03.01.2022 | Sleep Breathing Physiology and Disorders • Review
Lateral pharyngoplasty vs. traditional uvulopalatopharyngoplasty for patients with OSA: systematic review and meta-analysis
Antonino Maniaci, Milena Di Luca, Jerome René Lechien, Giannicola Iannella, Calogero Grillo, Caterina Maria Grillo, Federico Merlino, Christian Calvo-Henriquez, Andrea De Vito, Giuseppe Magliulo, Annalisa Pace, Claudio Vicini, Salvatore Cocuzza, Vittoria Bannò, Isabella Pollicina, Giovanna Stilo, Alberto Bianchi, Ignazio La Mantia
Sleep and Breathing
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To compare the efficacy and success rates of lateral pharyngoplasty techniques (LP) vs. uvulopalatopharyngoplasty (UPPP) among adult patients surgically treated for obstructive sleep apnea.
A systematic literature review of the last 20 years’ papers was conducted using PubMed/Medline, Embase, Web of Science, Scholar, and the Cochrane Library until April 2021. Only full-text English articles comparing LP and UPPP outcomes in adult patients with objective outcomes were included in the study.
We included 9 articles for a total of 312 surgically treated patients with OSA. LP techniques for obstructive sleep apnea were used on 186 (60%) subjects, while 126 patients (40%) were treated with UPPP. Both surgical procedures resulted in significant improvements in apnea-hypopnea index (AHI), Epworth Sleepiness Scale (ESS) score, and lowest oxygen saturation (LOS) (p < 0.001 in all cases). Although better outcomes were reported with lateral pharyngoplasty, the differences were not significant compared to UPPP post-operative results (p > 0.05 in all cases).
UPPP and LP are both effective surgical procedures in treating OSA in adults. Although not significant, LPs demonstrated improved post-operative outcomes. However, further evidence comparing the surgical effect on patients with OSA is needed to discriminate post-operative outcomes.