Skip to main content
Erschienen in: Die Orthopädie 7/2021

25.06.2021 | Genu valgum | Leitthema

Kniegelenksnahe Wachstumsmodulation durch Hemiepiphysiodese

Neue Operationstechniken: Fortschritte und Risiken

verfasst von: Dr. B. Vogt, A. Frommer, G. Gosheger, G. Toporowski, H. Tretow, R. Rödl, A. Laufer

Erschienen in: Die Orthopädie | Ausgabe 7/2021

Einloggen, um Zugang zu erhalten

Zusammenfassung

Die Korrektur von Achsfehlstellungen der unteren Extremität in der Frontalebene zählt zu den wesentlichen Aufgaben der Kinderorthopädie. Im Kindes- und Jugendalter kann das Wachstumspotenzial der Epiphysenfugen zum operativen Ausgleich dieser Beinachsendeformitäten genutzt werden. Die Wachstumsmodulation mittels Hemiepiphysiodese (HED) wird durch eine permanente oder temporäre asymmetrische Blockierung der Epiphysenfuge erreicht. Bei der permanenten HED erfolgt eine irreversible Destruktion der Wachstumsfuge, weshalb eine exakte Bestimmung des Interventionszeitpunktes unabdingbar ist. Die temporäre HED mittels Tension-Band-Implantaten wie 2‑Loch-Platten und flexiblen Klammern hat sich mittlerweile mit ausgezeichneten Ergebnissen als Standardmethode zur Wachstumslenkung etabliert. Implantatassoziierte Komplikationen konnten durch stetige Modifikation der Implantate bedeutend reduziert werden. Verschiedene experimentelle Verfahren besitzen das Potenzial zur Durchführung einer Wachstumsmodulation, möglicherweise sogar ohne die Notwendigkeit einer chirurgischen Intervention.
Literatur
1.
Zurück zum Zitat Azzolino AM, Herzenberg JE (2015) Air physiogram: technique for visualization of the resected physis in percutaneous epiphysiodesis. Orthopedics 38:170–174PubMed Azzolino AM, Herzenberg JE (2015) Air physiogram: technique for visualization of the resected physis in percutaneous epiphysiodesis. Orthopedics 38:170–174PubMed
3.
Zurück zum Zitat Bisland SK, Johnson C, Diab M et al (2007) A new technique for physiodesis using photodynamic therapy. Clin Orthop Relat Res 461:153–161PubMed Bisland SK, Johnson C, Diab M et al (2007) A new technique for physiodesis using photodynamic therapy. Clin Orthop Relat Res 461:153–161PubMed
4.
Zurück zum Zitat Blount WP, Clarke GR (1949) Control of bone growth by epiphyseal stapling; a preliminary report. J Bone Joint Surg Am 31A:464–478PubMed Blount WP, Clarke GR (1949) Control of bone growth by epiphyseal stapling; a preliminary report. J Bone Joint Surg Am 31A:464–478PubMed
5.
Zurück zum Zitat Bohm S, Krieg AH, Hefti F et al (2013) Growth guidance of angular lower limb deformities using a one-third two-hole tubular plate. J Child Orthop 7:289–294PubMedPubMedCentral Bohm S, Krieg AH, Hefti F et al (2013) Growth guidance of angular lower limb deformities using a one-third two-hole tubular plate. J Child Orthop 7:289–294PubMedPubMedCentral
6.
Zurück zum Zitat Bowen JR, Johnson WJ (1984) Percutaneous epiphysiodesis. Clin Orthop Relat Res (190):170–173 Bowen JR, Johnson WJ (1984) Percutaneous epiphysiodesis. Clin Orthop Relat Res (190):170–173
7.
Zurück zum Zitat Burghardt RD, Herzenberg JE, Standard SC et al (2008) Temporary hemiepiphyseal arrest using a screw and plate device to treat knee and ankle deformities in children: a preliminary report. J Child Orthop 2:187–197PubMedPubMedCentral Burghardt RD, Herzenberg JE, Standard SC et al (2008) Temporary hemiepiphyseal arrest using a screw and plate device to treat knee and ankle deformities in children: a preliminary report. J Child Orthop 2:187–197PubMedPubMedCentral
8.
