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Erschienen in: European Radiology 1/2019

02.08.2018 | Computed Tomography

LI-RADS v2017 categorisation of HCC using CT: Does moderate to severe fatty liver affect accuracy?

verfasst von: Seung Soo Kim, Jeong Ah Hwang, Hyeong Cheol Shin, Seo-Youn Choi, Tae Wook Kang, Sung Shick Jou, Woong Hee Lee, Suyeon Park, Nam Hun Heo

Erschienen in: European Radiology | Ausgabe 1/2019

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Abstract

Objectives

To compare the sensitivity of Liver Imaging Reporting and Data System (LI-RADS) v2017 for diagnosis of hepatocellular carcinoma (HCC) using multiphasic computed tomography (CT) between patients with and without moderate to severe fatty liver (MSFL).

Methods

This retrospective study included a total of 106 high-risk patients with 112 pathologically proven HCCs who underwent multiphasic CT. Patients were classified as MSFL (24 men, 2 women; mean age, 59.5 years [range, 38–79 years]) and non-MSFL (64 men, 16 women; mean age, 62.9 years [range, 40–89 years]) groups according to unenhanced CT liver and spleen parenchymal attenuation. Two independent radiologists assigned LI-RADS categories and accessed HCC features on CT. Sensitivities for LR-5 assignment and frequencies of HCC features were compared between the two groups.

Results

Sensitivities of LR-5 assignment for diagnosing HCCs were not significantly different between MSFL and non-MSFL groups (65.4% [17/26] vs. 76.7% [66/86] for reviewer 1, p = 0.247; 73.1% [19/26] vs. 76.74% [66/86] for reviewer 2, p = 0.702). No significant differences in the frequencies of arterial hyperenhancement, washout, and capsule were observed between the two groups (96.2% [25/26] vs. 98.8% [85/86], p = 0.412; 80.8% [21/26] vs. 89.5% [77/86], p = 0.308; and 53.8% [14/26] vs. 57% [49/86], p = 0.778, respectively).

Conclusions

LI-RADS v2017 using CT showed comparable sensitivity for diagnosing HCC regardless of MSFL.

Key Points

• Using LI-RADS v2017 with CT, diagnosis of HCC in patients with MSFL showed similar sensitivity to that in patients without MSFL.
• Frequencies of major HCC features (arterial hyperenhancement, washout, and capsule) on CT between the MSFL and non-MSFL groups were not significantly different.
• LI-RADS using CT may be feasible for diagnosing HCC in patients with fatty liver.
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Metadaten
Titel
LI-RADS v2017 categorisation of HCC using CT: Does moderate to severe fatty liver affect accuracy?
verfasst von
Seung Soo Kim
Jeong Ah Hwang
Hyeong Cheol Shin
Seo-Youn Choi
Tae Wook Kang
Sung Shick Jou
Woong Hee Lee
Suyeon Park
Nam Hun Heo
Publikationsdatum
02.08.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 1/2019
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-018-5657-y

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