Ausgabe 1/2013
Inhalt (317 Artikel)
A global resource to translational medicine: the International Park of Translational Medicine and BioMedicine (IPTBM)
Xiaodan Wu, Francesco M Marincola, Michael N Liebman, Xiangdong Wang
JTM’s Tumor immunology goes broad: announcing the Immunobiology and Immunotherapy section
Adrian Bot, Francesco Marincola, Pedro Romero
Sildenafil restores endothelial function in the apolipoprotein E knockout mouse
Camille M Balarini, Marcos A Leal, Isabele B S Gomes, Thiago M C Pereira, Agata L Gava, Silvana S Meyrelles, Elisardo C Vasquez
T-cell activation by treatment of cancer patients with EMD 521873 (Selectikine), an IL-2/anti-DNA fusion protein
Julien Laurent, Cedric Touvrey, Silke Gillessen, Magali Joffraud, Manuela Vicari, Caroline Bertrand, Stefano Ongarello, Bernd Liedert, Elisa Gallerani, Joachim Beck, Aurelius Omlin, Cristiana Sessa, Sonia Quaratino, Roger Stupp, Ulrike S Gnad-Vogt, Daniel E Speiser
Chemokine CXCL14 is associated with prognosis in patients with colorectal carcinoma after curative resection
Jun Zeng, Xudan Yang, Lin Cheng, Rui Liu, Yunlong Lei, Dandan Dong, Fanghua Li, Quek Choon Lau, Longfei Deng, Edouard C Nice, Ke Xie, Canhua Huang
Predictive value of pre-procedural autoantibodies against M2-muscarinic acetylcholine receptor for recurrence of atrial fibrillation one year after radiofrequency catheter ablation
Changhong Zou, Zhiyong Zhang, Wenmin Zhao, Guang Li, Guiling Ma, Xinchun Yang, Jianjun Zhang, Lin Zhang
Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients
Shuwei Qiu, Sheng Lin, Dan Hu, Yimin Feng, Yang Tan, Ying Peng
NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways
Maryam Zadeh-Khorasani, Thomas Nolte, Thomas D Mueller, Markos Pechlivanis, Franziska Rueff, Andreas Wollenberg, Gert Fricker, Eckhard Wolf, Matthias Siebeck, Roswitha Gropp
Lack of association of the HMGA1 IVS5-13insC variant with type 2 diabetes in an ethnically diverse hypertensive case control cohort
Jason H Karnes, Taimour Y Langaee, Caitrin W McDonough, Shin-Wen Chang, Miguel Ramos, James R Catlin Jr, Octavio E Casanova, Yan Gong, Carl J Pepine, Julie A Johnson, Rhonda M Cooper-DeHoff
Vascularity of primary and metastatic renal cell carcinoma specimens
Saadia A Aziz, Joshua Sznol, Adebowale Adeniran, John W Colberg, Robert L Camp, Harriet M Kluger
Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study
Nicolas Marincek, Ann-Catherine Jörg, Philippe Brunner, Christian Schindler, Michael T Koller, Christoph Rochlitz, Jan Müller-Brand, Helmut R Maecke, Matthias Briel, Martin A Walter
The role of human umbilical cord tissue-derived mesenchymal stromal cells (UCX®) in the treatment of inflammatory arthritis
Jorge M Santos, Rita N Bárcia, Sandra I Simões, Manuela M Gaspar, Susana Calado, Ana Água-Doce, Sílvia CP Almeida, Joana Almeida, Mariana Filipe, Mariana Teixeira, José P Martins, Luís Graça, Maria EM Cruz, Pedro Cruz, Helder Cruz
Neural stem cell-like cells derived from autologous bone mesenchymal stem cells for the treatment of patients with cerebral palsy
Guojun Chen, Yali Wang, Zhenyu Xu, Feng Fang, Renmei Xu, Yue Wang, Xiaoli Hu, Lixing Fan, Houqi Liu
Advanced health biotechnologies in Thailand: redefining policy directions
Román Pérez Velasco, Usa Chaikledkaew, Chaw Yin Myint, Roongnapa Khampang, Sripen Tantivess, Yot Teerawattananon
Correlations between cytoplasmic CSE1L in neoplastic colorectal glands and depth of tumor penetration and cancer stage
Cheng-Jeng Tai, Tzu-Cheng Su, Ming-Chung Jiang, Hung-Chang Chen, Shing-Chuan Shen, Woan-Ruoh Lee, Ching-Fong Liao, Ying-Chun Chen, Shu-Hui Lin, Li-Tzu Li, Ko-Hung Shen, Chung-Min Yeh, Kun-Tu Yeh, Ching-Hsiao Lee, Hsin-Yi Shih, Chun-Chao Chang
TNF gene polymorphisms in cystic fibrosis patients: contribution to the disease progression
Galina Shmarina, Alexander Pukhalsky, Nika Petrova, Ekaterina Zakharova, Lucine Avakian, Nikolai Kapranov, Vladimir Alioshkin
ARA290, a non-erythropoietic EPO derivative, attenuates renal ischemia/reperfusion injury
Willem G van Rijt, Gertrude J Nieuwenhuijs-Moeke, Harry van Goor, Bente Jespersen, Petra J Ottens, Rutger J Ploeg, Henri GD Leuvenink
Id1 and Id3 co-expression correlates with clinical outcome in stage III-N2 non-small cell lung cancer patients treated with definitive chemoradiotherapy
Eduardo Castañon, Joaquim Bosch-Barrera, Inés López, Víctor Collado, Marta Moreno, José María López-Picazo, Leire Arbea, María Dolores Lozano, Alfonso Calvo, Ignacio Gil-Bazo
Optimizing patient derived mesenchymal stem cells as virus carriers for a Phase I clinical trial in ovarian cancer
Emily K Mader, Greg Butler, Sean C Dowdy, Andrea Mariani, Keith L Knutson, Mark J Federspiel, Stephen J Russell, Evanthia Galanis, Allan B Dietz, Kah-Whye Peng
Brain death induces renal expression of heme oxygenase-1 and heat shock protein 70
Leon FA van Dullemen, Eelke M Bos, Theo A Schuurs, Harm H Kampinga, Rutger J Ploeg, Harry van Goor, Henri GD Leuvenink
Clinical analysis of selected complement-derived molecules in human adipose tissue
Wojciech Błogowski, Marta Budkowska, Daria Sałata, Karol Serwin, Barbara Dołęgowska, Marek Łokaj, Piotr Prowans, Teresa Starzyńska
High efficacy of CpG-ODN, Cetuximab and Cisplatin combination for very advanced ovarian xenograft tumors
Michele Sommariva, Michelandrea de Cesare, Alessandra Meini, Alessandra Cataldo, Nadia Zaffaroni, Elda Tagliabue, Andrea Balsari
Important steps to improve translation from medical research to health policy
Fan Jiang, Jun Zhang, Xiangdong Wang, Xiaoming Shen
Prognostication of prostate cancer based on TOP2A protein and gene assessment: TOP2A in prostate cancer
Marina França de Resende, Samantha Vieira, Ludmilla Thomé Domingos Chinen, Francesco Chiappelli, Francisco Paulo da Fonseca, Gustavo Cardoso Guimarães, Fernando Augusto Soares, Ivan Neves, Simone Pagotty, Peter A Pellionisz, Andre Barkhordarian, Xenia Brant, Rafael Malagoli Rocha
Improvement of left ventricular remodeling after myocardial infarction with eight weeks L-thyroxine treatment in rats
Yue-Feng Chen, Nathan Y Weltman, Xiang Li, Steven Youmans, David Krause, Anthony Martin Gerdes
Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia
Hussein Fayyad-Kazan, Nizar Bitar, Mehdi Najar, Philippe Lewalle, Mohammad Fayyad-Kazan, Rabih Badran, Eva Hamade, Ahmad Daher, Nader Hussein, Rim ELDirani, Fadwa Berri, Luc Vanhamme, Arsène Burny, Philippe Martiat, Redouane Rouas, Bassam Badran
Mesenchymal stem cells enhance ovarian cancer cell infiltration through IL6 secretion in an amniochorionic membrane based 3D model
Cyril Touboul, Raphael Lis, Halema Al Farsi, Christophe M Raynaud, Mohamed Warfa, Hamda Althawadi, Eliane Mery, Massoud Mirshahi, Arash Rafii
Adipose stromal cells primed with hypoxia and inflammation enhance cardiomyocyte proliferation rate in vitro through STAT3 and Erk1/2
Ewa Przybyt, Guido Krenning, Marja GL Brinker, Martin C Harmsen
Comparison of the diagnostic values of circulating steroid hormones, VEGF-A, PIGF, and ADAM12 in women with ectopic pregnancy
Shien Zou, Xin Li, Yi Feng, Shan Sun, Jin Li, Emil Egecioglu, Håkan Billig, Ruijin Shao
Roles of histone hypoacetylation in LAT expression on T cells and Th2 polarization in allergic asthma
Cheng-ye Li, Juan Peng, Lian-pin Ren, Li-xing Gan, Xiao-jiong Lu, Qian Liu, Wen Gu, Xue-jun Guo
Immune cell profile of sentinel lymph nodes in patients with malignant melanoma – FOXP3+ cell density in cases with positive sentinel node status is associated with unfavorable clinical outcome
Anita Mohos, Tímea Sebestyén, Gabriella Liszkay, Vanda Plótár, Szabolcs Horváth, István Gaudi, Andrea Ladányi
Targeting of interleukin-13 receptor α2 for treatment of head and neck squamous cell carcinoma induced by conditional deletion of TGF-β and PTEN signaling
Bradford Hall, Hideyuki Nakashima, Zhi-Jun Sun, Yuki Sato, Yansong Bian, Syed R Husain, Raj K Puri, Ashok B Kulkarni
Phase III randomized study of fotemustine and dacarbazine versus dacarbazine with or without interferon-α in advanced malignant melanoma
Antonio Daponte, Simona Signoriello, Luigi Maiorino, Bruno Massidda, Ester Simeone, Antonio Maria Grimaldi, Corrado Caracò, Giuseppe Palmieri, Antonio Cossu, Gerardo Botti, Antonella Petrillo, Secondo Lastoria, Ernesta Cavalcanti, Pasquale Aprea, Nicola Mozzillo, Ciro Gallo, Giuseppe Comella, Paolo Antonio Ascierto
Association between peripheral T-Lymphocyte activation and impaired bone mineral density in HIV-infected patients
Lidia Gazzola, Giusi Maria Bellistri, Camilla Tincati, Valentina Ierardi, Alessia Savoldi, Angelo Del Sole, Luca Tagliabue, Antonella d’Arminio Monforte, Giulia Marchetti
Induction of human fetal hemoglobin expression by adenosine-2’,3’-dialdehyde
Yinghong He, Gerhard Rank, Miaomiao Zhang, Junyi Ju, Ronghua Liu, Zhen Xu, Fiona Brown, Loretta Cerruti, Chi Ma, Renxiang Tan, Stephen M Jane, Quan Zhao
High intratumoral metastasis-associated in colon cancer-1 expression predicts poor outcomes of cryoablation therapy for advanced hepatocellular carcinoma
Yong-Ping Yang, Jian-Hui Qu, Xiu-Juan Chang, Yin-Ying Lu, Wen-Lin Bai, Zheng Dong, Hong Wang, Lin-Jing An, Zhong-Xian Xu, Chun-Ping Wang, Zhen Zeng, Ke-Qin Hu
Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor
Steven C Katz, Rachel A Burga, Seema Naheed, Lauren A Licata, Mitchell Thorn, Doreen Osgood, Cang T Nguyen, N Joseph Espat, Jonathan A Fletcher, Richard P Junghans
Response of circulating heat shock protein 70 and anti-heat shock protein 70 antibodies to catheter ablation of atrial fibrillation
Jelena Kornej, Claudia Reinhardt, Jedrzej Kosiuk, Arash Arya, Gerhard Hindricks, Volker Adams, Daniela Husser, Andreas Bollmann
Low expression of PTK6/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma
Xue-Kui Liu, Xin-Rui Zhang, Qian Zhong, Man-Zhi Li, Zhi-Min Liu, Zhi-Rui Lin, Di Wu, Mu-Sheng Zeng
Do BRAF inhibitors select for populations with different disease progression kinetics?
