Steinberg, Frank Grollman, George Grimes, Sarah A Bernstein, Jay A Berzofsky, Samir N Khleif
Autologous tumor-derived heat-shock protein peptide complex-96 (HSPPC-96) in patients with metastatic melanoma
Omar Eton, Merrick I Ross, Mary Jo East, Paul F Mansfield, Nicholas Papadopoulos, Julie A Ellerhorst, Agop Y Bedikian, Jeffrey E Lee
Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy
Vladia Monsurrò, Stefania Beghelli, Richard Wang, Stefano Barbi, Silvia Coin, Giovanni Di Pasquale, Samantha Bersani, Monica Castellucci, Claudio Sorio, Stefano Eleuteri, Andrea Worschech, Jay A Chiorini, Paolo Pederzoli, Harvey Alter, Francesco M Marincola, Aldo Scarpa
Detection of epithelial apoptosis in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis
Raquel F Leal, Maria de Lourdes S Ayrizono, Marciane Milanski, João J Fagundes, Juliana C Moraes, Luciana R Meirelles, Lício A Velloso, Cláudio SR Coy
Translational Medicine - doing it backwards
Robert B Nussenblatt, Francesco M Marincola, Alan N Schechter
The density of macrophages in the invasive front is inversely correlated to liver metastasis in colon cancer
Qiang Zhou, Rui-Qing Peng, Xiao-Jun Wu, Qing Xia, Jing-Hui Hou, Ya Ding, Qi-Ming Zhou, Xing Zhang, Zhi-Zhong Pang, De-Sen Wan, Yi-Xin Zeng, Xiao-Shi Zhang
Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors
Chelsey Woodrum, Alison Nobil, Sandra L Dabora
TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status
Marta Herreros-Villanueva, Pilar Muñiz, Carlos García-Girón, Mónica Cavia-Saiz, María J Coma del Corral
Lasers, stem cells, and COPD
Feng Lin, Steven F Josephs, Doru T Alexandrescu, Famela Ramos, Vladimir Bogin, Vincent Gammill, Constantin A Dasanu, Rosalia De Necochea-Campion, Amit N Patel, Ewa Carrier, David R Koos
miR-17-92 expression in differentiated T cells - implications for cancer immunotherapy
Kotaro Sasaki, Gary Kohanbash, Aki Hoji, Ryo Ueda, Heather A McDonald, Todd A Reinhart, Jeremy Martinson, Michael T Lotze, Francesco M Marincola, Ena Wang, Mitsugu Fujita, Hideho Okada
Immune signatures in human PBMCs of idiotypic vaccine for HCV-related lymphoproliferative disorders
Luigi Buonaguro, Annacarmen Petrizzo, Marialina Tornesello, Maria Napolitano, Debora Martorelli, Giuseppe Castello, Gerardo Beneduce, Amalia De Renzo, Oreste Perrella, Luca Romagnoli, Vitor Sousa, Valli De Re, Riccardo Dolcetti, Franco M Buonaguro
Increased shedding of HU177 correlates with worse prognosis in primary melanoma
Heather K Hamilton, Amy E Rose, Paul J Christos, Richard L Shapiro, Russell S Berman, Madhu Mazumdar, Michelle W Ma, Daniel Krich, Leonard Liebes, Peter C Brooks, Iman Osman
A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899
Robert S DiPaola, Yu-Hui Chen, Mark Stein, David Vaughn, Linda Patrick-Miller, Michael Carducci, Bruce Roth, Eileen White, George Wilding
Genomic aberrations in borderline ovarian tumors
Francesca Micci, Lisbeth Haugom, Terje Ahlquist, Hege K Andersen, Vera M Abeler, Ben Davidson, Claes G Trope, Ragnhild A Lothe, Sverre Heim
Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells
Francesca M Rossi, Maria Ilaria Del Principe, Davide Rossi, Maria Irno Consalvo, Fabrizio Luciano, Antonella Zucchetto, Pietro Bulian, Riccardo Bomben, Michele Dal Bo, Marco Fangazio, Dania Benedetti, Massimo Degan, Gianluca Gaidano, Giovanni Del Poeta, Valter Gattei
Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction
Claus S Sondergaard, David A Hess, Dustin J Maxwell, Carla Weinheimer, Ivana Rosová, Michael H Creer, David Piwnica-Worms, Attila Kovacs, Lene Pedersen, Jan A Nolta
