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Annals of Hematology

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01.11.2003 | Case Report

Life-threatening thrombotic thrombocytopenic purpura (TTP) in a patient with sickle cell-hemoglobin C disease

verfasst von: H. E. Lee, V. J. Marder, L. J. Logan, S. Friedman, B. J. Miller

Erschienen in: Annals of Hematology | Ausgabe 11/2003

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Abstract

We report a patient with hemoglobin sickle cell-hemoglobin C disease who developed the clinical syndrome of thrombotic thrombocytopenic purpura (TTP) during admission for typical acute pain crisis. The potential for multiorgan involvement secondary to vaso-occlusive crisis complicated the diagnosis and overlapped with the patient's clinical presentation of chronic bone pain and hemolytic anemia. Clinical improvement and normalization of laboratory parameters followed rapidly in response to plasma exchange therapy.

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Titel: Life-threatening thrombotic thrombocytopenic purpura (TTP) in a patient with sickle cell-hemoglobin C disease
verfasst von: H. E. Lee
V. J. Marder
L. J. Logan
S. Friedman
B. J. Miller
Publikationsdatum: 01.11.2003
Verlag: Springer-Verlag
Erschienen in: Annals of Hematology / Ausgabe 11/2003
Print ISSN: 0939-5555
Elektronische ISSN: 1432-0584
DOI: https://doi.org/10.1007/s00277-003-0715-0

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Life-threatening thrombotic thrombocytopenic purpura (TTP) in a patient with sickle cell-hemoglobin C disease

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