Paolo Antonio Ascierto, Ester Simeone, Antonio Maria Grimaldi, Marcello Curvietto, Assunta Esposito, Giuseppe Palmieri, Nicola Mozzillo
Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways
Wenli Yu, Mingwei Sheng, Rubin Xu, Jianjian Yu, Kang Cui, Jingkai Tong, Liying Shi, Hengchang Ren, Hongyin Du
Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors
Claudia Marcela Diaz, Alberto Chiappori, Luigi Aurisicchio, Ansuman Bagchi, Jason Clark, Sheri Dubey, Arthur Fridman, Jesus C Fabregas, John Marshall, Elisa Scarselli, Nicola La Monica, Gennaro Ciliberto, Alberto J Montero
Stem cells: a new paradigm for disease modeling and developing therapies for age-related macular degeneration
Heather Melville, Matthew Carpiniello, Kia Hollis, Andrew Staffaroni, Nady Golestaneh
Endometrial regenerative cells for treatment of heart failure: a new stem cell enters the clinic
Leo Bockeria, Vladimir Bogin, Olga Bockeria, Tatyana Le, Bagrat Alekyan, Erik J Woods, Amalia A Brown, Thomas E Ichim, Amit N Patel
A systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells
Daya Luo, James M Wilson, Nikki Harvel, Jimei Liu, Lirong Pei, Shuang Huang, LesleyAnn Hawthorn, Huidong Shi
SSX2IP promotes metastasis and chemotherapeutic resistance of hepatocellular carcinoma
Pu Li, Ying Lin, Yu Zhang, Zhenggang Zhu, Keke Huo
Clinicopathological characteristics and prognostic analysis of Lauren classification in gastric adenocarcinoma in China
Miao-zhen Qiu, Mu-yan Cai, Dong-sheng Zhang, Zhi-qiang Wang, De-shen Wang, Yu-hong Li, Rui-hua Xu
Expansion of antibody secreting cells and modulation of neutralizing antibody activity in HIV infected individuals undergoing structured treatment interruptions
Anuska Llano, Jorge Carrillo, Beatriz Mothe, Lidia Ruiz, Silvia Marfil, Elisabet García, Eloísa Yuste, Víctor Sánchez, Bonaventura Clotet, Julià Blanco, Christian Brander
Invasive colon cancer, but not non-invasive adenomas induce a gradient effect of Wnt pathway receptor frizzled 1 (Fz1) expression in the tumor microenvironment
Kestutis Planutis, Marina Planutiene, Anthony V Nguyen, Mary Pat Moyer, Randall F Holcombe
Journal of translational medicine reviewer acknowledgement 2012
Francesco Marincola
Antitumor effects of L-BLP25 Antigen-Specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model
Gregory T Wurz, Audrey M Gutierrez, Brittany E Greenberg, Daniel P Vang, Stephen M Griffey, Chiao-Jung Kao, Michael Wolf, Michael W DeGregorio
pSTAT3: a target biomarker to study the pharmacology of the anti-IL-21R antibody ATR-107 in human whole blood
Ming Zhu, Susan Pleasic-Williams, Tsung H Lin, David A Wunderlich, John B Cheng, Jaime L Masferrer
Highly conserved antigenic epitope regions of hemagglutinin and neuraminidase genes between 2009 H1N1 and seasonal H1N1 influenza: vaccine considerations
Ping Huang, Shouyi Yu, Changyou Wu, Lijun Liang
Malnutrition, a new inducer for arterial calcification in hemodialysis patients?
Kun Zhang, Gang Cheng, Xue Cai, Jie Chen, Ying Jiang, Tong Wang, Jingfeng Wang, Hui Huang
Dynamically expressed microRNA-15b modulates the activities of CD8+ T lymphocytes in mice with Lewis lung carcinoma
Guocheng Zhong, Xiaoming Cheng, Haixia Long, Luhang He, Wei Qi, Tong Xiang, Zhongquan Zhao, Bo Zhu
Microenvironment generated during EGFR targeted killing of pancreatic tumor cells by ATC inhibits myeloid-derived suppressor cells through COX2 and PGE2 dependent pathway
Archana Thakur, Dana Schalk, Elyse Tomaszewski, Sri Vidya Kondadasula, Hiroshi Yano, Fazlul H Sarkar, Lawrence G Lum
The additional facet of immunoscore: immunoprofiling as a possible predictive tool for cancer treatment
Paolo A Ascierto, Mariaelena Capone, Walter J Urba, Carlo B Bifulco, Gerardo Botti, Alessandro Lugli, Francesco M Marincola, Gennaro Ciliberto, Jérôme Galon, Bernard A Fox
Stress hormones promote growth of B16-F10 melanoma metastases: an interleukin 6- and glutathione-dependent mechanism
Soraya L Valles, María Benlloch, María L Rodriguez, Salvador Mena, José A Pellicer, Miguel Asensi, Elena Obrador, José M Estrela
Significantly fewer protein functional changing variants for lipid metabolism in Africans than in Europeans
Cheng Xue, Xiaoming Liu, Yun Gong, Yuhai Zhao, Yun-Xin Fu
Predictive value of the SLC22A18 protein expression in glioblastoma patients receiving temozolomide therapy
Sheng-Hua Chu, Yan-Bin Ma, Dong-Fu Feng, Zhi-Qiang Li, Pu-Cha Jiang
Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome
Marta Curriu, Jorge Carrillo, Marta Massanella, Josepa Rigau, José Alegre, Jordi Puig, Ana M Garcia-Quintana, Jesus Castro-Marrero, Eugènia Negredo, Bonaventura Clotet, Cecilia Cabrera, Julià Blanco
In silico approaches for designing highly effective cell penetrating peptides
Ankur Gautam, Kumardeep Chaudhary, Rahul Kumar, Arun Sharma, Pallavi Kapoor, Atul Tyagi, Gajendra P S Raghava
Clinical implication of centrosome amplification and expression of centrosomal functional genes in multiple myeloma
Elena Dementyeva, Fedor Kryukov, Lenka Kubiczkova, Pavel Nemec, Sabina Sevcikova, Ivana Ihnatova, Jiri Jarkovsky, Jiri Minarik, Zdena Stefanikova, Petr Kuglik, Roman Hajek
Comparing the angiogenic potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells
Mo Dao, Ciara C Tate, Michael McGrogan, Casey C Case
Cytokine-induced killer cells promote antitumor immunity
Jingting Jiang, Changping Wu, Binfeng Lu
Erratum to: phase 1 clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibtion
Erika Hamilton, Kimberly Blackwell, Amy C Hobeika, Timothy M Clay, Gloria Broadwater, Xiu-Rong Ren, Wei Chen, Henry Castro, Frederic Lehmann, Neil Spector, Junping Wei, Takuya Osada, H Kim Lyerly, Michael A Morse
Growth inhibition of different human colorectal cancer xenografts after a single intravenous injection of oncolytic vaccinia virus GLV-1h68
Klaas Ehrig, Mehmet O Kilinc, Nanhai G Chen, Jochen Stritzker, Lisa Buckel, Qian Zhang, Aladar A Szalay
Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC
Chandan Verma, Jennifer M Eremin, Adrian Robins, Andrew J Bennett, Gerard P Cowley, Mohamed A El-Sheemy, Jibril A Jibril, Oleg Eremin
T and NK cells: two sides of tumor immunoevasion
Doriana Fruci, Elisa Lo Monaco, Loredana Cifaldi, Franco Locatelli, Elisa Tremante, Maria Benevolo, Patrizio Giacomini
A CD19/Fc fusion protein for detection of anti-CD19 chimeric antigen receptors
Satiro N De Oliveira, Jiexin Wang, Christine Ryan, Sherie L Morrison, Donald B Kohn, Roger P Hollis
The expressions of MIF and CXCR4 protein in tumor microenvironment are adverse prognostic factors in patients with esophageal squamous cell carcinoma
Lin Zhang, Shu-Biao Ye, Gang Ma, Xiao-Feng Tang, Shi-Ping Chen, Jia He, Wan-Li Liu, Dan Xie, Yi-Xin Zeng, Jiang Li
Shedding LIGHT (TNFSF14) on the tumor microenvironment of colorectal cancer liver metastases
Jian Zhong Qin, Vivek Upadhyay, Bellur Prabhakar, Ajay V Maker
Development of a robust flow cytometry-based pharmacodynamic assay to detect phospho-protein signals for phosphatidylinositol 3-kinase inhibitors in multiple myeloma
Congfen Li, Chikara Takahashi, Liangxuan Zhang, Mahrukh Huseni, Basha Stankovich, Haider Mashhedi, Joanna Lee, Dorothy French, Jeff Eastham Anderson, Doris Kim, Kathy Howell, Matthew J Brauer, Marcin Kowanetz, Yibing Yan, Eric Humke, Allen Ebens, Garret Hampton, Mark R Lackner, Priti Hegde, Shidong Jia
Cardioprotective effect of ritonavir, an antiviral drug, in isoproterenol induced myocardial necrosis: a new therapeutic implication
Prachi Gupta, Abhinav Kanwal, Uday Kumar Putcha, Yogesh Bulani, Bhavesh Sojitra, Tarak Nath Khatua, Madhusudana Kuncha, Sanjay Kumar Banerjee
Implementation of the CDC translational informatics platform - from genetic variants to the national Swedish Rheumatology Quality Register
Imad Abugessaisa, David Gomez-Cabrero, Omri Snir, Staffan Lindblad, Lars Klareskog, Vivianne Malmström, Jesper Tegnér
IL-21 promotes the expansion of CD27+CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells
Saskia JAM Santegoets, Annelies W Turksma, Megan M Suhoski, Anita GM Stam, Steve M Albelda, Erik Hooijberg, Rik J Scheper, Alfons JM van den Eertwegh, Winald R Gerritsen, Daniel J Powell Jr, Carl H June, Tanja D de Gruijl
Basigin-2 is the predominant basigin isoform that promotes tumor cell migration and invasion and correlates with poor prognosis in epithelial ovarian cancer
Shu-Hua Zhao, Yu Wang, Li Wen, Zhen-Bo Zhai, Zhen-Hua Ai, Nian-Ling Yao, Li Wang, Wen-Chao Liu, Bi-Liang Chen, Yu Li, Hong Yang
Intra-osseous injection of donor mesenchymal stem cell (MSC) into the bone marrow in living donor kidney transplantation; a pilot study
Hyunah Lee, Jae Berm Park, Sanghoon Lee, Soyoung Baek, HyunSoo Kim, Sung Joo Kim
High EGFR copy number predicts benefits from tyrosine kinase inhibitor treatment for non-small cell lung cancer patients with wild-type EGFR
Fang Wang, Sha Fu, Qiong Shao, Yan-Bin Zhou, Xiao Zhang, Xu Zhang, Cong Xue, Jian-Guang Lin, Li-Xia Huang, Li Zhang, Wei-Min Zhang, Jian-Yong Shao
Effects of sevoflurane postconditioning on cell death, inflammation and TLR expression in human endothelial cells exposed to LPS
Raquel Rodríguez-González, Aurora Baluja, Sonia Veiras Del Río, Alfonso Rodríguez, Jaime Rodríguez, Manuel Taboada, David Brea, Julián Álvarez
Maintenance of “stem cell” features of cartilage cell sub-populations during in vitro propagation
Karin Benz, Claudia Stippich, Christian Freudigmann, Juergen A Mollenhauer, Wilhelm K Aicher
Hirsutanol A, a novel sesquiterpene compound from fungus Chondrostereum sp., induces apoptosis and inhibits tumor growth through mitochondrial-independent ROS production: Hirsutanol A inhibits tumor growth through ROS production
Fen Yang, Wen-Dan Chen, Rong Deng, Hui Zhang, Jun Tang, Ke-Wei Wu, Dan-Dan Li, Gong-Kan Feng, Wen-Jian Lan, Hou-Jin Li, Xiao-Feng Zhu
Race and gender variation in response to evoked inflammation