Bridging the Divide between Science and Journalism
Laura Van Eperen, Francesco M Marincola, Jennifer Strohm
Microrna profiling analysis of differences between the melanoma of young adults and older adults
Drazen M Jukic, Uma NM Rao, Lori Kelly, Jihad S Skaf, Laura M Drogowski, John M Kirkwood, Monica C Panelli
Papillomavirus pseudovirions packaged with the L2 gene induce cross-neutralizing antibodies
Nicolas Combelas, Emilie Saussereau, Maxime JJ Fleury, Tatiana Ribeiro, Julien Gaitan, Diego F Duarte-Forero, Pierre Coursaget, Antoine Touzé
Abdominal irradiation modulates 5-Fluorouracil pharmacokinetics
Chen-Hsi Hsieh, Yen-Ju Hsieh, Chia-Yuan Liu, Hung-Chi Tai, Yu-Chuen Huang, Pei-Wei Shueng, Le-Jung Wu, Li-Ying Wang, Tung-Hu Tsai, Yu-Jen Chen
Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma
Jing Chen, Chun-Fang Hu, Jing-Hui Hou, Qiong Shao, Li-Xu Yan, Xiao-Feng Zhu, Yi-Xin Zeng, Jian-Yong Shao
Cell and gene therapies: moving from research to clinic
David F Stroncek, Raj K Puri
Effect of dipterinyl calcium pentahydrate on hepatitis B virus replication in transgenic mice
Phillip Moheno, John Morrey, Dietmar Fuchs
"Hypoxia-induced down-regulation of microRNA-449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression"
Michaela Muth, Katharina Theophile, Kais Hussein, Christoph Jacobi, Hans Kreipe, Oliver Bock
Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects
Nina A Mikirova, James A Jackson, Ron Hunninghake, Julian Kenyon, Kyle WH Chan, Cathy A Swindlehurst, Boris Minev, Amit N Patel, Michael P Murphy, Leonard Smith, Famela Ramos, Thomas E Ichim, Neil H Riordan
Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients
Sebastian Ochsenreither, Alberto Fusi, Susanne Wojtke, Antonia Busse, Natascha C Nüssler, Eckhard Thiel, Ulrich Keilholz, Dirk Nagorsen
Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab
Carla Campanella, Marcella Mottolese, Anna Cianciulli, Angela Torsello, Roberta Merola, Isabella Sperduti, Elisa Melucci, Salvatore Conti, Maria Grazia Diodoro, Massimo Zeuli, Giancarlo Paoletti, Francesco Cognetti, Carlo Garufi
Oxidative stress in NSC-741909-induced apoptosis of cancer cells
Xiaoli Wei, Wei Guo, Shuhong Wu, Li Wang, Peng Huang, Jinsong Liu, Bingliang Fang
Melanoma: A model for testing new agents in combination therapies
Paolo A Ascierto, Howard Z Streicher, Mario Sznol
Differential sensitivity of melanoma cell lines with BRAF V600E mutation to the specific Raf inhibitor PLX4032
Jonas N Søndergaard, Ramin Nazarian, Qi Wang, Deliang Guo, Teli Hsueh, Stephen Mok, Hooman Sazegar, Laura E MacConaill, Jordi G Barretina, Sarah M Kehoe, Narsis Attar, Erika von Euw, Jonathan E Zuckerman, Bartosz Chmielowski, Begoña Comin-Anduix, Richard C Koya, Paul S Mischel, Roger S Lo, Antoni Ribas
Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits
Antonia Radaelli, Eleana Pozzi, Sole Pacchioni, Carlo Zanotto, Carlo De Giuli Morghen
Correlation of pharmacodynamic activity, pharmacokinetics, and anti-product antibody responses to anti-IL-21R antibody therapeutics following IV administration to cynomolgus monkeys
Yulia Vugmeyster, Scott Allen, Pamela Szklut, Andrea Bree, Mark Ryan, Margery Ma, Vikki Spaulding, Deborah Young, Heath Guay, Laird Bloom, Michael W Leach, Margot O'Toole, Karissa Adkins
Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice
Jennifer A Westwood, Phillip K Darcy, Preethi Mayura Guru, Janelle Sharkey, Hollie J Pegram, Sally M Amos, Mark J Smyth, Michael H Kershaw
