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Selective Toxicity

The physico-chemical basis of therapy

  • Book
  • © 1973

Overview

Authors:
  1. Adrien Albert

    1. Australian Academy of Science, Department of Medical Chemistry in the John Curtin School of Medical Research, Australian National University, Canberra, Australia

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xv
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  2. Topics of general interest

    1. Front Matter

      Pages 1-1
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    2. Toxicity in the service of man

      • Adrien Albert
      Pages 3-16

    3. Differences in distribution: the first principle of selectivity

      • Adrien Albert
      Pages 17-62

    4. Comparative biochemistry: the second principle of selectivity

      • Adrien Albert
      Pages 63-108

    5. Comparative cytology: the third principle of selectivity

      • Adrien Albert
      Pages 109-129

    6. Chemotherapy: history and principles

      • Adrien Albert
      Pages 130-172

    7. Pharmacodynamics

      • Adrien Albert
      Pages 173-211

  3. The relationship between molecular structure and biological activity

    1. Front Matter

      Pages 213-213
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    2. Structure-activity relationships. The nature of chemical bonds. Adsorption. The influence of seemingly inert groups on biological action

      • Adrien Albert
      Pages 215-242

    3. Metabolites, enzymes, and metabolite analogues

      • Adrien Albert
      Pages 243-281

    4. Ionization

      • Adrien Albert
      Pages 282-333

    5. Metal-binding substances

      • Adrien Albert
      Pages 334-391

    6. The covalent bond in selective toxicity

      • Adrien Albert
      Pages 392-423

    7. Steric factors

      • Adrien Albert
      Pages 424-465

    8. Surface chemistry. The modification of membranes by surface-active agents

      • Adrien Albert
      Pages 466-478

    9. Free radicals

      • Adrien Albert
      Pages 479-485

    10. Biological activity unrelated to structure. Ferguson’s Principle

      • Adrien Albert
      Pages 486-497

  4. Back Matter

    Pages 499-597
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Keywords

Authors and Affiliations

  • Australian Academy of Science, Department of Medical Chemistry in the John Curtin School of Medical Research, Australian National University, Canberra, Australia

    Adrien Albert

Bibliographic Information

  • Book Title: Selective Toxicity

  • Book Subtitle: The physico-chemical basis of therapy

  • Authors: Adrien Albert

  • DOI: https://doi.org/10.1007/978-1-4899-7130-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Adrien Albert 1973

  • Softcover ISBN: 978-0-412-10810-5Published: 01 January 1973

  • eBook ISBN: 978-1-4899-7130-2Published: 27 November 2013

  • Edition Number: 5

  • Number of Pages: XV, 597

  • Number of Illustrations: 17 b/w illustrations

  • Topics: Pharmacology/Toxicology

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