Jane F Ferguson, Parth N Patel, Rhia Y Shah, Claire K Mulvey, Ram Gadi, Prabhjot S Nijjar, Haris M Usman, Nehal N Mehta, Rachana Shah, Stephen R Master, Kathleen J Propert, Muredach P Reilly
A three-gene signature as potential predictive biomarker for irinotecan sensitivity in gastric cancer
Jie Shen, Jia Wei, Hao Wang, Guofeng Yue, Lixia Yu, Yang Yang, Li Xie, Zhengyun Zou, Xiaoping Qian, Yitao Ding, Wenxian Guan, Baorui Liu
Gene expression profiling of whole blood in ipilimumab-treated patients for identification of potential biomarkers of immune-related gastrointestinal adverse events
Vafa Shahabi, David Berman, Scott D Chasalow, Lisu Wang, Zenta Tsuchihashi, Beihong Hu, Lisa Panting, Maria Jure-Kunkel, Rui-Ru Ji
Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in mice
Ghazanfar Ali Nasir, Sadia Mohsin, Mohsin Khan, Sulaiman Shams, Gibran Ali, Shaheen N Khan, Sheikh Riazuddin
Cardioprotective effects of lixisenatide in rat myocardial ischemia-reperfusion injury studies
Paulus Wohlfart, Wolfgang Linz, Thomas Hübschle, Dominik Linz, Jochen Huber, Sibylle Hess, Daniel Crowther, Ulrich Werner, Hartmut Ruetten
Systemically administered liposome-encapsulated Ad-PEDF potentiates the anti-cancer effects in mouse lung metastasis melanoma
Hua-shan Shi, Li-ping Yang, Wei Wei, Xiao-qing Su, Xiao-peng Li, Meng Li, Shun-tao Luo, Hai-long Zhang, Lian Lu, Yong-qiu Mao, Bing Kan, Li Yang
Extracellular matrix proteins and displacement of cultured fibroblasts from duodenal biopsies in celiac patients and controls
Leda Roncoroni, Luca Elli, Maria Teresa Bardella, Gianluca Perrucci, Michele Ciulla, Vincenza Lombardo, Carolina Tomba, Dario Conte, Luisa Doneda
Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: evidence of inflammatory pathology
Elizabeth Ann Stringer, Katharine Susanne Baker, Ian R Carroll, Jose G Montoya, Lily Chu, Holden T Maecker, Jarred W Younger
L1R, A27L, A33R and B5R vaccinia virus genes expressed by fowlpox recombinants as putative novel orthopoxvirus vaccines
Sole Maria Pacchioni, Massimiliano Bissa, Carlo Zanotto, Carlo De Giuli Morghen, Elena Illiano, Antonia Radaelli
Multiple therapeutic peptide vaccines consisting of combined novel cancer testis antigens and anti-angiogenic peptides for patients with non-small cell lung cancer
Hiroyuki Suzuki, Mitsuro Fukuhara, Takumi Yamaura, Satoshi Mutoh, Naoyuki Okabe, Hiroshi Yaginuma, Takeo Hasegawa, Atsushi Yonechi, Jun Osugi, Mika Hoshino, Takashi Kimura, Mitsunori Higuchi, Yutaka Shio, Kazuya Ise, Kazuyoshi Takeda, Mitsukazu Gotoh
Annexin A1 protein regulates the expression of PMVEC cytoskeletal proteins in CBDL rat serum-induced pulmonary microvascular remodeling
Bin Yi, Jing Zeng, Guansong Wang, Guisheng Qian, Kaizhi Lu
Serum thiols and cardiovascular risk scores: a combined assessment of transsulfuration pathway components and substrate/product ratios
Arduino A Mangoni, Angelo Zinellu, Ciriaco Carru, John R Attia, Marc McEvoy
BMP4, a strong better prognosis predictor, has a subtype preference and cell development association in gliomas
Zhaoshi Bao, Chuanbao Zhang, Wei Yan, Yanwei Liu, Mingyang Li, Wei Zhang, Tao Jiang
Expression of gamma-aminobutyric acid receptors on neoplastic growth and prediction of prognosis in non-small cell lung cancer
Xiaoxue Zhang, Rong Zhang, Yuanjie Zheng, Jianfei Shen, Dakai Xiao, Jin Li, Xiaoshun Shi, Liyan Huang, Hailing Tang, Jun Liu, Jianxing He, Haibo Zhang
Next-generation tissue microarray (ngTMA) increases the quality of biomarker studies: an example using CD3, CD8, and CD45RO in the tumor microenvironment of six different solid tumor types
Inti Zlobec, Viktor H Koelzer, Heather Dawson, Aurel Perren, Alessandro Lugli
Effects of age on noninvasive assessments of vascular function in nonhuman primates: implications for translational drug discovery
Delvin R Knight Jr, Andrew H Smith, Richard L Schroeder, Chunli Huang, David A Beebe, Sharon A Sokolowski, Miao Wang
Treatment of malignant effusion by oncolytic virotherapy in an experimental subcutaneous xenograft model of lung cancer
Stephanie Weibel, Elisabeth Hofmann, Thomas Christian Basse-Luesebrink, Ulrike Donat, Carolin Seubert, Marion Adelfinger, Prisca Gnamlin, Christina Kober, Alexa Frentzen, Ivaylo Gentschev, Peter Michael Jakob, Aladar A Szalay
Activation of axonal Kv7 channels in human peripheral nerve by flupirtine but not placebo - therapeutic potential for peripheral neuropathies: results of a randomised controlled trial
Johannes Fleckenstein, Ruth Sittl, Beate Averbeck, Philip M Lang, Dominik Irnich, Richard W Carr
A Lectin-EGF antibody promotes regulatory T cells and attenuates nephrotoxic nephritis via DC-SIGN on dendritic cells
Minchao Cai, Jing Wu, Chaoming Mao, Jianmin Ren, Pu Li, Xiao Li, Jiuchang Zhong, Chundi Xu, Tong Zhou
SATB1 is overexpressed in metastatic prostate cancer and promotes prostate cancer cell growth and invasion
Lijun Mao, Chunhua Yang, Junqi Wang, Wang Li, Rumin Wen, Jiacun Chen, Junnian Zheng
VPAC1 receptor expression in peripheral blood mononuclear cells in a human endotoxemia model
Angela Storka, Bernhard Burian, Gerhard Führlinger, Breanna Clive, Terri Sun, Richard Crevenna, Andrea Gsur, Wilhelm Mosgöller, Michael Wolzt
Nutrition in calcium nephrolithiasis
Elena Dogliotti, Giuseppe Vezzoli, Antonio Nouvenne, Tiziana Meschi, Annalisa Terranegra, Alessandra Mingione, Caterina Brasacchio, Benedetta Raspini, Daniele Cusi, Laura Soldati
The role of globular heads of the C1q receptor in HPV 16 E2-induced human cervical squamous carcinoma cell apoptosis is associated with p38 MAPK/JNK activation
Ling-juan Gao, Ping-qing Gu, Wei Zhao, Wen-yan Ding, Xue-qing Zhao, Shu-yu Guo, Tian-ying Zhong
Eosinophils affect functions of in vitro-activated human CD3-CD4+ T cells
Issam Harfi, Liliane Schandené, Sarah Dremier, Florence Roufosse
Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI)
Nishat Siddiqi, Margaret Bruce, Christopher J Neil, Baljit Jagpal, Graeme Maclennon, Seonaidh C Cotton, Sofia A Papadopoulo, Nicholas Bunce, Pitt Lim, Konstantin Schwarz, Satnam Singh, David Hildick-Smith, John D Horowitz, Melanie Madhani, Nicholas Boon, Juan-Carlos Kaski, Dana Dawson, Michael P Frenneaux
Comparative analysis of cancer vaccine settings for the selection of an effective protocol in mice
Francesca Kalli, Rodolfo Machiorlatti, Florinda Battaglia, Alessia Parodi, Giuseppina Conteduca, Francesca Ferrera, Michele Proietti, Samuele Tardito, Marina Sanguineti, Enrico Millo, Daniela Fenoglio, Raffaele De Palma, Giorgio Inghirami, Gilberto Filaci
Genome scan study of prostate cancer in Arabs: identification of three genomic regions with multiple prostate cancer susceptibility loci in Tunisians
Jingxuan Shan, Khalid Al-Rumaihi, Danny Rabah, Issam Al-Bozom, Dhanya Kizhakayil, Karim Farhat, Sami Al-Said, Hala Kfoury, Shoba P Dsouza, Jillian Rowe, Hanif G Khalak, Shahzad Jafri, Idil I Aigha, Lotfi Chouchane
Origin of the vasculature supporting growth of primary patient tumor xenografts
Bonnie L Hylander, Natalie Punt, Haikuo Tang, Joanna Hillman, Mary Vaughan, Wiam Bshara, Rose Pitoniak, Elizabeth A Repasky
PEP-1-CAT protects hypoxia/reoxygenation-induced cardiomyocyte apoptosis through multiple sigaling pathways
Lei Zhang, Shuang Wei, Jun-Ming Tang, Ling-Yun Guo, Fei Zheng, Jian-Ye Yang, Xia Kong, Yong-Zhang Huang, Shi-You Chen, Jia-Ning Wang
Stromal cell derived factor-1alpha protects stem cell derived insulin-producing cells from glucotoxicity under high glucose conditions in-vitro and ameliorates drug induced diabetes in rats
Muhammad Tariq, Muhammad Sharif Masoud, Azra Mehmood, Shaheen N Khan, Sheikh Riazuddin
HCV Envelope protein 2 sequence comparison of Pakistani isolate and In-silico prediction of conserved epitopes for vaccine development
Sobia Idrees, Usman A Ashfaq, Saba Khaliq
The engagement of CTLA-4 on primary melanoma cell lines induces antibody-dependent cellular cytotoxicity and TNF-α production
Stefania Laurent, Paola Queirolo, Silvia Boero, Sandra Salvi, Patrizia Piccioli, Simona Boccardo, Simona Minghelli, Anna Morabito, Vincenzo Fontana, Gabriella Pietra, Paolo Carrega, Nicoletta Ferrari, Francesca Tosetti, Lung-Ji Chang, Maria Cristina Mingari, Guido Ferlazzo, Alessandro Poggi, Maria Pia Pistillo
Immunohistochemical analysis of the expression of MAGE-A and NY-ESO-1 cancer/testis antigens in diffuse large B-cell testicular lymphoma
Tvrtko Hudolin, Zeljko Kastelan, Ivana Ilic, Katarina Levarda-Hudolin, Nikolina Basic-Jukic, Malte Rieken, Giulio C Spagnoli, Antonio Juretic, Chantal Mengus
Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer
Lijun Yang, Benjamin T Kress, Harris J Weber, Meenakshisundaram Thiyagarajan, Baozhi Wang, Rashid Deane, Helene Benveniste, Jeffrey J Iliff, Maiken Nedergaard
Low expression of LOC285194 is associated with poor prognosis in colorectal cancer
Peng Qi, Mi-die Xu, Shu-juan Ni, Dan Huang, Ping Wei, Cong Tan, Xiao-yan Zhou, Xiang Du
Gadd45a levels in human breast cancer are hormone receptor dependent
Jennifer S Tront, Alliric Willis, Yajue Huang, Barbara Hoffman, Dan A Liebermann
Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer
Satoshi Wada, Christopher M Jackson, Kiyoshi Yoshimura, Hung-Rong Yen, Derese Getnet, Timothy J Harris, Monica V Goldberg, Tullia C Bruno, Joseph F Grosso, Nicholas Durham, George J Netto, Drew M Pardoll, Charles G Drake
Use of V(D)J recombination excision circles to identify T- and B-cell defects and to monitor the treatment in primary and acquired immunodeficiencies
Federico Serana, Marco Chiarini, Cinzia Zanotti, Alessandra Sottini, Diego Bertoli, Andrea Bosio, Luigi Caimi, Luisa Imberti
Identifying translational science within the triangle of biomedicine
Griffin M Weber
Role of warm ischemia on innate and adaptive responses in a preclinical renal auto-transplanted porcine model
