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Supportive Care in Cancer

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22.07.2018 | Letter to the Editor

Letter to the editor—comments on Kleckner et al. (2018) “Effects of exercise during chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial”

verfasst von: J.K. Vallance, K.A. Bolam

Erschienen in: Supportive Care in Cancer | Ausgabe 1/2019

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Excerpt

We read with interest the recent article by Kleckner et al. [1] examining the effects of a 6-week exercise program (EXCAP©®) among 355 cancer survivors (breast, lymphoma, colon, lung, and other) on chemotherapy-induced peripheral neuropathy (CIPN). We agree that CIPN is an important patient outcome in the exercise and cancer field. In their trial, the authors concluded “exercise appears to reduce CIPN symptoms in patients receiving taxane-, platinum-, or vinca alkaloid-based chemotherapy.” (p. 1019). In our opinion, while the study shows potentially positive trends, the conclusions drawn by the authors may be somewhat premature. …

Kleckner I, Kamen C, Gewandter JS, Mohile NA, Heckler CE, Culakova E, Fund C, Janelsins MC, Asare M, Po-Ju L, Reddy PS, Giguere J, Berenberg J, Kesler SR, Mustian KM (2018) Effects of exercise during chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial. Support Care Cancer 26:1019–1028CrossRef

Feise RJ (2002) Do multiple outcome measures require p-value adjustment? BMC Med Res Methodol 2:8CrossRefPubMedPubMedCentral

Mendoza TR, Zhao F, Cleeland CS, Wagner LI, Patrick-Miller LJ, Fisch MJ (2013) The validity and utility of the M. D. Anderson Symptom Inventory in patients with breast cancer: evidence from the Symptom Outcomes and Practice Patterns Data from the Eastern Cooperative Oncology Group. Clin Breast Cancer 13(5):325–334CrossRefPubMedPubMedCentral

Bao T, Basal C, Seluzicki C, Li SQ, Seidman AD, Mao JJ (2016) Long-term chemotherapy-induced peripheral neuropathy among breast cancer survivors: prevalence, risk factors, and fall risk. Breast Cancer Res Treat 159:327–333CrossRefPubMedPubMedCentral

Cella D, Peterman A, Hudgens S, Webster K, Socinski MA (2003) Measuring the side effects of taxane therapy in oncology: the functional assessment of cancer therapy-taxane (FACT-Taxane). Cancer 98:822–831CrossRefPubMed

Titel: Letter to the editor—comments on Kleckner et al. (2018) “Effects of exercise during chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial”
verfasst von: J.K. Vallance
K.A. Bolam
Publikationsdatum: 22.07.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Supportive Care in Cancer / Ausgabe 1/2019
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-018-4361-4

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18.04.2024 | Wirbelsäulenmetastase | Nachrichten

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Springer Medizin

Letter to the editor—comments on Kleckner et al. (2018) “Effects of exercise during chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial”

Excerpt

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Excerpt

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