Non-monotonic changes in clonogenic cell survival induced by disulphonated aluminum phthalocyanine photodynamic treatment in a human glioma cell line
Seema Gupta, Bilikere S Dwarakanath, K Muralidhar, Tulay Koru-Sengul, Viney Jain
HSF1 overexpression enhances oncolytic effect of replicative adenovirus
Cheng Wang, Zhehao Dai, Rong Fan, Youwen Deng, Guohua Lv, Guangxiu Lu
CCL20/CCR6 expression profile in pancreatic cancer
Claudia Rubie, Vilma Oliveira Frick, Pirus Ghadjar, Mathias Wagner, Henner Grimm, Benjamin Vicinus, Christoph Justinger, Stefan Graeber, Martin K Schilling
Transcriptional responses in the adaptation to ischaemia-reperfusion injury: a study of the effect of ischaemic preconditioning in total knee arthroplasty patients
Terence Murphy, Pauline M Walsh, Peter P Doran, Kevin J Mulhall
Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients
Yangqiu Li, Suxia Geng, Qingsong Yin, Shaohua Chen, Lijian Yang, Xiuli Wu, Bo Li, Xin Du, Christian A Schmidt, Grzegorz K Przybylski
Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients
Stefano Gambardella, Fabrizio Rinaldi, Saverio M Lepore, Antonella Viola, Emanuele Loro, Corrado Angelini, Lodovica Vergani, Giuseppe Novelli, Annalisa Botta
Toll-like receptor 9 polymorphisms influence mother-to-child transmission of human immunodeficiency virus type 1
Elisabetta Ricci, Sandro Malacrida, Marisa Zanchetta, Ilaria Mosconi, Marco Montagna, Carlo Giaquinto, Anita De Rossi
Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody
Yongjing Guo, Andrew A Hill, Renee C Ramsey, Frederick W Immermann, Christopher Corcoran, Deborah Young, Edward R LaVallie, Mark Ryan, Theresa Bechard, Richard Pfeifer, Garvin Warner, Marcia Bologna, Laird Bloom, Margot O'Toole
Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood
Maya Arai, Sadhana Jain, Amy A Weaver, Andrew A Hill, Yongjing Guo, Andrea G Bree, Michael F Smith Jr, Scott W Allen, Edward R LaVallie, Deborah Young, Laird Bloom, Karissa Adkins, Margot O'Toole
FRET microscopy autologous tumor lysate processing in mature dendritic cell vaccine therapy
Laura Fiammenghi, Valentina Ancarani, Tilman Rosales, Jay R Knutson, Massimiliano Petrini, Anna Maria Granato, Elena Pancisi, Laura Ridolfi, Ruggero Ridolfi, Angela Riccobon, Paolo Neyroz
Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial
Håkan Norell, Isabel Poschke, Jehad Charo, Wei Z Wei, Courtney Erskine, Marie P Piechocki, Keith L Knutson, Jonas Bergh, Elisabet Lidbrink, Rolf Kiessling
The application of adjuvant autologous antravesical macrophage cell therapy vs. BCG in non-muscle invasive bladder cancer: a multicenter, randomized trial
Maximilian Burger, Nicolas Thiounn, Stefan Denzinger, Jozsef Kondas, Gerard Benoit, Manuel S Chapado, Fernando J Jimenz-Cruz, Laszlo Kisbenedek, Zoltán Szabo, Domján Zsolt, Marc O Grimm, Imre Romics, Joachim W Thüroff, Tamas Kiss, Bertrand Tombal, Manfred Wirth, Marc Munsell, Bonnie Mills, Tung Koh, Jeff Sherman
Strategy Escalation: An emerging paradigm for safe clinical development of T cell gene therapies
Richard Paul Junghans
Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies
Luca Sigalotti, Alessia Covre, Elisabetta Fratta, Giulia Parisi, Francesca Colizzi, Aurora Rizzo, Riccardo Danielli, Hugues JM Nicolay, Sandra Coral, Michele Maio
Proton dynamics in cancer
Veronica Huber, Angelo De Milito, Salvador Harguindey, Stephan J Reshkin, Miriam L Wahl, Cyril Rauch, Antonio Chiesi, Jacques Pouysségur, Robert A Gatenby, Licia Rivoltini, Stefano Fais