Ludivine Rossard, Frédéric Favreau, Sebastien Giraud, Raphael Thuillier, Sylvain Le Pape, Jean Michel Goujon, Alexandre Valagier, Thierry Hauet
A proteomic view of isoproterenol induced cardiac hypertrophy: Prohibitin identified as a potential biomarker in rats
Debabrata Chowdhury, Anjana Devi Tangutur, Tarak Nath Khatua, Priyanka Saxena, Sanjay K Banerjee, Manika Pal Bhadra
Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance
Jennifer Pasquier, Bella S Guerrouahen, Hamda Al Thawadi, Pegah Ghiabi, Mahtab Maleki, Nadine Abu-Kaoud, Arthur Jacob, Massoud Mirshahi, Ludovic Galas, Shahin Rafii, Frank Le Foll, Arash Rafii
Molecular mechanisms of anti-tumor properties of P276-00 in head and neck squamous cell carcinoma
Prabha B Mishra, Aurelio S Lobo, Kalpana S Joshi, Maggie J Rathos, Gopinath A Kumar, Muralidhara Padigaru
Pattern of activation of human antigen presenting cells by genotype GII.4 norovirus virus-like particles
Eleonora Ponterio, Annacarmen Petrizzo, Ilaria Di Bartolo, Franco Maria Buonaguro, Luigi Buonaguro, Franco Maria Ruggeri
Treatment of diabetic nephropathy with Tripterygium wilfordii Hook F extract: a prospective, randomized, controlled clinical trial
Yongchun Ge, Honglang Xie, Shijun Li, Bo Jin, Jinhua Hou, Haitao Zhang, Mingjun Shi, Zhihong Liu
Neuromimetic model of saccades for localizing deficits in an atypical eye-movement pathology
Pierre M Daye, Lance M Optican, Emmanuel Roze, Bertrand Gaymard, Pierre Pouget
A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines
Paulina García-González, Rodrigo Morales, Lorena Hoyos, Jaxaira Maggi, Javier Campos, Bárbara Pesce, David Gárate, Milton Larrondo, Rodrigo González, Lilian Soto, Verónica Ramos, Pía Tobar, María Carmen Molina, Karina Pino-Lagos, Diego Catalán, Juan Carlos Aguillón
Mild therapeutic hypothermia is superior to controlled normothermia for the maintenance of blood pressure and cerebral oxygenation, prevention of organ damage and suppression of oxidative stress after cardiac arrest in a porcine model
Petr Ostadal, Mikulas Mlcek, Andreas Kruger, Svatava Horakova, Marcela Skabradova, Frantisek Holy, Tomas Svoboda, Jan Belohlavek, Vladimir Hrachovina, Ludek Taborsky, Vlasta Dudkova, Hana Psotova, Otomar Kittnar, Petr Neuzil
Autologous fat transfer with in-situ mediation (AIM): a novel and compliant method of adult mesenchymal stem cell therapy
Allan Y Wu, David M Morrow
Transplantation of modified human adipose derived stromal cells expressing VEGF165 results in more efficient angiogenic response in ischemic skeletal muscle
Evgeny K Shevchenko, Pavel I Makarevich, Zoya I Tsokolaeva, Maria A Boldyreva, Veronika Yu Sysoeva, Vsevolod A Tkachuk, Yelena V Parfyonova
Retraction Note: Opportunities and challenges of disease biomarkers: a new section in the journal of translational medicine
Xiangdong Wang, Peter A Ward
Molecular signature of adipose tissue in patients with both Non-Alcoholic Fatty Liver Disease (NAFLD) and Polycystic Ovarian Syndrome (PCOS)
Ancha Baranova, Thuy Phuong Tran, Arian Afendy, Lei Wang, Amirhossein Shamsaddini, Rohini Mehta, Vikas Chandhoke, Aybike Birerdinc, Zobair M Younossi
Future perspectives in melanoma research. Meeting report from the “Melanoma Bridge. Napoli, December 2nd-4th 2012”
Paolo A Ascierto, Antonio M Grimaldi, Nicolas Acquavella, Lorenzo Borgognoni, Luana Calabrò, Natale Cascinelli, Alessandra Cesano, Michele Del Vecchio, Alexander M Eggermont, Mark Faries, Soldano Ferrone, Bernard A Fox, Thomas F Gajewski, Jérôme Galon, Sacha Gnjatic, Helen Gogas, Mohammed Kashani-Sabet, Howard L Kaufman, James Larkin, Roger S Lo, Alberto Mantovani, Kim Margolin, Cornelis Melief, Grant McArthur, Giuseppe Palmieri, Igor Puzanov, Antoni Ribas, Barbara Seliger, Jeff Sosman, Peter Suenaert, Ahmad A Tarhini, Giorgio Trinchieri, Fernando Vidal-Vanaclocha, Ena Wang, Gennaro Ciliberto, Nicola Mozzillo, Francesco M Marincola, Magdalena Thurin
Immunity of human epithelial ovarian carcinoma: the paradigm of immune suppression in cancer
Vincent Lavoué, Aurélie Thédrez, Jean Levêque, Fabrice Foucher, Sébastien Henno, Vincent Jauffret, Marc-Antoine Belaud-Rotureau, Veronique Catros, Florian Cabillic
Protein tyrosine kinase 6 is associated with nasopharyngeal carcinoma poor prognosis and metastasis
Li-na Liu, Pei-yu Huang, Zhi-rui Lin, Li-juan Hu, Jian-zhong Liang, Man-zhi Li, Lin-quan Tang, Mu-sheng Zeng, Qian Zhong, Bo-hang Zeng
Id1 enhances human ovarian cancer endothelial progenitor cell angiogenesis via PI3K/Akt and NF-κB/MMP-2 signaling pathways
Yajuan Su, Lingjuan Gao, Lichen Teng, Ying Wang, Jialin Cui, Shiyun Peng, Songbin Fu
A double blind randomized placebo controlled phase I/II study assessing the safety and efficacy of allogeneic bone marrow derived mesenchymal stem cell in critical limb ischemia
Pawan K Gupta, Anoop Chullikana, Rajiv Parakh, Sanjay Desai, Anjan Das, Sanjay Gottipamula, Sagar Krishnamurthy, Naveen Anthony, Arun Pherwani, Anish S Majumdar
Cellular immunotherapy for refractory hematological malignancies
John L Reagan, Loren D Fast, Howard Safran, Martha Nevola, Eric S Winer, Jorge J Castillo, James N Butera, Matthew I Quesenberry, Carolyn T Young, Peter J Quesenberry
CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer
Wen-jing Wu, Kai-shun Hu, De-shen Wang, Zhao-lei Zeng, Dong-sheng Zhang, Dong-liang Chen, Long Bai, Rui-hua Xu
Impact of anti-CD25 monoclonal antibody on dendritic cell-tumor fusion vaccine efficacy in a murine melanoma model
Chunrui Tan, Varun Reddy, Jens Dannull, Enyu Ding, Smita K Nair, Douglas S Tyler, Scott K Pruitt, Walter T Lee
Combined features based on MT1-MMP expression, CD11b + immunocytes density and LNR predict clinical outcomes of gastric cancer
Chun-Wei Peng, Lin-Wei Wang, Min Fang, Gui-Fang Yang, Yan Li, Dai-Wen Pang
A Phase I vaccine trial using dendritic cells pulsed with autologous oxidized lysate for recurrent ovarian cancer
Lana E Kandalaft, Cheryl L Chiang, Janos Tanyi, Greg Motz, Klara Balint, Rosemarie Mick, George Coukos
The altered expression profile of microRNAs in cardiopulmonary bypass canine models and the effects of mir-499 on myocardial ischemic reperfusion injury
Han Qin, Guang-xian Chen, Meng-ya Liang, Jian Rong, Jian-ping Yao, Hai Liu, Zhong-kai Wu
Exploring dendritic cell based vaccines targeting survivin for the treatment of head and neck cancer patients
Annelies W Turksma, Hetty J Bontkes, Janneke J Ruizendaal, Kirsten BJ Scholten, Johanneke Akershoek, Shakila Rampersad, Laura M Moesbergen, Saskia AGM Cillessen, Saskia JAM Santegoets, Tanja D de Gruijl, C René Leemans, Chris JLM Meijer, Erik Hooijberg
Low-dose temozolomide before dendritic-cell vaccination reduces (specifically) CD4+CD25++Foxp3+ regulatory T-cells in advanced melanoma patients
Laura Ridolfi, Massimiliano Petrini, Anna Maria Granato, Giusy Gentilcore, Ester Simeone, Paolo Antonio Ascierto, Elena Pancisi, Valentina Ancarani, Laura Fiammenghi, Massimo Guidoboni, Francesco de Rosa, Linda Valmorri, Emanuela Scarpi, Stefania Vittoria Luisa Nicoletti, Stefano Baravelli, Angela Riccobon, Ruggero Ridolfi
A multi-site feasibility study for personalized medicine in canines with Osteosarcoma
Noel R Monks, David M Cherba, Steven G Kamerling, Heather Simpson, Anthony W Rusk, Derrick Carter, Emily Eugster, Marie Mooney, Robert Sigler, Matthew Steensma, Tessa Grabinski, Keith R Marotti, Craig P Webb
Immunotherapy with FBTA05 (Bi20), a trifunctional bispecific anti-CD3 x anti-CD20 antibody and donor lymphocyte infusion (DLI) in relapsed or refractory B-cell lymphoma after allogeneic stem cell transplantation: study protocol of an investigator-driven, open-label, non-randomized, uncontrolled, dose-escalating Phase I/II-trial
Raymund Buhmann, Stanglmaier Michael, Hess Juergen, Lindhofer Horst, Christian Peschel, Hans-Jochem Kolb
Dexmedetomidine protects against renal ischemia and reperfusion injury by inhibiting the JAK/STAT signaling activation
Yanna Si, Hongguang Bao, Liu Han, Hongwei Shi, Yuan Zhang, Li Xu, Chenhui Liu, Jinsong Wang, Xiaobing Yang, Akbar Vohra, Daqing Ma
Complementary serum proteomic analysis of autoimmune hepatitis in mice and patients
Hongbin Li, Guoshun Li, Xinyu Zhao, Yongkang Wu, Wen Ma, Yuling Liu, Fengming Gong, Shufang Liang
Role of MUC20 overexpression as a predictor of recurrence and poor outcome in colorectal cancer
Xiuying Xiao, Lisha Wang, Ping Wei, Yayun Chi, Dali Li, Qifeng Wang, Shujuan Ni, Cong Tan, Weiqi Sheng, Menghong Sun, Xiaoyan Zhou, Xiang Du
CARbon DIoxide for the treatment of Febrile seizures: rationale, feasibility, and design of the CARDIF-study
Stephanie Ohlraun, Tobias Wollersheim, Claudia Weiß, Peter Martus, Steffen Weber-Carstens, Dietmar Schmitz, Markus Schuelke
Nuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer
Xi-Qing Li, Xing-Long Yang, Gong Zhang, Si-Pei Wu, Xu-Bing Deng, Sheng-Jun Xiao, Qiu-Zhen Liu, Kai-Tai Yao, Guang-Hui Xiao
Vaccinia virus expressing bone morphogenetic protein-4 in novel glioblastoma orthotopic models facilitates enhanced tumor regression and long-term survival
Rohit Duggal, Ulrike Geissinger, Qian Zhang, Jason Aguilar, Nanhai G Chen, Elena Binda, Angelo L Vescovi, Aladar A Szalay
Secretoglobin expression in ovarian carcinoma: lipophilin B gene upregulation as an independent marker of better prognosis
Eliana Bignotti, Renata A Tassi, Stefano Calza, Antonella Ravaggi, Elisa Rossi, Carla Donzelli, Paola Todeschini, Chiara Romani, Elisabetta Bandiera, Laura Zanotti, Mario Carnazza, Francesco Quadraro, Germana Tognon, Enrico Sartori, Sergio Pecorelli, Dana M Roque, Alessandro D Santin
Genetic mutations of GJB2 and mitochondrial 12S rRNA in nonsyndromic hearing loss in Jiangsu Province of China
Qinjun Wei, Shuai Wang, Jun Yao, Yajie Lu, Zhibin Chen, Guangqian Xing, Xin Cao
