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Erschienen in: HNO 1/2012

01.01.2012 | Leitthema

Larynxkarzinom

Epidemiologie, Risikofaktoren und Überleben

verfasst von: M. Pantel, Univ.-Prof. Dr. O. Guntinas-Lichius

Erschienen in: HNO | Ausgabe 1/2012

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Zusammenfassung

Das Larynxkarzinom gehört zu den häufigen Kopf-Hals-Tumoren mit einer rückläufigen Erkrankungsrate bei Männern und weiteren Zunahme bei Frauen. Die Inzidenz beträgt in Deutschland etwa 5–7/100.000 Personen/Jahr bei Männern und etwa 0,6–0,8/100.000 Personen/Jahr bei Frauen. Bedingt durch die höhere Lebenserwartung nimmt das mittlere Erkrankungsalter zu; bei adäquater Vorbereitung kann jedoch auch bei älteren Patienten eine Standardtherapie mit gleichen Überlebenschancen wie bei jüngeren durchgeführt werden. Tabakrauchen und Alkoholkonsum bleiben auch heute die dominierenden Risikofaktoren bei mehr als 80% der Patienten. Trotz einer Vielzahl von diagnostischen Neuerungen wird immer noch die Hälfte der Tumoren erst im fortgeschrittenen Stadium erkannt. Auch die Überlebensraten haben sich in Deutschland in den letzten 10 Jahren nicht signifikant verbessert. Die durchschnittliche 5-Jahres-Überlebensrate liegt in Deutschland bei etwa 60%. Über eine Abnahme der Überlebensraten, wie in den USA beobachtet, ist anderseits aber nicht zu berichten.
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Metadaten
Titel
Larynxkarzinom
Epidemiologie, Risikofaktoren und Überleben
verfasst von
M. Pantel
Univ.-Prof. Dr. O. Guntinas-Lichius
Publikationsdatum
01.01.2012
Verlag
Springer-Verlag
Erschienen in
HNO / Ausgabe 1/2012
Print ISSN: 0017-6192
Elektronische ISSN: 1433-0458
DOI
https://doi.org/10.1007/s00106-011-2423-8

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