Short CommunicationExpression and Cytogenetic Localization of the Human SM22 Gene (TAGLN)☆
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2019, EBioMedicineCitation Excerpt :It is important to note that all of the normal bladder tissues that were used in this study were complex tissues that were not subject to microdissection and consisted not only of bladder epithelial cell but also stromal cells and smooth muscle cells (SMCs). It is well known that TAGLN is an abundant protein in SMCs [47,48]. According to the IHC results obtained from the PKU-BLCA cohort, SMCs were found in almost all of the normal bladder samples (Supplementary Fig.S4a).
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2013, TheriogenologyCitation Excerpt :Indeed, its mRNA levels are highest in adult human tissues containing large amounts of smooth muscle, such as uterus, bladder, stomach, and prostate. However, it is also expressed in several adult tissues containing little or no smooth muscle, including spinal chord, adrenal gland, and, notably, in the heart [53,60]. As we have shown in the epithelial cell seminal vesicles, from these Saharan rodents, P. obesus, Meriones libycus, Meriones shawi, and Meriones crassus, transgelin expression has also been identified recently in epithelial cells than in intestinal epithelial cells [36], glomerular epithelial cells [37], breast ductal epithelium [36,61], and prostate epithelium [38].
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Sequence data for the human SM22 (TAGLN) promoter and gene have been deposited with the GenBank Data Library under Accession Nos. AF013710 and AF013711, respectively.
- 1
Co-first authors.
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To whom correspondence should be addressed at University of Chicago, 5841 S. Maryland Avenue, MC6026, Chicago, IL 60637. Telephone: (773) 702-6790. Fax: (773) 702-4736. E-mail:[email protected].