Zurück zum Zitat Burghardt RD, Kanellopoulos AD, Herzenberg JE (2011) Hemiepiphyseal arrest in a porcine model. J Pediatr Orthop 31:e25–e29PubMed Burghardt RD, Kanellopoulos AD, Herzenberg JE (2011) Hemiepiphyseal arrest in a porcine model. J Pediatr Orthop 31:e25–e29PubMed
9.
Zurück zum Zitat Burghardt RD, Specht SC, Herzenberg JE (2010) Mechanical failures of eight-plateguided growth system for temporary hemiepiphysiodesis. J Pediatr Orthop 30:594–597PubMed Burghardt RD, Specht SC, Herzenberg JE (2010) Mechanical failures of eight-plateguided growth system for temporary hemiepiphysiodesis. J Pediatr Orthop 30:594–597PubMed
11.
Zurück zum Zitat Canale ST, Christian CA (1990) Techniques for epiphysiodesis about the knee. Clin Orthop Relat Res (255):81–85 Canale ST, Christian CA (1990) Techniques for epiphysiodesis about the knee. Clin Orthop Relat Res (255):81–85
12.
Zurück zum Zitat Degreef I, Moens P, Fabry G (2003) Temporary epiphysiodesis with Blount stapling for treatment of idiopathic genua valga in children. Acta Orthop Belg 69:426–432PubMed Degreef I, Moens P, Fabry G (2003) Temporary epiphysiodesis with Blount stapling for treatment of idiopathic genua valga in children. Acta Orthop Belg 69:426–432PubMed
13.
Zurück zum Zitat Eltayeby HH, Iobst CA, Herzenberg JE (2019) Hemiepiphysiodesis using tension band plates: does the initial screw angle influence the rate of correction? J Child Orthop 13:62–66PubMedPubMedCentral Eltayeby HH, Iobst CA, Herzenberg JE (2019) Hemiepiphysiodesis using tension band plates: does the initial screw angle influence the rate of correction? J Child Orthop 13:62–66PubMedPubMedCentral
14.
Zurück zum Zitat Farr S, Alrabai HM, Meizer E et al (2018) Rebound of frontal plane malalignment after tension band plating. J Pediatr Orthop 38:365–369PubMed Farr S, Alrabai HM, Meizer E et al (2018) Rebound of frontal plane malalignment after tension band plating. J Pediatr Orthop 38:365–369PubMed
15.
Zurück zum Zitat Ferrick MR, Birch JG, Albright M (2004) Correction of non-Blount’s angular knee deformity by permanent hemiepiphyseodesis. J Pediatr Orthop 24:397–402PubMed Ferrick MR, Birch JG, Albright M (2004) Correction of non-Blount’s angular knee deformity by permanent hemiepiphyseodesis. J Pediatr Orthop 24:397–402PubMed
16.
Zurück zum Zitat Ghanem I, El Hage S, Diab M et al (2009) Radiofrequency application to the growth plate in the rabbit: a new potential approach to epiphysiodesis. J Pediatr Orthop 29:629–635PubMed Ghanem I, El Hage S, Diab M et al (2009) Radiofrequency application to the growth plate in the rabbit: a new potential approach to epiphysiodesis. J Pediatr Orthop 29:629–635PubMed
17.
Zurück zum Zitat Ghanem I, Karam JA, Widmann RF (2011) Surgical epiphysiodesis indications and techniques: update. Curr Opin Pediatr 23:53–59PubMed Ghanem I, Karam JA, Widmann RF (2011) Surgical epiphysiodesis indications and techniques: update. Curr Opin Pediatr 23:53–59PubMed
18.
Zurück zum Zitat Gottliebsen M, Shiguetomi-Medina JM, Rahbek O et al (2016) Guided growth: mechanism and reversibility of modulation. J Child Orthop 10:471–477PubMedPubMedCentral Gottliebsen M, Shiguetomi-Medina JM, Rahbek O et al (2016) Guided growth: mechanism and reversibility of modulation. J Child Orthop 10:471–477PubMedPubMedCentral
19.
Zurück zum Zitat Haas S (1945) Retardation of bone growth by a wire loop. J Bone Joint Surg Am 27:25–36 Haas S (1945) Retardation of bone growth by a wire loop. J Bone Joint Surg Am 27:25–36
20.
