Ausgabe 1/2011
Inhalt (223 Artikel)
Optical Nerve Detection by Diffuse Reflectance Spectroscopy for Feedback Controlled Oral and Maxillofacial Laser Surgery
Florian Stelzle, Azhar Zam, Werner Adler, Katja Tangermann-Gerk, Alexandre Douplik, Emeka Nkenke, Michael Schmidt
The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil
María Sánchez-Aragó, José M Cuezva
CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells
Claudia Rubie, Vilma O Frick, Pirus Ghadjar, Mathias Wagner, Christoph Justinger, Sabrina K Faust, Benjamin Vicinus, Stefan Gräber, Otto Kollmar, Martin K Schilling
Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study
Brunna E Alves, Silmara AL Montalvao, Francisco JP Aranha, Irene Lorand-Metze, Carmino A De Souza, Joyce M Annichino-Bizzacchi, Erich V De Paula
Increase of plasma IL-9 and decrease of plasma IL-5, IL-7, and IFN-γ in patients with chronic heart failure
Claudia Cappuzzello, Luca Di Vito, Roberta Melchionna, Guido Melillo, Lorena Silvestri, Eleonora Cesareo, Filippo Crea, Giovanna Liuzzo, Antonio Facchiano, Maurizio C Capogrossi, Monica Napolitano
MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells
Kayoko Matsushima, Hajime Isomoto, Naoyuki Yamaguchi, Naoki Inoue, Haruhisa Machida, Toshiyuki Nakayama, Tomayoshi Hayashi, Masaki Kunizaki, Shigekazu Hidaka, Takeshi Nagayasu, Masahiro Nakashima, Kenta Ujifuku, Norisato Mitsutake, Akira Ohtsuru, Shunichi Yamashita, Manav Korpal, Yibin Kang, Philip A Gregory, Gregory J Goodall, Shigeru Kohno, Kazuhiko Nakao
High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area
Tai-Jan Chiu, Chang-Han Chen, Chih-Yen Chien, Shau-Hsuan Li, Hsin-Ting Tsai, Yi-Ju Chen
Future perspectives in melanoma research. Meeting report from the "Melanoma Research: a bridge Naples-USA. Naples, December 6 th -7 th 2010"
Paolo A Ascierto, Eleonora De Maio, Stefano Bertuzzi, Giuseppe Palmieri, Ruth Halaban, Mary Hendrix, Mohamed Kashani-sabet, Soldano Ferrone, Ena Wang, Alistair Cochran, Licia Rivoltini, Peter P Lee, Bernard A Fox, John M Kirkwood, Claudio Dansky Ullmann, Frederic F Lehmann, Mario Sznol, Douglas J Schwartzentruber, Michele Maio, Keith Flaherty, Jerome Galon, Antoni Ribas, James Yang, David F Stroncek, Nicola Mozzillo, Franco M Marincola
In vitro migration of cytotoxic T lymphocyte derived from a colon carcinoma patient is dependent on CCL2 and CCR2
Klara Berencsi, Pyapalli Rani, Tianqian Zhang, Laura Gross, Michael Mastrangelo, Neal J Meropol, Dorothee Herlyn, Rajasekharan Somasundaram
Tumor escape and progression of HER-2/neu negative breast cancer under immune pressure
Maciej Kmieciak, Kyle K Payne, Michael O Idowu, Margaret M Grimes, Laura Graham, Maria-Libera Ascierto, Ena Wang, Xiang-Yang Wang, Harry D Bear, Masoud H Manjili
Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy
Wenxue Ma, Trevor Smith, Vladimir Bogin, Yu Zhang, Cengiz Ozkan, Mihri Ozkan, Melanie Hayden, Stephanie Schroter, Ewa Carrier, Davorka Messmer, Vipin Kumar, Boris Minev
Insertion of the human sodium iodide symporter to facilitate deep tissue imaging does not alter oncolytic or replication capability of a novel vaccinia virus
Dana Haddad, Nanhai G Chen, Qian Zhang, Chun-Hao Chen, Yong A Yu, Lorena Gonzalez, Susanne G Carpenter, Joshua Carson, Joyce Au, Arjun Mittra, Mithat Gonen, Pat B Zanzonico, Yuman Fong, Aladar A Szalay
Rational design of HIV vaccines and microbicides: report of the EUROPRISE network annual conference 2010
Sarah Brinckmann, Kelly da Costa, Marit J van Gils, David Hallengärd, Katja Klein, Luisa Madeira, Lara Mainetti, Paolo Palma, Katharina Raue, David Reinhart, Marc Reudelsterz, Nicolas Ruffin, Janna Seifried, Katrein Schäfer, Enas Sheik-Khalil, Annette Sköld, Hannes Uchtenhagen, Nicolas Vabret, Serena Ziglio, Gabriella Scarlatti, Robin Shattock, Britta Wahren, Frances Gotch
15 kDa Granulysin versus GM-CSF for monocytes differentiation: analogies and differences at the transcriptome level
Luciano Castiello, David F Stroncek, Michael W Finn, Ena Wang, Francesco M Marincola, Carol Clayberger, Alan M Krensky, Marianna Sabatino
Elevated expression of CDK4 in lung cancer
Aibing Wu, Bin Wu, Jinsong Guo, Weiren Luo, Dong Wu, Huiling Yang, Yan Zhen, Xiaoli Yu, Hao Wang, Ying Zhou, Zhen Liu, Weiyi Fang, Zhixiong Yang
Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma
Yu Xu, Jinxuan Hou, Zhengchun Liu, Haijun Yu, Wenjie Sun, Jie Xiong, Zhengkai Liao, Fuxiang Zhou, Conghua Xie, Yunfeng Zhou
Histone modification enhances the effectiveness of IL-13 receptor targeted immunotoxin in murine models of human pancreatic cancer
Toshio Fujisawa, Bharat H Joshi, Raj K Puri
Cancer stem cell subsets and their relationships
Hai-Guang Liu, Chong Chen, Han Yang, Yi-Fei Pan, Xiao-Hua Zhang
Differentiation associated regulation of microRNA expression in vivo in human CD8+ T cell subsets
Bruno Salaun, Takuya Yamamoto, Bassam Badran, Yasuko Tsunetsugu-Yokota, Antoine Roux, Lukas Baitsch, Redouane Rouas, Hussein Fayyad-Kazan, Petra Baumgaertner, Estelle Devevre, Anirudh Ramesh, Marion Braun, Daniel Speiser, Brigitte Autran, Philippe Martiat, Victor Appay, Pedro Romero
Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival of gastric cancer with peritoneal carcinomatosis: evidence from an experimental study
Li Tang, Lie-Jun Mei, Xiao-Jun Yang, Chao-Qun Huang, Yun-Feng Zhou, Yutaka Yonemura, Yan Li
Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs
Tian Sheng Chen, Fatih Arslan, Yijun Yin, Soon Sim Tan, Ruenn Chai Lai, Andre Boon Hwa Choo, Jayanthi Padmanabhan, Chuen Neng Lee, Dominique PV de Kleijn, Sai Kiang Lim
Detection and characterization of translational research in cancer and cardiovascular medicine
David S Jones, Alberto Cambrosio, Andrei Mogoutov
Neopterin production and tryptophan degradation during 24-months therapy with interferon beta-1a in multiple sclerosis patients
Valentina Durastanti, Alessandra Lugaresi, Placido Bramanti, Mariapia Amato, Paolo Bellantonio, Giovanna De Luca, Orietta Picconi, Roberta Fantozzi, Laura Locatelli, Annalisa Solda', Edoardo Sessa, Rocco Totaro, Silvia Marino, Valentina Zipoli, Marino Zorzon, Enrico Millefiorini
A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases
Chong Xie, Hyun J Kim, Jonathan G Haw, Anusha Kalbasi, Brian K Gardner, Gang Li, Jianyu Rao, David Chia, Monty Liong, Rubio R Punzalan, Leonard S Marks, Allan J Pantuck, Alexandre de la Taille, Guomin Wang, Hideki Mukouyama, Gang Zeng
Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes
Yi Li, Gang Ren, Yan-Xiang Wang, Wei-Jia Kong, Peng Yang, Yue-Ming Wang, Ying-Hong Li, Hong Yi, Zhuo-Rong Li, Dan-Qing Song, Jian-Dong Jiang
Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma
Zhizhong Xu, Guobo Shen, Xiangying Xia, Xinyu Zhao, Peng Zhang, Huanhuan Wu, Qingfa Guo, Zhiyong Qian, Yuquan Wei, Shufang Liang
High throughput RNAi assay optimization using adherent cell cytometry
Christoph S Nabzdyk, Maggie Chun, Leena Pradhan, Frank W LoGerfo
Pro-apoptotic activity of α-bisabolol in preclinical models of primary human acute leukemia cells
Elisabetta Cavalieri, Antonella Rigo, Massimiliano Bonifacio, Alessandra Carcereri de Prati, Emanuele Guardalben, Christian Bergamini, Romana Fato, Giovanni Pizzolo, Hisanori Suzuki, Fabrizio Vinante
Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction
Yen-Ta Chen, Cheuk-Kwan Sun, Yu-Chun Lin, Li-Teh Chang, Yung-Lung Chen, Tzu-Hsien Tsai, Sheng-Ying Chung, Sarah Chua, Ying-Hsien Kao, Chia-Hung Yen, Pei-Lin Shao, Kuan-Cheng Chang, Steve Leu, Hon-Kan Yip
Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety
Akio Ido, Akihiro Moriuchi, Masatsugu Numata, Toshinori Murayama, Satoshi Teramukai, Hiroyuki Marusawa, Naohisa Yamaji, Hitoshi Setoyama, Il-Deok Kim, Tsutomu Chiba, Shuji Higuchi, Masayuki Yokode, Masanori Fukushima, Akira Shimizu, Hirohito Tsubouchi
Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18
Clarisa Salado, Elvira Olaso, Natalia Gallot, Maria Valcarcel, Eider Egilegor, Lorea Mendoza, Fernando Vidal-Vanaclocha
Therapeutic effects of pyrrolidine dithiocarbamate on acute lung injury in rabbits
Meitang Wang, Tao Liu, Dian Wang, Yonghua Zheng, Xiangdong Wang, Jian He
Human umbilical cord blood-derived mononuclear cell transplantation: case series of 30 subjects with Hereditary Ataxia
Wan-Zhang Yang, Yun Zhang, Fang Wu, Min Zhang, SC Cho, Chun-Zhen Li, Shao-Hui Li, Guo-Jian Shu, You-Xiang Sheng, Ning Zhao, Ying Tang, Shu Jiang, Shan Jiang, Matthew Gandjian, Thomas E Ichim, Xiang Hu
Prostate transglutaminase (TGase-4) antagonizes the anti-tumour action of MDA-7/IL-24 in prostate cancer
Richard J Ablin, Howard G Kynaston, Malcolm D Mason, Wen G Jiang
Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke
Raquel Rodríguez-González, Tomás Sobrino, Manuel Rodríguez-Yáñez, Mónica Millán, David Brea, Elena Miranda, Octavio Moldes, Juan Pérez, David A Lomas, Rogelio Leira, Antoni Dávalos, José Castillo
Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients
Diana L Simons, Gerald Lee, John M Kirkwood, Peter P Lee
Create a translational medicine knowledge repository - Research downsizing, mergers and increased outsourcing have reduced the depth of in-house translational medicine expertise and institutional memory at many pharmaceutical and biotech companies: how will they avoid relearning old lessons?
Bruce H Littman, Francesco M Marincola
Review of the 25th annual scientific meeting of the International Society for Biological Therapy of Cancer
James M Balwit, Pawel Kalinski, Vernon K Sondak, Pierre G Coulie, Elizabeth M Jaffee, Thomas F Gajewski, Francesco M Marincola
Concomitant detection of IFNα signature and activated monocyte/dendritic cell precursors in the peripheral blood of IFNα-treated subjects at early times after repeated local cytokine treatments
Eleonora Aricò, Luciano Castiello, Francesca Urbani, Paola Rizza, Monica C Panelli, Ena Wang, Francesco M Marincola, Filippo Belardelli
Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274
Jinxuan Hou, Jixin Dong, Lijun Sun, Liying Geng, Jing Wang, Jialin Zheng, Yan Li, Julia Bridge, Steven H Hinrichs, Shi-Jian Ding
Improvement of cardiac contractile function by peptide-based inhibition of NF-κB in the utrophin/dystrophin-deficient murine model of muscular dystrophy
Dawn A Delfín, Ying Xu, Jennifer M Peterson, Denis C Guttridge, Jill A Rafael-Fortney, Paul ML Janssen
SULFs in human neoplasia: implication as progression and prognosis factors
Caroline Bret, Jérôme Moreaux, Jean-François Schved, Dirk Hose, Bernard Klein
Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cells
Duo-Rong Xu, Shan Huang, Zi-Jie Long, Jia-Jie Chen, Zheng-Zhi Zou, Juan Li, Dong-Jun Lin, Quentin Liu
The role of mutational analysis of KIT and PDGFRA in gastrointestinal stromal tumors in a clinical setting
Alessandra Maleddu, Maria A Pantaleo, Margherita Nannini, Guido Biasco
Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations
Franziska Niehr, Erika von Euw, Narsis Attar, Deliang Guo, Doug Matsunaga, Hooman Sazegar, Charles Ng, John A Glaspy, Juan A Recio, Roger S Lo, Paul S Mischel, Begonya Comin-Anduix, Antoni Ribas
Plasma proteome changes in cardiovascular disease patients: novel isoforms of apolipoprotein A1
Pavel Májek, Zuzana Reicheltová, Jiří Suttnar, Martin Malý, Milan Oravec, Klára Pečánková, Jan E Dyr
An NIH intramural percubator as a model of academic-industry partnerships: from the beginning of life through the valley of death
Michael R Emmert-Buck
Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells
Jia Rao, Duo-Rong Xu, Fei-Meng Zheng, Zi-Jie Long, Sheng-Shan Huang, Xing Wu, Wei-Hua Zhou, Ren-Wei Huang, Quentin Liu
Time-dependent cytotoxic drugs selectively cooperate with IL-18 for cancer chemo-immunotherapy
Ioannis Alagkiozidis, Andrea Facciabene, Marinos Tsiatas, Carmine Carpenito, Fabian Benencia, Sarah Adams, Zdenka Jonak, Carl H June, Daniel J Powell Jr, George Coukos
Understanding tumor heterogeneity as functional compartments - superorganisms revisited
Thomas GP Grunewald, Saskia M Herbst, Jürgen Heinze, Stefan Burdach
Body fluid derived exosomes as a novel template for clinical diagnostics
Sascha Keller, Johannes Ridinger, Anne-Kathleen Rupp, Johannes WG Janssen, Peter Altevogt
Negative enrichment by immunomagnetic nanobeads for unbiased characterization of circulating tumor cells from peripheral blood of cancer patients
Zhian Liu, Alberto Fusi, Eva Klopocki, Alexander Schmittel, Ingeborg Tinhofer, Anika Nonnenmacher, Ulrich Keilholz
Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model
Linda Petrone, Maria G Ammendolia, Armando Cesolini, Stefano Caimi, Fabiana Superti, Colomba Giorgi, Paola Di Bonito
The combined transduction of copper, zinc-superoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury
Guang-Qing Huang, Jia-Ning Wang, Jun-Ming Tang, Lei Zhang, Fei Zheng, Jian-Ye Yang, Ling-Yun Guo, Xia Kong, Yong-Zhang Huang, Yong Liu, Shi-You Chen
A large, consistent plasma proteomics data set from prospectively collected breast cancer patient and healthy volunteer samples