In vivo evidence of htid suppressive activity on ErbB-2 in breast cancers over expressing the receptor
Ursula Kurzik-Dumke, Manuela Hörner, Maria R Nicotra, Michael Koslowski, Pier G Natali
The effect of an autologous cellular gel-matrix integrated implant system on wound healing
Caroline R Weinstein-Oppenheimer, Alexis R Aceituno, Donald I Brown, Cristian Acevedo, Ricardo Ceriani, Miguel A Fuentes, Fernando Albornoz, Carlos F Henríquez-Roldán, Patricio Morales, Claudio Maclean, Sergio M Tapia, Manuel E Young
Introducing the Cancer Microenvironment Section of Journal of Translational Medicine
Fernando Vidal-Vanaclocha, Isaac P Witz
Ezrin promotes invasion and metastasis of pancreatic cancer cells
Yunxiao Meng, Zhaohui Lu, Shuangni Yu, Qiang Zhang, Yihui Ma, Jie Chen
An exploratory investigation of the influence of publication on translational medicine research
Lisa J Douet, Danielle Preedy, Vaughan Thomas, Ian A Cree
Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats
Steve Leu, Yu-Chun Lin, Chun-Man Yuen, Chia-Hung Yen, Ying-Hsien Kao, Cheuk-Kwan Sun, Hon-Kan Yip
Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic cardiomyopathy: AT1R as a potential modifier
Eliecer Coto, María Palacín, María Martín, Mónica G Castro, Julián R Reguero, Cristina García, José R Berrazueta, César Morís, Blanca Morales, Francisco Ortega, Ana I Corao, Marta Díaz, Beatriz Tavira, Victoria Alvarez
The status of clinical trials: Cause for concern
Robert B Nussenblatt, Curtis L Meinert
Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer
Monika Pietrowska, Joanna Polanska, Lukasz Marczak, Katarzyna Behrendt, Elzbieta Nowicka, Maciej Stobiecki, Andrzej Polanski, Rafal Tarnawski, Piotr Widlak
Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032
Jill C Rubinstein, Mario Sznol, Anna C Pavlick, Stephan Ariyan, Elaine Cheng, Antonella Bacchiocchi, Harriet M Kluger, Deepak Narayan, Ruth Halaban
Effective knowledge management in translational medicine
Sándor Szalma, Venkata Koka, Tatiana Khasanova, Eric D Perakslis
Evaluation of normalization methods for two-channel microRNA microarrays
Yingdong Zhao, Ena Wang, Hui Liu, Melissa Rotunno, Jill Koshiol, Francesco M Marincola, Maria Teresa Landi, Lisa M McShane
Copy number and gene expression differences between African American and Caucasian American prostate cancer
Amy E Rose, Jaya M Satagopan, Carole Oddoux, Qin Zhou, Ruliang Xu, Adam B Olshen, Jessie Z Yu, Atreya Dash, Jerome Jean-Gilles, Victor Reuter, William L Gerald, Peng Lee, Iman Osman
First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP321 (LAG-3Ig) enhances immune responses and antitumor activity
Chrystelle Brignone, Maya Gutierrez, Fawzia Mefti, Etienne Brain, Rosana Jarcau, Frédérique Cvitkovic, Nabil Bousetta, Jacques Medioni, Joseph Gligorov, Caroline Grygar, Manon Marcu, Frédéric Triebel
Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference
Britta Wahren, Priscilla Biswas, Marie Borggren, Adam Coleman, Kelly Da Costa, Winni De Haes, Tessa Dieltjens, Stefania Dispinseri, Katrijn Grupping, David Hallengärd, Julia Hornig, Katja Klein, Lara Mainetti, Paolo Palma, Marc Reudelsterz, Janna Seifried, Philippe Selhorst, Annette Sköld, Marit J van Gils, Caroline Weber, Robin Shattock, Gabriella Scarlatti
Low temperature of radiofrequency ablation at the target sites can facilitate rapid progression of residual hepatic VX2 carcinoma
