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Epo Delivery by Genetically Engineered C2C12 Myoblasts Immobilized in Microcapsules

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Book cover Therapeutic Applications of Cell Microencapsulation

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 670))

Abstract

Over the last half century, the use of erythropoietin (Epo) in the management of malignancies has been extensively studied. Originally viewed as the renal hormone responsible for red blood cell production, many recent in vivo and clinical approaches demonstrate that various tissues locally produce Epo in response to physical or metabolic stress. Thus, not only its circulating erythrocyte mass regulator activity but also the recently discovered nonhematological actions are being thoroughly investigated in order to fulfill the specific Epo delivery requirements for each therapeutic approach.

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  1. Faculty of Pharmacy, Laboratory of Pharmacy and Pharmaceutical Technology, University of the Basque Country, Vitoria-Gasteiz, Spain

    Ainhoa Murua, Gorka Orive, Rosa M Hernández & José Luis Pedraz

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  1. Ainhoa Murua
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  1. Laboratory of Pharmacy and Pharmaceutical Technology, University of the Basque Country, Vitoria-Gasteiz, Spain

    José Luis Pedraz PHD  & Gorka Orive PhD  & 

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Murua, A., Orive, G., Hernández, R.M., Pedraz, J.L. (2010). Epo Delivery by Genetically Engineered C2C12 Myoblasts Immobilized in Microcapsules. In: Pedraz, J.L., Orive, G. (eds) Therapeutic Applications of Cell Microencapsulation. Advances in Experimental Medicine and Biology, vol 670. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5786-3_6

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