Regular ArticleEvaluating the Empirical Support for the Geschwind-Behan-Galaburda Model of Cerebral Lateralization
References (0)
Cited by (200)
Elevated levels of mixed-hand preference in dyslexia: Meta-analyses of 68 studies
2023, Neuroscience and Biobehavioral ReviewsYakovlevian Torque: Something Old and Something New
2022, Biological PsychiatryDump the “dimorphism”: Comprehensive synthesis of human brain studies reveals few male-female differences beyond size
2021, Neuroscience and Biobehavioral ReviewsAn examination of the influence of prenatal sex hormones on handedness: Literature review and amniotic fluid data
2021, Hormones and BehaviorCitation Excerpt :Second, the Geschwind-Behan-Galaburda model (hereafter GBG) (Geschwind and Behan, 1982; Geschwind and Galaburda, 1985a, 1985b, 1985c, 1987) suggests that exposure to high levels of testosterone during gestation slows development of the left cerebral hemisphere, which can result in ‘anomalous dominance’, a term that is used to cover a range of phenomena including right hemisphere (or bilateral) speech representation, and left-handedness. Although the theory has at times been heavily criticised (see Bryden et al., 1994), many researchers have continued to test hypotheses derived from it (e.g., Beaton et al., 2011; Beaton et al., 2012; Kalmady et al., 2013; Stoyanov et al., 2011; Tran et al., 2014). Analogous with the sexual differentiation hypothesis, GBG theory predicts that high levels of foetal testosterone exposure will associate with left-handedness.
Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment
2020, CortexCitation Excerpt :It has also been reported that foetal testosterone levels relate to the development of grey matter asymmetries of some cortical regions, including the PT (Lombardo et al., 2012). In fact, an extensive and influential theory was developed by Geschwind and Galaburda which involves sex hormones, brain laterality and disorder susceptibility (Geschwind & Galaburda, 1985), which still motivates current research, although definitive support is lacking (Bryden, McManus, & Bulman-Fleming, 1994; Hollier, Maybery, Keelan, Hickey, & Whitehouse, 2014; Papadatou-Pastou & Martin, 2017). In the present study, we used the UK Biobank MRI dataset (N = 18,057) to perform a more highly powered genetic analysis of PT asymmetry than has previously been possible.
The role of sex hormones in human language development
2020, Neuroendocrine Regulation of Animal Vocalization: Mechanisms and Anthropogenic Factors in Animal Communication