Catherine P Riley, Xiang Zhang, Harikrishna Nakshatri, Bryan Schneider, Fred E Regnier, Jiri Adamec, Charles Buck
Immunological abnormalities as potential biomarkers in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Ekua W Brenu, Mieke L van Driel, Don R Staines, Kevin J Ashton, Sandra B Ramos, James Keane, Nancy G Klimas, Sonya M Marshall-Gradisnik
Rapid label-free identification of mixed bacterial infections by surface plasmon resonance
Jue Wang, Yang Luo, Bo Zhang, Ming Chen, Junfu Huang, Kejun Zhang, Weiyin Gao, Weiling Fu, Tianlun Jiang, Pu Liao
Methylation levels of the "long interspersed nucleotide element-1" repetitive sequences predict survival of melanoma patients
Luca Sigalotti, Elisabetta Fratta, Ettore Bidoli, Alessia Covre, Giulia Parisi, Francesca Colizzi, Sandra Coral, Samuele Massarut, John M Kirkwood, Michele Maio
Induction of Th1Immune responses following laser ablation in a murine model of colorectal liver metastases
Wen Xu Lin, Theodora Fifis, Caterina Malcontenti-Wilson, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Linh Nguyen, Christopher Christophi
Codon usage in vertebrates is associated with a low risk of acquiring nonsense mutations
Pirmin Schmid, Willy A Flegel
Value of large scale expansion of tumor infiltrating lymphocytes in a compartmentalised gas-permeable bag: interests for adoptive immunotherapy
Thomas Zuliani, Julien David, Sylvain Bercegeay, Marie-Christine Pandolfino, Isabelle Rodde-Astier, Amir Khammari, Cécile Coissac, Bruno Delorme, Soraya Saïagh, Brigitte Dréno
Ozone acting on human blood yields a hormetic dose-response relationship
Velio A Bocci, Iacopo Zanardi, Valter Travagli
A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment
Chi-Jung Huang, Shung-Haur Yang, Shih-Ming Huang, Chih-Ming Lin, Chih-Cheng Chien, Yan-Chu Chen, Chia-Long Lee, Hao-Han Wu, Chun-Chao Chang
No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients
Qing Xia, Xiao-Jun Wu, Qiang Zhou, Jing-Zeng, Jing-Hui Hou, Zhi-Zhong Pan, Xiao-Shi Zhang
Functional characterization of human Cd33+ And Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines
Melissa G Lechner, Carolina Megiel, Sarah M Russell, Brigid Bingham, Nicholas Arger, Tammy Woo, Alan L Epstein
Buffy coat specimens remain viable as a DNA source for highly multiplexed genome-wide genetic tests after long term storage
Josyf C Mychaleckyj, Emily A Farber, Jessica Chmielewski, Jamie Artale, Laney S Light, Donald W Bowden, Xuanlin Hou, Santica M Marcovina
Trauma is danger
Paul F Hwang, Nancy Porterfield, Dylan Pannell, Thomas A Davis, Eric A Elster
The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance
Fei Xie, Lin Ye, Jinfeng Chen, Nan Wu, Zhiqian Zhang, Yue Yang, Lijian Zhang, Wen G Jiang
Protein kinase CK2α is overexpressed in colorectal cancer and modulates cell proliferation and invasion via regulating EMT-related genes
Jinjin Zou, Hesan Luo, Qin Zeng, Zhongyi Dong, Dehua Wu, Li Liu
Comparative study of clinical grade human tolerogenic dendritic cells
M Naranjo-Gómez, D Raïch-Regué, C Oñate, L Grau-López, C Ramo-Tello, R Pujol-Borrell, E Martínez-Cáceres, Francesc E Borràs
CD4saurus Rex &HIVelociraptor vs. development of clinically useful immunological markers: a Jurassic tale of frozen evolution
Andrea De Maria, Andrea Cossarizza
Peritoneal carcinomatosis from ovarian cancer: chemosensitivity test and tissue markers as predictors of response to chemotherapy
Chiara Arienti, Anna Tesei, Giorgio Maria Verdecchia, Massimo Framarini, Salvatore Virzì, Antonio Grassi, Emanuela Scarpi, Livia Turci, Rosella Silvestrini, Dino Amadori, Wainer Zoli
Spectratyping analysis of the islet-reactive T cell repertoire in diabetic NOD Igμnull mice after polyclonal B cell reconstitution
Allen M Vong, Nazila Daneshjou, Patricia Y Norori, Huiming Sheng, Todd A Braciak, Eli E Sercarz, Claudia Raja Gabaglia
Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients
Thomas K Kilvaer, Andrej Valkov, Sveinung W Sorbye, Eivind Smeland, Roy M Bremnes, Lill-Tove Busund, Tom Donnem
Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication
Chiara Orlandi, Greta Forlani, Giovanna Tosi, Roberto S Accolla
Phosphoproteomic analysis of apoptotic hematopoietic stem cells from hemoglobin E/β-thalassemia
Saranyoo Ponnikorn, Tasanee Panichakul, Kitima Sresanga, Chokdee Wongborisuth, Sittiruk Roytrakul, Suradej Hongeng, Sumalee Tungpradabkul
Transcription and translation of human F11R gene are required for an initial step of atherogenesis induced by inflammatory cytokines
Bani M Azari, Jonathan D Marmur, Moro O Salifu, Yigal H Ehrlich, Elizabeth Kornecki, Anna Babinska
Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFβ1-signaling and increased Galectin-3 expression: A histological study on biopsies
Falk Wehrhan, Peter Hyckel, Arndt Guentsch, Emeka Nkenke, Phillip Stockmann, Karl A Schlegel, Friedrich W Neukam, Kerstin Amann
Periostin: a promising target of therapeutical intervention for prostate cancer
Chuanyu Sun, Xiaojun Zhao, Ke Xu, Jian Gong, Weiwei Liu, Weihong Ding, Yuancheng Gou, Guowei Xia, Qiang Ding
Effects of transplantation with bone marrow-derived mesenchymal stem cells modified by Survivin on experimental stroke in rats
Nan Liu, Yixian Zhang, Lin Fan, Mingzhou Yuan, Houwei Du, Ronghua Cheng, Deshan Liu, Feifei Lin
Multiplex Zymography Captures Stage-specific Activity Profiles of Cathepsins K, L, and S in Human Breast, Lung, and Cervical Cancer
Binbin Chen, Manu O Platt
High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916
Christopher Moy, Catherine A Oleykowski, Ramona Plant, Joel Greshock, Junping Jing, Kurtis Bachman, Mary Ann Hardwicke, Richard Wooster, Yan Degenhardt
Serum cytokine profiles in healthy young and elderly population assessed using multiplexed bead-based immunoassays
Hyun Ok Kim, Han-Soo Kim, Jong-Chan Youn, Eui-Cheol Shin, Sungha Park
Aurora Kinase A expression is associated with lung cancer histological-subtypes and with tumor de-differentiation
Marco Lo Iacono, Valentina Monica, Silvia Saviozzi, Paolo Ceppi, Enrico Bracco, Mauro Papotti, Giorgio V Scagliotti
A critical assessment for the value of markers to gate-out undesired events in HLA-peptide multimer staining protocols
Sebastian Attig, Leah Price, Sylvia Janetzki, Michael Kalos, Michael Pride, Lisa McNeil, Tim Clay, Jianda Yuan, Kunle Odunsi, Axel Hoos, Pedro Romero, Cedrik M Britten
Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats
