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Principles of Surgical Therapy in Oncology

  • Chapter
Oncology

Abstract

The role of surgery in the treatment of cancer has seen a dramatic change over the past century, from that of the only chance for cure to becoming one weapon in an armamentarium of oncologic therapies. As the role of surgery changes, so has the role of the surgeon, evolving from cancer surgeon to surgical oncologist. This role continues to evolve, as the management of cancer is altered by increased knowledge of genetics, molecular biology, and tumor immunology. Although surgery has historically been the first line of defense against a tumor, the escalating use of neoadjuvant therapies often shifts surgery to the second or third line. The role of surgery has expanded from that of purely therapeutic to include both palliation and prophylaxis. Inasmuch as surgeons are the ones with direct access to tumors, they have cemented their role as physician-scientists, investigating novel molecular and immunologic therapies. As new discoveries continue to transform our approach to cancer, the field of surgical oncology will continue to evolve (Table 4.1).

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Author information

Authors and Affiliations

  1. Division of Surgical Oncology, Department of Surgery, University of Michigan, Ann Arbor, MI, USA

    Michael S. Sabel MD (Assistant Professor), Kathleen M. Diehl MD (Assistant Professor) & Alfred E. Chang MD (Hugh Cabot Professor of Surgery; Chief)

Authors
  1. Michael S. Sabel MD
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  2. Kathleen M. Diehl MD
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  3. Alfred E. Chang MD
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Editor information

Editors and Affiliations

  1. Division of Surgery Oncology, Department of Surgery, University of Michigan, Ann Arbor, MI, USA

    Alfred E. Chang MD (Hugh Cabot Professor of Surgery and Chief) (Hugh Cabot Professor of Surgery and Chief)

  2. Breast Oncology Program, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA

    Daniel F. Hayes MD (Clinical Director) (Clinical Director)

  3. Department of Cardiothoracic Surgery, New York University School of Medicine and Comprehensive Cancer Center, New York, NY, USA

    Harvey I. Pass MD (Professor and Chief of Thoracic Surgery and Head) (Professor and Chief of Thoracic Surgery and Head)

  4. Thoracic Oncology, New York University School of Medicine and Comprehensive Cancer Center, New York, NY, USA

    Harvey I. Pass MD (Professor and Chief of Thoracic Surgery and Head) (Professor and Chief of Thoracic Surgery and Head)

  5. Department of Medicine, Harvard Medical School, USA

    Richard M. Stone MD (Associate Professor and Clinical Director) (Associate Professor and Clinical Director)

  6. Adult Leukemia Program, Dana-Farber Cancer Institute, Boston, MA, USA

    Richard M. Stone MD (Associate Professor and Clinical Director) (Associate Professor and Clinical Director)

  7. Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center at UCLA, USA

    Patricia A. Ganz MD (American Cancer Society Clinical Research Professor, Director and Professor) (American Cancer Society Clinical Research Professor, Director and Professor)

  8. Schools of Public Health and Medicine, University of California, Los Angeles, Los Angeles, CA, USA

    Patricia A. Ganz MD (American Cancer Society Clinical Research Professor, Director and Professor) (American Cancer Society Clinical Research Professor, Director and Professor)

  9. Department of Radiation Oncology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, USA

    Timothy J. Kinsella MD (Vincent K. Smith Professor and Chairman) (Vincent K. Smith Professor and Chairman)

  10. Department of Medicine, University of Wisconsin Comprehensive Cancer Center, Madison, WI, USA

    Joan H. Schiller MD (Melanie Heald Professor of Medical Oncology) (Melanie Heald Professor of Medical Oncology)

  11. Health Media Research Laboratory, Department of Health Behavior and Health Education, University of Michigan School of Public Health, USA

    Victor J. Strecher PhD, MPH (Professor and Director and Associate Director) (Professor and Director and Associate Director)

  12. Cancer Prevention and Control, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA

    Victor J. Strecher PhD, MPH (Professor and Director and Associate Director) (Professor and Director and Associate Director)

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Sabel, M.S., Diehl, K.M., Chang, A.E. (2006). Principles of Surgical Therapy in Oncology. In: Chang, A.E., et al. Oncology. Springer, New York, NY. https://doi.org/10.1007/0-387-31056-8_4

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  • DOI: https://doi.org/10.1007/0-387-31056-8_4

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-24291-0

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