Effects of hepatocyte nuclear factor-1A and -4A on pancreatic stone protein/regenerating protein and C-reactive protein gene expression: implications for maturity-onset diabetes of the young
Ma P Kyithar, Caroline Bonner, Siobhan Bacon, Seán M Kilbride, Jasmin Schmid, Rolf Graf, Jochen HM Prehn, Maria M Byrne
Fat utilization and arterial hypertension in overweight/obese subjects
Yvelise Ferro, Carmine Gazzaruso, Adriana Coppola, Stefano Romeo, Valeria Migliaccio, Andrea Giustina, Arturo Pujia, Tiziana Montalcini
Langerhans-type and monocyte-derived human dendritic cells have different susceptibilities to mRNA electroporation with distinct effects on maturation and activation: implications for immunogenicity in dendritic cell-based immunotherapy
David J Chung, Emanuela Romano, Katherine B Pronschinske, Justin A Shyer, Milena Mennecozzi, Erin T St Angelo, James W Young
Induction of an EMT-like transformation and MET in vitro
Songming Ding, Wu Zhang, Zhiyuan Xu, Chunyang Xing, Haiyang Xie, Haijun Guo, Kanjie Chen, Penghong Song, Yu Gu, Fengqiang Xiao, Lin Zhou, Shusen Zheng
Establishment of patient-derived non-small cell lung cancer xenograft models with genetic aberrations within EGFR, KRAS and FGFR1: useful tools for preclinical studies of targeted therapies
Xu-chao Zhang, Jingchuan Zhang, Ming Li, Xiao-sui Huang, Xue-ning Yang, Wen-zhao Zhong, Liang Xie, Lin Zhang, Minhua Zhou, Paul Gavine, Xinying Su, Li Zheng, Guanshan Zhu, Ping Zhan, Qunsheng Ji, Yi-long Wu
Importance of leptin signaling and signal transducer and activator of transcription-3 activation in mediating the cardiac hypertrophy associated with obesity
Maren Leifheit-Nestler, Nana-Maria Wagner, Rajinikanth Gogiraju, Michael Didié, Stavros Konstantinides, Gerd Hasenfuss, Katrin Schäfer
Cytosolic phosphorylated EGFR is predictive of recurrence in early stage penile cancer patients: a retropective study
Giuseppe Di Lorenzo, Sisto Perdonà, Carlo Buonerba, Guru Sonpavde, Vincenzo Gigantino, Giuseppe Pannone, Giuseppe Quarto, Matteo Ferro, Gabriella Gaudioso, Daniela Terracciano, Rossella Di Trolio, Pasquale Rescigno, Gerardo Botti, Sabino De Placido, Gaetano Facchini, Paolo A Ascierto, Renato Franco
Intracavernous administration of bone marrow mononuclear cells: a new method of treating erectile dysfunction?
Thomas E Ichim, Timothy Warbington, Octav Cristea, Joseph L Chin, Amit N Patel
A prospective, non-randomized, no placebo-controlled, phase Ib clinical trial to study the safety of the adipose derived stromal cells-stromal vascular fraction in idiopathic pulmonary fibrosis
Argyris Tzouvelekis, Vassilis Paspaliaris, George Koliakos, Paschalis Ntolios, Evangelos Bouros, Anastasia Oikonomou, Athanassios Zissimopoulos, Nikolaos Boussios, Brian Dardzinski, Dimitrios Gritzalis, Antonis Antoniadis, Marios Froudarakis, George Kolios, Demosthenes Bouros
Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor
Mohit K Verma, Yasuhiro Miki, Keiko Abe, Takashi Suzuki, Hiromichi Niikawa, Satoshi Suzuki, Takashi Kondo, Hironobu Sasano
Betaine supplement enhances skeletal muscle differentiation in murine myoblasts via IGF-1 signaling activation
Pamela Senesi, Livio Luzi, Anna Montesano, Nausicaa Mazzocchi, Ileana Terruzzi
Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies
Luigi Fattore, Emanuele Marra, Maria Elena Pisanu, Alessia Noto, Claudia de Vitis, Francesca Belleudi, Luigi Aurisicchio, Rita Mancini, Maria Rosaria Torrisi, Paolo Antonio Ascierto, Gennaro Ciliberto
Characterization of humoral responses to soluble trimeric HIV gp140 from a clade A Ugandan field isolate
Maria Luisa Visciano, Maria Tagliamonte, Guillaume Stewart-Jones, Leo Heyndrickx, Guido Vanham, Marianne Jansson, Anders Fomsgaard, Berit Grevstad, Meghna Ramaswamy, Franco M Buonaguro, Maria Lina Tornesello, Priscilla Biswas, Gabriella Scarlatti, Luigi Buonaguro
Nephrolithiasis: nutrition as cause or therapeutic tool
Irene Brenna, Elena Dogliotti, Annalisa Terranegra, Benedetta Raspini, Laura Soldati
Vitamin d deficiency impacts on expression of toll-like receptor-2 and cytokine profile: a pilot study
Samar Ojaimi, Narelle A Skinner, Boyd JG Strauss, Vijaya Sundararajan, Ian Woolley, Kumar Visvanathan
A network model of genomic hormone interactions underlying dementia and its translational validation through serendipitous off-target effect
Erfan Younesi, Martin Hofmann-Apitius
Safe temperature range for intraoperative and early postoperative continuous hyperthermic intraperitoneal perfusion in a swine model of experimental distal gastrectomy with Billroth II reconstruction
Sheng Li, Yong-lei Zhang, Jia-yuan Sun, Ya-wei Hua, Pei-hong Wu
Autologous transplantation of adipose-derived stromal cells ameliorates ventilator-induced lung injury in rats
Zuo Di Liang, Xiu Ru Yin, Da Sheng Cai, Heng Zhou, Ling Pei
MiRNA-329 targeting E2F1 inhibits cell proliferation in glioma cells
Bingxiang Xiao, Li Tan, Benfu He, Zhiliang Liu, Ruxiang Xu
Metallothionein 2A inhibits NF-κB pathway activation and predicts clinical outcome segregated with TNM stage in gastric cancer patients following radical resection
Yuanming Pan, Jiaqiang Huang, Rui Xing, Xin Yin, Jiantao Cui, Wenmei Li, Jun Yu, Youyong Lu
Intravenous administration of mesenchymal stem cells prevents angiotensin II-induced aortic aneurysm formation in apolipoprotein E-deficient mouse
Xian-ming Fu, Aika Yamawaki-Ogata, Hideki Oshima, Yuichi Ueda, Akihiko Usui, Yuji Narita
Identification of prefoldin amplification (1q23.3-q24.1) in bladder cancer using comparative genomic hybridization (CGH) arrays of urinary DNA
Virginia López, Pilar González-Peramato, Javier Suela, Alvaro Serrano, Ferrán Algaba, Juan C Cigudosa, August Vidal, Joaquim Bellmunt, Oscar Heredero, Marta Sánchez-Carbayo
Integrated wall stress: a new methodological approach to assess ventricular workload and myocardial contractile reserve
Hailong Dong, Heather Mosca, Erhe Gao, Robert E Akins, Samuel S Gidding, Takeshi Tsuda
Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry
Bo Wook Kim, Hanbyoul Cho, Joon-Yong Chung, Catherine Conway, Kris Ylaya, Jae-Hoon Kim, Stephen M Hewitt
Assessment of risk of bias in translational science
Andre Barkhordarian, Peter Pellionisz, Mona Dousti, Vivian Lam, Lauren Gleason, Mahsa Dousti, Josemar Moura, Francesco Chiappelli
Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells
Petra C Schuberth, Christian Hagedorn, Shawn M Jensen, Pratiksha Gulati, Maries van den Broek, Axel Mischo, Alex Soltermann, Astrid Jüngel, Osiris Marroquin Belaunzaran, Rolf Stahel, Christoph Renner, Ulf Petrausch
Impact of baseline and nadir neutrophil index in non-small cell lung cancer and ovarian cancer patients: Assessment of chemotherapy for resolution of unfavourable neutrophilia
Andreas Carus, Howard Gurney, Val Gebski, Paul Harnett, Rina Hui, Richard Kefford, Nicholas Wilcken, Morten Ladekarl, Hans von der Maase, Frede Donskov
Clinical experience with intravenous administration of ascorbic acid: achievable levels in blood for different states of inflammation and disease in cancer patients
Nina Mikirova, Joseph Casciari, Neil Riordan, Ronald Hunninghake
Utilization of TREC and KREC quantification for the monitoring of early T- and B-cell neogenesis in adult patients after allogeneic hematopoietic stem cell transplantation
Angela Mensen, Christoph Ochs, Andrea Stroux, Friedrich Wittenbecher, Martin Szyska, Luisa Imberti, Simon Fillatreau, Lutz Uharek, Renate Arnold, Bernd Dörken, Andreas Thiel, Carmen Scheibenbogen, Il-Kang Na
Validation of analytical methods in compliance with good manufacturing practice: a practical approach
Deborah Rustichelli, Sara Castiglia, Monica Gunetti, Katia Mareschi, Elena Signorino, Michela Muraro, Laura Castello, Fiorella Sanavio, Marco Leone, Ivana Ferrero, Franca Fagioli
Flotillin-2 is associated with breast cancer progression and poor survival outcomes
Xi Wang, Qi Yang, Ling Guo, Xing-Hua Li, Xiao-Hui Zhao, Li-Bing Song, Huan-Xin Lin
Targeting therapy of hepatocellular carcinoma with doxorubicin prodrug PDOX increases anti-metastatic effect and reduces toxicity: a preclinical study
Qun Wang, Yan-Jun Zhong, Jing-Ping Yuan, Li-Hua Shao, Jue Zhang, Li Tang, Shao-Ping Liu, Ya-Ping Hong, Raymond A Firestone, Yan Li
Fc-gamma receptor polymorphisms as predictive and prognostic factors in patients receiving oncolytic adenovirus treatment
Mari Hirvinen, Raita Heiskanen, Minna Oksanen, Saila Pesonen, Ilkka Liikanen, Timo Joensuu, Anna Kanerva, Vincenzo Cerullo, Akseli Hemminki
Transplantation of human cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells in autism
Yong-Tao Lv, Yun Zhang, Min Liu, Jia-na-ti Qiuwaxi, Paul Ashwood, Sungho Charles Cho, Ying Huan, Ru-Cun Ge, Xing-Wang Chen, Zhao-Jing Wang, Byung-Jo Kim, Xiang Hu
The clinical utility of bone marker measurements in osteoporosis
Gillian Wheater, Mohsen Elshahaly, Stephen P Tuck, Harish K Datta, Jacob M van Laar
Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma
Maria Colombino, Amelia Lissia, Mariaelena Capone, Vincenzo De Giorgi, Daniela Massi, Ignazio Stanganelli, Ester Fonsatti, Michele Maio, Gerardo Botti, Corrado Caracò, Nicola Mozzillo, Paolo A Ascierto, Antonio Cossu, Giuseppe Palmieri
The independent, unfavorable prognostic factors endothelin A receptor and chemokine receptor 4 have a close relationship in promoting the motility of nasopharyngeal carcinoma cells via the activation of AKT and MAPK pathways
Dong-Hua Luo, Qiu-Yan Chen, Huai Liu, Li-Hua Xu, Hui-Zhong Zhang, Lu Zhang, Lin-Quan Tang, Hao-Yuan Mo, Pei-Yu Huang, Xiang Guo, Hai-Qiang Mai
Forkhead box transcription factor 1 expression in gastric cancer: FOXM1 is a poor prognostic factor and mediates resistance to docetaxel
Xiaoxiao Li, Wensheng Qiu, Bin Liu, Ruyong Yao, Shihai Liu, Yasai Yao, Jun Liang
Patient-derived tissue slice grafts accurately depict response of high-risk primary prostate cancer to androgen deprivation therapy