Shan Ke, Xue-mei Ding, Jian Kong, Jun Gao, Shao-hong Wang, Yan Cheng, Wen-bing Sun
Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models
Isabel Cardoso, Diana Martins, Tania Ribeiro, Giampaolo Merlini, Maria João Saraiva
Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions
Wan-Zhang Yang, Yun Zhang, Fang Wu, Wei-Ping Min, Boris Minev, Min Zhang, Xiao-Ling Luo, Famela Ramos, Thomas E Ichim, Neil H Riordan, Xiang Hu
Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-α 2b treatment
Paolo A Ascierto, Maria Napolitano, Egidio Celentano, Ester Simeone, Giusy Gentilcore, Antonio Daponte, Mariaelena Capone, Corrado Caracò, Rosa Calemma, Gerardo Beneduce, Margherita Cerrone, Vincenzo De Rosa, Giuseppe Palmieri, Giuseppe Castello, John M Kirkwood, Francesco M Marincola, Nicola Mozzillo
Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke
Chongran Sun, Han Zhang, Jin Li, Hua Huang, Hongbin Cheng, Yajie Wang, Ping Li, Yihua An
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer
Åsa Ehlén, Donal J Brennan, Björn Nodin, Darran P O'Connor, Jakob Eberhard, Maria Alvarado-Kristensson, Ian B Jeffrey, Jonas Manjer, Jenny Brändstedt, Mathias Uhlén, Fredrik Pontén, Karin Jirström
Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: a histologic and immunophenotypic analysis
Jochen T Schaefer, James W Patterson, Donna H Deacon, Mark E Smolkin, Gina R Petroni, Emily M Jackson, Craig L Slingluff Jr
Adenoviruses with an αvβ integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer metastases
Sergio Lavilla-Alonso, Gerd Bauerschmitz, Usama Abo-Ramadan, Juha Halavaara, Sophie Escutenaire, Iulia Diaconu, Turgut Tatlisumak, Anna Kanerva, Akseli Hemminki, Sari Pesonen
Anti-CDC25B autoantibody predicts poor prognosis in patients with advanced esophageal squamous cell carcinoma
Jun Dong, Bo-hang Zeng, Li-hua Xu, Jun-ye Wang, Man-Zhi Li, Mu-sheng Zeng, Wan-li Liu
Erratum to: Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference
Britta Wahren, Priscilla Biswas, Marie Borggren, Adam Coleman, Kelly Da Costa, Winni De Haes, Tessa Dieltjens, Stefania Dispinseri, Katrijn Grupping, David Hallengärd, Julia Hornig, Katja Klein, Lara Mainetti, Paolo Palma, Marc Reudelsterz, Janna Seifried, Philippe Selhorst, Annette Sköld, Hannes Uchtenhagen, Marit J van Gils, Caroline Weber, Robin Shattock, Gabriella Scarlatti
One Step Nucleic Acid Amplification (OSNA) - a new method for lymph node staging in colorectal carcinomas
Roland S Croner, Vera Schellerer, Helene Demund, Claus Schildberg, Thomas Papadopulos, Elisabeth Naschberger, Michael Stürzl, Klaus E Matzel, Werner Hohenberger, Anne Schlabrakowski
Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100-derived epitope peptide restricted to HLA-A*2402
Toshiyuki Baba, Marimo Sato-Matsushita, Akira Kanamoto, Akihiko Itoh, Naoki Oyaizu, Yusuke Inoue, Yutaka Kawakami, Hideaki Tahara
Role of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells
Joo Weon Lim, Hyeyoung Kim
Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in lung cancer
Mónica Castro, Laura Grau, Patricia Puerta, Liliana Gimenez, Julio Venditti, Silvia Quadrelli, Marta Sánchez-Carbayo
cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis
Mark L Parrish, Chris Wright, Yarek Rivers, David Argilla, Heather Collins, Brendan Leeson, Andrey Loboda, Michael Nebozhyn, Matthew J Marton, Serguei Lejnine
Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy
Yu-Chun Lin, Steve Leu, Cheuk-Kwan Sun, Chia-Hung Yen, Ying-Hsien Kao, Li-Teh Chang, Tzu-Hsien Tsai, Sarah Chua, Morgan Fu, Sheung-Fat Ko, Chiung-Jen Wu, Fan-Yen Lee, Hon-Kan Yip
Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma
Antoni Ribas, Luis H Camacho, Sun Min Lee, Evan M Hersh, Charles K Brown, Jon M Richards, Maria Jovie Rodriguez, Victor G Prieto, John A Glaspy, Denise K Oseguera, Jackie Hernandez, Arturo Villanueva, Bartosz Chmielowski, Peggie Mitsky, Nadège Bercovici, Ernesto Wasserman, Didier Landais, Merrick I Ross
Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation
Maja Bürdek, Stefani Spranger, Susanne Wilde, Bernhard Frankenberger, Dolores J Schendel, Christiane Geiger
Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma
Sumana Mukherjee, Mark J Roth, Sanford M Dawsey, Wusheng Yan, Jaime Rodriguez-Canales, Heidi S Erickson, Nan Hu, Alisa M Goldstein, Philip R Taylor, Annely M Richardson, Michael A Tangrea, Rodrigo F Chuaqui, Michael R Emmert-Buck
S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)
Donald Lavelle, Yogen Saunthararajah, Kestis Vaitkus, Mahipal Singh, Virryan Banzon, Pasit Phiasivongsva, Sanjeev Redkar, Sarath Kanekal, David Bearss, Chongtie Shi, Roger Inloes, Joseph DeSimone
Patients with chronic fatigue syndrome performed worse than controls in a controlled repeated exercise study despite a normal oxidative phosphorylation capacity
Ruud CW Vermeulen, Ruud M Kurk, Frans C Visser, Wim Sluiter, Hans R Scholte
Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma
Nan Ge, Huan-Xin Lin, Xiang-Sheng Xiao, Ling Guo, Hui-Min Xu, Xin Wang, Ting Jin, Xiu-Yu Cai, Yi Liang, Wei-Han Hu, Tiebang Kang
The "Excellence in Translational Medicine" and "Bedside-to-Bench" Awards 2008-09
Richard J Ablin, Francesco M Marincola, Pier Giorgio Natali
Expression of Msx-1 is suppressed in bisphosphonate associated osteonecrosis related jaw tissue-etiopathology considerations respecting jaw developmental biology-related unique features
Falk Wehrhan, Peter Hyckel, Jutta Ries, Phillip Stockmann, Emeka Nkenke, Karl A Schlegel, Friedrich W Neukam, Kerstin Amann
Rapid induction of autoantibodies during ARDS and septic shock
Peter D Burbelo, Nitin Seam, Sandra Groot, Kathryn H Ching, Brian L Han, G Umberto Meduri, Michael J Iadarola, Anthony F Suffredini
Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice
Claudia Raja Gabaglia, Alexandra DeLaney, Jennifer Gee, Ramesh Halder, Frank L Graham, Jack Gauldie, Eli E Sercarz, Todd A Braciak
MMP-1 is a (pre-)invasive factor in Barrett-associated esophageal adenocarcinomas and is associated with positive lymph node status
Martin Grimm, Maria Lazariotou, Stefan Kircher, Luisa Stuermer, Christoph Reiber, Andreas Höfelmayr, Stefan Gattenlöhner, Christoph Otto, Christoph T Germer, Burkhard HA von Rahden
Cellular and vaccine therapeutic approaches for gliomas
Michelle J Hickey, Colin C Malone, Kate L Erickson, Martin R Jadus, Robert M Prins, Linda M Liau, Carol A Kruse
Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance
Chun-Wei Peng, Xiu-Li Liu, Xiong Liu, Yan Li
Biotechnology entrepreneurship - where no research has gone before
Michael L Salgaller, Francesco M Marincola
Prognostic impact of clinical course-specific mRNA expression profiles in the serum of perioperative patients with esophageal cancer in the ICU: a case control study
Shunsaku Takahashi, Norimasa Miura, Tomomi Harada, ZhongZhi Wang, Xinhui Wang, Hideyuki Tsubokura, Yoshiaki Oshima, Junichi Hasegawa, Yoshimi Inagaki, Goshi Shiota
Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: Differing impact on CD8 T cell phenotype and responsiveness to restimulation