Inma Castilla-Cortázar, María García-Fernández, Gloria Delgado, Juan E Puche, Inma Sierra, Rima Barhoum, Salvador González-Barón
Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine
Joanna D Holbrook, Joel S Parker, Kathleen T Gallagher, Wendy S Halsey, Ashley M Hughes, Victor J Weigman, Peter F Lebowitz, Rakesh Kumar
Complement component C5a Promotes Expression of IL-22 and IL-17 from Human T cells and its Implication in Age-related Macular Degeneration
Baoying Liu, Lai Wei, Catherine Meyerle, Jingsheng Tuo, H Nida Sen, Zhiyu Li, Sagarika Chakrabarty, Elvira Agron, Chi-Chao Chan, Michael L Klein, Emily Chew, Frederick Ferris, Robert B Nussenblatt
Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model
Cheuk-Kwan Sun, Chia-Hung Yen, Yu-Chun Lin, Tzu-Hsien Tsai, Li-Teh Chang, Ying-Hsien Kao, Sarah Chua, Morgan Fu, Sheung-Fat Ko, Steve Leu, Hon-Kan Yip
Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: An analysis of 215 cases from the Malmö Diet and Cancer Study
Liv Jonsson, Julia Bergman, Björn Nodin, Jonas Manjer, Fredrik Pontén, Mathias Uhlén, Karin Jirström
Combination therapy: the next opportunity and challenge of medicine
Paolo A Ascierto, Francesco M Marincola
Cytotoxic T lymphocyte responses against melanocytes and melanoma
Gwendolen Y Chang, Holbrook E Kohrt, Tor B Stuge, Erich J Schwartz, Jeffrey S Weber, Peter P Lee
Summit on cell therapy for cancer: The importance of the interaction of multiple disciplines to advance clinical therapy
Cornelis JM Melief, John J O'Shea, David F Stroncek
Introducing the neurosciences section of the journal of translational medicine
Luis F Alguacil
Biobanking after robotic-assisted radical prostatectomy: a quality assessment of providing prostate tissue for RNA studies
Harveer Dev, David Rickman, Prasanna Sooriakumaran, Abhishek Srivastava, Sonal Grover, Robert Leung, Robert Kim, Naoki Kitabayashi, Raquel Esqueva, Kyung Park, Jessica Padilla, Mark Rubin, Ashutosh Tewari
Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats
Maria Garcia-Fernandez, Inma Sierra, Juan E Puche, Lucia Guerra, Inma Castilla-Cortazar
Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma
Mikiko Takikita, Ran Xie, Joon-Yong Chung, Hanbyoul Cho, Kris Ylaya, Seung-Mo Hong, Christopher A Moskaluk, Stephen M Hewitt
The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease
Hayk Davtyan, Anahit Ghochikyan, Richard Cadagan, Dmitriy Zamarin, Irina Petrushina, Nina Movsesyan, Luis Martinez-Sobrido, Randy A Albrecht, Adolfo García-Sastre, Michael G Agadjanyan
SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice
Jin-Hong Shin, Brian Bostick, Yongping Yue, Roger Hajjar, Dongsheng Duan
Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib
Charles S Harmon, Samuel E DePrimo, Eric Raymond, Ann-Lii Cheng, Eveline Boucher, Jean-Yves Douillard, Ho Y Lim, Jun S Kim, Maria José Lechuga, Silvana Lanzalone, Xun Lin, Sandrine Faivre
Electroporation increases antitumoral efficacy of the bcl-2 antisense G3139 and chemotherapy in a human melanoma xenograft
Enrico P Spugnini, Annamaria Biroccio, Roberta De Mori, Marco Scarsella, Carmen D'Angelo, Alfonso Baldi, Carlo Leonetti
Science that "knows" and science that "asks"
Pierre R Smeesters, Marie Deghorain, Andrew C Steer
Anti-inflammatory effects of nicotine in obesity and ulcerative colitis
Shaheen E Lakhan, Annette Kirchgessner
Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytes
Qunrui Ye, Maria Loisiou, Bruce L Levine, Megan M Suhoski, James L Riley, Carl H June, George Coukos, Daniel J Powell Jr
Increased human defensine levels hint at an inflammatory etiology of bisphosphonate-associated osteonecrosis of the jaw: An immunohistological study
Philipp Stockmann, Falk Wehrhan, Stephan Schwarz-Furlan, Florian Stelzle, Susanne Trabert, Friedrich W Neukam, Emeka Nkenke
Clinical translation section: accelerating the pace from bench to bedside
Lana E Kandalaft, George Coukos
Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation--a phase I study (MISOT-I)
Felix C Popp, Barbara Fillenberg, Elke Eggenhofer, Philipp Renner, Johannes Dillmann, Volker Benseler, Andreas A Schnitzbauer, James Hutchinson, Robert Deans, Deborah Ladenheim, Cheryl A Graveen, Florian Zeman, Michael Koller, Martin J Hoogduijn, Edward K Geissler, Hans J Schlitt, Marc H Dahlke
Glycyrrhizin as antiviral agent against Hepatitis C Virus
Usman A Ashfaq, Muhammad S Masoud, Zafar Nawaz, Sheikh Riazuddin
Fuzzy obesity index (MAFOI) for obesity evaluation and bariatric surgery indication
Susana Abe Miyahira, João Luiz Moreira Coutinho de Azevedo, Ernesto Araújo
Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas
Christoph Bergmann, Hagen S Bachmann, Agnes Bankfalvi, Ramin Lotfi, Carolin Pütter, Clarissa A Wild, Patrick J Schuler, Jens Greve, Thomas K Hoffmann, Stephan Lang, André Scherag, Götz F Lehnerdt
Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer
Natasja K van den Engel, Dominik Rüttinger, Margareta Rusan, Robert Kammerer, Wolfgang Zimmermann, Rudolf A Hatz, Hauke Winter
An intronic SNP in the thyroid hormone receptor β gene is associated with pituitary cell-specific over-expression of a mutant thyroid hormone receptor β2 (R338W) in the index case of pituitary-selective resistance to thyroid hormone
Anna Teresa Alberobello, Valentina Congedo, Hong Liu, Craig Cochran, Monica C Skarulis, Douglas Forrest, Francesco S Celi
Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer
Aymen A Elfiky, Saadia A Aziz, Patricia J Conrad, Summar Siddiqui, Wolfgang Hackl, Michel Maira, Camp L Robert, Harriet M Kluger
CGB and GNRH1 expression analysis as a method of tumor cells metastatic spread detection in patients with gynecological malignances
Mirosław Andrusiewicz, Anna Szczerba, Maria Wołuń-Cholewa, Wojciech Warchoł, Ewa Nowak-Markwitz, Emilia Gąsiorowska, Krystyna Adamska, Anna Jankowska
Generation of high-titer viral preparations by concentration using successive rounds of ultracentrifugation
Christine V Ichim, Richard A Wells
An immunologic portrait of cancer
Maria Libera Ascierto, Valeria De Giorgi, Qiuzhen Liu, Davide Bedognetti, Tara L Spivey, Daniela Murtas, Lorenzo Uccellini, Ben D Ayotte, David F Stroncek, Lotfi Chouchane, Masoud H Manjili, Ena Wang, Francesco M Marincola
Generating HPV specific T helper cells for the treatment of HPV induced malignancies using TCR gene transfer
Kirsten BJ Scholten, Annelies W Turksma, Janneke J Ruizendaal, Muriel van den Hende, Sjoerd H van der Burg, Mirjam HM Heemskerk, Chris JLM Meijer, Erik Hooijberg
Cancer vaccines at an inflexion point: what next?
