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Multi-Modality Atherosclerosis Imaging and Diagnosis pp 123–128Cite as

Clinical CT Imaging of Carotid Arteries

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Abstract

A better understanding of the role of carotid plaque components in predicting ischemic stroke will be important in designing future treatment trials for carotid artery stenosis. A decade ago, studies demonstrated a clear advantage in certain populations of endarterectomy compared with medical therapy. However, these studies were conducted before the widespread use of medical treatments that have been demonstrated to reduce stroke risk in patients with vascular disease, such as clopidogrel; extended-release dipyridamole; and aspirin, statins, and more aggressive blood pressure control. With the development of both improved medical therapy and less invasive percutaneous stenting approaches over the last few years, some of the same questions must be addressed again. Should our hypotheses prove correct, these results will provide a relevant, standardized, and validated method of interpreting the carotid artery wall findings using a routine imaging technique that could be used in future trials to monitor the carotid wall composition, both to select patients for treatment and to determine whether drug treatments are effective in altering the size and composition of the atheroma.

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Authors and Affiliations

  1. Diagnostic and Interventional Neuroradiology Division, Department of Radiology and Medical Imaging, University of Virginia, 800170, 1215 Lee Street, Charlottesville, VA, 22903, USA

    Chandra dev Sahu M.D & Max Wintermark M.D

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  1. Chandra dev Sahu M.D
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  2. Max Wintermark M.D
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Correspondence to Max Wintermark M.D .

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Editors and Affiliations

  1. Department of Radiology, A.O.U Cagliari - Polo di Monserrato, Bivio per Sestu, Italy

    Luca Saba

  2. Instituto Superior Técnico Institute for Systems and Robotics, Lisboa, Portugal

    João Miguel Sanches

  3. Hospital de Santa Maria, Lisboa, Portugal

    Luís Mendes Pedro

  4. Stroke Research and Monitoring Division, AtheroPoint(TM) LLC, Roseville, California, USA

    Jasjit S. Suri

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dev Sahu, C., Wintermark, M. (2014). Clinical CT Imaging of Carotid Arteries. In: Saba, L., Sanches, J., Pedro, L., Suri, J. (eds) Multi-Modality Atherosclerosis Imaging and Diagnosis. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7425-8_10

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  • DOI: https://doi.org/10.1007/978-1-4614-7425-8_10

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