Zurück zum Zitat Horton GA, Olney BW (1996) Epiphysiodesis of the lower extremity: results of the percutaneous technique. J Pediatr Orthop 16:180–182PubMed Horton GA, Olney BW (1996) Epiphysiodesis of the lower extremity: results of the percutaneous technique. J Pediatr Orthop 16:180–182PubMed
21.
Zurück zum Zitat Inan M, Chan G, Littleton AG et al (2008) Efficacy and safety of percutaneous epiphysiodesis. J Pediatr Orthop 28:648–651PubMed Inan M, Chan G, Littleton AG et al (2008) Efficacy and safety of percutaneous epiphysiodesis. J Pediatr Orthop 28:648–651PubMed
22.
Zurück zum Zitat Jelinek EM, Bittersohl B, Martiny F et al (2012) The 8‑plate versus physeal stapling for temporary hemiepiphyseodesis correcting genu valgum and genu varum: a retrospective analysis of thirty five patients. Int Orthop 36:599–605PubMed Jelinek EM, Bittersohl B, Martiny F et al (2012) The 8‑plate versus physeal stapling for temporary hemiepiphyseodesis correcting genu valgum and genu varum: a retrospective analysis of thirty five patients. Int Orthop 36:599–605PubMed
23.
Zurück zum Zitat Kadhim M, Gauthier L, Logan K et al (2018) Guided growth for angular correction in children: a comparison of two tension band plate designs. J Pediatr Orthop B 27:1–7PubMed Kadhim M, Gauthier L, Logan K et al (2018) Guided growth for angular correction in children: a comparison of two tension band plate designs. J Pediatr Orthop B 27:1–7PubMed
24.
Zurück zum Zitat Keshet D, Katzman A, Eidelman M (2018) Removing only the metaphyseal screw after completion of deformity correction with 8‑plate hemiepiphysiodesis. Is it wise and safe? J Child Orthop 12(Suppl 1):54 Keshet D, Katzman A, Eidelman M (2018) Removing only the metaphyseal screw after completion of deformity correction with 8‑plate hemiepiphysiodesis. Is it wise and safe? J Child Orthop 12(Suppl 1):54
25.
Zurück zum Zitat Khoury JG, Tavares JO, Mcconnell S et al (2007) Results of screw epiphysiodesis for the treatment of limb length discrepancy and angular deformity. J Pediatr Orthop 27:623–628PubMed Khoury JG, Tavares JO, Mcconnell S et al (2007) Results of screw epiphysiodesis for the treatment of limb length discrepancy and angular deformity. J Pediatr Orthop 27:623–628PubMed
26.
Zurück zum Zitat Koob S, Kehrer M, Hettchen M et al (2018) Temporary epiphysiodesis using the FlexTack implant (tension band) featuring a modified explantation technique. Operat Orthop Traumatol 30:359–368 Koob S, Kehrer M, Hettchen M et al (2018) Temporary epiphysiodesis using the FlexTack implant (tension band) featuring a modified explantation technique. Operat Orthop Traumatol 30:359–368
27.
Zurück zum Zitat Lee HJ, Oh CW, Song KS et al (2012) Guided growth with a noncannulated screw-plate system for angular deformity of the knee: a preliminary report. J Pediatr Orthop B 21:339–347PubMed Lee HJ, Oh CW, Song KS et al (2012) Guided growth with a noncannulated screw-plate system for angular deformity of the knee: a preliminary report. J Pediatr Orthop B 21:339–347PubMed
28.
Zurück zum Zitat Lee MC, Bier AD, Nickisch F et al (2007) Epiphysiodesis with infusion of stromal cell-derived factor‑1 in rabbit growth plates. J Bone Joint Surg Am 89:102–113PubMed Lee MC, Bier AD, Nickisch F et al (2007) Epiphysiodesis with infusion of stromal cell-derived factor‑1 in rabbit growth plates. J Bone Joint Surg Am 89:102–113PubMed
29.
