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01.12.2014 | Myelodysplastic Syndromes (M Sekeres, Section Editor)

Lessons from the Atomic Bomb About Secondary MDS

verfasst von: Tomoko Hata, Daisuke Imanishi, Yasushi Miyazaki

Erschienen in: Current Hematologic Malignancy Reports | Ausgabe 4/2014

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Abstract

Myelodysplastic syndromes (MDSs) is a hematological neoplasm defined by ineffective hematopoiesis, dysplasia of hematopoietic cells, and risk of progression to acute leukemia. MDS occurs as de novo or secondary, and chemoradiotherapy for cancers is thought to increase the risk of MDS among patients. Recently, an epidemiological study for MDS among A-bomb survivors was performed, and it clearly demonstrated that the exposure to external radiation significantly increased the risk of MDS. Precise epidemiological data among survivors have revealed important clinical factors related to the risk of leukemias. In this review, by comparing data for secondary MDS and leukemia/MDS among survivors, several factors which would affect the risk of MDS, especially secondary MDS, are discussed.
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Metadaten
Titel
Lessons from the Atomic Bomb About Secondary MDS
verfasst von
Tomoko Hata
Daisuke Imanishi
Yasushi Miyazaki
Publikationsdatum
01.12.2014
Verlag
Springer US
Erschienen in
Current Hematologic Malignancy Reports / Ausgabe 4/2014
Print ISSN: 1558-8211
Elektronische ISSN: 1558-822X
DOI
https://doi.org/10.1007/s11899-014-0235-0

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