The online version of this article (doi:10.1186/1477-7819-10-120) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests.
WQ and CXY wrote the main manuscript and performed the operation, JJ and JMS prepared the histological figures, WC and LGD provided the clinical history and clinical figures. All authors read and approved the final manuscript.
Leiomyosarcoma of the inferior vena cava (IVCL) is a rare retroperitoneal tumor. We report two cases of level II (middle level, renal veins to hepatic veins) IVCL, who underwent en bloc resection with reconstruction of bilateral or left renal venous return using prosthetic grafts. In our cases, IVCL is documented to be occluded preoperatively, therefore, radical resection of tumor and/or right kidney was performed and the distal end of inferior vena cava was resected and without caval reconstruction. None of the patients developed edema or acute renal failure postoperatively. After surgical resection, adjuvant radiation therapy was administrated. The patients have been free of recurrence 2 years and 3 months, 9 months after surgery, respectively, indicating the complete surgical resection and radiotherapy contribute to the better survival. The reconstruction of inferior vena cava was not considered mandatory in level II IVCL, if the retroperitoneal venous collateral pathways have been established. In addition to the curative resection of IVCL, the renal vascular reconstruction minimized the risks of procedure-related acute renal failure, and was more physiologically preferable. This concept was reflected in the treatment of the two patients reported on.
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- Leiomyosarcoma of the inferior vena cava level II involvement: curative resection and reconstruction of renal veins
- BioMed Central
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