Zurück zum Zitat Metaizeau JP, Wong-Chung J, Bertrand H et al (1998) Percutaneous epiphysiodesis using transphyseal screws (PETS). J Pediatr Orthop 18:363–369PubMed Metaizeau JP, Wong-Chung J, Bertrand H et al (1998) Percutaneous epiphysiodesis using transphyseal screws (PETS). J Pediatr Orthop 18:363–369PubMed
30.
Zurück zum Zitat Mielke CH, Stevens PM (1996) Hemiepiphyseal stapling for knee deformities in children younger than 10 years: a preliminary report. J Pediatr Orthop 16:423–429PubMed Mielke CH, Stevens PM (1996) Hemiepiphyseal stapling for knee deformities in children younger than 10 years: a preliminary report. J Pediatr Orthop 16:423–429PubMed
31.
Zurück zum Zitat Morein G, Gassner S, Kaplan I (1978) Bone growth alterations resulting from application of CO2 laser beam to the epiphyseal growth plates. An experimental study in rabbits. Acta Orthop Scand 49:244–248PubMed Morein G, Gassner S, Kaplan I (1978) Bone growth alterations resulting from application of CO2 laser beam to the epiphyseal growth plates. An experimental study in rabbits. Acta Orthop Scand 49:244–248PubMed
32.
Zurück zum Zitat Phemister D (1933) Operative arrestment of longitudinal growth of bone in the treatment of deformities. J Bone Joint Surg Am 15:1–15 Phemister D (1933) Operative arrestment of longitudinal growth of bone in the treatment of deformities. J Bone Joint Surg Am 15:1–15
33.
Zurück zum Zitat Raab P, Wild A, Seller K et al (2001) Correction of length discrepancies and angular deformities of the leg by Blount’s epiphyseal stapling. Eur J Pediatr 160:668–674PubMed Raab P, Wild A, Seller K et al (2001) Correction of length discrepancies and angular deformities of the leg by Blount’s epiphyseal stapling. Eur J Pediatr 160:668–674PubMed
34.
Zurück zum Zitat Ramseier LE, Sukthankar A, Exner GU (2009) Minimal invasive epiphysiodesis using a modified „Canale“-technique for correction of angular deformities and limb leg length discrepancies. J Child Orthop 3:33–37PubMedPubMedCentral Ramseier LE, Sukthankar A, Exner GU (2009) Minimal invasive epiphysiodesis using a modified „Canale“-technique for correction of angular deformities and limb leg length discrepancies. J Child Orthop 3:33–37PubMedPubMedCentral
35.
Zurück zum Zitat Rosen MA, Beer KJ, Wiater JP et al (1990) Epiphysiodesis by electrocautery in the rabbit and dog. Clin Orthop Relat Res (256):244–253 Rosen MA, Beer KJ, Wiater JP et al (1990) Epiphysiodesis by electrocautery in the rabbit and dog. Clin Orthop Relat Res (256):244–253
36.
Zurück zum Zitat Sansone JM, Wilsman NJ, Leiferman EM et al (2009) The effect of periosteal resection on tibial growth velocity measured by microtransducer technology in lambs. J Pediatr Orthop 29:61–67PubMedPubMedCentral Sansone JM, Wilsman NJ, Leiferman EM et al (2009) The effect of periosteal resection on tibial growth velocity measured by microtransducer technology in lambs. J Pediatr Orthop 29:61–67PubMedPubMedCentral
38.
Zurück zum Zitat Schroerlucke S, Bertrand S, Clapp J et al (2009) Failure of Orthofix eight-plate for the treatment of Blount disease. J Pediatr Orthop 29:57–60PubMed Schroerlucke S, Bertrand S, Clapp J et al (2009) Failure of Orthofix eight-plate for the treatment of Blount disease. J Pediatr Orthop 29:57–60PubMed
40.
Zurück zum Zitat Stevens PM (2007) Guided growth for angular correction: a preliminary series using a tension band plate. J Pediatr Orthop 27:253–259PubMed Stevens PM (2007) Guided growth for angular correction: a preliminary series using a tension band plate. J Pediatr Orthop 27:253–259PubMed
41.
