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The Mechanics and Biophysics of Hearing pp 69–75Cite as

Fast Outer Hair Cell Motility: How Fast is Fast?

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Part of the book series: Lecture Notes in Biomathematics ((LNBM,volume 87))

Abstract

Recent experiments have implicated transmembrane voltage as the driving force of OHC motility (Santos-Sacchi and Dilger, 1988a,b; Iwasa and Kachar, 1989). A voltage dependence of OHC motility clearly implies that a charged voltage sensing particle must reside in the OHC membrane, and as was predicted for voltage dependent ionic channels (Hodgkin and Huxley, 1952), particle movement should occur under an applied transmembrane voltage. Gating currents associated with the movement of the presumed voltage sensor in OHCs have been described by Ashmore (1989).

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References

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Author information

Authors and Affiliations

  1. Laboratory of Otolaryngology, New Jersey Medical School, 07103, Newark, N. J., USA

    J. Santos-Sacchi

Authors
  1. J. Santos-Sacchi
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Editor information

Editors and Affiliations

  1. Auditory Physiology Laboratory and Department of Neurobiology and Physiology, Northwestern University, 60208, Evanston, IL, USA

    Peter Dallos

  2. Department of Neurophysiology and Department of Electrical and Computer Engineering, University of Wisconsin-Madison, 53706, Madison, WI, USA

    C. Daniel Geisler

  3. Computer Systems Laboratory, Washington University, 63110, St. Louis, MO, USA

    John W. Matthews

  4. Department of Otolaryngology, University of Minnesota, 55414, Minneapolis, MN, USA

    Mario A. Ruggero

  5. Division of Applied Mechanics, Stanford University, 94305, Stanford, CA, USA

    Charles R. Steele

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© 1990 Springer-Verlag Berlin Heidelberg

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Santos-Sacchi, J. (1990). Fast Outer Hair Cell Motility: How Fast is Fast?. In: Dallos, P., Geisler, C.D., Matthews, J.W., Ruggero, M.A., Steele, C.R. (eds) The Mechanics and Biophysics of Hearing. Lecture Notes in Biomathematics, vol 87. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4341-8_9

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  • DOI: https://doi.org/10.1007/978-1-4757-4341-8_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-97473-6

  • Online ISBN: 978-1-4757-4341-8

  • eBook Packages: Springer Book Archive

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