Level 5 Lymphadenopathy Warrants Heightened Suspicion for Clinically Significant Pathology
- 03.06.2016
- Original Paper
Erschienen in:
- Verfasst von
- M. Cunnane
- L. Cheung
- A. Moore
- S. di Palma
- A. McCombe
- L. Pitkin
- Erschienen in
- Head and Neck Pathology | Ausgabe 4/2016
Abstract
We conclude that patients presenting with level 5 lymphadenopathy should be investigated with heightened clinical vigilance. Our results suggest that up to 80 % will harbour clinically significant pathology requiring further medical treatment, three quarters of which will be malignancy. We report an observational study of histological outcomes of level 5 lymph node biopsies from a regional histopathology department across 5 years. 184 subjects were identified as having a biopsy of a lymph node from the level 5 region within the study period. One hundred and fifty six cases (84.8 %) had clinically significant pathology on final histology requiring further medical treatment. Lymphoma accounted for the highest number of cases (n = 72, 39.1 %), followed by metastatic carcinoma (n = 65, 35.3 %) and granulomatous change (n = 17, 9.2 %). Gender and laterality were not shown to be independent predictors of pathology significance (p > 0.05).
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- Titel
- Level 5 Lymphadenopathy Warrants Heightened Suspicion for Clinically Significant Pathology
- Verfasst von
-
M. Cunnane
L. Cheung
A. Moore
S. di Palma
A. McCombe
L. Pitkin
- Publikationsdatum
- 03.06.2016
- Verlag
- Springer US
- Erschienen in
-
Head and Neck Pathology / Ausgabe 4/2016
Elektronische ISSN: 1936-0568 - DOI
- https://doi.org/10.1007/s12105-016-0733-6
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