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Open Access 10.06.2024 | LETTER

Letter to the Editor Regarding “VIVEX: A Formula for Calculating Individual Vitreous Volume: A New Approach Towards Tailored Patient Dosing Regime in Intravitreal Therapy”

verfasst von: Bilgehan Erduran, Nurullah Koçak

Erschienen in: Ophthalmology and Therapy | Ausgabe 8/2024

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This comment refers to the article available online at https://​doi.​org/​10.​1007/​s40123-023-00838-2.
An author’s reply to this comment is available online at https://​doi.​org/​10.​1007/​s40123-024-00975-2.
An author's reply to this comment is available online at https://​doi.​org/​10.​1007/​s40123-024-00975-2.
Dear Editor,
We were really excited to read the article about VIVEX [1], a new formula that allows us to calculate vitreous volume very easily. It is very common for ophthalmologists to perform intravitreal injections with standard doses based on the knowledge that the volume of the vitreous in an adult eye is approximately 4.0 ml. The authors’ motto “as much as necessary, as little as possible” is valuable for determining the amount of tamponade in future intravitreal surgeries and for patient-specific dosing of intravitreal injections.
Some articles reporting the relationship between lens thickness and age have shown a significant direct correlation between lens thickness and age [2, 3]. In this respect, it is valuable that the mean age of the patients in the emmetropic, myopic and hyperopic groups was close in this study. However, de Santana et al. proposed an equation to estimate the vitreous cavity volume (VCV) in pseudophakic patients based on the axial length of the eye and estimated that the VCV should be 0.6 to 0.7 mL less than in pseudophakic patients [4]. Tanaka et al. also measured the volume of vitreous changing with air in fluid–air exchange during vitrectomy in phakic patients only, to eliminate the difference that may occur as a result of lens condition [5]. Given this information, we noticed that Borkenstein et al.’s article did not mention the patients’ lens status. As the average age of the patients is around 60 years, the possibility of cataract surgery is on the agenda. For these reasons, we are curious about the effect of the lens status of the patients in this study on vitreous volume. We believe that by adding this information, the study will be more accurately interpreted and will better inform future research.

Declarations

Conflict of Interest

Bilgehan Erduran and Nurullah Koçak have nothing to disclose.

Ethical Approval

This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://​creativecommons.​org/​licenses/​by-nc/​4.​0/​.
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Titel
Letter to the Editor Regarding “VIVEX: A Formula for Calculating Individual Vitreous Volume: A New Approach Towards Tailored Patient Dosing Regime in Intravitreal Therapy”
verfasst von
Bilgehan Erduran
Nurullah Koçak
Publikationsdatum
10.06.2024
Verlag
Springer Healthcare
Erschienen in
Ophthalmology and Therapy / Ausgabe 8/2024
Print ISSN: 2193-8245
Elektronische ISSN: 2193-6528
DOI
https://doi.org/10.1007/s40123-024-00974-3

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