Adrian Bot, Mihail Obrocea, Francesco M Marincola
Liver-spleen axis, insulin-like growth factor-(IGF)-I axis and fat mass in overweight/obese females
Silvia Savastano, Carolina Di Somma, Genoveffa Pizza, Annalba De Rosa, Valeria Nedi, Annalisa Rossi, Francesco Orio, Gaetano Lombardi, Annamaria Colao, Giovanni Tarantino
Combination of cyclosporine and erythropoietin improves brain infarct size and neurological function in rats after ischemic stroke
Chun-Man Yuen, Cheuk-Kwan Sun, Yu-Chun Lin, Li-Teh Chang, Ying-Hsien Kao, Chia-Hung Yen, Yung-Lung Chen, Tzu-Hsien Tsai, Sarah Chua, Pei-Lin Shao, Steve Leu, Hon-Kan Yip
A whole blood monokine-based reporter assay provides a sensitive and robust measurement of the antigen-specific T cell response
Aron Chakera, Sophia C Bennett, Richard J Cornall
Circulating CD133+CD34+ progenitor cells inversely correlate with soluble ICAM-1 in early ischemic stroke patients
Tanya Bogoslovsky, Maria Spatz, Aneeka Chaudhry, Dragan Maric, Marie Luby, Joseph Frank, Steven Warach
Characteristics of Chinese patients with cough in primary care centre
Qunying Hong, Chunxue Bai, Xiangdong Wang
Myocardial production and release of MCP-1 and SDF-1 following myocardial infarction: differences between mice and man
Andrew J Boyle, Yerem Yeghiazarians, Henry Shih, Joy Hwang, Jianqin Ye, Rich Sievers, Daiwei Zheng, Jath Palasubramaniam, Dharshan Palasubramaniam, Connie Karschimkus, Robert Whitbourn, Alicia Jenkins, Andrew M Wilson
Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission
Barbara Beck, Daniela Dörfel, Felix S Lichtenegger, Christiane Geiger, Lysann Lindner, Martina Merk, Dolores J Schendel, Marion Subklewe
Electrochemotherapy with cisplatin enhances local control after surgical ablation of fibrosarcoma in cats: an approach to improve the therapeutic index of highly toxic chemotherapy drugs
Enrico P Spugnini, Sylvie M Renaud, Sabrina Buglioni, Francesca Carocci, Emanuele Dragonetti, Raffaele Murace, Pierluigi Cardelli, Bruno Vincenzi, Alfonso Baldi, Gennaro Citro
Cancer/Testis antigens as potential predictors of biochemical recurrence of prostate cancer following radical prostatectomy
Takumi Shiraishi, Naoki Terada, Yu Zeng, Takahito Suyama, Jun Luo, Bruce Trock, Prakash Kulkarni, Robert H Getzenberg
Promoter methylation and downregulation of SLC22A18 are associated with the development and progression of human glioma
Sheng-Hua Chu, Dong-Fu Feng, Yan-Bin Ma, Hong Zhang, Zhi-An Zhu, Zhi-Qiang Li, Pu-Cha Jiang
An novel role of sphingosine kinase-1 (SPHK1) in the invasion and metastasis of esophageal carcinoma
Jian Pan, Yan-Fang Tao, Zhuan Zhou, Bang-rong Cao, Shui-Yan Wu, Yan-Lan Zhang, Shao-Yan Hu, Wen-Li Zhao, Jian Wang, Guo-Liang Lou, Zhen Li, Xing Feng, Jian Ni
Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
María Valcárcel, Lorea Mendoza, José-Julio Hernández, Teresa Carrascal, Clarisa Salado, Olatz Crende, Fernando Vidal-Vanaclocha
Genetic mutations in non-syndromic deafness patients of uyghur and han chinese ethnicities in xinjiang, China: a comparative study
Yu Chen, Mayila Tudi, Jie Sun, Chao He, Hong-li Lu, Qing Shang, Di Jiang, Pilidong Kuyaxi, Bin Hu, Hua Zhang
SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: Online resources and useful tools - a compass in the land of biomarker discovery
Davide Bedognetti, James M Balwit, Ena Wang, Mary L Disis, Cedrik M Britten, Lucia G Delogu, Sara Tomei, Bernard A Fox, Thomas F Gajewski, Francesco M Marincola, Lisa H Butterfield
MicroRNA-134 as a potential plasma biomarker for the diagnosis of acute pulmonary embolism
Junjie Xiao, Zhi-Cheng Jing, Patrick T Ellinor, Dandan Liang, Hong Zhang, Ying Liu, Xiaoli Chen, Lei Pan, Robert Lyon, Yi Liu, Lu-Ying Peng, Xingqun Liang, Yunfu Sun, Laurentiu M Popescu, Gianluigi Condorelli, Yi-Han Chen
c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells
Ting Sun, DanDan Li, LinLin Wang, LiangPing Xia, JianGuo Ma, Zhong Guan, GongKan Feng, XiaoFeng Zhu
The HIV-1 gp120/V3 modifies the response of uninfected CD4 T cells to antigen presentation: mapping of the specific transcriptional signature
Antigone K Morou, Filippos Porichis, Elias Krambovitis, George Sourvinos, Demetrios A Spandidos, Alexandros Zafiropoulos
Elevated levels of circulating IL-7 and IL-15 in patients with early stage prostate cancer
Chantal Mengus, Clémentine Le Magnen, Emanuele Trella, Kawa Yousef, Lukas Bubendorf, Maurizio Provenzano, Alexander Bachmann, Michael Heberer, Giulio C Spagnoli, Stephen Wyler
The role of amputation as an outcome measure in cellular therapy for critical limb ischemia: implications for clinical trial design
Eric Benoit, Thomas F O'Donnell Jr, Mark D Iafrati, Enrico Asher, Dennis F Bandyk, John W Hallett, Alan B Lumsden, Gregory J Pearl, Sean P Roddy, Krishnaswami Vijayaraghavan, Amit N Patel
Proteomic detection of a large amount of SCGFα in the stroma of GISTs after imatinib therapy
Luca Da Riva, Fabio Bozzi, Piera Mondellini, Francesca Miccichè, Elena Fumagalli, Elena Vaghi, Eva Tarantino, Veronica Huber, Alessandro Gronchi, Elena Tamborini, Marco A Pierotti, Silvana Pilotti, Italia Bongarzone
Replication efficiency of oncolytic vaccinia virus in cell cultures prognosticates the virulence and antitumor efficacy in mice
Nanhai G Chen, Yong A Yu, Qian Zhang, Aladar A Szalay
Identification of MACC1 as a novel prognostic marker in hepatocellular carcinoma
Jiliang Qiu, Pinzhu Huang, Qian Liu, Jian Hong, Binkui Li, Canliang Lu, Li Wang, Jianping Wang, Yunfei Yuan
Distinct signatures of the immune responses in low risk versus high risk neuroblastoma
Madhu Gowda, Kamar Godder, Maciej Kmieciak, Andrea Worschech, Maria-Libera Ascierto, Ena Wang, Francesco M Marincola, Masoud H Manjili
EGFR-specific T cell frequencies correlate with EGFR expression in head and neck squamous cell carcinoma