Hongjuan Zhao, Alan Thong, Rosalie Nolley, Stephen W Reese, Jennifer Santos, Alexandre Ingels, Donna M Peehl
Vitamin D deficiency and prognostics among patients with pancreatic adenocarcinoma
May Cho, Parvin F Peddi, Kevin Ding, Ling Chen, Denise Thomas, Jian Wang, Albert C Lockhart, Benjamin Tan, Andrea Wang-Gillam
Inactivated Sendai virus strain Tianjin, a novel genotype of Sendai virus, inhibits growth of murine colon carcinoma through inducing immune responses and apoptosis
Liying Shi, Jun Chen, Qiping Zhong, Mei Li, Peng Geng, Jianmin He, Zhe Han, Mingwei Sheng, Hua Tang
MicroRNA-503 inhibits the G1/S transition by downregulating cyclin D3 and E2F3 in hepatocellular carcinoma
Fenqiang Xiao, Wu zhang, Liming Chen, Fei Chen, Haiyang Xie, Chunyang Xing, Xiaobo Yu, Songming Ding, Kangjie Chen, Haijun Guo, Jun Cheng, Shusen Zheng, Lin Zhou
Exploring smooth muscle phenotype and function in a bioreactor model of abdominal aortic aneurysm
Kirsten Riches, Timothy G Angelini, Gurprit S Mudhar, Jean Kaye, Emily Clark, Marc A Bailey, Soroush Sohrabi, Sotirios Korossis, Peter G Walker, D Julian A Scott, Karen E Porter
Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma
Qing-Feng Zou, Ji-Ke Du, Hua Zhang, Hong-Bo Wang, Ze-Dong Hu, Shu-Peng Chen, Yong Du, Man-Zhi Li, Dan Xie, Juan Zou, Han-Dong Sun, Jian-Xin Pu, Mu-Sheng Zeng
Upregulation of M3 muscarinic receptor inhibits cardiac hypertrophy induced by angiotensin II
Yan Liu, Shu Wang, Chao Wang, Haoxin Song, Hongmei Han, Pengzhou Hang, Yanan Jiang, Lanlan Wei, Rong Huo, Lihua Sun, Xu Gao, Yanjie Lu, Zhimin Du
Molecular-guided therapy predictions reveal drug resistance phenotypes and treatment alternatives in malignant peripheral nerve sheath tumors
Jacqueline D Peacock, David Cherba, Kevin Kampfschulte, Mallory K Smith, Noel R Monks, Craig P Webb, Matthew Steensma
Are morphological criteria sufficient for the identification of circulating tumor cells in renal cancer?
Amin El-Heliebi, Thomas Kroneis, Evelyn Zöhrer, Johannes Haybaeck, Katja Fischereder, Karin Kampel-Kettner, Richard Zigeuner, Hannelore Pock, Regina Riedl, Rudolf Stauber, Jochen Bernd Geigl, Berthold Huppertz, Peter Sedlmayr, Carolin Lackner
VEGF-A isoform modulation in an preclinical TNBS model of ulcerative colitis: protective effects of a VEGF164b therapy
Walter E Cromer, Chaitanya V Ganta, Mihir Patel, James Traylor, Christopher G Kevil, J Steven Alexander, J Michael Mathis
Innate immunity activation involved in unprotected porcine auto-transplant kidneys preserved by naked caspase-3 siRNA
Cheng Yang, Long Li, Yinjia Xue, Zitong Zhao, Tian Zhao, Yichen Jia, Ruiming Rong, Ming Xu, Michael L Nicholson, Tongyu Zhu, Bin Yang
rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ
Jagadeesh K Venkatesan, Ana Rey-Rico, Gertrud Schmitt, Anna Wezel, Henning Madry, Magali Cucchiarini
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells
Klaus Mantwill, Ulrike Naumann, Janina Seznec, Vroni Girbinger, Hermann Lage, Pawel Surowiak, Dagmar Beier, Michel Mittelbronn, Jürgen Schlegel, Per Sonne Holm
Genetic variance in Nitric Oxide Synthase and Endothelin Genes among children with and without Endothelial Dysfunction
Siriporn Chatsuriyawong, David Gozal, Leila Kheirandish-Gozal, Rakesh Bhattacharjee, Ahamed A Khalyfa, Yang Wang, Hakon Hakonarson, Brendan Keating, Wasana Sukhumsirichart, Abdelnaby Khalyfa
Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers
Shaohua Peng, Chad J Creighton, Yiqun Zhang, Banibrata Sen, Tuhina Mazumdar, Jeffery N Myers, Adrian Woolfson, Matthew V Lorenzi, Diana Bell, Michelle D Williams, Faye M Johnson
Plasma microRNA-133a is a new marker for both acute myocardial infarction and underlying coronary artery stenosis
Feng Wang, Guangwen Long, Chunxia Zhao, Huaping Li, Sandip Chaugai, Yan Wang, Chen Chen, Dao Wen Wang
Different amounts of protein-bound citrulline and homocitrulline in foot joint tissues of a patient with anti-citrullinated protein antibody positive erosive rheumatoid arthritis
Sanna Turunen, Marja-Kaisa Koivula, Jukka Melkko, Eeva Alasaarela, Petri Lehenkari, Juha Risteli
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Haojun Song, Weiliang Sun, Guoliang Ye, Xiaoyun Ding, Zhong Liu, Sijie Zhang, Tian Xia, Bingxiu Xiao, Yang Xi, Junming Guo
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Nathalie Accart, Mirjana Urosevic-Maiwald, Reinhard Dummer, Vincent Bataille, Nadine Kehrer, Cristina Niculescu, Jean-Marc Limacher, Marie-Pierre Chenard, Jean-Yves Bonnefoy, Ronald Rooke
Increased resistin in brain dead organ donors is associated with delayed graft function after kidney transplantation
Simona Oltean, Rille Pullerits, Anne Flodén, Michael Olausson, Mihai Oltean
Increased long-term expression of pentraxin 3 in irradiated human arteries and veins compared to internal controls from free tissue transfers
Tinna Christersdottir Björklund, Sarah-Jayne Reilly, Caroline Gahm, Barbara Bottazzi, Alberto Mantovani, Per Tornvall, Martin Halle
Downregulation of KPNA2 in non-small-cell lung cancer is associated with Oct4 expression
Xiao-Lei Li, Lan-Ling Jia, Mu-Mu Shi, Xin Li, Zhong-Hua Li, Hui-Feng Li, En-Hua Wang, Xin-Shan Jia
Enhanced interaction between natural killer cells and lung cancer cells: involvement in gefitinib-mediated immunoregulation
Sisi He, Tao Yin, Dan Li, Xiang Gao, Yang Wan, Xuelei Ma, Tinghong Ye, Fuchun Guo, Jianhong Sun, Ziqiang Lin, Yongsheng Wang
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Jônatas Caldeira Esteves, Elcio Marcantonio Jr, Ana Paula de Souza Faloni, Fernanda Regina Godoy Rocha, Rosemary Adriana Marcantonio, Katarzyna Wilk, Giuseppe Intini
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Dustin J Weiss, George P Casale, Panagiotis Koutakis, Aikaterini A Nella, Stanley A Swanson, Zhen Zhu, Dimitrios Miserlis, Jason M Johanning, Iraklis I Pipinos
Low-dose azathioprine is effective in maintaining remission among Chinese patients with Crohn’s disease
Jianghong Wu, Yan Gao, Chuanhua Yang, Xueqing Yang, Xuhang Li, Shudong Xiao
Structured myeloid cells and anti-angiogenic therapy in alveolar soft part sarcoma
Chiara Castelli, Marcella Tazzari, Tiziana Negri, Barbara Vergani, Licia Rivoltini, Silvia Stacchiotti, Silvana Pilotti
Impact of heart failure on the behavior of human neonatal stem cells in vitro
Kristin Klose, Rajika Roy, Andreja Brodarac, Andreas Kurtz, Andrea Ode, Kyung-Sun Kang, Karen Bieback, Yeong-Hoon Choi, Christof Stamm
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Federica Ciregia, Laura Giusti, Ylenia Da Valle, Elena Donadio, Arianna Consensi, Camillo Giacomelli, Francesca Sernissi, Pietro Scarpellini, Fabrizio Maggi, Antonio Lucacchini, Laura Bazzichi
Lentiviral-mediated RNA interference targeting stathmin1 gene in human gastric cancer cells inhibits proliferation in vitro and tumor growth in vivo
Javed Akhtar, Zhou Wang, Zhi Ping Zhang, Ming Ming Bi
Over-expression of the special AT rich sequence binding protein 1 (SATB1) promotes the progression of nasopharyngeal carcinoma: association with EBV LMP-1 expression
Zhihua Shen, Yumei Zeng, Junli Guo, Yanxia Wu, Xiaofan Jiang, Ranran Ding, Changli Wu, Rujia Li, Botao Luo, Chao Zeng, Hanguo Jiang, Wei Jie
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Dario Marangoni, Benedetto Falsini, Marco Piccardi, Lucia Ambrosio, Angelo Maria Minnella, Maria Cristina Savastano, Silvia Bisti, Rita Maccarone, Antonello Fadda, Enrica Mello, Paola Concolino, Ettore Capoluongo
Quantitative proteomic analysis in HCV-induced HCC reveals sets of proteins with potential significance for racial disparity
Simon T Dillon, Manoj K Bhasin, Xiaoxing Feng, David W Koh, Sayed S Daoud
The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere
Jing Li, Barry R Davies, Sufang Han, Minhua Zhou, Yu Bai, Jingchuan Zhang, Yan Xu, Lily Tang, Huiying Wang, Yuan Jie Liu, Xiaolu Yin, Qunsheng Ji, De-Hua Yu
CXCR7 expression in esophageal cancer
Michael Tachezy, Hilke Zander, Florian Gebauer, Katharina von Loga, Klaus Pantel, Jakob R Izbicki, Maximilian Bockhorn
Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients
Shinichi Kageyama, Hisashi Wada, Kei Muro, Yasumasa Niwa, Shugo Ueda, Hiroshi Miyata, Shuji Takiguchi, Sahoko H Sugino, Yoshihiro Miyahara, Hiroaki Ikeda, Naoko Imai, Eiichi Sato, Tomomi Yamada, Masaharu Osako, Mami Ohnishi, Naozumi Harada, Tadashi Hishida, Yuichiro Doki, Hiroshi Shiku
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Philipp Stiegler, Michael Sereinigg, Andreas Puntschart, Andrea Bradatsch, Thomas Seifert-Held, Iris Wiederstein-Grasser, Bettina Leber, Elke Stadelmeyer, Nadia Dandachi, Siglinde Zelzer, Florian Iberer, Vanessa Stadlbauer
Multi-nutrient supplement improves hormone ratio associated with cancer risk
Anthony J Bazzan, George P Zabrecky, Andrew B Newberg
Identical effects of VEGF and serum-deprivation on phenotype and function of adipose-derived stromal cells from healthy donors and patients with ischemic heart disease
Bjarke Follin, Josefine Tratwal, Mandana Haack-Sørensen, Jens Jørgen Elberg, Jens Kastrup, Annette Ekblond
PTPRO promoter methylation is predictive of poorer outcome for HER2-positive breast cancer: indication for personalized therapy
Yi-Teng Huang, Fei-Fei Li, Chen Ke, Zhou Li, Zong-Tai Li, Xiao-Fang Zou, Xiao-Xuan Zheng, Yu-Ping Chen, Hao Zhang
Combined TIM-3 blockade and CD137 activation affords the long-term protection in a murine model of ovarian cancer
Zhiqiang Guo, Dali Cheng, Zhijun Xia, Meng Luan, Liangliang Wu, Gang Wang, Shulan Zhang
MicroRNAs induced in melanoma treated with combination targeted therapy of Temsirolimus and Bevacizumab
Aubrey G Wagenseller, Amber Shada, Kevin M D’Auria, Cheryl Murphy, Dandan Sun, Kerrington R Molhoek, Jason A Papin, Anindya Dutta, Craig L Slingluff Jr
HLA-dependent tumour development: a role for tumour associate macrophages?
