nach oben

Breast Cancer Research

Erschienen in:

01.06.2005 | Poster Presentation

Lack of evidence for nuclear IGFBP5 in mammary epithelial cells

verfasst von: C Berlato, A Jurgeit, S Geley, W Doppler

Erschienen in: Breast Cancer Research | Sonderheft 2/2005

Einloggen, um Zugang zu erhalten

Excerpt

IGFBP5 plays a role in mediating the effects of IGFs, which are important in mammary gland development [1] and carcinogenesis [2]. IGF-independent effects of IGFBP5 have also been described and it has been postulated that these are at least partially mediated via IGFBP5 localized in the nucleus [3, 4]. …

Allan GJ, Beattie J, Flint DJ: The role of IGFBP-5 in mammary gland development and involution. Domest Anim Endocrinol. 2004, 27: 257-266. 10.1016/j.domaniend.2004.06.009.CrossRefPubMed

Pollak MN, Schernhammer ES, Hankinson SE: Insulin-like growth factors and neoplasia. Nat Rev Cancer. 2004, 4: 505-518. 10.1038/nrc1387.CrossRefPubMed

Schedlich LJ, Le Page SL, Firth SM, Briggs LJ, Jans DA, Baxter RC: Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit. J Biol Chem. 2000, 275: 23462-23470. 10.1074/jbc.M002208200.CrossRefPubMed

Xu Q, Li S, Zhao Y, Maures TJ, Yin P, Duan C: Evidence that IGF binding protein-5 functions as a ligand-independent transcriptional regulator in vascular smooth muscle cells. Circ Res. 2004, 94: e46-e54. 10.1161/01.RES.0000124761.62846.DF.CrossRefPubMed

Titel: Lack of evidence for nuclear IGFBP5 in mammary epithelial cells
verfasst von: C Berlato
A Jurgeit
S Geley
W Doppler
Publikationsdatum: 01.06.2005
Verlag: BioMed Central
Erschienen in: Breast Cancer Research / Ausgabe Sonderheft 2/2005
Elektronische ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr1142

Neu im Fachgebiet Onkologie

19.04.2024 | EAU 2024 | Kongressbericht | Nachrichten

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Lack of evidence for nuclear IGFBP5 in mammary epithelial cells

Excerpt

Neu im Fachgebiet Onkologie

Prostatakarzinom: EU initiiert neues Screeningkonzept

Blasenkarzinom – Biomarker statt Zytologie?

Stereotaktische Radiatio schlägt konventionelle Bestrahlung

Adjuvante Brustkrebstherapie: Doppelt hält besser

Update Onkologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Sonderheft 2/2005

High-throughput experimental verification of predicted tissue-specific and tumor-specific splice isoforms

Application of microarray analyses to identify genes involved in radiation-induced fibrosis

The interaction of the ER with ERBB2 and PI3K results in elevated levels of AKT and p90RSK in tamoxifen-resistant MCF-7 cells

Molecular prediction of tamoxifen resistance in breast cancer

Determining the factors affecting breast cancer infectivity by oncolytic adenovirus

Comparison of the expression profile in breast cancer and ovarian cancer

Neu im Fachgebiet Onkologie

Prostatakarzinom: EU initiiert neues Screeningkonzept

Blasenkarzinom – Biomarker statt Zytologie?

Stereotaktische Radiatio schlägt konventionelle Bestrahlung

Adjuvante Brustkrebstherapie: Doppelt hält besser

Update Onkologie