Patrick J Schuler, Petra Boeckers, Rainer Engers, Edwin Boelke, Murat Bas, Jens Greve, Claudia A Dumitru, Goetz F Lehnerdt, Robert L Ferris, Pedro A Andrade Filho, Sven Brandau, Stephan Lang, Theresa L Whiteside, Thomas K Hoffmann
Multiplex serum biomarker assessments: technical and biostatistical issues
Lisa H Butterfield, Douglas M Potter, John M Kirkwood
Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone
Joseph CK Leung, Loretta YY Chan, Sydney CW Tang, Man-Fai Lam, Chui-Wa Chow, Ai-Ing Lim, Kar-Neng Lai
mRNA expression levels and genetic status of genes involved in the EGFR and NF-κB pathways in metastatic non-small-cell lung cancer patients
Mariacarmela Santarpia, Ignacio Magri, Maria Sanchez-Ronco, Carlota Costa, Miguel Angel Molina-Vila, Ana Gimenez-Capitan, Jordi Bertran-Alamillo, Clara Mayo, Susana Benlloch, Santiago Viteri, Amaya Gasco, Nuria Mederos, Enric Carcereny, Miquel Taron, Rafael Rosell
Extremely discrepant mutation spectrum of SLC26A4 between Chinese patients with isolated Mondini deformity and enlarged vestibular aqueduct
Shasha Huang, Dongyi Han, Yongyi Yuan, Guojian Wang, Dongyang Kang, Xin Zhang, Xiaofei Yan, Xiaoxiao Meng, Min Dong, Pu Dai
Bacterial glucuronidase as general marker for oncolytic virotherapy or other biological therapies
Michael Hess, Jochen Stritzker, Barbara Härtl, Julia B Sturm, Ivaylo Gentschev, Aladar A Szalay
Stem cell therapy for idiopathic pulmonary fibrosis: a protocol proposal
Argyris Tzouvelekis, George Koliakos, Paschalis Ntolios, Irene Baira, Evangelos Bouros, Anastasia Oikonomou, Athanassios Zissimopoulos, George Kolios, Despoina Kakagia, Vassilis Paspaliaris, Ioannis Kotsianidis, Marios Froudarakis, Demosthenes Bouros
Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview
Monica Marra, Ignazio M Sordelli, Angela Lombardi, Monica Lamberti, Luciano Tarantino, Aldo Giudice, Paola Stiuso, Alberto Abbruzzese, Rossella Sperlongano, Marina Accardo, Massimo Agresti, Michele Caraglia, Pasquale Sperlongano
Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis
Tara L Spivey, Lorenzo Uccellini, Maria Libera Ascierto, Gabriele Zoppoli, Valeria De Giorgi, Lucia Gemma Delogu, Alyson M Engle, Jaime M Thomas, Ena Wang, Francesco M Marincola, Davide Bedognetti
Combination therapy of renal cell carcinoma or breast cancer patients with dendritic cell vaccine and IL-2: results from a phase I/II trial
Soyoung Baek, Choung-Soo Kim, Sung-Bae Kim, Yong-man Kim, Seog-Woon Kwon, YongMan Kim, HyunSoo Kim, Hyunah Lee
Tumour macrophages as potential targets of bisphosphonates
Thea L Rogers, Ingunn Holen
Safety and feasibility of percutaneous retrograde coronary sinus delivery of autologous bone marrow mononuclear cell transplantation in patients with chronic refractory angina
Jorge Tuma, Roberto Fernández-Viña, Antonio Carrasco, Jorge Castillo, Carlos Cruz, Alvaro Carrillo, Jose Ercilla, Carlos Yarleque, Jaime Cunza, Timothy D Henry, Amit N Patel
Heat shock protein 70/peptide complexes: potent mediators for the generation of antiviral T cells particularly with regard to low precursor frequencies
Sabine Tischer, Megan Basila, Britta Maecker-Kolhoff, Stephan Immenschuh, Mathias Oelke, Rainer Blasczyk, Britta Eiz-Vesper
High expression of HLA-E in colorectal carcinoma is associated with a favorable prognosis
Maria Benevolo, Marcella Mottolese, Elisa Tremante, Francesca Rollo, Maria Grazia Diodoro, Cristiana Ercolani, Isabella Sperduti, Elisa Lo Monaco, Maurizio Cosimelli, Patrizio Giacomini
Six-transmembrane epithelial antigen of the prostate and enhancer of zeste homolog 2 as immunotherapeutic targets for lung cancer
Satoshi Hayashi, Takumi Kumai, Yoshiya Matsuda, Naoko Aoki, Keisuke Sato, Shoji Kimura, Masahiro Kitada, Masatoshi Tateno, Esteban Celis, Hiroya Kobayashi
Chemotherapy-associated thromboembolic risk in cancer outpatients and effect of nadroparin thromboprophylaxis: results of a retrospective analysis of the PROTECHT study
Sandro Barni, Roberto Labianca, Giancarlo Agnelli, Erminio Bonizzoni, Melina Verso, Mario Mandalà, Matteo Brighenti, Fausto Petrelli, Carlo Bianchini, Tania Perrone, Giampietro Gasparini
Evaluation of SLOG/TCI-III pediatric system on target control infusion of propofol
Wan-hua Yang, Hong-bin Gu, Bing Chen, Juan Li, Qiu-wei Fan, Yong-fang Yuan, Xiangdong Wang
Stem cell treatment for patients with autoimmune disease by systemic infusion of culture-expanded autologous adipose tissue derived mesenchymal stem cells
Jeong Chan Ra, Sung Keun Kang, Il Seob Shin, Hyeong Geun Park, Sang Aun Joo, Jeong Geun Kim, Byeong-Cheol Kang, Yong Soon Lee, Ken Nakama, Min Piao, Bertram Sohl, Andras Kurtz
The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism
Rena J Eudy, Vaishali Sahasrabudhe, Kevin Sweeney, Meera Tugnait, Amanda King-Ahmad, Kristen Near, Paula Loria, Mary Ellen Banker, David W Piotrowski, Carine M Boustany-Kari
Correspondence between salivary proteomic pattern and clinical course in primary Sjögren syndrome and non-Hodgkin's lymphoma: a case report
Chiara Baldini, Laura Giusti, Federica Ciregia, Ylenia Da Valle, Camillo Giacomelli, Elena Donadio, Francesco Ferro, Sara Galimberti, Valentina Donati, Laura Bazzichi, Stefano Bombardieri, Antonio Lucacchini
Distribution, characterization, and induction of CD8+ regulatory T cells and IL-17-producing CD8+ T cells in nasopharyngeal carcinoma
Jiang Li, Zhou-Feng Huang, Geng Xiong, Hao-Yuan Mo, Fang Qiu, Hai-Qiang Mai, Qiu-Yan Chen, Jia He, Shu-peng Chen, Li-Min Zheng, Chao-Nan Qian, Yi-Xin Zeng
Long-term fenofibrate treatment impaired glucose-stimulated insulin secretion and up-regulated pancreatic NF-kappa B and iNOS expression in monosodium glutamate-induced obese rats: Is that a latent disadvantage?
