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Clinical Research in Diabetes and Obesity pp 249–274Cite as

Insulin Resistance in the Polycystic Ovary Syndrome

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Part of the book series: Contemporary Biomedicine ((CB,volume 15))

Abstract

Polycystic ovary syndrome (PCOS) is an exceptionally common disorder of premenopausal women characterized by hyperandrogenism and chronic anovulation (1). Although there have been no specific population-based studies, a 5–10% prevalence of this disorder in women of reproductive age is probably a reasonable conservative estimate. This is based as an upper limit on studies of the prevalence of polycystic ovaries, which found that ∼20% of self-selected normal women had polycystic ovary morphology on ovarian ultrasound (2). Many of these women had subtle endocrine abnormalities (2). The lower estimate is based on the reported 3% prevalence rate of secondary amenorrhea for three or more months (3) and the fact that up to ∼75% of women with secondary amenorrhea will fulfill diagnostic criteria for PCOS (4). PCOS women can also have less profound disturbances in menstrual function (1,2).

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Authors
  1. Andrea Dunaif
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  2. Carol Beth Book
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Editors and Affiliations

  1. Veteran’s Affairs Medical Center, Denver, CO, USA

    Boris Draznin

  2. Mayo Clinic, Rochester, MN, USA

    Robert Rizza

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Dunaif, A., Book, C.B. (1997). Insulin Resistance in the Polycystic Ovary Syndrome. In: Draznin, B., Rizza, R. (eds) Clinical Research in Diabetes and Obesity. Contemporary Biomedicine, vol 15. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4757-3906-0_14

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  • DOI: https://doi.org/10.1007/978-1-4757-3906-0_14

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-051-9

  • Online ISBN: 978-1-4757-3906-0

  • eBook Packages: Springer Book Archive

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