Zurück zum Zitat Stevens PM (2016) Growth modulation for angular and length correction. In: Sabharwal S (Hrsg) Pediatric lower limb deformities: principles and techniques of management. Springer, Cham, S 51–66 Stevens PM (2016) Growth modulation for angular and length correction. In: Sabharwal S (Hrsg) Pediatric lower limb deformities: principles and techniques of management. Springer, Cham, S 51–66
42.
Zurück zum Zitat Stevens PM, Maguire M, Dales MD et al (1999) Physeal stapling for idiopathic genu valgum. J Pediatr Orthop 19:645–649PubMed Stevens PM, Maguire M, Dales MD et al (1999) Physeal stapling for idiopathic genu valgum. J Pediatr Orthop 19:645–649PubMed
43.
Zurück zum Zitat Struwe C, Walter SG, Druschel C et al (2021) Biomechanical evaluation of temporary epiphysiodesis at the femoral epiphysis using established devices from clinical practice. J Mater Sci Mater Med 32:41PubMedPubMedCentral Struwe C, Walter SG, Druschel C et al (2021) Biomechanical evaluation of temporary epiphysiodesis at the femoral epiphysis using established devices from clinical practice. J Mater Sci Mater Med 32:41PubMedPubMedCentral
44.
Zurück zum Zitat Vogt B, Kleine-König M‑T, Gosheger G et al (2016) FlexTackTM and RigidTackTM: new devices for correction of angular deformities and leg length discrepancies by temporary epiphysiodesis. J Child Orthop 10:17–18 Vogt B, Kleine-König M‑T, Gosheger G et al (2016) FlexTackTM and RigidTackTM: new devices for correction of angular deformities and leg length discrepancies by temporary epiphysiodesis. J Child Orthop 10:17–18
45.
Zurück zum Zitat Vogt B, Schiedel F, Rodl R (2014) Guided growth in children and adolescents. Correction of leg length discrepancies and leg axis deformities. Orthopade 43:267–284PubMed Vogt B, Schiedel F, Rodl R (2014) Guided growth in children and adolescents. Correction of leg length discrepancies and leg axis deformities. Orthopade 43:267–284PubMed
47.
Zurück zum Zitat Waris E, Ashammakhi N, Kelly CP et al (2005) Transphyseal bioabsorbable screws cause temporary growth retardation in rabbit femur. J Pediatr Orthop 25:342–345PubMed Waris E, Ashammakhi N, Kelly CP et al (2005) Transphyseal bioabsorbable screws cause temporary growth retardation in rabbit femur. J Pediatr Orthop 25:342–345PubMed
48.
Zurück zum Zitat Widmann RF, Amaral TD, Yildiz C et al (2010) Percutaneous radiofrequency epiphysiodesis in a rabbit model: a pilot study. Clin Orthop Relat Res 468:1943–1948PubMedPubMedCentral Widmann RF, Amaral TD, Yildiz C et al (2010) Percutaneous radiofrequency epiphysiodesis in a rabbit model: a pilot study. Clin Orthop Relat Res 468:1943–1948PubMedPubMedCentral
49.
Zurück zum Zitat Wiemann JMT, Tryon C, Szalay EA (2009) Physeal stapling versus 8‑plate hemiepiphysiodesis for guided correction of angular deformity about the knee. J Pediatr Orthop 29:481–485PubMed Wiemann JMT, Tryon C, Szalay EA (2009) Physeal stapling versus 8‑plate hemiepiphysiodesis for guided correction of angular deformity about the knee. J Pediatr Orthop 29:481–485PubMed
Metadaten
Titel
Kniegelenksnahe Wachstumsmodulation durch Hemiepiphysiodese
Neue Operationstechniken: Fortschritte und Risiken
verfasst von
Dr. B. Vogt
A. Frommer
G. Gosheger
G. Toporowski
H. Tretow
R. Rödl
A. Laufer
Publikationsdatum
25.06.2021
Verlag
Springer Medizin
Schlagwörter
Genu valgum
Genu varum
Erschienen in
Die Orthopädie / Ausgabe 7/2021
Print ISSN: 2731-7145
Elektronische ISSN: 2731-7153
DOI
https://doi.org/10.1007/s00132-021-04122-8

Weitere Artikel der Ausgabe 7/2021

Die Orthopädie 7/2021 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.