Shuai-nan Liu, Quan Liu, Lin-yi Li, Yi Huan, Su-juan Sun, Zhu-fang Shen
Huh-7 cell line as an alternative cultural model for the production of human like erythropoietin (EPO)
Humera Kausar, Sana Gull, Bushra Ijaz, Waqar Ahmad, Muhammad Tahir Sarwar, Zafar Iqbal, Zafar Nawaz, Sheikh Riazuddin, Sajida Hassan
Inhibition of HCV 3a genotype entry through Host CD81 and HCV E2 antibodies
Usman A Ashfaq, Muhammad Qasim, Muhammad Z Yousaf, Muhammad Tariq Awan, Shah Jahan
MicroRNA modulation in complex regional pain syndrome
Irina A Orlova, Guillermo M Alexander, Rehman A Qureshi, Ahmet Sacan, Alessandro Graziano, James E Barrett, Robert J Schwartzman, Seena K Ajit
Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas Ligand pathway
Veerauo V Konkankit, Won Kim, Richard C Koya, Ascia Eskin, Mai-Anh Dam, Stanley Nelson, Antoni Ribas, Linda M Liau, Robert M Prins
Construction and characterisation of a recombinant fowlpox virus that expresses the human papilloma virus L1 protein
Carlo Zanotto, Eleana Pozzi, Sole Pacchioni, Massimiliano Bissa, Carlo De Giuli Morghen, Antonia Radaelli
How scientists use social media to communicate their research
Laura Van Eperen, Francesco M Marincola
Gut microbiota and sirtuins in obesity-related inflammation and bowel dysfunction
Shaheen E Lakhan, Annette Kirchgessner
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
Omid Hamid, Henrik Schmidt, Aviram Nissan, Laura Ridolfi, Steinar Aamdal, Johan Hansson, Michele Guida, David M Hyams, Henry Gómez, Lars Bastholt, Scott D Chasalow, David Berman
Elevated levels of Dickkopf-related protein 3 in seminal plasma of prostate cancer patients
Christoph Zenzmaier, Martin Heitz, Helmut Klocker, Marion Buck, Robert A Gardiner, Peter Berger
Differentiation of breast cancer stem cells by knockdown of CD44: promising differentiation therapy
Phuc V Pham, Nhan LC Phan, Nhung T Nguyen, Nhung H Truong, Thuy T Duong, Dong V Le, Kiet D Truong, Ngoc K Phan
The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas
Andrej Valkov, Thomas K Kilvaer, Sveinung W Sorbye, Tom Donnem, Eivind Smeland, Roy M Bremnes, Lill-Tove Busund
ATP synthase ecto-α-subunit: a novel therapeutic target for breast cancer
Jian Pan, Li-Chao Sun, Yan-Fang Tao, Zhuan Zhou, Xiao-Li Du, Liang Peng, Xing Feng, Jian Wang, Yi-Ping Li, Ling Liu, Shui-Yan Wu, Yan-Lan Zhang, Shao-Yan Hu, Wen-Li Zhao, Xue-Ming Zhu, Guo-Liang Lou, Jian Ni
Molecular features of the complementarity determining region 3 motif of the T cell population and subsets in the blood of patients with chronic severe hepatitis B
Jiezuan Yang, Jianqin He, Haifeng Lu, Li Wei, Sujun Li, Baohong Wang, Hongyan Diao, Lanjuan Li
High dose intermittent sorafenib shows improved efficacy over conventional continuous dose in renal cell carcinoma
Xiaoen Wang, Liang Zhang, S Nahum Goldberg, Manoj Bhasin, Victoria Brown, David C Alsop, Sabina Signoretti, James W Mier, Michael B Atkins, Rupal S Bhatt
Poly I: C-activated dendritic cells that were generated in CellGro for use in cancer immunotherapy trials
Jitka Fučíková, Daniela Rožková, Hana Ulčová, Vít Budinský, Klára Sochorová, Kateřina Pokorná, Jiřina Bartůňková, Radek Špíšek
Granulocyte colony-stimulating factor affects the distribution and clonality of TRGV and TRDV repertoire of T cells and graft-versus-host disease
Li Xuan, Xiuli Wu, Yu Zhang, Zhiping Fan, Yiwen Ling, Fen Huang, Fuhua Zhang, Xiao Zhai, Qifa Liu
Anti-CTLA4 monoclonal antibodies: the past and the future in clinical application
Paolo A Ascierto, Francesco M Marincola, Antoni Ribas
Expression of the Epigenetic factor BORIS (CTCFL) in the Human Genome
Rosalia de Necochea-Campion, Anahit Ghochikyan, Steven F Josephs, Shelly Zacharias, Erik Woods, Feridoun Karimi-Busheri, Doru T Alexandrescu, Chien-Shing Chen, Michael G Agadjanyan, Ewa Carrier
Endogenous interleukin-10 constrains Th17 cells in patients with inflammatory bowel disease
Cailin M Wilke, Lin Wang, Shuang Wei, Ilona Kryczek, Emina Huang, John Kao, Yanwei Lin, Jingyuan Fang, Weiping Zou
Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors
Enrico P Spugnini, Alfonso Baldi, Sabrina Buglioni, Francesca Carocci, Giulia Milesi de Bazzichini, Gianluca Betti, Ilaria Pantaleo, Francesco Menicagli, Gennaro Citro, Stefano Fais
A novel patient-derived intra-femoral xenograft model of bone metastatic prostate cancer that recapitulates mixed osteolytic and osteoblastic lesions
Omer Raheem, Anna A Kulidjian, Christina Wu, Young B Jeong, Tomonori Yamaguchi, Kristen M Smith, Daniel Goff, Heather Leu, Sheldon R Morris, Nicholas A Cacalano, Koichi Masuda, Catriona HM Jamieson, Christopher J Kane, Christina AM Jamieson
Personalized medicine: a patient - centered paradigm
Lotfi Chouchane, Ravinder Mamtani, Ashraf Dallol, Javaid I Sheikh
Genomic sequencing in clinical trials
Karen K Mestan, Leonard Ilkhanoff, Samdeep Mouli, Simon Lin
The King is Dead, Long Live the King: Entering A New Era of Stem Cell Research and Clinical Development
Thomas Ichim, Neil H Riordan, David F Stroncek
Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms
Chor Sang Chim, Thomas S Wan, Kwan Yeung Wong, Tsz Kin Fung, Hans G Drexler, Kit Fai Wong
Optimizing parameters for clinical-scale production of high IL-12 secreting dendritic cells pulsed with oxidized whole tumor cell lysate
Cheryl L-L Chiang, Dawn A Maier, Lana E Kandalaft, Andrea L Brennan, Evripidis Lanitis, Qunrui Ye, Bruce L Levine, Brian J Czerniecki, Daniel J Powell Jr, George Coukos
Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes status
Bernice Lo, Austin DE Swafford, Kimberly A Shafer-Weaver, Lawrence F Jerome, Luba Rakhlin, Douglas R Mathern, Conor A Callahan, Ping Jiang, Lucy J Davison, Helen E Stevens, Carrie L Lucas, Jill White, Reid von Borstel, John A Todd, Michael J Lenardo
Defining epitope coverage requirements for T cell-based HIV vaccines: Theoretical considerations and practical applications
Jeffrey R Currier, Merlin L Robb, Nelson L Michael, Mary A Marovich
Astrocyte elevated gene-1 (AEG-1) is a marker for aggressive salivary gland carcinoma
Wen-Ting Liao, Ling Guo, Yi Zhong, Yan-Heng Wu, Jun Li, Li-Bing Song
Identification and manipulation of tumor associated macrophages in human cancers
Moniek Heusinkveld, Sjoerd H van der Burg
TLR4 dependent heparan sulphate-induced pancreatic inflammatory response is IRF3-mediated
