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Erschienen in: Pediatric Cardiology 3/2020

21.02.2020 | Original Article

Left Ventricular Strain Normalizes After Balloon Aortic Valvuloplasty in Infants with Congenital Aortic Stenosis

verfasst von: Ashish A. Ankola, Michael P. DiLorenzo, Mariel E. Turner, Alejandro J. Torres, Matthew A. Crystal, Amee Shah

Erschienen in: Pediatric Cardiology | Ausgabe 3/2020

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Abstract

Severe aortic stenosis (AS) causes left ventricular (LV) afterload and subendocardial ischemia. Despite this, most infants with AS have normal LV ejection fraction (EF). Strain analysis using two-dimensional speckle tracking echocardiography (2DSTE) may identify more sensitive markers of systolic dysfunction. We sought to show changes in LV strain after balloon aortic valvuloplasty (BAV) in infants with AS. Twenty-seven infants ≤ 1 year of age with AS who underwent BAV from 2007 to 2017 were included. Echocardiograms before/after BAV were retrospectively analyzed with 2DSTE. Median age was 29 days (interquartile range 3–52) and LV EF was 64 ± 10%. Global longitudinal strain (GLS) significantly improved post-BAV (− 17 ± 5 vs. − 20 ± 4%, p = 0.001) with no difference in global circumferential strain. Peak longitudinal strain was abnormal at the inferoseptal base and mid-ventricle (− 15 ± 6 and − 17 ± 5 = 7%, respectively) and significantly improved in the basal and mid-anterolateral segments (− 17 ± 5 vs. − 21 ± 5%, p < 0.01; − 17 ± 6% vs. − 20 ± 5%, p = 0.01, respectively). Five (20%) patients underwent reintervention, and had significantly higher peak-to-peak pre and post-BAV AS gradients (86 ± 14 vs. 61 ± 20 mmHg, p = 0.02; 33 ± 17 vs. 21 ± 10 mmHg, p = 0.04, respectively). In conclusion, longitudinal strain is abnormal in infants with AS and improves to previously published normal values after BAV.
Literatur
5.
Zurück zum Zitat Patel S, Saini AP, Nair A, Weber HS (2015) Transcarotid balloon valvuloplasty in neonates and small infants with critical aortic valve stenosis utilizing continuous transesophageal echocardiographic guidance: a 22 year single center experience from the cath lab to the bedside. Catheter Cardiovasc Interv 86:821–827. https://doi.org/10.1002/ccd.26036 CrossRefPubMed Patel S, Saini AP, Nair A, Weber HS (2015) Transcarotid balloon valvuloplasty in neonates and small infants with critical aortic valve stenosis utilizing continuous transesophageal echocardiographic guidance: a 22 year single center experience from the cath lab to the bedside. Catheter Cardiovasc Interv 86:821–827. https://​doi.​org/​10.​1002/​ccd.​26036 CrossRefPubMed
10.
Zurück zum Zitat Dandel M, Lehmkuhl H, Knosalla C et al (2009) Strain and strain rate imaging by echocardiography—basic concepts and clinical applicability. Curr Cardiol Rev 5:133–148CrossRef Dandel M, Lehmkuhl H, Knosalla C et al (2009) Strain and strain rate imaging by echocardiography—basic concepts and clinical applicability. Curr Cardiol Rev 5:133–148CrossRef
14.
18.
Zurück zum Zitat Suzuki-eguchi N, Id MM, Itabashi Y et al (2018) Prognostic value of pre-procedural left ventricular strain for clinical events after transcatheter aortic valve implantation. PLoS ONE 13:1–11CrossRef Suzuki-eguchi N, Id MM, Itabashi Y et al (2018) Prognostic value of pre-procedural left ventricular strain for clinical events after transcatheter aortic valve implantation. PLoS ONE 13:1–11CrossRef
Metadaten
Titel
Left Ventricular Strain Normalizes After Balloon Aortic Valvuloplasty in Infants with Congenital Aortic Stenosis
verfasst von
Ashish A. Ankola
Michael P. DiLorenzo
Mariel E. Turner
Alejandro J. Torres
Matthew A. Crystal
Amee Shah
Publikationsdatum
21.02.2020
Verlag
Springer US
Erschienen in
Pediatric Cardiology / Ausgabe 3/2020
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-020-02322-1

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