Dear Editor,
We were really excited to read the article about VIVEX [
1], a new formula that allows us to calculate vitreous volume very easily. It is very common for ophthalmologists to perform intravitreal injections with standard doses based on the knowledge that the volume of the vitreous in an adult eye is approximately 4.0 ml. The authors’ motto “as much as necessary, as little as possible” is valuable for determining the amount of tamponade in future intravitreal surgeries and for patient-specific dosing of intravitreal injections.
Some articles reporting the relationship between lens thickness and age have shown a significant direct correlation between lens thickness and age [
2,
3]. In this respect, it is valuable that the mean age of the patients in the emmetropic, myopic and hyperopic groups was close in this study. However, de Santana et al. proposed an equation to estimate the vitreous cavity volume (VCV) in pseudophakic patients based on the axial length of the eye and estimated that the VCV should be 0.6 to 0.7 mL less than in pseudophakic patients [
4]. Tanaka et al. also measured the volume of vitreous changing with air in fluid–air exchange during vitrectomy in phakic patients only, to eliminate the difference that may occur as a result of lens condition [
5]. Given this information, we noticed that Borkenstein et al.’s article did not mention the patients’ lens status. As the average age of the patients is around 60 years, the possibility of cataract surgery is on the agenda. For these reasons, we are curious about the effect of the lens status of the patients in this study on vitreous volume. We believe that by adding this information, the study will be more accurately interpreted and will better inform future research.
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