11.03.2021 | Editorial
Left ventricular mechanical dyssynchrony in patients with heart failure: What is the next step?
verfasst von:
Feifei Zhang, MD, Yuetao Wang, MD
Erschienen in:
Journal of Nuclear Cardiology
|
Ausgabe 4/2022
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Excerpt
Left ventricular mechanical dyssynchrony (LVMD) is referred to incoordinate onset of mechanical contraction between the left ventricle (LV) segments,
1 leading to structural and functional alterations that may eventually result in heart failure (HF). LVMD is highly prevalent and has been extensively studied among patients with HF. It has been proven to be associated with an increased risk of major adverse cardiac events or presented incremental clinical value in prognosis and risk stratification among different subsets of HF patients with acute
2 or chronic,
3 ischemic
4,
5 or nonischemic,
6 reduced
7 or preserved left ventricular ejection fraction (LVrEF or LVpEF),
8 irrespective of narrow or wider QRS duration (QRSd).
9 However, its major clinical application is to select candidate for better prediction of optimal cardiac resynchronization therapy (CRT) outcomes in HF patients.
10-
12 …