Hamid Akbarshahi, Jakob BF Axelsson, Katarzyna Said, Anders Malmström, Hans Fischer, Roland Andersson
Calcium-sensing receptor and calcium kidney stones
Giuseppe Vezzoli, Annalisa Terranegra, Francesco Rainone, Teresa Arcidiacono, Mario Cozzolino, Andrea Aloia, Elena Dogliotti, Daniele Cusi, Laura Soldati
Definition of the viral targets of protective HIV-1-specific T cell responses
Beatriz Mothe, Anuska Llano, Javier Ibarrondo, Marcus Daniels, Cristina Miranda, Jennifer Zamarreño, Vanessa Bach, Rosario Zuniga, Susana Pérez-Álvarez, Christoph T Berger, Maria C Puertas, Javier Martinez-Picado, Morgane Rolland, Marilu Farfan, James J Szinger, William H Hildebrand, Otto O Yang, Victor Sanchez-Merino, Chanson J Brumme, Zabrina L Brumme, David Heckerman, Todd M Allen, James I Mullins, Guadalupe Gómez, Philip J Goulder, Bruce D Walker, Jose M Gatell, Bonaventura Clotet, Bette T Korber, Jorge Sanchez, Christian Brander
Public health and valorization of genome-based technologies: a new model
Jonathan A Lal, Tobias Schulte in den Bäumen, Servaas A Morré, Angela Brand
Clinical outcomes of active specific immunotherapy in advanced colorectal cancer and suspected minimal residual colorectal cancer: a meta-analysis and system review
Benqiang Rao, Minyan Han, Lei Wang, Xiaoyan Gao, Jun Huang, Meijin Huang, Huanliang Liu, Jianping Wang
Defining the critical hurdles in cancer immunotherapy
Bernard A Fox, Dolores J Schendel, Lisa H Butterfield, Steinar Aamdal, James P Allison, Paolo Antonio Ascierto, Michael B Atkins, Jirina Bartunkova, Lothar Bergmann, Neil Berinstein, Cristina C Bonorino, Ernest Borden, Jonathan L Bramson, Cedrik M Britten, Xuetao Cao, William E Carson, Alfred E Chang, Dainius Characiejus, A Raja Choudhury, George Coukos, Tanja de Gruijl, Robert O Dillman, Harry Dolstra, Glenn Dranoff, Lindy G Durrant, James H Finke, Jerome Galon, Jared A Gollob, Cécile Gouttefangeas, Fabio Grizzi, Michele Guida, Leif Håkansson, Kristen Hege, Ronald B Herberman, F Stephen Hodi, Axel Hoos, Christoph Huber, Patrick Hwu, Kohzoh Imai, Elizabeth M Jaffee, Sylvia Janetzki, Carl H June, Pawel Kalinski, Howard L Kaufman, Koji Kawakami, Yutaka Kawakami, Ulrich Keilholtz, Samir N Khleif, Rolf Kiessling, Beatrix Kotlan, Guido Kroemer, Rejean Lapointe, Hyam I Levitsky, Michael T Lotze, Cristina Maccalli, Michele Maio, Jens-Peter Marschner, Michael J Mastrangelo, Giuseppe Masucci, Ignacio Melero, Cornelius Melief, William J Murphy, Brad Nelson, Andrea Nicolini, Michael I Nishimura, Kunle Odunsi, Pamela S Ohashi, Jill O'Donnell-Tormey, Lloyd J Old, Christian Ottensmeier, Michael Papamichail, Giorgio Parmiani, Graham Pawelec, Enrico Proietti, Shukui Qin, Robert Rees, Antoni Ribas, Ruggero Ridolfi, Gerd Ritter, Licia Rivoltini, Pedro J Romero, Mohamed L Salem, Rik J Scheper, Barbara Seliger, Padmanee Sharma, Hiroshi Shiku, Harpreet Singh-Jasuja, Wenru Song, Per Thor Straten, Hideaki Tahara, Zhigang Tian, Sjoerd H van Der Burg, Paul von Hoegen, Ena Wang, Marij JP Welters, Hauke Winter, Tara Withington, Jedd D Wolchok, Weihua Xiao, Laurence Zitvogel, Heinz Zwierzina, Francesco M Marincola, Thomas F Gajewski, Jon M Wigginton, Mary L Disis
Cathepsin B: a potential prognostic marker for inflammatory breast cancer
Mohamed A Nouh, Mona M Mohamed, Mohamed El-Shinawi, Mohamed A Shaalan, Dora Cavallo-Medved, Hussein M Khaled, Bonnie F Sloane
Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins
Tonia Buonomo, Laura Carraresi, Mara Rossini, Rosanna Martinelli
Translational Medicine is developing in China: A new venue for collaboration
Xiangdong Wang, Ena Wang, Francesco M Marincola
Frequency and spectrum of mitochondrial 12S rRNA variants in 440 Han Chinese hearing impaired pediatric subjects from two otology clinics
Zhisen Shen, Jing Zheng, Bobei Chen, Guanghua Peng, Ting Zhang, Shasha Gong, Yi Zhu, Chuqin Zhang, Ronghua Li, Li Yang, Jianjin Zhou, Ting Cai, Lihua Jin, Jianxin Lu, Min-Xin Guan
High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma
Mei Li, Rong-Zhen Luo, Jie-Wei Chen, Yun Cao, Jia-Bin Lu, Jie-Hua He, Qiu-Liang Wu, Mu-Yan Cai
Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization
Tom Donnem, Katrine Eklo, Thomas Berg, Sveinung W Sorbye, Kenneth Lonvik, Samer Al-Saad, Khalid Al-Shibli, Sigve Andersen, Helge Stenvold, Roy M Bremnes, Lill-Tove Busund
Evaluation of the anti-angiogenic properties of the new selective αVβ3 integrin antagonist RGDechiHCit
Gaetano Santulli, Maria Felicia Basilicata, Mariarosaria De Simone, Carmine Del Giudice, Antonio Anastasio, Daniela Sorriento, Michele Saviano, Annarita Del Gatto, Bruno Trimarco, Carlo Pedone, Laura Zaccaro, Guido Iaccarino
Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent
Tomohisa Horibe, Masayuki Kohno, Mari Haramoto, Koji Ohara, Koji Kawakami
Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages
Cecilia Lässer, Vesta Seyed Alikhani, Karin Ekström, Maria Eldh, Patricia Torregrosa Paredes, Apostolos Bossios, Margareta Sjöstrand, Susanne Gabrielsson, Jan Lötvall, Hadi Valadi
Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning
Anastasia Efimenko, Ekaterina Starostina, Natalia Kalinina, Alexandra Stolzing
Myocardium-derived conditioned medium improves left ventricular function in rodent acute myocardial infarction
Steve Leu, Ying-Hsien Kao, Cheuk-Kwan Sun, Yu-Chun Lin, Tzu-Hsien Tsai, Li-Teh Chang, Sarah Chua, Kuo-Ho Yeh, Chiung-Jen Wu, Morgan Fu, Hon-Kan Yip
Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion
Kyriakos Anastasiadis, Polychronis Antonitsis, Helena Argiriadou, Georgios Koliakos, Argyrios Doumas, Andre Khayat, Christos Papakonstantinou, Stephen Westaby
Etiopathology of chronic tubular, glomerular and renovascular nephropathies: Clinical implications
José M López-Novoa, Ana B Rodríguez-Peña, Alberto Ortiz, Carlos Martínez-Salgado, Francisco J López Hernández
Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals - the Swiss HIV Cohort Study
Jan Fehr, Tracy R Glass, Séverine Louvel, François Hamy, Hans H Hirsch, Viktor von Wyl, Jürg Böni, Sabine Yerly, Philippe Bürgisser, Matthias Cavassini, Christoph A Fux, Bernard Hirschel, Pietro Vernazza, Gladys Martinetti, Enos Bernasconi, Huldrych F Günthard, Manuel Battegay, Heiner C Bucher, Thomas Klimkait
Analysis of machine perfusion benefits in kidney grafts: a preclinical study
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