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Head and Neck Pathology
Erschienen in: Head and Neck Pathology 1/2013

01.03.2013 | Case Report

Lacrimal Gland Adenoid Cystic Carcinoma with High-Grade Transformation to Myoepithelial Carcinoma: Report of a Case and Review of Literature

verfasst von: Prokopios P. Argyris, Stefan E. Pambuccian, Zuzan Cayci, Charanjeet Singh, Konstantinos I. Tosios, Ioannis G. Koutlas

Erschienen in: Head and Neck Pathology | Ausgabe 1/2013

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Abstract

Adenoid cystic carcinoma (AdCC) is the most frequent malignant neoplasm of the lacrimal glands. Like its salivary gland counterpart, lacrimal AdCC can rarely undergo high-grade transformation (“dedifferentiation”). We herein report the clinical, radiographic and microscopic findings of a lacrimal gland AdCC with high grade transformation, occurring in a 39-year-old female patient. In contrast to salivary gland AdCC with high-grade transformation, which usually shows a high grade component with “ductal” differentiation, in the case presented, the “dedifferentiated” component showed morphologic and immunohistochemical features of myoepithelial differentiation.
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Metadaten
Titel
Lacrimal Gland Adenoid Cystic Carcinoma with High-Grade Transformation to Myoepithelial Carcinoma: Report of a Case and Review of Literature
verfasst von
Prokopios P. Argyris
Stefan E. Pambuccian
Zuzan Cayci
Charanjeet Singh
Konstantinos I. Tosios
Ioannis G. Koutlas
Publikationsdatum
01.03.2013
Verlag
Springer US
Erschienen in
Head and Neck Pathology / Ausgabe 1/2013
Elektronische ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-012-0383-2

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