Maddalena Marchesi, Emilia Andersson, Lisa Villabona, Barbara Seliger, Andreas Lundqvist, Rolf Kiessling, Giuseppe V Masucci
Influence of lean and fat mass on bone mineral density and on urinary stone risk factors in healthy women
Antonio Nouvenne, Andrea Ticinesi, Angela Guerra, Giuseppina Folesani, Franca Allegri, Silvana Pinelli, Paolo Baroni, Mario Pedrazzoni, Giuseppe Lippi, Annalisa Terranegra, Elena Dogliotti, Laura Soldati, Loris Borghi, Tiziana Meschi
Challenges facing translational research organizations in China: a qualitative multiple case study
Laixin Zhou, Ying Li, Hayden B Bosworth, John Ehiri, Changkun Luo
Head and neck irradiation modulates pharmacokinetics of 5-fluorouracil and cisplatin
Chen-Hsi Hsieh, Mei-Ling Hou, Meng-Hsuan Chiang, Hung-Chi Tai, Hui-Ju Tien, Li-Ying Wang, Tung-Hu Tsai, Yu-Jen Chen
Notch signaling activation contributes to cardioprotection provided by ischemic preconditioning and postconditioning
Xue-liang Zhou, Li Wan, Qi-rong Xu, Yong Zhao, Ji-chun Liu
Renal cell neoplasias: reversion-inducing cysteine-rich protein with Kazal motifs discriminates tumor subtypes, while extracellular matrix metalloproteinase inducer indicates prognosis
Anja Rabien, Carsten Stephan, Ergin Kilic, Wilko Weichert, Glen Kristiansen, Kurt Miller, Klaus Jung, Andreas Erbersdobler
The association among leukocyte apoptosis, autoantibodies and disease severity in systemic lupus erythematosus
Yu-Jih Su, Tien-Tsai Cheng, Chung-Jen Chen, Wen-Chan Chiu, Chung-Yuan Hsu, Wen-Neng Chang, Nai-Wen Tsai, Chia-Te Kung, Hung-Chen Wang, Wei-Che Lin, Chih-Cheng Huang, Ya-Ting Chang, Chih-Min Su, Yi-Fang Chiang, Ben-Chung Cheng, Yu-Jun Lin, Cheng-Hsien Lu
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Diana Torres-García, Alfredo Cruz-Lagunas, Ma Cecilia García-Sancho Figueroa, Rosario Fernández-Plata, Renata Baez-Saldaña, Criselda Mendoza-Milla, Rodrigo Barquera, Aida Carrera-Eusebio, Salomón Ramírez-Bravo, Lizeth Campos, Javier Angeles, Gilberto Vargas-Alarcón, Julio Granados, Radha Gopal, Shabaana A Khader, Edmond J Yunis, Joaquin Zuñiga
Antitumor efficacy of a recombinant adenovirus encoding endostatin combined with an E1B55KD-deficient adenovirus in gastric cancer cells
Li-xia Li, Yan-ling Zhang, Ling Zhou, Miao-la Ke, Jie-min Chen, Xiang Fu, Chun-ling Ye, Jiang-xue Wu, Ran-yi Liu, Wenlin Huang
A first-in-human, phase 1, dose-escalation study of dinaciclib, a novel cyclin-dependent kinase inhibitor, administered weekly in subjects with advanced malignancies
John J Nemunaitis, Karen A Small, Paul Kirschmeier, Da Zhang, Yali Zhu, Ying-Ming Jou, Paul Statkevich, Siu-Long Yao, Rajat Bannerji
Secreted proteins from carotid endarterectomy: an untargeted approach to disclose molecular clues of plaque progression
Silvia Rocchiccioli, Gualtiero Pelosi, Silvia Rosini, Michele Marconi, Federica Viglione, Lorenzo Citti, Mauro Ferrari, Maria Giovanna Trivella, Antonella Cecchettini
Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell
Salvatore De Maria, Ilaria Scognamiglio, Angela Lombardi, Nicola Amodio, Michele Caraglia, Maria Cartenì, Gianpietro Ravagnan, Paola Stiuso
Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease
Lee Campbell, Ghaith Al-Jayyoussi, Robert Gutteridge, Nigel Gumbleton, Rosie Griffiths, Simon Gumbleton, Mathew W Smith, David FR Griffiths, Mark Gumbleton
Adipose-derived regenerative cell (ADRC)-enriched fat grafting: optimal cell concentration and effects on grafted fat characteristics
Natsuko Kakudo, Yoshihito Tanaka, Naoki Morimoto, Takeshi Ogawa, Satoshi Kushida, Tomoya Hara, Kenji Kusumoto
IGF-I increases markers of osteoblastic activity and reduces bone resorption via osteoprotegerin and RANK-ligand
Lucia Guerra-Menéndez, Maria C Sádaba, Juan E Puche, Jose L Lavandera, Luis F de Castro, Arancha R de Gortázar, Inma Castilla-Cortázar
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Xiao-li Wei, Miao-zhen Qiu, Wei-wei Chen, Ying Jin, Chao Ren, Feng Wang, Hui-yan Luo, Zhi-qiang Wang, Dong-sheng Zhang, Feng-hua Wang, Yu-hong Li, Rui-hua Xu
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Wen G Jiang, Lin Ye, Andrew J Sanders, Fiona Ruge, Howard G Kynaston, Richard J Ablin, Malcolm D Mason
Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients’ bed
Stefano Ferrari, Francesca Perut, Franca Fagioli, Adalberto Brach Del Prever, Cristina Meazza, Antonina Parafioriti, Piero Picci, Marco Gambarotti, Sofia Avnet, Nicola Baldini, Stefano Fais
LARP1 predict the prognosis for early-stage and AFP-normal hepatocellular carcinoma
Chan Xie, Li Huang, Shibin Xie, Dongying Xie, Genlin Zhang, Peipei Wang, Liang Peng, Zhiliang Gao
Assessing excellence in translational cancer research: a consensus based framework
Abinaya Rajan, Carlos Caldas, Henri van Luenen, Mahasti Saghatchian, Wim H van Harten
Chemically linked phage idiotype vaccination in the murine B cell lymphoma 1 model
Tim Roehnisch, Cornelia Then, Wolfgang Nagel, Christina Blumenthal, Todd Braciak, Mariel Donzeau, Thomas Böhm, Carole Bourquin, Fuat Oduncu
Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals
Stine Buch Thorsen, Martin Lundberg, Andrea Villablanca, Sarah Louise T Christensen, Kirstine Christensen Belling, Birgitte Sander Nielsen, Mick Knowles, Nick Gee, Hans Jørgen Nielsen, Nils Brünner, Ib Jarle Christensen, Simon Fredriksson, Jan Stenvang, Erika Assarsson
Abnormal expression of paxillin correlates with tumor progression and poor survival in patients with gastric cancer
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MicroRNA-124-3p inhibits cell migration and invasion in bladder cancer cells by targeting ROCK1
Xianglai Xu, Shiqi Li, Yiwei Lin, Hong Chen, Zhenghui Hu, Yeqing Mao, Xin Xu, Jian Wu, Yi Zhu, Xiangyi Zheng, Jindan Luo, Liping Xie
Detection of colon polyps by a novel, polymer pattern-based full blood test
Markus Franz, Matthias Scholz, Ilka Henze, Stefan Röckl, Luis I Gomez
Melanoma risk loci as determinants of melanoma recurrence and survival
Justin Rendleman, Shulian Shang, Christine Dominianni, Jerry F Shields, Patrick Scanlon, Christina Adaniel, Alexis Desrichard, Michelle Ma, Richard Shapiro, Russell Berman, Anna Pavlick, David Polsky, Yongzhao Shao, Iman Osman, Tomas Kirchhoff
Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells
Birdal Bilir, Omer Kucuk, Carlos S Moreno
Wound outcome in combat injuries is associated with a unique set of protein biomarkers
Brett A Chromy, Angela Eldridge, Jonathan A Forsberg, Trevor S Brown, Benjamin C Kirkup, Crystal Jaing, Nicholas A Be, Eric Elster, Paul A Luciw
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Salvador Harguindey, Jose Luis Arranz, Julian David Polo Orozco, Cyril Rauch, Stefano Fais, Rosa Angela Cardone, Stephan J Reshkin
The involvement of MMP-2 and MMP-9 in heart exercise-related angiogenesis
Marianna Bellafiore, Giuseppe Battaglia, Antonino Bianco, Felicia Farina, Antonio Palma, Antonio Paoli
Novel compound heterozygous mutations in the MYO15A gene in autosomal recessive hearing loss identified by whole-exome sequencing
Xue Gao, Qing-yan Zhu, Yue-Shuai Song, Guo-Jian Wang, Yong-Yi Yuan, Feng Xin, Sha-Sha Huang, Dong-Yang Kang, Ming-Yu Han, Li-ping Guan, Jian-guo Zhang, Pu Dai
Tumor-dependent increase of serum amino acid levels in breast cancer patients has diagnostic potential and correlates with molecular tumor subtypes
Isabel Poschke, Yumeng Mao, Rolf Kiessling, Jana de Boniface
Association of autoantibodies against the M2-muscarinic receptor with perinatal outcomes in women with severe preeclampsia
Yanfang Li, Guiling Ma, Zhiyong Zhang, Yin Yue, Yuting Yuan, Yidan Wang, Guobin Miao, Lin Zhang
Renoprotective capacities of non-erythropoietic EPO derivative, ARA290, following renal ischemia/reperfusion injury
Willem G van Rijt, Gertrude J Nieuwenhuijs-Moeke, Harry van Goor, Petra J Ottens, Rutger J Ploeg, Henri GD Leuvenink
NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM-2
Todd A Braciak, Sarah Wildenhain, Claudia C Roskopf, Ingo A Schubert, Georg H Fey, Uwe Jacob, Karl-Peter Hopfner, Fuat S Oduncu
Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study
Jenny Brändstedt, Sakarias Wangefjord, Signe Borgquist, Björn Nodin, Jakob Eberhard, Jonas Manjer, Karin Jirström
Everolimus-induced epithelial to mesenchymal transition in immortalized human renal proximal tubular epithelial cells: key role of heparanase
Valentina Masola, Gianluigi Zaza, Simona Granata, Giovanni Gambaro, Maurizio Onisto, Antonio Lupo
Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity
Karin Zins, Sandun Gunawardhana, Trevor Lucas, Dietmar Abraham, Seyedhossein Aharinejad
Insufficient radiofrequency ablation promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells through Akt and ERK signaling pathways