Yixin Li, Roger J Kurlander
HPV vaccine: an overview of immune response, clinical protection, and new approaches for the future
Luciano Mariani, Aldo Venuti
Exhaustive expansion: A novel technique for analyzing complex data generated by higher-order polychromatic flow cytometry experiments
Janet C Siebert, Lian Wang, Daniel P Haley, Ann Romer, Bo Zheng, Wes Munsil, Kenton W Gregory, Edwin B Walker
Detection of carcinoembryonic antigen messenger RNA in blood using quantitative real-time reverse transcriptase-polymerase chain reaction to predict recurrence of gastric adenocarcinoma
Miao-zhen Qiu, Zhuang-hua Li, Zhi-wei Zhou, Yu-hong Li, Zhi-qiang Wang, Feng-hua Wang, Peng Huang, Fahad Aziz, Dao-yuan Wang, Rui-hua Xu
Evaluation of six CTLA-4 polymorphisms in high-risk melanoma patients receiving adjuvant interferon therapy in the He13A/98 multicenter trial
Helen Gogas, Urania Dafni, Henry Koon, Maria Spyropoulou-Vlachou, Yannis Metaxas, Elizabeth Buchbinder, Eirini Pectasides, Dimosthenis Tsoutsos, Aristidis Polyzos, Alexandros Stratigos, Christos Markopoulos, Petros Panagiotou, George Fountzilas, Ourania Castana, Pantelis Skarlos, Michael B Atkins, John M Kirkwood
Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment
Giuseppe Castello, Susan Costantini, Stefania Scala
Epigenetic change in e-cardherin and COX-2 to predict chronic periodontitis
Wings TY Loo, Lijian Jin, Mary NB Cheung, Min Wang, Louis WC Chow
Quantification of newly produced B and T lymphocytes in untreated chronic lymphocytic leukemia patients
Marina Motta, Marco Chiarini, Claudia Ghidini, Cinzia Zanotti, Cinzia Lamorgese, Luigi Caimi, Giuseppe Rossi, Luisa Imberti
The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker
Rosaria Cammarota, Valentina Bertolini, Giuseppina Pennesi, Eraldo O Bucci, Ornella Gottardi, Cecilia Garlanda, Luigi Laghi, Massimo C Barberis, Fausto Sessa, Douglas M Noonan, Adriana Albini
IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease
Eva d'Hennezel, Mara Kornete, Ciriaco A Piccirillo
Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies
Giuseppina Bonanno, Annabella Procoli, Andrea Mariotti, Maria Corallo, Alessandro Perillo, Silvio Danese, Raimondo De Cristofaro, Giovanni Scambia, Sergio Rutella
High activity of sequential low dose chemo-modulating Temozolomide in combination with Fotemustine in metastatic melanoma. A feasibility study
Michele Guida, Antonio Cramarossa, Ettore Fistola, Mariangela Porcelli, Giuseppe Giudice, Katia Lubello, Giuseppe Colucci
Interleukin-13 receptor α2 DNA prime boost vaccine induces tumor immunity in murine tumor models
Hideyuki Nakashima, Toshio Fujisawa, Syed R Husain, Raj K Puri
The emerging role of insulin-like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs)
Maria A Pantaleo, Annalisa Astolfi, Margherita Nannini, Guido Biasco
Zinc in innate and adaptive tumor immunity
Erica John, Thomas C Laskow, William J Buchser, Bruce R Pitt, Per H Basse, Lisa H Butterfield, Pawel Kalinski, Michael T Lotze
Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea
Jeanne Oiticica, Luiz Carlos M Barboza-Junior, Ana Carla Batissoco, Karina Lezirovitz, Regina C Mingroni-Netto, Luciana A Haddad, Ricardo F Bento
Exploring the molecular mechanisms underlying the potentiation of exogenous growth hormone on alcohol-induced fatty liver diseases in mice
Ying Qin, Ya-ping Tian
Impact of γ-chain cytokines on EBV-specific T cell cultures
