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31.07.2018 | Systematic Reviews and Meta-analyses | Ausgabe 5/2018

Langenbeck's Archives of Surgery 5/2018

Karydakis flap reconstruction versus Limberg flap transposition for pilonidal sinus disease: a meta-analysis of randomized controlled trials

Zeitschrift:
Langenbeck's Archives of Surgery > Ausgabe 5/2018
Autoren:
Dimitrios Prassas, Thomas-Marten Rolfs, Franz-Josef Schumacher, Andreas Krieg
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s00423-018-1697-7) contains supplementary material, which is available to authorized users.

Abstract

Introduction

The definitive treatment of pilonidal sinus disease (PSD) is surgical. There is still no consensus as to the most appropriate off-midline primary closure technique. The aim of this meta-analysis has been to compare Karydakis flap reconstruction (KF) to Limberg flap transposition (LF) with regard to short- and long-term postoperative outcomes.

Methods

A systematic literature search for randomized controlled trials (RCTs) comparing KF to LF was performed. Data regarding postoperative outcomes were extracted and compared by meta-analysis. The odds ratio and standardized mean differences with 95% confidence intervals (CIs) were calculated.

Results

Eight RCTs were identified comparing KF (n = 554) to LF (n = 567). There was no significant difference noted between KF and LF with regard to the primary outcome variable, recurrence rate (OR = 1.07; 95% CI [0.59–1.92]; p = 0.83; 7 studies; I2 = 40%). LF was associated with a lower rate of post-operative seroma (OR = 2.03; 95% CI [1.15, 3.59]; p = 0.01; 7 studies; I2 = 0%). No further significant differences were noted in the secondary endpoints between the two study groups.

Conclusions

Recurrence rates of PSD were found to be similar in both study groups. Post-operative seroma rate was significantly higher in the KF group. The meta-analysis did not indicate any further statistically significant differences between the two surgical procedures.

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Zusatzmaterial
ESM 1 (DOCX 28 kb)
423_2018_1697_MOESM1_ESM.docx
Literatur
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