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01.09.2012 | Case Report

Late-onset systemic lupus erythematosus-associated liver disease

verfasst von: Leonardo L. Schiavon, Roberto J. Carvalho-Filho, Janaína Luz Narciso-Schiavon, Valéria P. Lanzoni, Maria Lucia G. Ferraz, Antonio Eduardo B. Silva

Erschienen in: Rheumatology International | Ausgabe 9/2012

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Abstract

Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease, which predominantly affects women under 50 years old. Although liver disease is not included in the diagnostic criteria, abnormal liver tests are common among patients with SLE and, in a significant proportion of those patients, no other underlying condition can be identified. We described a case of liver involvement in late-onset SLE presenting with a predominantly cholestatic pattern. Other conditions associated with abnormal liver tests were excluded, and the patient showed a prompt response to steroid therapy. The spectrum of the liver involvement in SLE is discussed, with emphasis on the differential diagnosis with autoimmune hepatitis.

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Titel: Late-onset systemic lupus erythematosus-associated liver disease
verfasst von: Leonardo L. Schiavon
Roberto J. Carvalho-Filho
Janaína Luz Narciso-Schiavon
Valéria P. Lanzoni
Maria Lucia G. Ferraz
Antonio Eduardo B. Silva
Publikationsdatum: 01.09.2012
Verlag: Springer-Verlag
Erschienen in: Rheumatology International / Ausgabe 9/2012
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-010-1492-4

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