Anna Merlo, Riccardo Turrini, Cristina Trento, Paola Zanovello, Riccardo Dolcetti, Antonio Rosato
Early detection of urothelial premalignant lesions using hexaminolevulinate fluorescence cystoscopy in high risk patients
Salvatore Blanco, Marco Raber, Biagio Eugenio Leone, Luca Nespoli, Marco Grasso
LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer
Lydia Kriegl, David Horst, Jana A Reiche, Jutta Engel, Thomas Kirchner, Andreas Jung
Generalized cerebral atrophy seen on MRI in a naturally exposed animal model for creutzfeldt-jakob disease
Alexia L McKnight, Lawrence A Minkoff, Diane L Sutton, Bruce V Thomsen, Perry L Habecker, Raymond W Sweeney, Gary Smith, Constantin A Dasanu, Thomas E Ichim, Doru T Alexandrescu, Joel M Stutman
DNA polymeraseη protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy
Kai-yuan Teng, Miao-zhen Qiu, Zhuang-hua Li, Hui-yan Luo, Zhao-lei Zeng, Rong-zhen Luo, Hui-zhong Zhang, Zhi-qiang Wang, Yu-hong Li, Rui-hua Xu
Prevalence of the GJB2 IVS1+1G >A mutation in Chinese hearing loss patients with monoallelic pathogenic mutation in the coding region of GJB2
Yongyi Yuan, Fei Yu, Guojian Wang, Shasha Huang, Ruili Yu, Xin Zhang, Deliang Huang, Dongyi Han, Pu Dai
Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque
Suman Dwivedi, Dharmendra Pandey, Anna L Khandoga, Richard Brandl, Wolfgang Siess
Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures
Giuseppina Bonanno, Paola Iudicone, Andrea Mariotti, Annabella Procoli, Annino Pandolfi, Daniela Fioravanti, Maria Corallo, Alessandro Perillo, Giovanni Scambia, Luca Pierelli, Sergio Rutella
Immuno-Oncology biomarkers 2010 and beyond: Perspectives from the iSBTc/SITC biomarker task force
Lisa H Butterfield, Mary L Disis, Samir N Khleif, James M Balwit, Francesco M Marincola
Future research and therapeutic applications of human stem cells: general, regulatory, and bioethical aspects
Antonio Liras
Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity
Adrian Bot, Zhiyong Qiu, Raymond Wong, Mihail Obrocea, Kent A Smith
Prevention of hyperglycemia-induced myocardial apoptosis by gene silencing of Toll-like receptor-4
Yuwei Zhang, Tianqing Peng, Huaqing Zhu, Xiufen Zheng, Xusheng Zhang, Nan Jiang, Xiaoshu Cheng, Xiaoyan Lai, Aminah Shunnar, Manpreet Singh, Neil Riordan, Vladimir Bogin, Nanwei Tong, Wei-Ping Min
Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences
Doron Amit, Abraham Hochberg
Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer
Sara Simonetti, Miguel Angel Molina, Cristina Queralt, Itziar de Aguirre, Clara Mayo, Jordi Bertran-Alamillo, José Javier Sanchez, Jose Luis Gonzalez-Larriba, Ulpiano Jimenez, Dolores Isla, Teresa Moran, Santiago Viteri, Carlos Camps, Rosario Garcia-Campelo, Bartomeu Massuti, Susana Benlloch, Santiago Ramon y Cajal, Miquel Taron, Rafael Rosell
Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference
Qin Xu, Xiuming Liu, Wantao Chen, Zhiyuan Zhang
Immunoreactivity of anti-gelsolin antibodies: implications for biomarker validation
Nicole Haverland, Gwënaël Pottiez, Jayme Wiederin, Pawel Ciborowski
Endotoxin and CD14 in the progression of biliary atresia
Ming-Huei Chou, Jiin-Haur Chuang, Hock-Liew Eng, Ching-Mei Chen, Chiou-Huey Wang, Chao-Long Chen, Tsun-Mei Lin
The effect of acyclovir on the tubular secretion of creatinine in vitro
Patrina Gunness, Katarina Aleksa, Gideon Koren
Morphologic complexity of epithelial architecture for predicting invasive breast cancer survival
Mauro Tambasco, Misha Eliasziw, Anthony M Magliocco