Overview
- Editors:
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Gordon D. Brown
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University of Cape Town, Cape Town, South Africa
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Mihai G. Netea
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Radboud University Nijmegen, Nijmegen, The Netherlands
- A definitive text covering all aspects of the immunology of fungal infections
- Chapters written by leading experts in the field
- Detailed coverage of each component of immunity and their relation to fungal infection
- Specific attention to the immunology of selected fungal pathogens
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Table of contents (21 chapters)
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Front Matter
Pages I-XVIII
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Cells
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- Sigrid E.M. Heinsbroek, Siamon Gordon
Pages 3-25
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- David H. Dockrell, Emmet E. McGrath, Moria K.B. Whyte, Ian Sabroe
Pages 51-73
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- Anna Vecchiarelli, Antonella Mencacci, Francesco Bistoni
Pages 75-97
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- Jeremy C.D. Wiseman, Christopher H. Mody
Pages 99-130
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- Robert B. Ashman, Camile S. farah, Christine Wells
Pages 131-148
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Soluble Factors
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Front Matter
Pages 149-149
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- Uday Kishore, Kenneth B.M. Reid
Pages 151-176
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- Cornelia Speth, Cornelia Lass-Flörl, Reinhard Würzner
Pages 177-199
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- Karen F. Buckland, Cory M. Hogaboam
Pages 201-234
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- José L. Lòpez-Ribot, RosalÍa DÍez-Orejas, Concha Gil
Pages 235-256
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Non-Opsonic Fungal Receptors
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Front Matter
Pages 257-257
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- Mihai G. Netea, Jos W.M. Van der Meer, Bart Jan Kullberg
Pages 259-272
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- S. Vicky Tsoni, Gordon D. Brown
Pages 273-292
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- F. Meyer-Wentrup, A. Cambi, C.G. Figdor, G.J. Adema
Pages 293-307
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Immunity to Specific Pathogens
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Front Matter
Pages 309-309
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- Laura McKinley, Chad Steele
Pages 311-330
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- Jean-Paul Latgé, Anne Beauvais
Pages 331-360
About this book
The history of mankind has been shaped by infections, more than by war and famine together. At the same time, however, the development of society has had an equally important effect on human diseases. The emergence of agriculture, urban societies and high population densities has been proven to be crucial for the spread of pathogens, and thus human action is currently the single most important driver of infectious epidemiology. Even today, where once major killers such as poliomyelitis have been eradicated, new pathogens are appearing as result of human activity. One such group of pathogens are the fungi, whose emergence is mainly due to modern medical practices. Fungal microorganisms, from yeasts colonizing the skin or mucosa, to molds from soil or water, are usually harmless in the context of normal host responses. However, the success of chemotherapy, as well as the AIDS pandemia, has led to immune deficiencies in a significant segment of the patient population, and the extensive use of intravenous catheters has provided a way of access for microorganisms which otherwise would find difficult to infect the host. As a result, a yeast such as Candida is now on the 4th place on the list of the most frequent sepsis agents, whereas infection with the mold Aspergillus is increasing in incidence and it is one of the most feared complications in patients with hematological malignancies.
Editors and Affiliations
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University of Cape Town, Cape Town, South Africa
Gordon D. Brown
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Radboud University Nijmegen, Nijmegen, The Netherlands
Mihai G. Netea
