Regular articleNonsteroidal anti-inflammatory drugs differentially regulate cytokine production in human lymphocytes : Up-regulation of TNF, IFN-γ and IL-2, in contrast to down-regulation of IL-6 production
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Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning
2020, Brain, Behavior, and ImmunityCitation Excerpt :That is, it is certainly possible that either women overestimated their activity resulting in an apparent greater male benefit at seemingly similar activity levels, or that men are engaged in more intensive physical activities that are not qualitatively captured on our self-report measure (e.g., jogging at the same frequency but a faster speed). We also did not systematically capture common medication regimens known to target immune-mediated processes (e.g., NSAIDs, corticosteroids, TNF inhibitors) (Tsuboi et al., 1995; Wallen et al., 1991), and may be an important confounder to evaluate in future works. Additionally, the observational design of the study inherently limits determination of causality, as it is possible that older adults with poorer overall functioning (e.g., poorer immune, cardiovascular, neurobehavioral health) are engaging in less physical activity.
Correlation of cytokines, BDNF levels, and memory function in patients with opioid use disorder undergoing methadone maintenance treatment
2018, Drug and Alcohol DependenceCitation Excerpt :If participants reported taking these agents during follow up, we excluded their cytokine data. Glucocorticoids inhibit the expression and action of most cytokines, including IL-1β, TNF-α, IL-2, IL-3, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12 and IFN-γ (Tsuboi et al., 1995). NSAIDs might also affect the responses of IL-2, IL-6, IL-8, and monocyte chemoattractant protein-1 (Lisboa et al., 2017).
Diclofenac inhibits 27-hydroxycholesterol-induced inflammation
2016, Biochemical and Biophysical Research CommunicationsAntenatal exposure to indomethacin increases the risk of severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia: A systematic review with metaanalysis
2015, American Journal of Obstetrics and GynecologyComparative analysis of innate immune system function in metastatic breast, colorectal, and prostate cancer patients with circulating tumor cells
2014, Experimental and Molecular Pathology