Shuying Dong, Jian Kong, Fandong Kong, Jinge Kong, Jun Gao, Shan Ke, Shaohong Wang, Xuemei Ding, Wenbing Sun, Lemin Zheng
Fusion of Hsp70 to Mage-a1 enhances the potency of vaccine-specific immune responses
Juhong Jiang, Dan Xie, Wenmin Zhang, Gang Xiao, Jianming Wen
The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22
Massimo Pancione, Andrea Remo, Caterina Zanella, Lina Sabatino, Arturo Di Blasi, Carmelo Laudanna, Laura Astati, Michele Rocco, Delfina Bifano, Paolo Piacentini, Laura Pavan, Alberto Purgato, Filippo Greco, Alberto Talamini, Andrea Bonetti, Michele Ceccarelli, Roberto Vendraminelli, Erminia Manfrin, Vittorio Colantuoni
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Piotr Widłak, Monika Pietrowska, Joanna Polańska, Tomasz Rutkowski, Karol Jelonek, Magdalena Kalinowska-Herok, Agnieszka Gdowicz-Kłosok, Andrzej Wygoda, Rafał Tarnawski, Krzysztof Składowski
RETRACTED ARTICLE: Mir-655 up-regulation suppresses cell invasion by targeting pituitary tumor-transforming gene-1 in esophageal squamous cell carcinoma
Yuanyuan Wang, Wenqiao Zang, Yuwen Du, Yunyun Ma, Min Li, Ping Li, Xudong Chen, Tao Wang, Ziming Dong, Guoqiang Zhao
Phase I/II clinical trial using HLA-A24-restricted peptide vaccine derived from KIF20A for patients with advanced pancreatic cancer
Shingo Asahara, Kazuyoshi Takeda, Kenji Yamao, Hiroyuki Maguchi, Hiroki Yamaue
Differential immunomodulatory effects by Tripterygium wilfordii Hook f-derived refined extract PG27 and its purified component PG490 (triptolide) in human peripheral blood T cells: potential therapeutics for arthritis and possible mechanisms explaining in part Chinese herbal theory “Junn-Chenn-Zuou-SS”
Ling-Jun Ho, Wen-Liang Chang, Ann Chen, Ping Chao, Jenn-Haung Lai
Circulating microRNA: a novel potential biomarker for early diagnosis of Intracranial Aneurysm Rupture a case control study
Hengwei Jin, Conghui Li, Huijian Ge, Yuhua Jiang, Youxiang Li
Leukemia cells induce changes in human bone marrow stromal cells
Sara Civini, Ping Jin, Jiaqiang Ren, Marianna Sabatino, Luciano Castiello, Jianjian Jin, Huan Wang, Yuanlong Zhao, Francesco Marincola, David Stroncek
Basic research and clinical applications of bisphosphonates in bone disease: what have we learned over the last 40 years?
Xiao-Long Xu, Wen-Long Gou, Ai-Yuan Wang, Yu Wang, Quan-Yi Guo, Qiang Lu, Shi-Bi Lu, Jiang Peng
MiR-92b inhibitor promoted glioma cell apoptosis via targeting DKK3 and blocking the Wnt/beta-catenin signaling pathway
Qifeng Li, Ke Shen, Yang Zhao, Chenkai Ma, Jianwen Liu, Jie Ma
Dietary hyperoxaluria is not reduced by treatment with lactic acid bacteria
Roswitha Siener, Diana J Bade, Albrecht Hesse, Bernd Hoppe
Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients
Branka Petricevic, Johannes Laengle, Josef Singer, Monika Sachet, Judit Fazekas, Guenther Steger, Rupert Bartsch, Erika Jensen-Jarolim, Michael Bergmann
Analysis of organ-enriched microRNAs in plasma as an approach to development of Universal Screening Test: feasibility study
Kira S Sheinerman, Vladimir G Tsivinsky, Samuil R Umansky
Resveratrol promotes myogenesis and hypertrophy in murine myoblasts
Anna Montesano, Livio Luzi, Pamela Senesi, Nausicaa Mazzocchi, Ileana Terruzzi
VIRsiRNApred: a web server for predicting inhibition efficacy of siRNAs targeting human viruses
Abid Qureshi, Nishant Thakur, Manoj Kumar
Lanthanum carbonate prevents accelerated medial calcification in uremic rats: role of osteoclast-like activity
Yu Che, Chen Bing, Javed Akhtar, Zhao Tingting, Yu Kezhou, Wang Rong
TPX2 is a novel prognostic marker for the growth and metastasis of colon cancer
Ping Wei, Nu Zhang, Ye Xu, Xinxiang Li, Debing Shi, Yuwei Wang, Dawei Li, Sanjun Cai
Pancreatic-carcinoma-cell-derived pro-angiogenic factors can induce endothelial-cell differentiation of a subset of circulating CD34+ progenitors
Barbara Vizio, Fiorella Biasi, Tiziana Scirelli, Anna Novarino, Adriana Prati, Libero Ciuffreda, Giuseppe Montrucchio, Giuseppe Poli, Graziella Bellone
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Feng Xin, Yongyi Yuan, Xiaoming Deng, Mingyu Han, Guojian Wang, Jiandong Zhao, Xue Gao, Jun Liu, Fei Yu, Dongyi Han, Pu Dai
Comparative analysis of curative effect of CT-guided stem cell transplantation and open surgical transplantation for sequelae of spinal cord injury
Guanghui Dai, Xuebin Liu, Zan Zhang, Xiaodong Wang, Min Li, Hongbin Cheng, Rongrong Hua, Jing Shi, Renzhi Wang, Chuan Qin, Jianhua Gao, Yihua An
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Xiaofang Xing, Shenyi Lian, Ying Hu, Ziyu Li, Lianhai Zhang, Xianzi Wen, Hong Du, Yongning Jia, Zhixue Zheng, Lin Meng, Chengchao Shou, Jiafu Ji
E2A suppresses invasion and migration by targeting YAP in colorectal cancer cells
Hongchao Zhao, Ao Huang, Pu Li, Yingjun Quan, Bo Feng, Xuehua Chen, Zhihai Mao, Zhenggang Zhu, Minhua Zheng
TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors
Marianna Marconato Rettori, Ana Carolina de Carvalho, Ana Luiza Bomfim Longo, Cleyton Zanardo de Oliveira, Luiz Paulo Kowalski, André Lopes Carvalho, André Luiz Vettore
Molecular signatures mostly associated with NK cells are predictive of relapse free survival in breast cancer patients
Maria Libera Ascierto, Michael O Idowu, Yingdong Zhao, Hanif Khalak, Kyle K Payne, Xiang-Yang Wang, Catherine I Dumur, Davide Bedognetti, Sara Tomei, Paolo A Ascierto, Anil Shanker, Harry D Bear, Ena Wang, Francesco M Marincola, Andrea De Maria, Masoud H Manjili
Clear cell renal cell carcinoma associated microRNA expression signatures identified by an integrated bioinformatics analysis
Jiajia Chen, Daqing Zhang, Wenyu Zhang, Yifei Tang, Wenying Yan, Lingchuan Guo, Bairong Shen
Modulation of cardiometabolic pathways in skin and serum from patients with psoriasis
Nehal N Mehta, Katherine Li, Philippe Szapary, James Krueger, Carrie Brodmerkel
Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice
Zhen-Zhou Zhang, Qian-Hui Shang, Hai-Yan Jin, Bei Song, Gavin Y Oudit, Lin Lu, Tong Zhou, Ying-Le Xu, Ping-Jin Gao, Ding-Liang Zhu, Josef M Penninger, Jiu-Chang Zhong
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Ming-Yi Xu, Xiao-Fang Jia, Ying Qu, Rui-Dan Zheng, Zheng-Hong Yuan, Hong-Lei Weng, Steven Dooley, Xing-Peng Wang, Li-Jun Zhang, Lun-Gen Lu
Saturable human neopterin response to interferon-α assessed by a pharmacokinetic-pharmacodynamic model
Sangil Jeon, Jae-Hyeon Juhn, Seunghoon Han, Jongtae Lee, Taegon Hong, Jeongki Paek, Dong-Seok Yim
Spatial organization of dendritic cells within tumor draining lymph nodes impacts clinical outcome in breast cancer patients
Andrew Y Chang, Nupur Bhattacharya, Jian Mu, A Francesca Setiadi, Valeria Carcamo-Cavazos, Gerald H Lee, Diana L Simons, Sina Yadegarynia, Kaveh Hemati, Adam Kapelner, Zheng Ming, David N Krag, Erich J Schwartz, Danny Z Chen, Peter P Lee
Effective visualization of integrated knowledge and data to enable informed decisions in drug development and translational medicine
Lena Brynne, Anders Bresell, Niclas Sjögren
Comprehensive analysis of the percentage of surface receptors and cytotoxic granules positive natural killer cells in patients with pancreatic cancer, gastric cancer, and colorectal cancer
Yun-Peng Peng, Yi Zhu, Jing-Jing Zhang, Ze-Kuan Xu, Zhu-Yin Qian, Cun-Cai Dai, Kui-Rong Jiang, Jun-Li Wu, Wen-Tao Gao, Qiang Li, Qing Du, Yi Miao
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Mariam El Assar, Juan Carlos Ruiz de Adana, Javier Angulo, María Luz Pindado Martínez, Alberto Hernández Matías, Leocadio Rodríguez-Mañas
MiR-370 sensitizes chronic myeloid leukemia K562 cells to homoharringtonine by targeting Forkhead box M1
MinRan Zhou, JiPing Zeng, XiaoMing Wang, Qing Guo, Tao Huang, HaiYu Shen, Yue Fu, LiXiang Wang, JiHui Jia, ChunYan Chen
Identification of serum insulin-like growth factor binding protein 1 as diagnostic biomarker for early-stage alcohol-induced liver disease
Heng-Hong Li, Kathryn Doiron, Andrew D Patterson, Frank J Gonzalez, Albert J Fornace Jr
Exendin-4 and sitagliptin protect kidney from ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction
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Limin Long, Guoqing Huang, Hongyi Zhu, Yonghong Guo, Youshuo Liu, Jirong Huo
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Yin Zhao, Hua Li, Li-li Men, Rong-chong Huang, Hai-cheng Zhou, Qian Xing, Jun-jie Yao, Chun-hong Shi, Jian-ling Du
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Jingkun Zhao, Pu Li, Hao Feng, Puxiongzhi Wang, Yaping Zong, Junjun Ma, Zhuo Zhang, Xuehua Chen, Minhua Zheng, Zhenggang Zhu, Aiguo Lu
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