Erschienen in:
27.05.2016 | Case Report
Late relapsing mantle cell lymphoma showing preserved sensitivity to single-agent lenalidomide
verfasst von:
Adrian Tempescul, Jean-Christophe Ianotto, Cristina Bagacean, Pierre-Yves Salaun, Corina Bocsan, Mihnea Zdrenghea
Erschienen in:
International Journal of Hematology
|
Ausgabe 3/2016
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Abstract
Mantle cell lymphoma is a hematologic malignancy characterized by poor therapeutic outcomes. Immunomodulatory drugs are a focus of attention in this disease, especially for the elderly and frail patients not able to tolerate the typically intensive therapeutic approaches used in fitter patients. We here present the case of refractory mantle cell lymphoma of the elderly that achieved complete remission following the use of single-agent lenalidomide, and a second complete response to the same regimen on relapse 5 years later.